DK1899352T3 - 1-(2 ´,3 ´-dideoxxy-3 ´ C-(hydroxymethyl)-beta-D-erythro-pentofuranosyl)cytosinderivater som HIV-hæmmere - Google Patents
1-(2 ´,3 ´-dideoxxy-3 ´ C-(hydroxymethyl)-beta-D-erythro-pentofuranosyl)cytosinderivater som HIV-hæmmereInfo
- Publication number
- DK1899352T3 DK1899352T3 DK06777595.7T DK06777595T DK1899352T3 DK 1899352 T3 DK1899352 T3 DK 1899352T3 DK 06777595 T DK06777595 T DK 06777595T DK 1899352 T3 DK1899352 T3 DK 1899352T3
- Authority
- DK
- Denmark
- Prior art keywords
- pentofuranosyl
- erythro
- dideoxy
- hydroxymethyl
- beta
- Prior art date
Links
- WZGBNAXNHRMYLG-ZXFLCMHBSA-N 4-amino-1-[(2r,4r,5s)-4,5-bis(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one Chemical class O=C1N=C(N)C=CN1[C@@H]1O[C@H](CO)[C@@H](CO)C1 WZGBNAXNHRMYLG-ZXFLCMHBSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0513835.9A GB0513835D0 (en) | 2005-07-07 | 2005-07-07 | HIV inhibitors |
| PCT/EP2006/063919 WO2007006707A1 (en) | 2005-07-07 | 2006-07-05 | 1- [2' , 3' -dideoxy-3' c- (hydroxymethyl) - beta-d-erythro-pentofuranosyl] cytosine derivatives as hiv inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1899352T3 true DK1899352T3 (da) | 2012-01-30 |
Family
ID=34856749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06777595.7T DK1899352T3 (da) | 2005-07-07 | 2006-07-05 | 1-(2 ´,3 ´-dideoxxy-3 ´ C-(hydroxymethyl)-beta-D-erythro-pentofuranosyl)cytosinderivater som HIV-hæmmere |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US7888367B2 (da) |
| EP (2) | EP1899352B1 (da) |
| JP (1) | JP5174660B2 (da) |
| CN (1) | CN101213198B (da) |
| AT (1) | ATE527267T1 (da) |
| AU (1) | AU2006268743C1 (da) |
| BR (1) | BRPI0612678A2 (da) |
| CA (1) | CA2610210A1 (da) |
| CY (1) | CY1112164T1 (da) |
| DK (1) | DK1899352T3 (da) |
| ES (1) | ES2373743T3 (da) |
| GB (1) | GB0513835D0 (da) |
| HR (1) | HRP20110830T1 (da) |
| MX (1) | MX2008000221A (da) |
| PL (1) | PL1899352T3 (da) |
| PT (1) | PT1899352E (da) |
| WO (1) | WO2007006707A1 (da) |
| ZA (1) | ZA200710662B (da) |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8810907D0 (en) | 1988-05-09 | 1988-06-15 | British Telecomm | Fluoride glass optical coupler & method of manufacture |
| ZA902631B (en) * | 1989-04-06 | 1990-12-28 | Bristol Myers Squibb Co | 3'-substituted methyl nucleosides as antiviral agents |
| US5866775A (en) | 1990-09-28 | 1999-02-02 | Monsanto Company | Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases |
| US5627160A (en) * | 1993-05-25 | 1997-05-06 | Yale University | L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents |
| US5612319A (en) | 1994-05-31 | 1997-03-18 | Medivir Ab | Postexposure prevention of HIV infection or seroconversion |
| AU697612B2 (en) * | 1994-05-31 | 1998-10-15 | Medivir Ab | Post exposure prevention of HIV |
| PT988304E (pt) | 1997-08-15 | 2001-10-31 | Medivir Ab | Analogos de nucleosidos tais como os antivirais que contem inibidores de transcritase reversa retroviral e de adn-polimerase do virus da hepatite b (hbv) |
| EP1964569A3 (en) * | 2000-04-13 | 2009-07-22 | Pharmasset, Inc. | 3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of viral infections |
| US7109931B2 (en) | 2004-06-18 | 2006-09-19 | Centurion Wireless Technologies, Inc. | Method and apparatus to control an antenna efficiency test device |
| ES2325088T3 (es) * | 2004-12-30 | 2009-08-25 | Medivir Ab | Compuestos utiles en el tratamiento de hiv. |
-
2005
- 2005-07-07 GB GBGB0513835.9A patent/GB0513835D0/en not_active Ceased
-
2006
- 2006-07-05 JP JP2008519938A patent/JP5174660B2/ja not_active Expired - Fee Related
- 2006-07-05 PL PL06777595T patent/PL1899352T3/pl unknown
- 2006-07-05 DK DK06777595.7T patent/DK1899352T3/da active
- 2006-07-05 AU AU2006268743A patent/AU2006268743C1/en not_active Ceased
- 2006-07-05 CN CN2006800244086A patent/CN101213198B/zh not_active Expired - Fee Related
- 2006-07-05 HR HR20110830T patent/HRP20110830T1/hr unknown
- 2006-07-05 EP EP06777595A patent/EP1899352B1/en active Active
- 2006-07-05 AT AT06777595T patent/ATE527267T1/de not_active IP Right Cessation
- 2006-07-05 EP EP11161299A patent/EP2336135A3/en not_active Withdrawn
- 2006-07-05 ES ES06777595T patent/ES2373743T3/es active Active
- 2006-07-05 PT PT06777595T patent/PT1899352E/pt unknown
- 2006-07-05 MX MX2008000221A patent/MX2008000221A/es active IP Right Grant
- 2006-07-05 US US11/994,633 patent/US7888367B2/en not_active Expired - Fee Related
- 2006-07-05 WO PCT/EP2006/063919 patent/WO2007006707A1/en not_active Ceased
- 2006-07-05 BR BRPI0612678-2A patent/BRPI0612678A2/pt not_active IP Right Cessation
- 2006-07-05 CA CA002610210A patent/CA2610210A1/en not_active Abandoned
-
2007
- 2007-12-06 ZA ZA200710662A patent/ZA200710662B/xx unknown
-
2010
- 2010-12-30 US US12/982,667 patent/US8143396B2/en not_active Expired - Fee Related
-
2011
- 2011-12-22 CY CY20111101278T patent/CY1112164T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101213198A (zh) | 2008-07-02 |
| EP1899352B1 (en) | 2011-10-05 |
| EP1899352A1 (en) | 2008-03-19 |
| US8143396B2 (en) | 2012-03-27 |
| ATE527267T1 (de) | 2011-10-15 |
| HK1122798A1 (en) | 2009-05-29 |
| ZA200710662B (en) | 2008-11-26 |
| MX2008000221A (es) | 2008-03-18 |
| WO2007006707A1 (en) | 2007-01-18 |
| HRP20110830T1 (hr) | 2011-12-31 |
| AU2006268743C1 (en) | 2010-12-16 |
| BRPI0612678A2 (pt) | 2010-11-30 |
| CA2610210A1 (en) | 2007-01-18 |
| US20080221140A1 (en) | 2008-09-11 |
| PT1899352E (pt) | 2012-01-05 |
| JP2008545002A (ja) | 2008-12-11 |
| US20110112294A1 (en) | 2011-05-12 |
| JP5174660B2 (ja) | 2013-04-03 |
| GB0513835D0 (en) | 2005-08-10 |
| AU2006268743A1 (en) | 2007-01-18 |
| AU2006268743B2 (en) | 2010-07-29 |
| EP2336135A3 (en) | 2011-07-27 |
| CY1112164T1 (el) | 2015-12-09 |
| PL1899352T3 (pl) | 2012-03-30 |
| ES2373743T3 (es) | 2012-02-08 |
| CN101213198B (zh) | 2011-08-03 |
| US7888367B2 (en) | 2011-02-15 |
| EP2336135A2 (en) | 2011-06-22 |
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