DK1994939T3 - Farmaceutisk sammensætning indeholdende GHRP-6 til forebyggelse og eliminering af fibrose og øvrige patologiske deponeringer i væv - Google Patents

Farmaceutisk sammensætning indeholdende GHRP-6 til forebyggelse og eliminering af fibrose og øvrige patologiske deponeringer i væv

Info

Publication number: DK1994939T3
Authority: DK; Denmark
Prior art keywords: fibrosis; elimination; tissues; prevention; pharmaceutical composition
Prior art date: 2006-02-28

Application number

DK07711099.7T

Other languages

English (en)

Inventor

Mola Ernesto Lopez

Sosa Manuel Selman-Housein

Del Barco Herrera Diana Garcia

Nieto Gerardo Enrique Guillen

Acosta Jorge Berlanga

Vera Danay Cibrian

Alba Jose Suarez

Castillo Mariela Vazquez

Original Assignee

Ct Ingenieria Genetica Biotech

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-28

Filing date

2007-02-23

Publication date

2012-09-10

2007-02-23 Application filed by Ct Ingenieria Genetica Biotech filed Critical Ct Ingenieria Genetica Biotech

2012-09-10 Application granted granted Critical

2012-09-10 Publication of DK1994939T3 publication Critical patent/DK1994939T3/da

Links

WZHKXNSOCOQYQX-FUAFALNISA-N (2s)-6-amino-2-[[(2r)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CN=CN1 WZHKXNSOCOQYQX-FUAFALNISA-N 0.000 title 1
206010016654 Fibrosis Diseases 0.000 title 1
230000008030 elimination Effects 0.000 title 1
238000003379 elimination reaction Methods 0.000 title 1
230000004761 fibrosis Effects 0.000 title 1
108010015153 growth hormone releasing hexapeptide Proteins 0.000 title 1
230000001575 pathological effect Effects 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
230000002265 prevention Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Zoology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

DK07711099.7T 2006-02-28 2007-02-23 Farmaceutisk sammensætning indeholdende GHRP-6 til forebyggelse og eliminering af fibrose og øvrige patologiske deponeringer i væv DK1994939T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CU20060048A CU23592A1 (es)	2006-02-28	2006-02-28	Método para prevenir y eliminar las fibrosis y otras formas de depósito patológico en los tejidos aplicando el péptido secretagogo ghrp-6
PCT/CU2007/000005 WO2007098715A1 (es)	2006-02-28	2007-02-23	Composición farmacéutica conteniendo ghrp-6 capaz de prevenir y eliminar las fibrosis y otras formas de depósito patológico en los tejidos

Publications (1)

Publication Number	Publication Date
DK1994939T3 true DK1994939T3 (da)	2012-09-10

Family

ID=37964643

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07711099.7T DK1994939T3 (da)	2006-02-28	2007-02-23	Farmaceutisk sammensætning indeholdende GHRP-6 til forebyggelse og eliminering af fibrose og øvrige patologiske deponeringer i væv

Country Status (16)

Country	Link
US (2)	US20090221512A1 (da)
EP (2)	EP2368563A1 (da)
JP (1)	JP5426175B2 (da)
KR (1)	KR101462077B1 (da)
CN (1)	CN101426517B (da)
AR (1)	AR059644A1 (da)
AU (1)	AU2007219568B2 (da)
BR (1)	BRPI0708349B8 (da)
CA (1)	CA2644431C (da)
CU (1)	CU23592A1 (da)
DK (1)	DK1994939T3 (da)
ES (1)	ES2388879T3 (da)
MX (1)	MX2008011140A (da)
RU (1)	RU2465913C2 (da)
WO (1)	WO2007098715A1 (da)
ZA (1)	ZA200807600B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8592377B2 (en)	2007-03-28	2013-11-26	President And Fellows Of Harvard College	Stitched polypeptides
ES2711526T3 (es)	2010-08-13	2019-05-06	Aileron Therapeutics Inc	Macrociclos peptidomiméticos
TW201806968A (zh)	2011-10-18	2018-03-01	艾利倫治療公司	擬肽巨環化合物
EP2819688A4 (en)	2012-02-15	2015-10-28	Aileron Therapeutics Inc	TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
BR112014020103A2 (pt)	2012-02-15	2018-10-09	Aileron Therapeutics, Inc.	macrociclos peptidomiméticos
KR101667383B1 (ko) *	2012-03-28	2016-10-18	주식회사 인코스팜	비오틴이 결합된 ｈｅｘａｐｅｐｔｉｄｅ-２ 유도체 및 이의 용도
WO2014071241A1 (en)	2012-11-01	2014-05-08	Aileron Therapeutics, Inc.	Disubstituted amino acids and methods of preparation and use thereof
KR102051433B1 (ko) *	2013-08-27	2020-01-08	(주)네오팜	근육 분화 촉진 및 근육 강화용 조성물 및 외용제
US9119832B2 (en) *	2014-02-05	2015-09-01	The Regents Of The University Of California	Methods of treating mild brain injury
EP3197478A4 (en)	2014-09-24	2018-05-30	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
WO2016154058A1 (en)	2015-03-20	2016-09-29	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
FR3034662B1 (fr) *	2015-04-10	2020-08-28	Isp Investments Inc	Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane
CN106730414B (zh) *	2015-12-30	2017-10-10	南京中硼联康医疗科技有限公司	用于消除β淀粉样蛋白的中子捕获治疗系统
KR102394643B1 (ko) *	2016-10-18	2022-05-09	(주)아모레퍼시픽	후발효차 유래의 신규한 캄페롤계 화합물을 포함하는 인지기능 개선용 조성물
CN109908331A (zh) *	2019-04-30	2019-06-21	青岛大学附属医院	海沙瑞林在制备保护肾脏缺血再灌注损伤药物/药物组合物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4411890A (en) *	1981-04-14	1983-10-25	Beckman Instruments, Inc.	Synthetic peptides having pituitary growth hormone releasing activity
TW432073B (en) *	1995-12-28	2001-05-01	Pfizer	Pyrazolopyridine compounds
CA2395996A1 (en) *	1999-12-28	2001-07-05	Kaken Pharmaceutical Co., Ltd.	Neuroprotective drug
CU23157A1 (es) *	2001-01-03	2006-07-18	Ct Ingenieria Genetica Biotech	COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
WO2003047624A1 (fr) *	2001-12-07	2003-06-12	Kaken Pharmaceutical Co., Ltd.	Inhibiteur de migration cellulaire
TWI331922B (en) *	2002-08-09	2010-10-21	Ipsen Pharma Sas	Growth hormone releasing peptides
JP4467518B2 (ja) *	2003-04-30	2010-05-26	賢治寒川	肝障害予防治療剤
JP2005239712A (ja) *	2004-01-30	2005-09-08	Kaken Pharmaceut Co Ltd	神経突起伸展剤
US20090149512A1 (en) *	2004-05-14	2009-06-11	Novo Nordisk A/S	Use of Ghrelin Antagonists to the Treatment of Certain CNS Diseases

2006
- 2006-02-28 CU CU20060048A patent/CU23592A1/es unknown
2007
- 2007-02-23 EP EP11170318A patent/EP2368563A1/en not_active Withdrawn
- 2007-02-23 US US12/281,018 patent/US20090221512A1/en not_active Abandoned
- 2007-02-23 CA CA2644431A patent/CA2644431C/en active Active
- 2007-02-23 DK DK07711099.7T patent/DK1994939T3/da active
- 2007-02-23 AU AU2007219568A patent/AU2007219568B2/en not_active Ceased
- 2007-02-23 MX MX2008011140A patent/MX2008011140A/es active IP Right Grant
- 2007-02-23 EP EP07711099A patent/EP1994939B1/en active Active
- 2007-02-23 WO PCT/CU2007/000005 patent/WO2007098715A1/es not_active Ceased
- 2007-02-23 KR KR1020087023744A patent/KR101462077B1/ko active Active
- 2007-02-23 CN CN2007800140575A patent/CN101426517B/zh active Active
- 2007-02-23 JP JP2008556642A patent/JP5426175B2/ja not_active Expired - Fee Related
- 2007-02-23 ES ES07711099T patent/ES2388879T3/es active Active
- 2007-02-23 BR BRPI0708349A patent/BRPI0708349B8/pt not_active IP Right Cessation
- 2007-02-23 RU RU2008138561/15A patent/RU2465913C2/ru not_active Application Discontinuation
- 2007-02-27 AR ARP070100804A patent/AR059644A1/es unknown
2008
- 2008-09-03 ZA ZA200807600A patent/ZA200807600B/xx unknown
2011
- 2011-06-01 US US13/150,526 patent/US8722626B2/en active Active

