DK1896439T3 - Krystallinsk base af escitalopram og orodispergerbare tabletter, der omfatter escitaloprambase - Google Patents

Krystallinsk base af escitalopram og orodispergerbare tabletter, der omfatter escitaloprambase

Info

Publication number: DK1896439T3
Authority: DK; Denmark
Prior art keywords: escitalopram; base; crystalline; orodispersible tablets; orodispersible
Prior art date: 2005-06-22

Application number

DK06742481.2T

Other languages

English (en)

Other versions

DK1896439T4 (da

Inventor

Hans Petersen

Ole Nielsen

Michael Harold Rock

Robert Dancer

Helle Eliasen

Ken Liljegren

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-06-22

Filing date

2006-06-22

Publication date

2011-02-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37546630&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1896439(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-06-22 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2011-02-28 Publication of DK1896439T3 publication Critical patent/DK1896439T3/da

2015-01-12 Application granted granted Critical

2015-01-12 Publication of DK1896439T4 publication Critical patent/DK1896439T4/da

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Emergency Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK06742481.2T 2005-06-22 2006-06-22 Krystallinsk base af escitalopram og orodispergerbare tabletter, der omfatter escitaloprambase DK1896439T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200500912		2005-06-22
PCT/DK2006/000366 WO2006136169A2 (en)	2005-06-22	2006-06-22	Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Publications (2)

Publication Number	Publication Date
DK1896439T3 true DK1896439T3 (da)	2011-02-28
DK1896439T4 DK1896439T4 (da)	2015-01-12

Family

ID=37546630

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK06742481.2T DK1896439T4 (da)	2005-06-22	2006-06-22	Krystallinsk base af escitalopram og orodispergerbare tabletter, der omfatter escitaloprambase
DK200800075A DK200800075A (da)	2005-06-22	2008-01-21	Krystallinsk base af escitalopram og orodispergerbare tabletter indeholdende escitaloprambase
DKPA200900284A DK200900284A (da)	2005-06-22	2009-02-27	Krystallinsk base af escitalopram og smeltetabletter indeholdende escitalopram base

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DK200800075A DK200800075A (da)	2005-06-22	2008-01-21	Krystallinsk base af escitalopram og orodispergerbare tabletter indeholdende escitaloprambase
DKPA200900284A DK200900284A (da)	2005-06-22	2009-02-27	Krystallinsk base af escitalopram og smeltetabletter indeholdende escitalopram base

Country Status (39)

Country	Link
EP (3)	EP2385044A1 (da)
JP (5)	JP4906852B2 (da)
KR (5)	KR20080018191A (da)
CN (2)	CN101928269A (da)
AR (2)	AR055062A1 (da)
AT (3)	AT10983U1 (da)
AU (2)	AU2006261452B2 (da)
BG (1)	BG66086B1 (da)
BR (1)	BRPI0612295A2 (da)
CA (2)	CA2646780A1 (da)
CY (1)	CY1112392T1 (da)
CZ (3)	CZ301286B6 (da)
DE (2)	DE602006019961D1 (da)
DK (3)	DK1896439T4 (da)
EA (2)	EA201001108A1 (da)
EE (1)	EE00773U1 (da)
ES (2)	ES2319073B1 (da)
FI (2)	FI20080548L (da)
GB (2)	GB2442160B (da)
HR (1)	HRP20110093T4 (da)
HU (1)	HUP0800135A3 (da)
IL (1)	IL187454A0 (da)
IS (1)	IS8705A (da)
LT (1)	LT5550B (da)
LV (1)	LV13677B (da)
MX (1)	MX2007015328A (da)
MY (2)	MY143239A (da)
NO (2)	NO20080359L (da)
PL (2)	PL384185A1 (da)
PT (1)	PT1896439E (da)
RS (1)	RS51575B2 (da)
SG (1)	SG169358A1 (da)
SI (1)	SI1896439T2 (da)
SK (1)	SK500402007A3 (da)
TR (2)	TR200708792T1 (da)
TW (2)	TWI347942B (da)
UA (1)	UA86536C2 (da)
WO (1)	WO2006136169A2 (da)
ZA (2)	ZA200711066B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0123400D0 (en)	2001-09-28	2001-11-21	Novartis Ag	Organic compounds
WO2008059514A2 (en) *	2006-07-31	2008-05-22	Cadila Healthcare Limited	Process for preparing escitalopram
EP2134325A2 (en) *	2007-03-01	2009-12-23	Aurobindo Pharma Limited	Stable solid dosage forms of an antidepressant
DK2595979T3 (da)	2010-07-23	2016-05-17	Lundbeck & Co As H	Fremgangsmåde til oprensningen af farmaceutisk acceptable salte af escitalopram
CN103360353A (zh) *	2013-08-07	2013-10-23	中国药科大学	草酸艾司西酞普兰杂质的制备方法
JP2018016569A (ja) *	2016-07-26	2018-02-01	株式会社トクヤマ	（１ｓ）−１−［３−（ジメチルアミノ）プロピル］−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフラン−５−カルボニトリル蓚酸塩の製造方法
WO2018190294A1 (ja) *	2017-04-10	2018-10-18	東和薬品株式会社	エスシタロプラム医薬組成物
CN110711198B (zh) *	2018-07-12	2022-03-15	山东大学	D-甘露糖在制备抗抑郁药物中的应用
KR102331187B1 (ko)	2019-04-09	2021-11-26	주식회사 라이트팜텍	에스시탈로프람을 함유하는 안정성이 우수한 경구용 액제 조성물 및 그의 제조방법
WO2022153262A1 (en) *	2021-01-18	2022-07-21	Anton Frenkel	Pharmaceutical dosage form

