DK189786A - 4-aminoalkylidensubstituerede 3-aryl-5(4h)-isoxazoloner, fremgangsmaader til fremstilling deraf, samt laegemidler indeholdende disse forbindelser og deres anvendelse - Google Patents

4-aminoalkylidensubstituerede 3-aryl-5(4h)-isoxazoloner, fremgangsmaader til fremstilling deraf, samt laegemidler indeholdende disse forbindelser og deres anvendelse Download PDF

Info

Publication number: DK189786A
Authority: DK; Denmark
Prior art keywords: compounds; substituted; aminoalkylidene; isoxazolones; aryl
Prior art date: 1985-04-26

Application number

DK189786A

Other languages

Danish (da)

English (en)

Other versions

DK189786D0 (da

Inventor

Alfred Kreutzberger

Karl Kolter

Peter Below

Franz Hock

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-26

Filing date

1986-04-24

Publication date

1986-10-27

1986-04-24 Application filed by Hoechst Ag filed Critical Hoechst Ag

1986-04-24 Publication of DK189786D0 publication Critical patent/DK189786D0/da

1986-10-27 Publication of DK189786A publication Critical patent/DK189786A/da

Links

150000001875 compounds Chemical class 0.000 title description 3
239000003814 drug Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 description 7
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 5
229910052736 halogen Inorganic materials 0.000 description 4
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 4
125000003545 alkoxy group Chemical group 0.000 description 3
229910052739 hydrogen Inorganic materials 0.000 description 3
239000001257 hydrogen Substances 0.000 description 3
125000004435 hydrogen atom Chemical group [H]* 0.000 description 3
125000004433 nitrogen atom Chemical group N* 0.000 description 3
125000004178 (C1-C4) alkyl group Chemical group 0.000 description 2
125000005843 halogen group Chemical group 0.000 description 2
150000002367 halogens Chemical class 0.000 description 2
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 2
229910052757 nitrogen Inorganic materials 0.000 description 2
229910052717 sulfur Inorganic materials 0.000 description 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 description 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 description 1
239000002253 acid Substances 0.000 description 1
125000004453 alkoxycarbonyl group Chemical group 0.000 description 1
125000002947 alkylene group Chemical group 0.000 description 1
125000002619 bicyclic group Chemical group 0.000 description 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
125000000490 cinnamyl group Chemical group C(C=CC1=CC=CC=C1)* 0.000 description 1
208000010877 cognitive disease Diseases 0.000 description 1
125000005842 heteroatom Chemical group 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 description 1
125000002950 monocyclic group Chemical group 0.000 description 1
229910052760 oxygen Inorganic materials 0.000 description 1
125000004430 oxygen atom Chemical group O* 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
125000004434 sulfur atom Chemical group 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK189786A 1985-04-26 1986-04-24 4-aminoalkylidensubstituerede 3-aryl-5(4h)-isoxazoloner, fremgangsmaader til fremstilling deraf, samt laegemidler indeholdende disse forbindelser og deres anvendelse DK189786A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19853515093 DE3515093A1 (de)	1985-04-26	1985-04-26	4-aminoalkylidensubstituierte 3-aryl-5(4h)-isoxazolone, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und ihre verwendung
DE3515093		1985-04-26

Publications (2)

Publication Number	Publication Date
DK189786D0 DK189786D0 (da)	1986-04-24
DK189786A true DK189786A (da)	1986-10-27

Family

ID=6269184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK189786A DK189786A (da)	1985-04-26	1986-04-24	4-aminoalkylidensubstituerede 3-aryl-5(4h)-isoxazoloner, fremgangsmaader til fremstilling deraf, samt laegemidler indeholdende disse forbindelser og deres anvendelse

Country Status (13)

Country	Link
EP (1)	EP0199323A3 (fr)
JP (1)	JPS61251674A (fr)
KR (1)	KR860008171A (fr)
AU (1)	AU5671486A (fr)
DE (1)	DE3515093A1 (fr)
DK (1)	DK189786A (fr)
ES (1)	ES8704484A1 (fr)
FI (1)	FI861729A7 (fr)
GR (1)	GR861100B (fr)
HU (1)	HU194193B (fr)
IL (1)	IL78616A0 (fr)
PT (1)	PT82454B (fr)
ZA (1)	ZA863112B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0367393A3 (fr) *	1988-10-31	1991-03-27	Takeda Chemical Industries, Ltd.	Composés hétérocycliques, préparation et utilisation de ces derniers
ES2097319T3 (es) *	1991-03-28	1997-04-01	Givaudan Roure Int	Derivados de isoxazol como agentes protectores de la luz.
GB2274282B (en) *	1993-01-19	1996-08-14	Erba Carlo Spa	Piperazine-and piperidine-isoxazole derivatives

1985
- 1985-04-26 DE DE19853515093 patent/DE3515093A1/de not_active Withdrawn
1986
- 1986-04-21 EP EP86105468A patent/EP0199323A3/fr not_active Withdrawn
- 1986-04-24 PT PT82454A patent/PT82454B/pt unknown
- 1986-04-24 HU HU861710A patent/HU194193B/hu unknown
- 1986-04-24 ES ES554312A patent/ES8704484A1/es not_active Expired
- 1986-04-24 FI FI861729A patent/FI861729A7/fi not_active Application Discontinuation
- 1986-04-24 AU AU56714/86A patent/AU5671486A/en not_active Abandoned
- 1986-04-24 DK DK189786A patent/DK189786A/da not_active Application Discontinuation
- 1986-04-25 GR GR861100A patent/GR861100B/el unknown
- 1986-04-25 IL IL78616A patent/IL78616A0/xx unknown
- 1986-04-25 KR KR1019860003198A patent/KR860008171A/ko not_active Withdrawn
- 1986-04-25 JP JP61094974A patent/JPS61251674A/ja active Pending
- 1986-04-25 ZA ZA863112A patent/ZA863112B/xx unknown

Also Published As

Publication number	Publication date
PT82454B (de)	1988-04-29
ZA863112B (en)	1987-06-24
IL78616A0 (en)	1986-08-31
DE3515093A1 (de)	1986-10-30
DK189786D0 (da)	1986-04-24
JPS61251674A (ja)	1986-11-08
EP0199323A3 (fr)	1987-10-28
ES8704484A1 (es)	1987-04-01
AU5671486A (en)	1986-10-30
HU194193B (en)	1988-01-28
ES554312A0 (es)	1987-04-01
HUT41749A (en)	1987-05-28
PT82454A (de)	1986-05-01
FI861729A0 (fi)	1986-04-24
GR861100B (en)	1986-08-19
KR860008171A (ko)	1986-11-12
FI861729A7 (fi)	1986-10-27
EP0199323A2 (fr)	1986-10-29

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Legal Events

Date	Code	Title	Description
1988-09-26	ATS	Application withdrawn