DK192388A - Rhodomyciner, deres fremstilling og anvendelse. - Google Patents
Rhodomyciner, deres fremstilling og anvendelse.Info
- Publication number
- DK192388A DK192388A DK192388A DK192388A DK192388A DK 192388 A DK192388 A DK 192388A DK 192388 A DK192388 A DK 192388A DK 192388 A DK192388 A DK 192388A DK 192388 A DK192388 A DK 192388A
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- hydrogen
- alpha
- rhodosaminyl
- acyl derivatives
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 150000002431 hydrogen Chemical class 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005336 allyloxy group Chemical group 0.000 abstract 1
- 229940045799 anthracyclines and related substance Drugs 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- -1 hydroxymethylene Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873712350 DE3712350A1 (de) | 1987-04-11 | 1987-04-11 | Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK192388D0 DK192388D0 (da) | 1988-04-08 |
| DK192388A true DK192388A (da) | 1988-10-12 |
Family
ID=6325447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK192388A DK192388A (da) | 1987-04-11 | 1988-04-08 | Rhodomyciner, deres fremstilling og anvendelse. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0286926B1 (da) |
| JP (1) | JP2672965B2 (da) |
| KR (1) | KR880012624A (da) |
| AT (1) | ATE116991T1 (da) |
| AU (1) | AU614954B2 (da) |
| CA (1) | CA1340690C (da) |
| DE (2) | DE3712350A1 (da) |
| DK (1) | DK192388A (da) |
| ES (1) | ES2067452T3 (da) |
| FI (1) | FI90777C (da) |
| GR (1) | GR3015231T3 (da) |
| PT (1) | PT87193B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3722698A1 (de) * | 1987-07-09 | 1989-01-19 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| FR2630914A1 (fr) * | 1988-05-04 | 1989-11-10 | Hoechst Sa Laboratoires | Nouveaux analogues du l-fucose, leur procede de preparation, application de ces analogues a la preparation de nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments |
| FR2630915A1 (fr) * | 1988-05-04 | 1989-11-10 | Hoechst Lab | Nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments |
| DE3836122A1 (de) * | 1988-10-22 | 1990-05-31 | Behringwerke Ag | Verfahren zur herstellung von 4-0-alkyl-rhodomycinen |
| DE3842836A1 (de) * | 1988-12-20 | 1990-06-21 | Behringwerke Ag | Rhodomycine mit einer modifizierten kohlenhydrat-einheit |
| WO1990007519A1 (en) * | 1988-12-28 | 1990-07-12 | Board Of Regents, The University Of Texas System | 3'-deamino analogs of esorubicin and methods for their use |
| DE3920062A1 (de) * | 1989-06-20 | 1991-01-10 | Hoechst Ag | Neue anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| BR112021003156A2 (pt) | 2018-08-23 | 2021-05-11 | Seagen, Inc. | composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2056443B (en) * | 1979-08-20 | 1984-01-18 | Hoffmann La Roche | Cyclic compounds |
| US4302449A (en) * | 1980-09-02 | 1981-11-24 | Board Of Control Of Michigan Technological University | Carminomycin analogue |
| GB2120667B (en) * | 1982-05-24 | 1985-06-05 | Erba Farmitalia | Anthracycline glycosides |
| DE3323025A1 (de) * | 1983-06-25 | 1985-01-10 | Hoechst Ag, 6230 Frankfurt | Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
| DE3425357A1 (de) * | 1984-07-10 | 1986-01-23 | Hoechst Ag, 6230 Frankfurt | 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika |
| JPS6133194A (ja) * | 1984-07-25 | 1986-02-17 | Sanraku Inc | 新規アントラサイクリン抗生物質 |
| JPS61236792A (ja) * | 1985-04-12 | 1986-10-22 | Sanraku Inc | 新規アントラサイクリン抗生物質 |
| JPS62238298A (ja) * | 1986-04-08 | 1987-10-19 | Sanraku Inc | 新規アントラサイクリン抗生物質dcp−1及び2 |
| JPS6391395A (ja) * | 1986-10-03 | 1988-04-22 | Kirin Brewery Co Ltd | アンスラサイクリン化合物、その製造法およびその用途 |
| DE3641835A1 (de) * | 1986-12-08 | 1988-06-16 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| DE3641833A1 (de) | 1986-12-08 | 1988-06-09 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| JPS63227599A (ja) * | 1987-03-14 | 1988-09-21 | Kirin Brewery Co Ltd | アンスラサイクリン化合物およびその用途 |
| DE3722698A1 (de) * | 1987-07-09 | 1989-01-19 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
-
1987
- 1987-04-11 DE DE19873712350 patent/DE3712350A1/de not_active Ceased
-
1988
- 1988-04-01 ES ES88105330T patent/ES2067452T3/es not_active Expired - Lifetime
- 1988-04-01 EP EP88105330A patent/EP0286926B1/de not_active Expired - Lifetime
- 1988-04-01 DE DE3852711T patent/DE3852711D1/de not_active Expired - Fee Related
- 1988-04-01 AT AT88105330T patent/ATE116991T1/de not_active IP Right Cessation
- 1988-04-07 FI FI881610A patent/FI90777C/fi not_active IP Right Cessation
- 1988-04-08 JP JP63085542A patent/JP2672965B2/ja not_active Expired - Fee Related
- 1988-04-08 DK DK192388A patent/DK192388A/da not_active Application Discontinuation
- 1988-04-08 CA CA000563694A patent/CA1340690C/en not_active Expired - Fee Related
- 1988-04-08 PT PT87193A patent/PT87193B/pt not_active IP Right Cessation
- 1988-04-09 KR KR1019880004037A patent/KR880012624A/ko not_active Ceased
- 1988-04-11 AU AU14468/88A patent/AU614954B2/en not_active Ceased
-
1995
- 1995-02-28 GR GR950400437T patent/GR3015231T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1446888A (en) | 1988-10-13 |
| AU614954B2 (en) | 1991-09-19 |
| EP0286926A2 (de) | 1988-10-19 |
| EP0286926B1 (de) | 1995-01-11 |
| KR880012624A (ko) | 1988-11-28 |
| PT87193A (pt) | 1988-05-01 |
| EP0286926A3 (en) | 1990-09-19 |
| ATE116991T1 (de) | 1995-01-15 |
| DE3712350A1 (de) | 1988-10-20 |
| FI90777B (fi) | 1993-12-15 |
| JP2672965B2 (ja) | 1997-11-05 |
| FI881610A7 (fi) | 1988-10-12 |
| FI881610A0 (fi) | 1988-04-07 |
| GR3015231T3 (en) | 1995-05-31 |
| FI90777C (fi) | 1994-03-25 |
| JPS63267775A (ja) | 1988-11-04 |
| CA1340690C (en) | 1999-08-03 |
| DE3852711D1 (de) | 1995-02-23 |
| DK192388D0 (da) | 1988-04-08 |
| PT87193B (pt) | 1992-07-31 |
| ES2067452T3 (es) | 1995-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |