GR3015231T3 - Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics. - Google Patents

Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics.

Info

Publication number
GR3015231T3
GR3015231T3 GR950400437T GR950400437T GR3015231T3 GR 3015231 T3 GR3015231 T3 GR 3015231T3 GR 950400437 T GR950400437 T GR 950400437T GR 950400437 T GR950400437 T GR 950400437T GR 3015231 T3 GR3015231 T3 GR 3015231T3
Authority
GR
Greece
Prior art keywords
formula
hydrogen
alpha
rhodosaminyl
acyl derivatives
Prior art date
Application number
GR950400437T
Other languages
English (en)
Inventor
Manfred Dr Gerken
Cenek Dr Kolar
Hans Peter Dr Kraemer
Dieter Dr Hoffmann
Peter Dr Hermentin
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of GR3015231T3 publication Critical patent/GR3015231T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
GR950400437T 1987-04-11 1995-02-28 Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics. GR3015231T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873712350 DE3712350A1 (de) 1987-04-11 1987-04-11 Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika

Publications (1)

Publication Number Publication Date
GR3015231T3 true GR3015231T3 (en) 1995-05-31

Family

ID=6325447

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950400437T GR3015231T3 (en) 1987-04-11 1995-02-28 Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics.

Country Status (12)

Country Link
EP (1) EP0286926B1 (el)
JP (1) JP2672965B2 (el)
KR (1) KR880012624A (el)
AT (1) ATE116991T1 (el)
AU (1) AU614954B2 (el)
CA (1) CA1340690C (el)
DE (2) DE3712350A1 (el)
DK (1) DK192388A (el)
ES (1) ES2067452T3 (el)
FI (1) FI90777C (el)
GR (1) GR3015231T3 (el)
PT (1) PT87193B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3722698A1 (de) * 1987-07-09 1989-01-19 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
FR2630914A1 (fr) * 1988-05-04 1989-11-10 Hoechst Sa Laboratoires Nouveaux analogues du l-fucose, leur procede de preparation, application de ces analogues a la preparation de nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments
FR2630915A1 (fr) * 1988-05-04 1989-11-10 Hoechst Lab Nouveaux glycals, anthracyclines obtenues a l'aide de ces glycals et utilisation desdites anthracyclines en tant que medicaments
DE3836122A1 (de) * 1988-10-22 1990-05-31 Behringwerke Ag Verfahren zur herstellung von 4-0-alkyl-rhodomycinen
DE3842836A1 (de) * 1988-12-20 1990-06-21 Behringwerke Ag Rhodomycine mit einer modifizierten kohlenhydrat-einheit
WO1990007519A1 (en) * 1988-12-28 1990-07-12 Board Of Regents, The University Of Texas System 3'-deamino analogs of esorubicin and methods for their use
DE3920062A1 (de) * 1989-06-20 1991-01-10 Hoechst Ag Neue anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
BR112021003156A2 (pt) 2018-08-23 2021-05-11 Seagen, Inc. composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2056443B (en) * 1979-08-20 1984-01-18 Hoffmann La Roche Cyclic compounds
US4302449A (en) * 1980-09-02 1981-11-24 Board Of Control Of Michigan Technological University Carminomycin analogue
GB2120667B (en) * 1982-05-24 1985-06-05 Erba Farmitalia Anthracycline glycosides
DE3323025A1 (de) * 1983-06-25 1985-01-10 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3425357A1 (de) * 1984-07-10 1986-01-23 Hoechst Ag, 6230 Frankfurt 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
JPS6133194A (ja) * 1984-07-25 1986-02-17 Sanraku Inc 新規アントラサイクリン抗生物質
JPS61236792A (ja) * 1985-04-12 1986-10-22 Sanraku Inc 新規アントラサイクリン抗生物質
JPS62238298A (ja) * 1986-04-08 1987-10-19 Sanraku Inc 新規アントラサイクリン抗生物質ｄｃｐ−１及び２
JPS6391395A (ja) * 1986-10-03 1988-04-22 Kirin Brewery Co Ltd アンスラサイクリン化合物、その製造法およびその用途
DE3641835A1 (de) * 1986-12-08 1988-06-16 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
DE3641833A1 (de) 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
JPS63227599A (ja) * 1987-03-14 1988-09-21 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
DE3722698A1 (de) * 1987-07-09 1989-01-19 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate

Also Published As

Publication number Publication date
AU1446888A (en) 1988-10-13
AU614954B2 (en) 1991-09-19
EP0286926A2 (de) 1988-10-19
EP0286926B1 (de) 1995-01-11
KR880012624A (ko) 1988-11-28
PT87193A (pt) 1988-05-01
EP0286926A3 (en) 1990-09-19
ATE116991T1 (de) 1995-01-15
DE3712350A1 (de) 1988-10-20
FI90777B (fi) 1993-12-15
JP2672965B2 (ja) 1997-11-05
FI881610A7 (fi) 1988-10-12
DK192388A (da) 1988-10-12
FI881610A0 (fi) 1988-04-07
FI90777C (fi) 1994-03-25
JPS63267775A (ja) 1988-11-04
CA1340690C (en) 1999-08-03
DE3852711D1 (de) 1995-02-23
DK192388D0 (da) 1988-04-08
PT87193B (pt) 1992-07-31
ES2067452T3 (es) 1995-04-01

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