DK191688A - Terapeutiske nucleosider - Google Patents

Terapeutiske nucleosider

Info

Publication number
DK191688A
DK191688A DK191688A DK191688A DK191688A DK 191688 A DK191688 A DK 191688A DK 191688 A DK191688 A DK 191688A DK 191688 A DK191688 A DK 191688A DK 191688 A DK191688 A DK 191688A
Authority
DK
Denmark
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
Prior art date
Application number
DK191688A
Other languages
English (en)
Other versions
DK191688D0 (da
Inventor
George Walter Koszalka
Thomas Anthony Krenitsky
Janet Litster Rideout
Charlene Louise Burns
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878708512A external-priority patent/GB8708512D0/en
Priority claimed from GB878712691A external-priority patent/GB8712691D0/en
Priority claimed from GB878723013A external-priority patent/GB8723013D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK191688D0 publication Critical patent/DK191688D0/da
Publication of DK191688A publication Critical patent/DK191688A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK191688A 1987-04-09 1988-04-08 Terapeutiske nucleosider DK191688A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878708512A GB8708512D0 (en) 1987-04-09 1987-04-09 Therapeutic nucleosides
GB878712691A GB8712691D0 (en) 1987-05-29 1987-05-29 Therapeutic nucleosides
GB878723013A GB8723013D0 (en) 1987-09-30 1987-09-30 Therapeutic nucleosides

Publications (2)

Publication Number Publication Date
DK191688D0 DK191688D0 (da) 1988-04-08
DK191688A true DK191688A (da) 1988-10-10

Family

ID=27263377

Family Applications (1)

Application Number Title Priority Date Filing Date
DK191688A DK191688A (da) 1987-04-09 1988-04-08 Terapeutiske nucleosider

Country Status (20)

Country Link
US (1) US5068320A (da)
EP (1) EP0286425B1 (da)
JP (1) JP2763888B2 (da)
KR (1) KR880012630A (da)
AP (1) AP78A (da)
AT (1) ATE116984T1 (da)
AU (1) AU608590B2 (da)
CA (1) CA1326237C (da)
CS (1) CS274461B2 (da)
DE (1) DE3852710T2 (da)
DK (1) DK191688A (da)
FI (1) FI87214C (da)
HU (1) HU201954B (da)
IL (1) IL86007A0 (da)
MC (1) MC1915A1 (da)
NO (1) NO171641C (da)
NZ (1) NZ224189A (da)
PL (1) PL154956B1 (da)
PT (1) PT87191B (da)
RU (1) RU1779256C (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185437A (en) * 1987-04-09 1993-02-09 Burroughs Wellcome Co. Therapeutic nucleosides
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
US5077280A (en) * 1988-04-12 1991-12-31 Brown University Research Foundation Treatment of viral infections
IE882585L (en) * 1988-08-25 1990-02-25 Prendergast Patrick T Viral treatment system
EP0366385B1 (en) * 1988-10-24 1993-06-09 The Wellcome Foundation Limited Guanine derivatives having antiviral activity and their pharmaceutically acceptable salts
WO1990006312A1 (de) * 1988-11-29 1990-06-14 Institut Für Molekularbiologie Und Analytik (Ima) Gmbh 2', 3'-didesoxyribofuranoside und ein verfahren zu ihrer herstellung
JP2619710B2 (ja) * 1989-02-27 1997-06-11 日本製紙 株式会社 ２′，３′−ジデオキシプリンヌクレオシド類の製造方法
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
US5013829A (en) * 1989-04-26 1991-05-07 University Of Iowa Research Foundation Stable congener of 2',3'-dideoxyadenosine
DE4020529A1 (de) * 1989-09-12 1991-03-21 Roxana Vasiloiu Multifunktionelle(s) enzym(e) mit nucleosid-didesoxyribosyltransferase(n) und/oder nucleoside-desoxyribosyltransferasen(n) und/oder kinease- und/oder reduktase- und/oder desaminase- und/oder polymerase-aktivitaet
JPH0637391B2 (ja) * 1989-09-29 1994-05-18 日本製紙株式会社 抗エイズウイルス剤
PT95516A (pt) * 1989-10-06 1991-08-14 Wellcome Found Processo para a preparacao de derivados de 2',3'-didesoxi nucleosidos 6-substituidos
CA2075490A1 (en) * 1990-02-09 1991-08-10 Hiroaki Mitsuya 6-halo-and 2-amino-6-halo-purine 2',3'-dideoxy nucleosides and their use as antiviral agents
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
IL143867A0 (en) * 1998-12-23 2002-04-21 Shire Biochem Inc Antiviral nucleoside analogues
CN101220071B (zh) * 2008-01-17 2011-04-06 南京长澳医药科技有限公司 稳定的6-甲氧基-2’,3’-双脱氧鸟嘌呤核苷及其制备方法和包含它的药物组合物
CN102234280B (zh) * 2010-04-26 2014-01-08 北京大学 D,l-鸟嘌呤核苷类似物及其制备方法和应用
WO2012040127A1 (en) 2010-09-22 2012-03-29 Alios Biopharma, Inc. Substituted nucleotide analogs
AU2012262021B2 (en) * 2011-06-01 2016-07-28 Janus Biotherapeutics, Inc. Novel immune system modulators
EP2794630A4 (en) 2011-12-22 2015-04-01 Alios Biopharma Inc SUBSTITUTED PHOSPHORTHIOAT NUCLEOTIDE ANALOGUE
NZ631601A (en) 2012-03-21 2016-06-24 Alios Biopharma Inc Solid forms of a thiophosphoramidate nucleotide prodrug
NZ630805A (en) 2012-03-22 2016-01-29 Alios Biopharma Inc Pharmaceutical combinations comprising a thionucleotide analog
JP2016513621A (ja) * 2013-03-05 2016-05-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ブルトンチロシンキナーゼの阻害剤

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1573777A (en) * 1977-11-03 1980-08-28 Wellcome Found 9-d-arabinonucleosides and an enzymatic process for their preparation
NZ215486A (en) * 1985-03-16 1988-09-29 Wellcome Found 3'-azido-3'-deoxythymidine antiretroviral compositions (zidovudine, azt)
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
PT82580B (pt) * 1985-05-15 1989-01-17 Wellcome Found Processo para a preparacao de 2',3'- didesoxinucleosidos e de composicoes farmaceuticas que os contem
AU570855B2 (en) * 1985-08-26 1988-03-24 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Inhibition of in vitro infectivity and cytopathic effect of htlv-111/lav by 2' 3' -dideoxycytidine
DK167377B1 (da) * 1985-09-17 1993-10-25 Wellcome Found 3'-azidopyrimidinnucleosider eller farmaceutisk acceptable salte eller estere deraf til anvendelse ved behandling af eller profylakse for en human retrovirusinfektion
IT1203558B (it) * 1986-05-20 1989-02-15 Firestone Int Dev Spa Metodo per la realizzazione di un pneumatico radiale di prima fase per veicoli
ATE108183T1 (de) * 1987-03-24 1994-07-15 Nycomed Imaging As 2',3'-dideoxyribofuranoxid-derivate.
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
NZ225447A (en) * 1987-07-20 1991-12-23 Merck & Co Inc Piperazinyl derivatives of purine and purine isosteres and pharmaceutical compositions

Also Published As

Publication number Publication date
DE3852710D1 (de) 1995-02-23
MC1915A1 (fr) 1989-04-06
NO171641B (no) 1993-01-04
NO881537L (no) 1988-10-10
KR880012630A (ko) 1988-11-28
EP0286425B1 (en) 1995-01-11
PL154956B1 (en) 1991-10-31
RU1779256C (ru) 1992-11-30
CS274461B2 (en) 1991-04-11
FI881651A0 (fi) 1988-04-08
FI87214C (fi) 1992-12-10
CA1326237C (en) 1994-01-18
IL86007A0 (en) 1988-09-30
PT87191B (pt) 1993-02-26
AU1444488A (en) 1988-10-13
US5068320A (en) 1991-11-26
NZ224189A (en) 1991-09-25
JP2763888B2 (ja) 1998-06-11
AU608590B2 (en) 1991-04-11
AP78A (en) 1990-03-12
JPS63267796A (ja) 1988-11-04
NO881537D0 (no) 1988-04-08
PT87191A (pt) 1988-05-01
HUT48269A (en) 1989-05-29
FI87214B (fi) 1992-08-31
EP0286425A3 (en) 1990-12-05
AP8800086A0 (en) 1988-02-01
PL271722A1 (en) 1989-01-23
DE3852710T2 (de) 1995-05-24
NO171641C (no) 1993-04-14
CS242188A2 (en) 1990-09-12
DK191688D0 (da) 1988-04-08
FI881651L (fi) 1988-10-10
HU201954B (en) 1991-01-28
EP0286425A2 (en) 1988-10-12
ATE116984T1 (de) 1995-01-15

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment