DK188385A - Fremgangsmaade til paavisning af genetisk materiale - Google Patents
Fremgangsmaade til paavisning af genetisk materiale Download PDFInfo
- Publication number
- DK188385A DK188385A DK188385A DK188385A DK188385A DK 188385 A DK188385 A DK 188385A DK 188385 A DK188385 A DK 188385A DK 188385 A DK188385 A DK 188385A DK 188385 A DK188385 A DK 188385A
- Authority
- DK
- Denmark
- Prior art keywords
- methods
- genetic material
- procedure
- detection
- determining genetic
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60502284A | 1984-04-27 | 1984-04-27 | |
| US65381684A | 1984-09-24 | 1984-09-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK188385D0 DK188385D0 (da) | 1985-04-26 |
| DK188385A true DK188385A (da) | 1985-10-28 |
Family
ID=27084833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK188385A DK188385A (da) | 1984-04-27 | 1985-04-26 | Fremgangsmaade til paavisning af genetisk materiale |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4894325A (de) |
| EP (2) | EP0526912B1 (de) |
| JP (2) | JP2560003B2 (de) |
| AT (2) | ATE91154T1 (de) |
| AU (2) | AU4148685A (de) |
| CA (1) | CA1260372A (de) |
| DE (2) | DE3587427T2 (de) |
| DK (1) | DK188385A (de) |
| ES (1) | ES8609473A1 (de) |
| IL (1) | IL74986A (de) |
| NO (1) | NO165269C (de) |
Families Citing this family (122)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4948882A (en) * | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
| FI71768C (fi) * | 1984-02-17 | 1987-02-09 | Orion Yhtymae Oy | Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning. |
| US6221581B1 (en) * | 1984-04-27 | 2001-04-24 | Enzo Diagnostics, Inc. | Processes for detecting polynucleotides, determining genetic mutations or defects in genetic material, separating or isolating nucleic acid of interest from samples, and useful compositions of matter and multihybrid complex compositions |
| US4820630A (en) * | 1984-11-23 | 1989-04-11 | Digene Diagnostics, Incorporated | Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels |
| CA1272443A (en) * | 1985-02-22 | 1990-08-07 | Nanibhushan Dattagupta | Solution-phase dual hybridization assay for detecting polynucleotide sequences |
| GB8509367D0 (en) * | 1985-04-12 | 1985-05-15 | Amersham Int Plc | Nucleic acid hybridisation |
| US5273882A (en) * | 1985-06-13 | 1993-12-28 | Amgen | Method and kit for performing nucleic acid hybridization assays |
| ES8707343A1 (es) † | 1985-06-13 | 1987-07-16 | Amgen | Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada |
| JP3293820B2 (ja) * | 1985-12-13 | 2002-06-17 | エンゾ− バイオケム インコ−ポレイテツド | 標的ポリヌクレオチドにハイブリツド形成するための新規な一工程方法とポリヌクレオチド化合物 |
| US4882269A (en) * | 1985-12-13 | 1989-11-21 | Princeton University | Amplified hybridization assay |
| FR2601455B1 (fr) * | 1986-07-11 | 1989-08-04 | Stallergenes Lab | Nouveaux reactifs biologiques en phase solide et leur procede d'obtention |
| US5175270A (en) * | 1986-09-10 | 1992-12-29 | Polyprobe, Inc. | Reagents for detecting and assaying nucleic acid sequences |
| AU8103687A (en) * | 1986-10-14 | 1988-05-06 | Beckman Instruments, Inc. | Improved nucleic acid hybridization technique and kit therefor |
| US5714380A (en) | 1986-10-23 | 1998-02-03 | Amoco Corporation | Closed vessel for isolating target molecules and for performing amplification |
| ZA877772B (en) * | 1986-10-23 | 1988-04-20 | Amoco Corporation | Target and background capture methods and apparatus for affinity assays |
| US5750338A (en) * | 1986-10-23 | 1998-05-12 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| IL85551A0 (en) * | 1987-04-01 | 1988-08-31 | Miles Inc | Rapid hybridization assay and reagent system used therein |
| US5124246A (en) * | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
| US5359100A (en) * | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
| AU2735988A (en) * | 1987-12-21 | 1989-07-13 | Amoco Corporation | Target and background capture methods with amplification for affinity assays |
| US5374524A (en) * | 1988-05-10 | 1994-12-20 | E. I. Du Pont De Nemours And Company | Solution sandwich hybridization, capture and detection of amplified nucleic acids |
| EP0405592A3 (en) * | 1989-06-30 | 1991-07-17 | Sanyo Chemical Industries Ltd. | A method for detection of nucleic acid and reagents for their detection |
| US5399676A (en) * | 1989-10-23 | 1995-03-21 | Gilead Sciences | Oligonucleotides with inverted polarity |
| WO1991008307A1 (en) * | 1989-12-04 | 1991-06-13 | Microprobe Corporation | Enhanced capture of target nucleic acid by the use of oligonucleotides covalently attached to polymers |
| US5264343A (en) * | 1990-08-31 | 1993-11-23 | Eleanor Roosevelt Institute | Method for distinguishing normal and cancer cells |
| RU1794088C (ru) * | 1991-03-18 | 1993-02-07 | Институт Молекулярной Биологии Ан@ Ссср | Способ определени нуклеотидной последовательности ДНК и устройство дл его осуществлени |
| WO1993013226A1 (en) * | 1991-12-23 | 1993-07-08 | Chiron Corporation | Hav probes for use in solution phase sandwich hybridization assays |
| US6300058B1 (en) | 1992-01-29 | 2001-10-09 | Hitachi Chemical Research Center, Inc. | Method for measuring messenger RNA |
| CA2128891A1 (en) * | 1992-01-29 | 1993-08-05 | Cylia Keller | Polynucleotide immobilized support |
| US5329461A (en) * | 1992-07-23 | 1994-07-12 | Acrogen, Inc. | Digital analyte detection system |
| WO1994002636A1 (en) * | 1992-07-28 | 1994-02-03 | Hitachi Chemical Company Ltd. | Gene detection system |
| US5580971A (en) * | 1992-07-28 | 1996-12-03 | Hitachi Chemical Company, Ltd. | Fungal detection system based on rRNA probes |
| US7713528B1 (en) | 1993-02-18 | 2010-05-11 | Enzo Therapeutics, Inc. | Method for in vivo delivery of active compounds using reagent conjugate |
| DE69434809T2 (de) * | 1993-05-28 | 2007-03-29 | The Mount Sinai School Of Medicine Of New York University | Bc200 rna, daraus abgeleitete proben und entsprechende anwendungen |
| FR2707010B1 (de) * | 1993-06-25 | 1995-09-29 | Bio Merieux | |
| RU2041261C1 (ru) * | 1993-08-11 | 1995-08-09 | Институт молекулярной биологии им.В.А.Энгельгардта РАН | Способ изготовления матрицы для детектирования мисматчей |
| FR2710075B1 (fr) * | 1993-09-15 | 1995-10-27 | Bio Merieux | Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal. |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5952172A (en) | 1993-12-10 | 1999-09-14 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US5824473A (en) | 1993-12-10 | 1998-10-20 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
| CA2140081C (en) | 1994-01-13 | 2008-04-01 | Dean L. Engelhardt | Process, construct and conjugate for producing multiple nucleic acid copies |
| US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
| US5731153A (en) * | 1996-08-26 | 1998-03-24 | The Regents Of The University Of California | Identification of random nucleic acid sequence aberrations using dual capture probes which hybridize to different chromosome regions |
| US5783387A (en) * | 1995-02-06 | 1998-07-21 | The Regents Of The University Of California | Method for identifying and quantifying nucleic acid sequence aberrations |
| US5853974A (en) * | 1995-06-07 | 1998-12-29 | Chiron Corporation | Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates |
| US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
| US5780227A (en) * | 1995-06-07 | 1998-07-14 | Sheridan; Patrick J. | Oligonucleotide probe conjugated to a purified hydrophilic alkaline phosphatase and uses thereof |
| US6096508A (en) * | 1995-08-16 | 2000-08-01 | Kirkegaard & Perry Laboratoies, Inc. | Method of reducing background in biotin-based assays |
| US7282327B2 (en) | 1996-01-23 | 2007-10-16 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| US6965020B2 (en) | 1996-01-23 | 2005-11-15 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| EP0880598A4 (de) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | Verfahren zur analyse von nukleinsäure |
| US7291463B2 (en) | 1996-01-23 | 2007-11-06 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| US20010018514A1 (en) | 1998-07-31 | 2001-08-30 | Mcgall Glenn H. | Nucleic acid labeling compounds |
| US7423143B2 (en) | 1996-01-23 | 2008-09-09 | Affymetrix. Inc. | Nucleic acid labeling compounds |
| US6864059B2 (en) | 1996-01-23 | 2005-03-08 | Affymetrix, Inc. | Biotin containing C-glycoside nucleic acid labeling compounds |
| JP3545158B2 (ja) * | 1996-03-14 | 2004-07-21 | シスメックス株式会社 | 遺伝子検出法 |
| FR2746413B1 (fr) * | 1996-03-19 | 1998-04-24 | Bio Merieux | Detection d'une sequence nucleotidique avec amplification de signal |
| US6444423B1 (en) | 1996-06-07 | 2002-09-03 | Molecular Dynamics, Inc. | Nucleosides comprising polydentate ligands |
| WO1998004740A1 (en) * | 1996-07-29 | 1998-02-05 | Nanosphere Llc | Nanoparticles having oligonucleotides attached thereto and uses therefor |
| US6582921B2 (en) | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
| US5853993A (en) * | 1996-10-21 | 1998-12-29 | Hewlett-Packard Company | Signal enhancement method and kit |
| US6096273A (en) | 1996-11-05 | 2000-08-01 | Clinical Micro Sensors | Electrodes linked via conductive oligomers to nucleic acids |
| US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
| US7393645B2 (en) * | 1996-11-05 | 2008-07-01 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| US7014992B1 (en) * | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
| US7045285B1 (en) * | 1996-11-05 | 2006-05-16 | Clinical Micro Sensors, Inc. | Electronic transfer moieties attached to peptide nucleic acids |
| US7160678B1 (en) | 1996-11-05 | 2007-01-09 | Clinical Micro Sensors, Inc. | Compositions for the electronic detection of analytes utilizing monolayers |
| ES2271994T3 (es) * | 1997-05-02 | 2007-04-16 | Gen-Probe Incorporated | Hibridacion en dos pasos y captura de un polinucleotido. |
| US6534273B2 (en) | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| US6013459A (en) * | 1997-06-12 | 2000-01-11 | Clinical Micro Sensors, Inc. | Detection of analytes using reorganization energy |
| BR9814271A (pt) * | 1997-12-12 | 2001-03-20 | Digene Corp | Determinação de doenças relacionadas com o vìrus do papiloma humano |