Also Published As

Publication number	Publication date
KR20080100378A (ko)	2008-11-17
AU2007219568A1 (en)	2007-09-07
CN101426517A (zh)	2009-05-06
JP2009528302A (ja)	2009-08-06
EP1994939B1 (en)	2012-05-30
RU2465913C2 (ru)	2012-11-10
BRPI0708349A2 (pt)	2011-05-24
BRPI0708349B1 (pt)	2019-04-24
CA2644431A1 (en)	2007-09-07
EP1994939A1 (en)	2008-11-26
JP5426175B2 (ja)	2014-02-26
US20090221512A1 (en)	2009-09-03
CN101426517B (zh)	2013-04-03
MX2008011140A (es)	2008-09-08
US20110230415A1 (en)	2011-09-22
CA2644431C (en)	2016-08-30
US8722626B2 (en)	2014-05-13
BRPI0708349B8 (pt)	2021-05-25
WO2007098715A1 (es)	2007-09-07
RU2008138561A (ru)	2010-04-10
CU23592A1 (es)	2010-11-11
AR059644A1 (es)	2008-04-16
AU2007219568B2 (en)	2012-10-04
EP2368563A1 (en)	2011-09-28
ES2388879T3 (es)	2012-10-19
ZA200807600B (en)	2009-06-24
KR101462077B1 (ko)	2014-11-20

Publication	Publication Date	Title
DK1994939T3 (da)	2012-09-10	Farmaceutisk sammensætning indeholdende GHRP-6 til forebyggelse og eliminering af fibrose og øvrige patologiske deponeringer i væv
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IL197275A0 (en)	2009-12-24	Pharmaceutical compositions of clonazepam and methods of use thereof
IL194404A0 (en)	2009-08-03	Benzyl phenyl glucopyranoside derivatives and pharmaceutical compositions containing the same
IL194242A0 (en)	2009-08-03	Heterocyclic compounds and pharmaceutical compositions containing the same
IL197161A0 (en)	2009-12-24	Derivatives of 4-(n-azacycloalkyl)anilides and compositions containing the same
IL196267A0 (en)	2009-09-22	Indole derivatives and pharmaceutical compositions containing the same
IL194460A0 (en)	2009-08-03	Deazapurine derivatives and pharmaceutical compositions containing the same
IL192640A0 (en)	2009-08-03	Inhibitors of tyrosine kinases and pharmaceutical compositions containing the same
DK2089047T3 (da)	2013-02-18	Sammensætninger og fremgangsmåder til beskyttelse og regenerering af hjerte-væv
IL196465A0 (en)	2009-11-18	Compositions and methods for the treatment of mucositis
DK1962807T3 (da)	2014-11-03	Film-coatet og/eller granuleret calcium-indeholdende forbindelser og anvendelse deraf i farmaceutiske sammensætninger
IL196169A0 (en)	2009-09-22	Bile acid derivatives and pharmaceutical compositions containing the same
IL194546A0 (en)	2009-08-03	Arylaminopyridine derivatives and pharmaceutical compositions containing them
IL190292A (en)	2017-01-31	History of pyridopyrimidinone and their pharmaceutical preparations
IL187257A0 (en)	2008-02-09	Compositions and methods for inhibition of the jak pathway
EP2056835A4 (en)	2013-01-30	PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
BRPI0905715A2 (pt)	2015-07-14	Composição farmacêutica e kit de componentes
IL189781A0 (en)	2008-08-07	Sulphonylpyrrole hydrochloride salts and pharmaceutical compositions containing the same
EP1890677A4 (en)	2013-01-30	PHARMACEUTICAL COMPOSITIONS AND THEIR USE
EP2070919A4 (en)	2010-05-05	SPIROCHINONE COMPOUND AND PHARMACEUTICAL COMPOSITION
MY145406A (en)	2012-02-15	Composition for preventing or treating damages of the mucosa in the gastrointestinal tracts
EP2029132A4 (en)	2011-07-27	ANTIHISTAMINE COMPOSITIONS AND THEIR USE
IL207423A0 (en)	2010-12-30	Amide derivative and pharmaceutical composition containing the same