DK1765844T3 - Purin-nukleotidderivater - Google Patents

Purin-nukleotidderivater

Info

Publication number
DK1765844T3
DK1765844T3 DK05755520.3T DK05755520T DK1765844T3 DK 1765844 T3 DK1765844 T3 DK 1765844T3 DK 05755520 T DK05755520 T DK 05755520T DK 1765844 T3 DK1765844 T3 DK 1765844T3
Authority
DK
Denmark
Prior art keywords
nucleotide derivatives
purine nucleotide
purine
derivatives
nucleotide
Prior art date
Application number
DK05755520.3T
Other languages
English (en)
Inventor
Vidar Bjørnstad
Kjetil Taskén
Jo Klaveness
Kjell Undheim
Geir Langli
Original Assignee
Solvell As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvell As filed Critical Solvell As
Application granted granted Critical
Publication of DK1765844T3 publication Critical patent/DK1765844T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/213—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids containing cyclic phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK05755520.3T 2004-06-18 2005-06-20 Purin-nukleotidderivater DK1765844T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0413726.1A GB0413726D0 (en) 2004-06-18 2004-06-18 Compounds
PCT/GB2005/002418 WO2005123755A2 (en) 2004-06-18 2005-06-20 Purine nucleotide derivatives

Publications (1)

Publication Number Publication Date
DK1765844T3 true DK1765844T3 (da) 2014-09-01

Family

ID=32750205

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05755520.3T DK1765844T3 (da) 2004-06-18 2005-06-20 Purin-nukleotidderivater

Country Status (10)

Country Link
US (1) US8153609B2 (da)
EP (1) EP1765844B1 (da)
JP (1) JP5044750B2 (da)
CN (1) CN101001865A (da)
AU (1) AU2005254790B2 (da)
CA (1) CA2568907C (da)
DK (1) DK1765844T3 (da)
ES (1) ES2496946T3 (da)
GB (1) GB0413726D0 (da)
WO (1) WO2005123755A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007006544A2 (en) * 2005-07-12 2007-01-18 Vrije Universiteit Brussel Cyclic adenosine monophosphate compounds for the treatment of immune-related disorders
GB0618235D0 (en) * 2006-09-15 2006-10-25 Lauras As Process
LT2448968T (lt) * 2009-06-29 2021-05-10 Bioarctic Ab Antikūnai, atpažįstantys n gale sutrumpintas amiloido protofibriles/oligomerus
NZ607996A (en) 2010-09-22 2014-07-25 Alios Biopharma Inc Substituted nucleotide analogs
CA2819041A1 (en) * 2010-12-22 2012-06-28 Alios Biopharma, Inc. Cyclic nucleotide analogs
CA2860234A1 (en) 2011-12-22 2013-06-27 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
SG10201913554YA (en) 2011-12-22 2020-03-30 Alios Biopharma Inc Substituted nucleosides, nucleotides and analogs thereof
US9441007B2 (en) 2012-03-21 2016-09-13 Alios Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
HK1206362A1 (zh) 2012-03-21 2016-01-08 Alios Biopharma, Inc. 硫代氨基磷酸酯核苷酸前藥的固體形式
USRE48171E1 (en) 2012-03-21 2020-08-25 Janssen Biopharma, Inc. Substituted nucleosides, nucleotides and analogs thereof
WO2013142157A1 (en) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
US20240182511A1 (en) * 2021-04-09 2024-06-06 Merck Sharp & Dohme Llc Novel forms of cyclic dinucleotide compounds
CN117999269A (zh) 2021-09-06 2024-05-07 米雷卡医药有限公司 用于生产环状鸟苷-单磷酸酯类似物的改进方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968101A (en) * 1974-12-20 1976-07-06 Icn Pharmaceuticals, Inc. 8-Substituted cyclic nucleotides by free radical alkylation and acylation
WO1989007108A1 (en) 1988-02-01 1989-08-10 Bernd Jastorff Process for producing nucleoside-3',5'-cyclophosphates and nucleoside-3',5'-cyclothiophosphates
WO1993021929A1 (en) 1992-05-01 1993-11-11 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Phosphorothioate derivatives of cyclic amp analogues
US5625056A (en) * 1992-05-26 1997-04-29 Biolog Life Science Institute Derivatives of cyclic guanosine-3',5'-monophosphorothioate
NO971997D0 (no) 1997-04-29 1997-04-29 Kjetil Tasken Bruk av immunmodulerende midler
JP4902958B2 (ja) * 2002-06-07 2012-03-21 ユニバーシテール・メディッシュ・セントラム・ユトレヒト ｃＡＭＰによって直接活性化される交換タンパク質（Ｅｐａｃ）の活性をモジュレートするための新規な化合物

Also Published As

Publication number Publication date
GB0413726D0 (en) 2004-07-21
CN101001865A (zh) 2007-07-18
ES2496946T3 (es) 2014-09-22
EP1765844A2 (en) 2007-03-28
JP5044750B2 (ja) 2012-10-10
AU2005254790B2 (en) 2012-02-23
EP1765844B1 (en) 2014-07-30
US8153609B2 (en) 2012-04-10
WO2005123755A3 (en) 2006-04-06
JP2008502673A (ja) 2008-01-31
AU2005254790A1 (en) 2005-12-29
US20080293665A1 (en) 2008-11-27
CA2568907C (en) 2015-06-09
CA2568907A1 (en) 2005-12-29
WO2005123755A2 (en) 2005-12-29

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