| EP1049803A4 (de) * | 1997-12-15 | 2002-08-21 | Nexstar Pharmaceuticals Inc | Gleichmässige erkennung von zielmolekül durch nukleinsäure ligand - beacon ligand interaktion |
| US20030219803A1 (en) * | 1997-12-15 | 2003-11-27 | Somalogic, Incorporated | Homogeneous detection of a target through nucleic acid ligand-ligand beacon interaction |
| US6686150B1 (en) | 1998-01-27 | 2004-02-03 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| WO1999037819A2 (en) | 1998-01-27 | 1999-07-29 | Clinical Micro Sensors, Inc. | Amplification of nucleic acids with electronic detection |
| US20050244954A1 (en) * | 1998-06-23 | 2005-11-03 | Blackburn Gary F | Binding acceleration techniques for the detection of analytes |
| US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
| US6290839B1 (en) | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
| US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
| US6740518B1 (en) * | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
| AU1241000A (en) * | 1998-10-27 | 2000-05-15 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
| JP3267576B2 (ja) * | 1998-11-09 | 2002-03-18 | 三光純薬株式会社 | プローブ高分子の形成方法 |
| US6833267B1 (en) | 1998-12-30 | 2004-12-21 | Clinical Micro Sensors, Inc. | Tissue collection devices containing biosensors |
| US6942771B1 (en) | 1999-04-21 | 2005-09-13 | Clinical Micro Sensors, Inc. | Microfluidic systems in the electrochemical detection of target analytes |
| US7312087B2 (en) | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
| US20020177135A1 (en) * | 1999-07-27 | 2002-11-28 | Doung Hau H. | Devices and methods for biochip multiplexing |
| ATE417127T1 (de) | 1999-07-26 | 2008-12-15 | Clinical Micro Sensors Inc | Nukelinsäuresequenzbestimmung mittels elektronischem nachweis |
| US6428957B1 (en) | 1999-11-08 | 2002-08-06 | Agilent Technologies, Inc. | Systems tools and methods of assaying biological materials using spatially-addressable arrays |
| AU2001241939A1 (en) * | 2000-02-28 | 2001-09-12 | Maxygen, Inc. | Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation |
| ES2317893T3 (es) * | 2000-03-31 | 2009-05-01 | Sanko Junyaku Co., Ltd. | Sondas para construir polimeros de sondas, procedimiento para construir un polimero de sondas y uso del mismo. |
| US6753143B2 (en) | 2000-05-01 | 2004-06-22 | Clinical Micro Sensors, Inc. | Target analyte detection using asymmetrical self-assembled monolayers |
| US7601497B2 (en) * | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
| US7439016B1 (en) * | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
| JP4382265B2 (ja) * | 2000-07-12 | 2009-12-09 | 日本電気株式会社 | 酸化シリコン膜の形成方法及びその形成装置 |
| CA2440615A1 (en) | 2001-03-12 | 2002-09-19 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| DE10164197A1 (de) * | 2001-04-12 | 2003-07-17 | Vladimir M Mirsky | Steuerbare Verstärkung der Empfindlichkeit beim Hybridisierungsnachweis |
| US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
| US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
| US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
| US20040011650A1 (en) * | 2002-07-22 | 2004-01-22 | Frederic Zenhausern | Method and apparatus for manipulating polarizable analytes via dielectrophoresis |
| US9303262B2 (en) * | 2002-09-17 | 2016-04-05 | Archemix Llc | Methods for identifying aptamer regulators |
| DK1778867T3 (da) | 2004-07-01 | 2010-08-02 | Gen Probe Inc | Fremgangsmåder og sammensætninger til detektering af nucleinsyrer i en biologisk prøve |
| EP1871913A2 (de) * | 2005-03-25 | 2008-01-02 | Ambion, Inc. | Verfahren und zusammensetzungen zur verringerung abundanter rna-transkripte |
| CA2584230C (en) | 2005-05-06 | 2012-11-27 | Gen-Probe Incorporated | Methods of nucleic acid target capture |
| US20090162845A1 (en) * | 2007-12-20 | 2009-06-25 | Elazar Rabbani | Affinity tag nucleic acid and protein compositions, and processes for using same |
| WO2009140374A2 (en) | 2008-05-13 | 2009-11-19 | Gen-Probe Incorporated | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
| TWI417389B (zh) * | 2008-10-27 | 2013-12-01 | Qiagen Gaithersburg Inc | 於自動平台上之快速結果雜交捕捉法 |
| WO2010068473A1 (en) * | 2008-11-25 | 2010-06-17 | Gen-Probe Incorporated | Compositions and methods for detecting small rnas, and uses thereof |
| EP2385979B1 (de) * | 2009-01-28 | 2017-08-16 | QIAGEN Gaithersburg, Inc. | Sequenzspezifisches verfahren zur vorbereitung grossvolumiger proben und assay |
| AU2010242867B2 (en) * | 2009-05-01 | 2016-05-12 | Qiagen Gaithersburg, Inc. | A non-target amplification method for detection of RNA splice-forms in a sample |
| US20110053143A1 (en) * | 2009-09-03 | 2011-03-03 | Qiagen Gaithersburg Inc. | Methods and kits for determining viral load in clinical samples |
| JP5826752B2 (ja) * | 2009-09-14 | 2015-12-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 細胞学用培地に固定された組織サンプルから核酸またはタンパク質を回収するための組成物および方法 |
| EP2521778B1 (de) | 2010-01-04 | 2014-03-19 | QIAGEN Gaithersburg, Inc. | Verfahren, zusammensetzungen und kits zur gewinnung von nukleinsäuren oder proteinen aus festen gewebeproben |
| ES2615728T3 (es) * | 2010-01-29 | 2017-06-08 | Qiagen Gaithersburg, Inc. | Métodos y composiciones para una purificación y un análisis múltiple específico de secuencia de ácidos nucleicos |
| CA2787781A1 (en) | 2010-01-29 | 2011-08-04 | Qiagen Gaithersburg, Inc. | Method of determining and confirming the presence of an hpv in a sample |
| US9422593B2 (en) | 2010-05-19 | 2016-08-23 | Qiagen Gaithresburg, Inc | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
| CA2799205A1 (en) | 2010-05-25 | 2011-12-01 | Qiagen Gaithersburg, Inc. | Fast results hybrid capture assay and associated strategically-truncated probes |
| AU2012220575B2 (en) | 2011-02-24 | 2017-01-12 | Qiagen Gaithersburg, Inc. | Materials and methods for detection of HPV nucleic acid |
| KR102275006B1 (ko) | 2013-03-11 | 2021-07-09 | 메소 스케일 테크놀러지즈, 엘엘시 | 다중화 어세이를 수행하기 위한 개선된 방법 |
| EP3356547B1 (de) * | 2015-10-01 | 2020-11-18 | Dynamic Biosensors GmbH | Verfahren zur detektion von molekularen wechselwirkungen unter verwendung einer immobilisierten nukleinsäure |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
| US4376165A (en) * | 1978-06-22 | 1983-03-08 | Miles Laboratories, Inc. | Method of preparing an enzyme-labeled ligand for use in specific binding assays and the labeled conjugate produced thereby |
| GB2027031A (en) * | 1978-08-02 | 1980-02-13 | Hoffmann La Roche | Diagnostic Reagent Comprising a Proteinaceous Material Bonded to a Latex |
| US4334017A (en) * | 1979-04-16 | 1982-06-08 | Massachusetts Institute Of Technology | Method for detecting cancer in mammalian tissue |
| US4510244A (en) * | 1980-04-17 | 1985-04-09 | The Board Of Trustees Of The Leland Stanford Jr. University | Cell labeling with antigen-coupled microspheres |
| US4376110A (en) * | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| CA1190838A (en) * | 1981-07-17 | 1985-07-23 | Cavit Akin | Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer |
| JPS5840099A (ja) * | 1981-07-17 | 1983-03-08 | アモコ・コ−ポレ−ション | 光−放射ポリヌクレオチドの交雑診断方法 |
| CA1180647A (en) * | 1981-07-17 | 1985-01-08 | Cavit Akin | Light-emitting polynucleotide hybridization diagnostic method |
| FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| CA1223831A (en) * | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| US4554088A (en) * | 1983-05-12 | 1985-11-19 | Advanced Magnetics Inc. | Magnetic particles for use in separations |
| CA1222680A (en) * | 1983-07-05 | 1987-06-09 | Nanibhushan Dattagupta | Testing dna samples for particular nucleotide sequences |
| CA1256005A (en) * | 1983-09-26 | 1989-06-20 | W. Peter Hansen | Sandwich hybridization method for nucleic acid detection |
| GB8331071D0 (en) * | 1983-11-22 | 1983-12-29 | Karayiannis P | Assay for dna/rna |
| US4724202A (en) * | 1983-12-12 | 1988-02-09 | Molecular Diagnostics, Inc. | Use of non-hybridizable nucleic acids for the detection of nucleic acid hybridization |
| US4699876A (en) * | 1984-01-27 | 1987-10-13 | E. I. Du Pont De Nemours And Company | Nonradiometric polynucleotide probes |
| FI71768C (fi) * | 1984-02-17 | 1987-02-09 | Orion Yhtymae Oy | Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning. |
| US4749647A (en) * | 1984-06-22 | 1988-06-07 | Genetic Systems Corporation | Polymerization-induced separation assay using recognition pairs |
| US4755458A (en) * | 1984-08-30 | 1988-07-05 | Enzo Biochem, Inc. | Composition and method for the detection of the presence of a polynucleotide sequence of interest |
| US4563417A (en) * | 1984-08-31 | 1986-01-07 | Miles Laboratories, Inc. | Nucleic acid hybridization assay employing antibodies to intercalation complexes |
-
1985
- 1985-04-17 CA CA000479415A patent/CA1260372A/en not_active Expired
- 1985-04-22 AU AU41486/85A patent/AU4148685A/en not_active Abandoned
- 1985-04-23 IL IL74986A patent/IL74986A/xx unknown
- 1985-04-26 EP EP92117826A patent/EP0526912B1/de not_active Expired - Lifetime
- 1985-04-26 EP EP85105130A patent/EP0159719B1/de not_active Expired - Lifetime
- 1985-04-26 NO NO851689A patent/NO165269C/no unknown
- 1985-04-26 DE DE85105130T patent/DE3587427T2/de not_active Expired - Lifetime
- 1985-04-26 DE DE3588250T patent/DE3588250D1/de not_active Expired - Lifetime
- 1985-04-26 DK DK188385A patent/DK188385A/da not_active Application Discontinuation
- 1985-04-26 ES ES542602A patent/ES8609473A1/es not_active Expired
- 1985-04-26 JP JP60089104A patent/JP2560003B2/ja not_active Expired - Lifetime
- 1985-04-26 AT AT85105130T patent/ATE91154T1/de not_active IP Right Cessation
- 1985-04-26 AT AT92117826T patent/ATE258230T1/de not_active IP Right Cessation
-
1987
- 1987-01-15 US US07/005,327 patent/US4894325A/en not_active Expired - Lifetime
-
1989
- 1989-12-07 AU AU45984/89A patent/AU4598489A/en not_active Abandoned
-
1996
- 1996-03-15 JP JP8059476A patent/JP2735822B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES542602A0 (es) | 1986-09-01 |
| DE3587427D1 (de) | 1993-08-05 |
| EP0159719B1 (de) | 1993-06-30 |
| US4894325A (en) | 1990-01-16 |
| DE3587427T2 (de) | 1994-01-20 |
| EP0526912A2 (de) | 1993-02-10 |
| ES8609473A1 (es) | 1986-09-01 |
| JPS60237361A (ja) | 1985-11-26 |
| AU4598489A (en) | 1990-03-29 |
| DE3588250D1 (de) | 2004-02-26 |
| IL74986A (en) | 1990-08-31 |
| NO165269C (no) | 1991-01-16 |
| NO165269B (no) | 1990-10-08 |
| AU4148685A (en) | 1986-01-30 |
| EP0159719A3 (en) | 1988-03-30 |
| IL74986A0 (en) | 1985-08-30 |
| EP0159719A2 (de) | 1985-10-30 |
| JP2560003B2 (ja) | 1996-12-04 |
| DK188385D0 (da) | 1985-04-26 |
| EP0526912A3 (de) | 1994-03-02 |
| JP2735822B2 (ja) | 1998-04-02 |
| CA1260372A (en) | 1989-09-26 |
| JPH08336400A (ja) | 1996-12-24 |
| ATE91154T1 (de) | 1993-07-15 |
| EP0526912B1 (de) | 2004-01-21 |
| NO851689L (no) | 1985-10-28 |
| ATE258230T1 (de) | 2004-02-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK188385D0 (da) | Fremgangsmaade til paavisning af genetisk materiale | |
| EP0085115A4 (de) | Modifizierte blockkopolymer-zusammensetzungen. | |
| FI864964A7 (fi) | Nukleiinihappojaksojen määrittämiseen soveltuvia molekyylejä. | |
| DK375283D0 (da) | Dna-sekvenser, rekombinations-dna-molekyler samt fremgangsmader til fremstilling af kvaegvaeksthormonlignende polypeptider | |
| DK121685D0 (da) | Fremgangsmaade til maerkning af nukleinsyrer og middel til anvendelse af fremgangsmaaden | |
| DK73483A (da) | Dna-sekvenser, rekombinant-dna-molekyler samt fremgangsmaader til fremstilling af human-immune interferonlignende polypeptider | |
| DK110885A (da) | Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf | |
| DE3587864D1 (de) | Rekombinant-dns-moleküle. | |
| DE3587549D1 (de) | Ergänzungstestverfahren von proteine bindenden enzymen. | |
| MX9203519A (es) | Metodo de recombinacion para la produccion de inhibidores de proteasa de serina y secuencias de adn utiles para los mismos. | |
| DE3576524D1 (de) | Dna-sequenzen. | |
| PT1025245E (pt) | Criacao rapida de linhas celulares estaveis de mamifero produzindo elevados iiveis de proteinas recombinantes | |
| ATE186575T1 (de) | Verfahren zur identifizierung von menschlichen und tierischen zellen mit der fähigkeit zu unbegrenzter proliferation oder zur tumorbildung | |
| DK129085A (da) | Fremgangsmaade til fremstilling af proteiner | |
| IT8521311A0 (it) | Fosforo rosso stabilizzato e veicolato come antifiamma di polimeri. | |
| DE3689372D1 (de) | Vernetzungsverfahren organopolysilaner polymere. | |
| FI844213A7 (fi) | Menetelmä DNA:n tai DNA-fragmentin emässekvenssin määrittämiseksi käyttäen autoradiografiaa. | |
| WO2000031253A3 (fr) | Mutations du gene de la parkine, compositions, methodes et utilisations | |
| DE3581559D1 (de) | Fluorierte polymere enthaltendes optisches material. | |
| DK577283A (da) | Gen kodet for interleukin-2-polypeptid, rekombinant dna baerende dette gen, levende cellelinie indeholdende dette rekombinante dna og fremgangsmaade til fremstilling af interleukin-2 ved anvendelse af denne cellelinie | |
| FR2571864B2 (fr) | Appareil de visee comportant une voie ecartometrique. | |
| FR2568381B1 (fr) | Appareil de visee comportant une voie ecartometrique | |
| DK0868535T3 (da) | Fremgangsmåder og sammensætninger til bestemmelse af sekvensen for nukleinsyremolekyler | |
| ATE98701T1 (de) | Verfahren zur durchfuehrung von hybridisierungstests von nukleinsaeuren. | |
| IT8485664A0 (it) | Procedimento per il trattamento di liquami di conceria con ricupero di torbide proteiche utilizzabili in zootecnia. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |