ATE527267T1 - 1-ä2',3'-didesoxy-3'-c(hydroxymethyl)-b-d-eryth o-pentofuranosylü cytosinderivate als hiv- inhibitoren - Google Patents

1-ä2',3'-didesoxy-3'-c(hydroxymethyl)-b-d-eryth o-pentofuranosylü cytosinderivate als hiv- inhibitoren

Info

Publication number
ATE527267T1
ATE527267T1 AT06777595T AT06777595T ATE527267T1 AT E527267 T1 ATE527267 T1 AT E527267T1 AT 06777595 T AT06777595 T AT 06777595T AT 06777595 T AT06777595 T AT 06777595T AT E527267 T1 ATE527267 T1 AT E527267T1
Authority
AT
Austria
Prior art keywords
pentofuranosylü
didesoxy
eryth
hydroxymethyl
hiv inhibitors
Prior art date
Application number
AT06777595T
Other languages
English (en)
Inventor
Xiao-Xiong Zhou
Christer Sahlberg
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab filed Critical Medivir Ab
Application granted granted Critical
Publication of ATE527267T1 publication Critical patent/ATE527267T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06777595T 2005-07-07 2006-07-05 1-ä2',3'-didesoxy-3'-c(hydroxymethyl)-b-d-eryth o-pentofuranosylü cytosinderivate als hiv- inhibitoren ATE527267T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0513835.9A GB0513835D0 (en) 2005-07-07 2005-07-07 HIV inhibitors
PCT/EP2006/063919 WO2007006707A1 (en) 2005-07-07 2006-07-05 1- [2' , 3' -dideoxy-3' c- (hydroxymethyl) - beta-d-erythro-pentofuranosyl] cytosine derivatives as hiv inhibitors

Publications (1)

Publication Number Publication Date
ATE527267T1 true ATE527267T1 (de) 2011-10-15

Family

ID=34856749

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06777595T ATE527267T1 (de) 2005-07-07 2006-07-05 1-ä2',3'-didesoxy-3'-c(hydroxymethyl)-b-d-eryth o-pentofuranosylü cytosinderivate als hiv- inhibitoren

Country Status (18)

Country Link
US (2) US7888367B2 (de)
EP (2) EP1899352B1 (de)
JP (1) JP5174660B2 (de)
CN (1) CN101213198B (de)
AT (1) ATE527267T1 (de)
AU (1) AU2006268743C1 (de)
BR (1) BRPI0612678A2 (de)
CA (1) CA2610210A1 (de)
CY (1) CY1112164T1 (de)
DK (1) DK1899352T3 (de)
ES (1) ES2373743T3 (de)
GB (1) GB0513835D0 (de)
HR (1) HRP20110830T1 (de)
MX (1) MX2008000221A (de)
PL (1) PL1899352T3 (de)
PT (1) PT1899352E (de)
WO (1) WO2007006707A1 (de)
ZA (1) ZA200710662B (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810907D0 (en) 1988-05-09 1988-06-15 British Telecomm Fluoride glass optical coupler & method of manufacture
ZA902631B (en) * 1989-04-06 1990-12-28 Bristol Myers Squibb Co 3'-substituted methyl nucleosides as antiviral agents
US5866775A (en) 1990-09-28 1999-02-02 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases
US5627160A (en) * 1993-05-25 1997-05-06 Yale University L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
US5612319A (en) 1994-05-31 1997-03-18 Medivir Ab Postexposure prevention of HIV infection or seroconversion
AU697612B2 (en) * 1994-05-31 1998-10-15 Medivir Ab Post exposure prevention of HIV
PT988304E (pt) 1997-08-15 2001-10-31 Medivir Ab Analogos de nucleosidos tais como os antivirais que contem inibidores de transcritase reversa retroviral e de adn-polimerase do virus da hepatite b (hbv)
EP1964569A3 (de) * 2000-04-13 2009-07-22 Pharmasset, Inc. 3'- oder 2'-Hydroxymethyl-substituierte Nukleosidderivate zur Behandlung von Virusinfektionen
US7109931B2 (en) 2004-06-18 2006-09-19 Centurion Wireless Technologies, Inc. Method and apparatus to control an antenna efficiency test device
ES2325088T3 (es) * 2004-12-30 2009-08-25 Medivir Ab Compuestos utiles en el tratamiento de hiv.

Also Published As

Publication number Publication date
CN101213198A (zh) 2008-07-02
EP1899352B1 (de) 2011-10-05
EP1899352A1 (de) 2008-03-19
US8143396B2 (en) 2012-03-27
HK1122798A1 (en) 2009-05-29
ZA200710662B (en) 2008-11-26
MX2008000221A (es) 2008-03-18
WO2007006707A1 (en) 2007-01-18
DK1899352T3 (da) 2012-01-30
HRP20110830T1 (hr) 2011-12-31
AU2006268743C1 (en) 2010-12-16
BRPI0612678A2 (pt) 2010-11-30
CA2610210A1 (en) 2007-01-18
US20080221140A1 (en) 2008-09-11
PT1899352E (pt) 2012-01-05
JP2008545002A (ja) 2008-12-11
US20110112294A1 (en) 2011-05-12
JP5174660B2 (ja) 2013-04-03
GB0513835D0 (en) 2005-08-10
AU2006268743A1 (en) 2007-01-18
AU2006268743B2 (en) 2010-07-29
EP2336135A3 (de) 2011-07-27
CY1112164T1 (el) 2015-12-09
PL1899352T3 (pl) 2012-03-30
ES2373743T3 (es) 2012-02-08
CN101213198B (zh) 2011-08-03
US7888367B2 (en) 2011-02-15
EP2336135A2 (de) 2011-06-22

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