Family Cites Families (39)

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GB1526331A (en)	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
JPH05222041A (ja) *	1992-02-13	1993-08-31	Mitsubishi Gas Chem Co Inc	アデニン誘導体の精製法
FI962989A0 (fi) *	1994-01-27	1996-07-26	Univ Oklahoma	Nopeasti liukeneva oraalinen annosmuoto
US5607697A (en) *	1995-06-07	1997-03-04	Cima Labs, Incorporated	Taste masking microparticles for oral dosage forms
EP0993524B1 (en)	1997-06-30	2002-11-20	Beloit Technologies, Inc.	Method and apparatus for the high speed application of coating to a traveling paper web
TR200000066T2 (tr)	1997-07-08	2000-11-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem.
ES2149734T3 (es)	1997-11-11	2003-02-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
FR2785538B1 (fr) *	1998-11-06	2004-04-09	Prographarm Laboratoires	Comprime a delitement rapide perfectionne
US20020071864A1 (en) *	1999-03-25	2002-06-13	Yuhan Corporation	Rapidly disintegrable tablet for oral administration
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
JP2001226372A (ja) *	1999-12-06	2001-08-21	Sumika Fine Chemicals Co Ltd	ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
GB2357762B (en) *	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
US7510728B2 (en) *	2000-10-06	2009-03-31	Takeda Pharmaceutical Company Limited	Solid preparations
CN1469737A (zh) *	2000-10-16	2004-01-21	��һ��ҩ��ʽ��	口腔内快速崩解的药用组合物及其制备方法
US7799342B2 (en)	2000-12-06	2010-09-21	Wyeth Llc	Fast dissolving tablet
JP3798982B2 (ja) *	2000-12-22	2006-07-19	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法
CA2359810C (en) *	2000-12-28	2002-11-05	H. Lundbeck A/S	Process for the preparation of pure citalopram
EA200301195A1 (ru) *	2001-05-01	2004-04-29	Х. Лундбекк А/С	Применение энантиомерно чистого эсциталопрама
US6872405B2 (en) *	2001-05-10	2005-03-29	Yamanouchi Pharmaceutical Co., Ltd.	Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
GB0113842D0 (en) *	2001-06-07	2001-08-01	Boots Co Plc	Therapeutic agents
AR034612A1 (es) *	2001-06-25	2004-03-03	Lundbeck & Co As H	Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es)	2001-07-13	2004-03-17	Lundbeck & Co As H	Metodo para la preparacion de escitalopram
HRP20031073A2 (en) *	2001-07-31	2004-04-30	Lundbeck & Co As H	Crystalline composition containing escitalopram
IS7239A (is)	2001-12-14	2004-04-29	H. Lundbeck A/S	Aðferð til framleiðslu á essítalóprami
WO2003057132A2 (en) *	2002-01-07	2003-07-17	Sun Pharmaceutical Industries Limited	Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
FR2834889B1 (fr) *	2002-01-18	2004-04-02	Roquette Freres	Forme pharmaceutique solide orodispersible
GB0204607D0 (en) *	2002-02-27	2002-04-10	Matrix Lab Ltd	Process
EP1517676A1 (en) *	2002-05-03	2005-03-30	Skyepharma Canada Inc.	Oral dosage forms comprising fenofibrate
CN100349885C (zh)	2002-12-23	2007-11-21	H·隆德贝克有限公司	依他普仑氢溴酸盐及其制备方法
CN1510024A (zh) *	2002-12-24	2004-07-07	北京德众万全药物技术开发有限公司	可用于制备西酞普兰(s)-对映异构体的新的化合物及其制备方法
DE10305984A1 (de) *	2003-02-13	2004-09-02	Helm Ag	Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen
CN1819819B (zh) *	2003-05-07	2011-03-09	株式会社三养社	用于制备速熔片的高度可塑性颗粒
KR101159617B1 (ko) *	2003-10-15	2012-06-27	후지카가쿠고교가부시키가이샤	구강내 속붕해성 정제
AU2003282383A1 (en) *	2003-11-20	2005-06-08	Natco Pharma Limited	A process for the preparation of high purity escitalopram
HU227491B1 (en) *	2003-11-25	2011-07-28	Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag	Tablet containing citalopram hydrogen bromide
BRPI0508266A (pt) *	2004-03-05	2007-07-31	Lundbeck & Co As H	partìculas cristalinas de oxalato de escitalopram, forma de dosagem única sólida, e, métodos para a fabricação de partìculas cristalinas de oxalato de escitalopram e para reduzir a quantidade de hidroxila que contém impurezas no citalopram, escitalopram ou uma mistura não racêmica de r- e s-citalopram
EP1877394A1 (en) *	2005-04-04	2008-01-16	Jubilant Organosys Limited	Process for the preparation of escitalopram or its acid addition salts

2006
- 2006-06-15 TW TW095121358A patent/TWI347942B/zh not_active IP Right Cessation
- 2006-06-15 TW TW100102601A patent/TWI358407B/zh not_active IP Right Cessation
- 2006-06-21 MY MYPI2010000618A patent/MY143239A/en unknown
- 2006-06-21 MY MYPI20062933A patent/MY143252A/en unknown
- 2006-06-21 AR ARP060102654A patent/AR055062A1/es not_active Application Discontinuation
- 2006-06-22 HU HU0800135A patent/HUP0800135A3/hu unknown
- 2006-06-22 WO PCT/DK2006/000366 patent/WO2006136169A2/en not_active Ceased
- 2006-06-22 DK DK06742481.2T patent/DK1896439T4/da active
- 2006-06-22 TR TR2007/08792T patent/TR200708792T1/xx unknown
- 2006-06-22 CN CN201010286088XA patent/CN101928269A/zh active Pending
- 2006-06-22 PL PL384185A patent/PL384185A1/pl unknown
- 2006-06-22 KR KR1020077028918A patent/KR20080018191A/ko not_active Ceased
- 2006-06-22 CA CA002646780A patent/CA2646780A1/en not_active Abandoned
- 2006-06-22 BR BRPI0612295-7A patent/BRPI0612295A2/pt not_active IP Right Cessation
- 2006-06-22 EP EP10179318A patent/EP2385044A1/en not_active Withdrawn
- 2006-06-22 CA CA2612827A patent/CA2612827C/en not_active Expired - Fee Related
- 2006-06-22 GB GB0724557A patent/GB2442160B/en not_active Expired - Fee Related
- 2006-06-22 PT PT06742481T patent/PT1896439E/pt unknown
- 2006-06-22 CZ CZ20080429A patent/CZ301286B6/cs not_active IP Right Cessation
- 2006-06-22 CZ CZ20070898A patent/CZ299906B6/cs not_active IP Right Cessation
- 2006-06-22 AT AT0900506U patent/AT10983U1/de not_active IP Right Cessation
- 2006-06-22 DE DE602006019961T patent/DE602006019961D1/de active Active
- 2006-06-22 GB GB0811164A patent/GB2448834B/en not_active Expired - Fee Related
- 2006-06-22 KR KR1020117015711A patent/KR20110084341A/ko not_active Ceased
- 2006-06-22 ES ES200750085A patent/ES2319073B1/es not_active Expired - Fee Related
- 2006-06-22 RS RS20110057A patent/RS51575B2/sr unknown
- 2006-06-22 KR KR1020107026804A patent/KR20100133023A/ko not_active Ceased
- 2006-06-22 FI FI20080548A patent/FI20080548L/fi unknown
- 2006-06-22 AT AT06742481T patent/ATE497500T1/de active
- 2006-06-22 HR HRP20110093TT patent/HRP20110093T4/hr unknown
- 2006-06-22 EA EA201001108A patent/EA201001108A1/ru unknown
- 2006-06-22 SI SI200630923T patent/SI1896439T2/sl unknown
- 2006-06-22 CZ CZ20080430A patent/CZ300686B6/cs not_active IP Right Cessation
- 2006-06-22 EP EP10179395A patent/EP2325177A1/en not_active Withdrawn
- 2006-06-22 UA UAA200800362A patent/UA86536C2/ru unknown
- 2006-06-22 FI FI20077133A patent/FI20077133A7/fi unknown
- 2006-06-22 EA EA200800102A patent/EA019239B1/ru not_active IP Right Cessation
- 2006-06-22 PL PL06742481T patent/PL1896439T5/pl unknown
- 2006-06-22 CN CNA2006800200393A patent/CN101189220A/zh active Pending
- 2006-06-22 KR KR1020127014205A patent/KR20120064140A/ko not_active Ceased
- 2006-06-22 MX MX2007015328A patent/MX2007015328A/es active IP Right Grant
- 2006-06-22 ES ES06742481.2T patent/ES2356838T5/es active Active
- 2006-06-22 TR TR2010/00625T patent/TR201000625T1/xx unknown
- 2006-06-22 SG SG201100648-3A patent/SG169358A1/en unknown
- 2006-06-22 EE EEU200800003U patent/EE00773U1/xx not_active IP Right Cessation
- 2006-06-22 KR KR1020117005777A patent/KR101340815B1/ko active Active
- 2006-06-22 AU AU2006261452A patent/AU2006261452B2/en not_active Withdrawn - After Issue
- 2006-06-22 JP JP2008517323A patent/JP4906852B2/ja active Active
- 2006-06-22 EP EP06742481.2A patent/EP1896439B2/en active Active
- 2006-06-22 ZA ZA200711066A patent/ZA200711066B/xx unknown
- 2006-06-22 DE DE112006001619T patent/DE112006001619T5/de not_active Withdrawn
- 2006-06-22 SK SK50040-2007A patent/SK500402007A3/sk unknown
2007
- 2007-11-18 IL IL187454A patent/IL187454A0/en unknown
- 2007-12-19 BG BG10110024A patent/BG66086B1/bg unknown
- 2007-12-21 LV LVP-07-157A patent/LV13677B/lv unknown
2008
- 2008-01-14 IS IS8705A patent/IS8705A/is unknown
- 2008-01-18 NO NO20080359A patent/NO20080359L/no unknown
- 2008-01-21 DK DK200800075A patent/DK200800075A/da not_active Application Discontinuation
- 2008-01-21 LT LT2008005A patent/LT5550B/lt not_active IP Right Cessation
- 2008-10-07 JP JP2008260742A patent/JP4415056B2/ja active Active
2009
- 2009-02-27 DK DKPA200900284A patent/DK200900284A/da not_active Application Discontinuation
- 2009-03-10 ZA ZA200901698A patent/ZA200901698B/en unknown
- 2009-05-12 JP JP2009115279A patent/JP2009179634A/ja active Pending
- 2009-05-12 JP JP2009115280A patent/JP2009179635A/ja active Pending
- 2009-07-07 AT AT0041709U patent/AT11883U1/de not_active IP Right Cessation
2010
- 2010-03-05 AU AU2010200844A patent/AU2010200844A1/en not_active Withdrawn
- 2010-12-20 NO NO20101777A patent/NO20101777L/no not_active Application Discontinuation
- 2010-12-27 AR ARP100104958A patent/AR079750A2/es not_active Application Discontinuation
2011
- 2011-02-03 CY CY20111100116T patent/CY1112392T1/el unknown
- 2011-11-24 JP JP2011255804A patent/JP5731957B2/ja active Active

Also Published As

Publication number	Publication date
EA019239B1 (ru)	2014-02-28
AT11883U1 (de)	2011-06-15
EP1896439A2 (en)	2008-03-12
GB2442160A (en)	2008-03-26
PT1896439E (pt)	2011-02-15
TW200740785A (en)	2007-11-01
JP4906852B2 (ja)	2012-03-28
CA2612827A1 (en)	2006-12-28
BG66086B1 (bg)	2011-03-31
JP2009046506A (ja)	2009-03-05
NO20080359L (no)	2008-01-18
KR20120064140A (ko)	2012-06-18
GB2442160B (en)	2010-01-20
JP5731957B2 (ja)	2015-06-10
GB0811164D0 (en)	2008-07-23
SG169358A1 (en)	2011-03-30
ES2356838T3 (es)	2011-04-13
AU2010200844A1 (en)	2010-04-01
MX2007015328A (es)	2008-02-15
TWI358407B (en)	2012-02-21
GB2448834A (en)	2008-10-29
UA86536C2 (ru)	2009-04-27
MY143239A (en)	2011-04-15
LT5550B (lt)	2009-03-25
CN101189220A (zh)	2008-05-28
FI20077133L (fi)	2007-12-20
JP2009179635A (ja)	2009-08-13
BG110024A (bg)	2008-05-30
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