DK1762626T3 - Signalamplifikation under anvendelse af et syntetisk zymogen - Google Patents

Signalamplifikation under anvendelse af et syntetisk zymogen

Info

Publication number
DK1762626T3
DK1762626T3 DK06011717.3T DK06011717T DK1762626T3 DK 1762626 T3 DK1762626 T3 DK 1762626T3 DK 06011717 T DK06011717 T DK 06011717T DK 1762626 T3 DK1762626 T3 DK 1762626T3
Authority
DK
Denmark
Prior art keywords
zymogens
signal amplification
enzyme
substrate
synthetic zymogen
Prior art date
Application number
DK06011717.3T
Other languages
English (en)
Inventor
Gerard J Colpas
Mitchell C Sanders
Shite Sebastian
Original Assignee
Systagenix Wound Man Ip Co Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systagenix Wound Man Ip Co Bv filed Critical Systagenix Wound Man Ip Co Bv
Application granted granted Critical
Publication of DK1762626T3 publication Critical patent/DK1762626T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/10—Enterobacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/14—Streptococcus; Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK06011717.3T 2003-09-02 2004-09-02 Signalamplifikation under anvendelse af et syntetisk zymogen DK1762626T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49984603P 2003-09-02 2003-09-02
EP04783048A EP1670936A1 (en) 2003-09-02 2004-09-02 Signal amplification using a synthetic zymogen

Publications (1)

Publication Number Publication Date
DK1762626T3 true DK1762626T3 (da) 2011-03-14

Family

ID=34272880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06011717.3T DK1762626T3 (da) 2003-09-02 2004-09-02 Signalamplifikation under anvendelse af et syntetisk zymogen

Country Status (11)

Country Link
US (2) US8039228B2 (da)
EP (2) EP1762626B1 (da)
JP (3) JP2007503833A (da)
AT (1) ATE491806T1 (da)
AU (3) AU2004269425A1 (da)
CA (2) CA2537529A1 (da)
DE (1) DE602004030623D1 (da)
DK (1) DK1762626T3 (da)
ES (1) ES2357547T3 (da)
PT (1) PT1762626E (da)
WO (1) WO2005021780A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063693A2 (en) 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms
ES2357547T3 (es) * 2003-09-02 2011-04-27 Systagenix Wound Management Ip Co. Bv. Amplificación de señal usando un zimogeno sintético.
CA2557612C (en) 2003-11-03 2014-06-17 Ethicon, Inc. Methods, peptides and biosensors useful for detecting a broad spectrum of bacteria
DE602004021281D1 (de) * 2003-11-03 2009-07-09 Ethicon Inc Kolorimetrische substrate, kolorimetrische sensoren und verwendungsverfahren
JP5089058B2 (ja) * 2006-03-01 2012-12-05 旭化成ファーマ株式会社 試料中の銅イオン濃度測定用酵素
AT509355B1 (de) * 2010-02-10 2012-04-15 Univ Graz Tech Testanordnung
GB201116523D0 (en) 2011-09-23 2011-11-09 Systagenix Wound Man Ip Co Bv Wound prognosis
EP2896963B1 (en) 2011-01-31 2019-01-30 Woundchek Laboratories B.V. Wound prognosis
EP2685999A4 (en) 2011-03-18 2015-07-15 Univ Duke PEPTIDES FOR THE SUPPRESSION OF IGNITION
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
JP5903492B2 (ja) * 2011-09-16 2016-04-13 クレド バイオメディカル ピーティーイー リミテッド 分子診断アッセイデバイス及び使用方法
US9970933B2 (en) * 2011-10-06 2018-05-15 Ingibio, Ltd. Method for manufacturing multiple-diagnosis membrane sensor by using screen printing
US10087582B2 (en) * 2013-03-20 2018-10-02 Metgen Oy Method for saving energy in paper production
EP3155881A4 (en) * 2014-06-10 2018-03-21 Thomson Licensing Set top box having paste-in-hole tuner shield
CN110268054A (zh) * 2016-11-16 2019-09-20 通用生物传感器有限公司 切割事件转导方法和产品
CN106916797B (zh) * 2017-02-27 2019-12-17 中国科学院成都生物研究所 一种高活性漆酶突变体蛋白及其制备方法

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AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
JPH0480651A (ja) * 1990-07-23 1992-03-13 Kanzaki Paper Mfg Co Ltd 固定化酵素を用いるフロー型測定装置
JP3074361B2 (ja) * 1992-07-15 2000-08-07 セイコーインスツルメンツ株式会社 定量分析装置
ATE226642T1 (de) * 1994-07-07 2002-11-15 Tno Modifizierte proenzyme als substrate für proteolische enzyme
JPH08332077A (ja) * 1995-06-07 1996-12-17 Hitachi Ltd サンプルカップおよび生化学分析装置
JPH0923898A (ja) * 1995-07-13 1997-01-28 Nissui Pharm Co Ltd フェニルアラニンデアミナーゼ試験用反応シート
US20030096315A1 (en) 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
US20020187481A1 (en) * 2000-08-22 2002-12-12 Ramberg Elliot R. Methods and compositions for ultral low copy number analyte detection
JP4830079B2 (ja) 2000-11-29 2011-12-07 国立感染症研究所長 プロテアーゼ活性の測定方法
WO2002082078A2 (en) * 2001-04-09 2002-10-17 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Activated enzyme-linked detection systems for detecting and quantifying nucleid acids, antigens antibodies and other analytes
JP2003169697A (ja) * 2001-12-05 2003-06-17 Fuji Electric Co Ltd 水中のリン酸計測方法と装置
CA2474130C (en) 2002-01-29 2011-04-05 Pyare Khanna Enzyme activation protease assay
WO2003063693A2 (en) 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms
AU2003291135A1 (en) 2002-11-26 2004-06-18 Expressive Constructs, Inc. Methods, biosensors and kits for detecting and identifying fungi
AU2004225575B2 (en) 2003-01-31 2008-02-21 Ethicon, Inc. Method for detecting escherichia coli
ES2357547T3 (es) 2003-09-02 2011-04-27 Systagenix Wound Management Ip Co. Bv. Amplificación de señal usando un zimogeno sintético.
DE602004021281D1 (de) 2003-11-03 2009-07-09 Ethicon Inc Kolorimetrische substrate, kolorimetrische sensoren und verwendungsverfahren

Also Published As

Publication number Publication date
DE602004030623D1 (de) 2011-01-27
CA2537529A1 (en) 2005-03-10
WO2005021780A1 (en) 2005-03-10
JP4991251B2 (ja) 2012-08-01
CA2564426C (en) 2013-01-08
AU2008203204A1 (en) 2008-08-07
JP2007503833A (ja) 2007-03-01
ATE491806T1 (de) 2011-01-15
AU2011202044A1 (en) 2011-05-26
EP1762626B1 (en) 2010-12-15
US8039228B2 (en) 2011-10-18
US20070122873A1 (en) 2007-05-31
EP1670936A1 (en) 2006-06-21
US7566564B2 (en) 2009-07-28
ES2357547T3 (es) 2011-04-27
JP2007044052A (ja) 2007-02-22
EP1762626A1 (en) 2007-03-14
JP2012120541A (ja) 2012-06-28
PT1762626E (pt) 2011-01-28
US20070196881A1 (en) 2007-08-23
AU2004269425A1 (en) 2005-03-10
CA2564426A1 (en) 2005-03-10

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