ZA200807600B - Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue - Google Patents

Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue

Info

Publication number: ZA200807600B
Authority: ZA; South Africa
Prior art keywords: elimanting; fibrosis; tissue; preventing; forms
Prior art date: 2006-02-28

Application number

ZA200807600A

Other languages

English (en)

Inventor

Berlanga Acosta Jorge

Cibrian Vera Danay

Garcia Del Barco Herrera Diana

Guillen Nieto Gerardo Enrique

Suarez Alba Jose

Lopez Mola Ernesto

Selman-Housein Sosa Manuel

Vazquez Castillo Mariela

Original Assignee

Ct L De Ingenieria Genetica Y

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-28

Filing date

2008-09-03

Publication date

2009-06-24

2008-09-03 Application filed by Ct L De Ingenieria Genetica Y filed Critical Ct L De Ingenieria Genetica Y

2009-06-24 Publication of ZA200807600B publication Critical patent/ZA200807600B/xx

Links

WZHKXNSOCOQYQX-FUAFALNISA-N (2s)-6-amino-2-[[(2r)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CN=CN1 WZHKXNSOCOQYQX-FUAFALNISA-N 0.000 title 1
206010016654 Fibrosis Diseases 0.000 title 1
230000004761 fibrosis Effects 0.000 title 1
108010015153 growth hormone releasing hexapeptide Proteins 0.000 title 1
230000001575 pathological effect Effects 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Endocrinology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Zoology (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

ZA200807600A 2006-02-28 2008-09-03 Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue ZA200807600B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CU20060048A CU23592A1 (es)	2006-02-28	2006-02-28	Método para prevenir y eliminar las fibrosis y otras formas de depósito patológico en los tejidos aplicando el péptido secretagogo ghrp-6

Publications (1)

Publication Number	Publication Date
ZA200807600B true ZA200807600B (en)	2009-06-24

Family

ID=37964643

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200807600A ZA200807600B (en)	2006-02-28	2008-09-03	Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue

Country Status (16)

Country	Link
US (2)	US20090221512A1 (da)
EP (2)	EP2368563A1 (da)
JP (1)	JP5426175B2 (da)
KR (1)	KR101462077B1 (da)
CN (1)	CN101426517B (da)
AR (1)	AR059644A1 (da)
AU (1)	AU2007219568B2 (da)
BR (1)	BRPI0708349B8 (da)
CA (1)	CA2644431C (da)
CU (1)	CU23592A1 (da)
DK (1)	DK1994939T3 (da)
ES (1)	ES2388879T3 (da)
MX (1)	MX2008011140A (da)
RU (1)	RU2465913C2 (da)
WO (1)	WO2007098715A1 (da)
ZA (1)	ZA200807600B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8592377B2 (en)	2007-03-28	2013-11-26	President And Fellows Of Harvard College	Stitched polypeptides
ES2711526T3 (es)	2010-08-13	2019-05-06	Aileron Therapeutics Inc	Macrociclos peptidomiméticos
TW201806968A (zh)	2011-10-18	2018-03-01	艾利倫治療公司	擬肽巨環化合物
EP2819688A4 (en)	2012-02-15	2015-10-28	Aileron Therapeutics Inc	TRIAZOL AND THIOETHER-COUPLED PEPTIDOMIMETIC MACROCYCLES
BR112014020103A2 (pt)	2012-02-15	2018-10-09	Aileron Therapeutics, Inc.	macrociclos peptidomiméticos
KR101667383B1 (ko) *	2012-03-28	2016-10-18	주식회사 인코스팜	비오틴이 결합된 ｈｅｘａｐｅｐｔｉｄｅ-２ 유도체 및 이의 용도
WO2014071241A1 (en)	2012-11-01	2014-05-08	Aileron Therapeutics, Inc.	Disubstituted amino acids and methods of preparation and use thereof
KR102051433B1 (ko) *	2013-08-27	2020-01-08	(주)네오팜	근육 분화 촉진 및 근육 강화용 조성물 및 외용제
US9119832B2 (en) *	2014-02-05	2015-09-01	The Regents Of The University Of California	Methods of treating mild brain injury
EP3197478A4 (en)	2014-09-24	2018-05-30	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
WO2016154058A1 (en)	2015-03-20	2016-09-29	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
FR3034662B1 (fr) *	2015-04-10	2020-08-28	Isp Investments Inc	Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane
CN106730414B (zh) *	2015-12-30	2017-10-10	南京中硼联康医疗科技有限公司	用于消除β淀粉样蛋白的中子捕获治疗系统
KR102394643B1 (ko) *	2016-10-18	2022-05-09	(주)아모레퍼시픽	후발효차 유래의 신규한 캄페롤계 화합물을 포함하는 인지기능 개선용 조성물
CN109908331A (zh) *	2019-04-30	2019-06-21	青岛大学附属医院	海沙瑞林在制备保护肾脏缺血再灌注损伤药物/药物组合物中的应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4411890A (en) *	1981-04-14	1983-10-25	Beckman Instruments, Inc.	Synthetic peptides having pituitary growth hormone releasing activity
TW432073B (en) *	1995-12-28	2001-05-01	Pfizer	Pyrazolopyridine compounds
CA2395996A1 (en) *	1999-12-28	2001-07-05	Kaken Pharmaceutical Co., Ltd.	Neuroprotective drug
CU23157A1 (es) *	2001-01-03	2006-07-18	Ct Ingenieria Genetica Biotech	COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL
WO2003047624A1 (fr) *	2001-12-07	2003-06-12	Kaken Pharmaceutical Co., Ltd.	Inhibiteur de migration cellulaire
TWI331922B (en) *	2002-08-09	2010-10-21	Ipsen Pharma Sas	Growth hormone releasing peptides
JP4467518B2 (ja) *	2003-04-30	2010-05-26	賢治寒川	肝障害予防治療剤
JP2005239712A (ja) *	2004-01-30	2005-09-08	Kaken Pharmaceut Co Ltd	神経突起伸展剤
US20090149512A1 (en) *	2004-05-14	2009-06-11	Novo Nordisk A/S	Use of Ghrelin Antagonists to the Treatment of Certain CNS Diseases

2006
- 2006-02-28 CU CU20060048A patent/CU23592A1/es unknown
2007
- 2007-02-23 EP EP11170318A patent/EP2368563A1/en not_active Withdrawn
- 2007-02-23 US US12/281,018 patent/US20090221512A1/en not_active Abandoned
- 2007-02-23 CA CA2644431A patent/CA2644431C/en active Active
- 2007-02-23 DK DK07711099.7T patent/DK1994939T3/da active
- 2007-02-23 AU AU2007219568A patent/AU2007219568B2/en not_active Ceased
- 2007-02-23 MX MX2008011140A patent/MX2008011140A/es active IP Right Grant
- 2007-02-23 EP EP07711099A patent/EP1994939B1/en active Active
- 2007-02-23 WO PCT/CU2007/000005 patent/WO2007098715A1/es not_active Ceased
- 2007-02-23 KR KR1020087023744A patent/KR101462077B1/ko active Active
- 2007-02-23 CN CN2007800140575A patent/CN101426517B/zh active Active
- 2007-02-23 JP JP2008556642A patent/JP5426175B2/ja not_active Expired - Fee Related
- 2007-02-23 ES ES07711099T patent/ES2388879T3/es active Active
- 2007-02-23 BR BRPI0708349A patent/BRPI0708349B8/pt not_active IP Right Cessation
- 2007-02-23 RU RU2008138561/15A patent/RU2465913C2/ru not_active Application Discontinuation
- 2007-02-27 AR ARP070100804A patent/AR059644A1/es unknown
2008
- 2008-09-03 ZA ZA200807600A patent/ZA200807600B/xx unknown
2011
- 2011-06-01 US US13/150,526 patent/US8722626B2/en active Active

Also Published As

Publication number	Publication date
KR20080100378A (ko)	2008-11-17
AU2007219568A1 (en)	2007-09-07
CN101426517A (zh)	2009-05-06
JP2009528302A (ja)	2009-08-06
EP1994939B1 (en)	2012-05-30
RU2465913C2 (ru)	2012-11-10
BRPI0708349A2 (pt)	2011-05-24
BRPI0708349B1 (pt)	2019-04-24
CA2644431A1 (en)	2007-09-07
EP1994939A1 (en)	2008-11-26
JP5426175B2 (ja)	2014-02-26
US20090221512A1 (en)	2009-09-03
CN101426517B (zh)	2013-04-03
MX2008011140A (es)	2008-09-08
US20110230415A1 (en)	2011-09-22
CA2644431C (en)	2016-08-30
US8722626B2 (en)	2014-05-13
BRPI0708349B8 (pt)	2021-05-25
WO2007098715A1 (es)	2007-09-07
RU2008138561A (ru)	2010-04-10
CU23592A1 (es)	2010-11-11
AR059644A1 (es)	2008-04-16
DK1994939T3 (da)	2012-09-10
AU2007219568B2 (en)	2012-10-04
EP2368563A1 (en)	2011-09-28
ES2388879T3 (es)	2012-10-19
KR101462077B1 (ko)	2014-11-20

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