DK194490D0 - 5-ht-selektive midler - Google Patents

5-ht-selektive midler

Info

Publication number
DK194490D0
DK194490D0 DK194490A DK194490A DK194490D0 DK 194490 D0 DK194490 D0 DK 194490D0 DK 194490 A DK194490 A DK 194490A DK 194490 A DK194490 A DK 194490A DK 194490 D0 DK194490 D0 DK 194490D0
Authority
DK
Denmark
Prior art keywords
alkoxy
selective agents
hexahydro
selective
agents
Prior art date
Application number
DK194490A
Other languages
English (en)
Other versions
DK194490A (da
DK171061B1 (da
Inventor
John F Debernardis
Michael D Meyer
Kevin B Sippy
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of DK194490D0 publication Critical patent/DK194490D0/da
Publication of DK194490A publication Critical patent/DK194490A/da
Application granted granted Critical
Publication of DK171061B1 publication Critical patent/DK171061B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Indole Compounds (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Pyridine Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Networks Using Active Elements (AREA)
  • Amplifiers (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Read Only Memory (AREA)
  • Manipulation Of Pulses (AREA)
  • Logic Circuits (AREA)
DK194490A 1988-12-15 1990-08-15 Hexahydro-1H-indeno(2,1-c)pyridinforbindelser, farmaceutiske midler indeholdende disse samt anvendelsen heraf til fremstilling af lægemidler til behandling af hypertension, ængstelse eller depression DK171061B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28513488A 1988-12-15 1988-12-15
US28513488 1988-12-15
PCT/US1989/005512 WO1990006927A1 (en) 1988-12-15 1989-12-07 5-ht selective agents
US8905512 1989-12-07

Publications (3)

Publication Number Publication Date
DK194490D0 true DK194490D0 (da) 1990-08-15
DK194490A DK194490A (da) 1990-10-12
DK171061B1 DK171061B1 (da) 1996-05-13

Family

ID=23092880

Family Applications (2)

Application Number Title Priority Date Filing Date
DK194490A DK171061B1 (da) 1988-12-15 1990-08-15 Hexahydro-1H-indeno(2,1-c)pyridinforbindelser, farmaceutiske midler indeholdende disse samt anvendelsen heraf til fremstilling af lægemidler til behandling af hypertension, ængstelse eller depression
DK024595A DK24595A (da) 1988-12-15 1995-03-10 8-alkoxy-1,2,3,3a,8,8a-hexahydro-indeno[1,2-a]-pyrrol- og 9-alkoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindolforbindelser, farmaceutiske midler indeholdende disse samt anvendelsen heraf til fremstilling af lægemidler til behandling af hypertension

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK024595A DK24595A (da) 1988-12-15 1995-03-10 8-alkoxy-1,2,3,3a,8,8a-hexahydro-indeno[1,2-a]-pyrrol- og 9-alkoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e]isoindolforbindelser, farmaceutiske midler indeholdende disse samt anvendelsen heraf til fremstilling af lægemidler til behandling af hypertension

Country Status (10)

Country Link
EP (1) EP0422134B1 (da)
JP (1) JPH03502701A (da)
KR (1) KR910700251A (da)
AT (1) ATE139230T1 (da)
AU (1) AU626621B2 (da)
CA (1) CA2005441A1 (da)
DE (1) DE68926673T2 (da)
DK (2) DK171061B1 (da)
ES (1) ES2090119T3 (da)
WO (1) WO1990006927A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9014061D0 (en) * 1990-06-25 1990-08-15 Merck Sharp & Dohme Therapeutic agents
JPH07500333A (ja) * 1991-10-24 1995-01-12 ジ・アップジョン・カンパニー ベンゾ−イソキノリン誘導体
EP0539209A1 (en) * 1991-10-24 1993-04-28 The Upjohn Company Benzo-isoquinoline derivatives and analogs and their use in therapeutics
US5512566A (en) * 1993-10-25 1996-04-30 Ortho Pharmaceutical Corporation Tricyclic compounds having affinity for the 5-HT1A receptor
KR950014099A (ko) * 1993-11-10 1995-06-15 장기하 N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법
FR2722194B1 (fr) * 1994-07-06 1996-08-23 Adir Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
ATE374192T1 (de) 2000-11-29 2007-10-15 Lilly Co Eli 1-(2-m-methansulfonamidophenylethyl)-4-(m- trifluoromethylphenyl)piperazine und ihre akzeptablen pharmazeutischen salze und solvate und ihre verwendung zur behandlung von inkontinenz
EP1841738A4 (en) 2004-07-29 2010-06-02 Athersys Inc TRICYCLIC INDENOPYRROLE DERIVATIVES AS MODULATORS OF SEROTONIN RECEPTORS
TW200924752A (en) * 2007-09-17 2009-06-16 Organon Nv Tricyclic heterocyclic derivatives
TW201041851A (en) 2009-03-10 2010-12-01 Organon Nv Tricyclic heterocyclic derivatives
US8546377B2 (en) 2009-04-23 2013-10-01 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
US8518933B2 (en) 2009-04-23 2013-08-27 Abbvie Inc. Modulators of 5-HT receptors and methods of use thereof
SG176100A1 (en) 2009-05-22 2011-12-29 Abbott Lab Modulators of 5-ht receptors and methods of use thereof
KR101770979B1 (ko) 2010-05-21 2017-08-24 애브비 인코포레이티드 5­ｈｔ 수용체의 조절제 및 이의 사용방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792374A (fr) * 1971-12-08 1973-06-06 Allen & Hanburys Ltd Nouveaux derives d'isoindoline
US4341786A (en) * 1981-03-02 1982-07-27 Smithkline Corporation Pharmaceutical compositions and method of producing central alpha1 agonist activity utilizing octahydrobenzo[f]quinoline compounds
US4438346A (en) * 1981-10-15 1984-03-20 Advanced Micro Devices, Inc. Regulated substrate bias generator for random access memory
AU560459B2 (en) * 1982-06-01 1987-04-09 Abbott Laboratories Tetrahydro-benzo(e) isoindolines
US4618683A (en) * 1982-06-01 1986-10-21 Abbott Laboratories Tetrahydro-6,7-dimethoxy-1H-benz[e]isoinodolines useful in the treatment of hypertension and as sedatives
SE8302361D0 (sv) * 1983-04-27 1983-04-27 Astra Laekemedel Ab New tricyclic amines
DE3401931C2 (de) * 1984-01-20 1986-06-12 Continental Gummi-Werke Ag, 3000 Hannover Biegsamer Schlauch
DE3576334D1 (de) * 1984-07-25 1990-04-12 Abbott Lab 1,2,3,3a,8,8a-hexahydro-indeno-(1,2-c)pyrrde.
DE3522959A1 (de) * 1985-06-27 1987-01-08 Merck Patent Gmbh Indolderivate
US4842852A (en) * 1988-03-10 1989-06-27 National Starch And Chemical Corporation Hydrocarbon tolerant hair fixing compositions

Also Published As

Publication number Publication date
KR910700251A (ko) 1991-03-14
DK194490A (da) 1990-10-12
JPH03502701A (ja) 1991-06-20
ES2090119T3 (es) 1996-10-16
EP0422134A4 (en) 1992-05-06
DE68926673D1 (de) 1996-07-18
DK171061B1 (da) 1996-05-13
CA2005441A1 (en) 1990-06-15
ATE139230T1 (de) 1996-06-15
AU4746090A (en) 1990-07-10
EP0422134A1 (en) 1991-04-17
AU626621B2 (en) 1992-08-06
DE68926673T2 (de) 1997-01-16
EP0422134B1 (en) 1996-06-12
WO1990006927A1 (en) 1990-06-28
DK24595A (da) 1995-03-10

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed