DK200301267A - Inhibitor formonoaminoptagelse - Google Patents

Inhibitor formonoaminoptagelse Download PDF

Info

Publication number: DK200301267A
Authority: DK; Denmark
Prior art keywords: uptake; formonoamine; inhibitor; compound; formula
Prior art date: 2001-03-06

Application number

DK200301267A

Other languages

English (en)

Inventor

Edward Louis Mattiuz

John-Michael Sauer

William Joe Wheeler

David Taiwai Wong

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-06

Filing date

2003-09-04

Publication date

2003-11-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23045157&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK200301267(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-09-04 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2003-11-06 Publication of DK200301267A publication Critical patent/DK200301267A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Hematology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Immunology (AREA)
Otolaryngology (AREA)
Gynecology & Obstetrics (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

Description

Patentkrav: 1. Forbindelse med formlen I:

eller et farmaceutisk acceptabelt salt deraf. 2. Forbindelsen R-(-)-N-methyl-3-({2-methyl-4-hydroxyphenyl)oxy)-3-phenyl-1-aminopropanhydrochlorid. 3. Farmaceutisk formulering, der omfatter en forbindelse med formlen I:

eller et farmaceutisk acceptabelt salt deraf i forbindelse med en farmaceutisk acceptabel bærer, et farmaceutisk acceptabelt fortyndingsmiddel eller en farmaceutisk acceptabel excipiens. 4. Farmaceutisk formulering ifølge krav 3, hvori forbindelsen med formlen I er R-(-)-N-methyl-3-((2-methyl-4-hydroxyphenyl)oxy)-3-phenyl- 1 -aminopropanhydrochlorid. 5. Fremgangsmåde til inhibering af optagelsen af norepinephrin og serotonin i pattedyr, der omfatter at indgive en farmaceutisk effektiv mængde af en forbindelse med formlen I:

eller et farmaceutisk acceptabelt salt deraf til et pattedyr med behov for en sådan irhibering. 6, Fremgangsmåde ifølge krav 5, hvori forbindelsen med formlen I indgives systemisk.

DK200301267A 2001-03-06 2003-09-04 Inhibitor formonoaminoptagelse DK200301267A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US27373001P	2001-03-06	2001-03-06
PCT/US2002/003385 WO2002070457A1 (en)	2001-03-06	2002-02-20	Inhibitor of monoamine uptake

Publications (1)

Publication Number	Publication Date
DK200301267A true DK200301267A (da)	2003-11-06

Family

ID=23045157

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK200301267A DK200301267A (da)	2001-03-06	2003-09-04	Inhibitor formonoaminoptagelse

Country Status (35)

Country	Link
US (2)	US20040082666A1 (da)
EP (1)	EP1379492B1 (da)
JP (1)	JP2004525912A (da)
KR (1)	KR20030092012A (da)
CN (1)	CN1229331C (da)
AP (1)	AP2003002855A0 (da)
AT (2)	ATE396170T1 (da)
AU (1)	AU2002245385B2 (da)
BR (1)	BR0207716A (da)
CA (1)	CA2440161A1 (da)
CH (1)	CH695982A5 (da)
CZ (1)	CZ20032380A3 (da)
DE (1)	DE60226715D1 (da)
DK (1)	DK200301267A (da)
EA (1)	EA005768B1 (da)
EC (1)	ECSP034760A (da)
EE (1)	EE200300419A (da)
ES (2)	ES2201942B2 (da)
FI (1)	FI20031191L (da)
GB (1)	GB2389851B (da)
HR (1)	HRP20030710A2 (da)
HU (1)	HUP0303341A3 (da)
IL (1)	IL157779A0 (da)
LT (1)	LT5143B (da)
LU (1)	LU91038B1 (da)
LV (1)	LV13119B (da)
NO (1)	NO20033921L (da)
NZ (1)	NZ527431A (da)
OA (1)	OA12494A (da)
PL (1)	PL363840A1 (da)
SE (1)	SE526598C2 (da)
SK (1)	SK10632003A3 (da)
TR (1)	TR200705146T1 (da)
WO (1)	WO2002070457A1 (da)
ZA (1)	ZA200306882B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR200705146T1 (tr) *	2001-03-06	2008-02-21	Eli Lilly And Company	Monoamin Yükselmesinin Engellenmesi
CA2536161A1 (en) *	2003-08-27	2005-03-10	Eli Lilly And Company	Treatment of pervasive developmental disorders with norepinephrine reuptake inhibitors
ATE399557T1 (de) *	2003-12-12	2008-07-15	Lilly Co Eli	Selektive norepinephrin-wiederaufnahmehemmer zur behandlung von hitzewallungen
WO2011027359A2 (en) *	2009-07-30	2011-03-10	Matrix Laboratories Ltd	Novel process for the preparation of 4-hydroxy atomoxetine
WO2012020418A1 (en)	2010-08-12	2012-02-16	Matrix Laboratories Ltd	Novel polymorphs of 4-hydroxy atomoxetine hydrochloride
DE102013022397A1 (de)	2013-12-19	2016-07-07	Metrax Gmbh	Vorrichtung zur Unterstützung eines Ersthelfers bei der Herzdruckmassage
GR1008819B (el)	2015-05-22	2016-08-01	Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων	Φαρμακευτικο σκευασμα που περιλαμβανει ατομοξετινη και μεθοδος παρασκευης αυτου
CN107935848B (zh) *	2017-11-21	2020-12-22	中国农业科学院兰州畜牧与兽药研究所	一种六茜素衍生物及其制备方法和应用
KR20210084481A (ko) *	2018-10-31	2021-07-07	애프니메드, 인코포레이티드 (델라웨어)	수면 무호흡증의 치료 방법 및 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4314081A (en) *	1974-01-10	1982-02-02	Eli Lilly And Company	Arloxyphenylpropylamines
US4194009A (en)	1974-01-10	1980-03-18	Eli Lilly And Company	Aryloxyphenylpropylamines for obtaining a psychotropic effect
US4018895A (en)	1974-01-10	1977-04-19	Eli Lilly And Company	Aryloxyphenylpropylamines in treating depression
FR2432500A1 (fr) *	1978-02-24	1980-02-29	Roussel Uclaf	Nouveaux derives de la benzene propanamine et leurs sels, procede de preparation et application a titre de medicaments
US5112619A (en) *	1985-11-12	1992-05-12	Eli Lilly And Company	Orally administerable sustained release pharmaceutical formulation
US4956388A (en)	1986-12-22	1990-09-11	Eli Lilly And Company	3-aryloxy-3-substituted propanamines
ZA885824B (en) *	1987-08-14	1989-04-26	Merrell Dow Pharma	Novel antidepressants
AU642582B2 (en) *	1991-02-25	1993-10-21	Eli Lilly And Company	Treatment of lower urinary tract disorders
TW514634B (en)	1997-10-14	2002-12-21	Lilly Co Eli	Process to make chiral compounds
WO2000058262A1 (en)	1999-03-29	2000-10-05	Eli Lilly And Company	Stereospecific method for preparing tomoxetine and intermediates thereof
JP2002541235A (ja)	1999-04-09	2002-12-03	イーライ・リリー・アンド・カンパニー	３−アリールオキシ−３−アリールプロピルアミン及びその中間体の製造方法
PL366119A1 (en) *	2000-11-15	2005-01-24	Eli Lilly And Company	Treatment of anxiety disorders
TR200705146T1 (tr) *	2001-03-06	2008-02-21	Eli Lilly And Company	Monoamin Yükselmesinin Engellenmesi

2002
- 2002-02-20 TR TR2007/05146T patent/TR200705146T1/xx unknown
- 2002-02-20 AP APAP/P/2003/002855A patent/AP2003002855A0/en unknown
- 2002-02-20 GB GB0323169A patent/GB2389851B/en not_active Expired - Fee Related
- 2002-02-20 FI FI20031191A patent/FI20031191L/fi not_active IP Right Cessation
- 2002-02-20 SK SK1063-2003A patent/SK10632003A3/sk unknown
- 2002-02-20 IL IL15777902A patent/IL157779A0/xx unknown
- 2002-02-20 CN CNB028060253A patent/CN1229331C/zh not_active Ceased
- 2002-02-20 OA OA1200300215A patent/OA12494A/en unknown
- 2002-02-20 EE EEP200300419A patent/EE200300419A/xx unknown
- 2002-02-20 LU LU91038A patent/LU91038B1/fr active
- 2002-02-20 JP JP2002569778A patent/JP2004525912A/ja not_active Ceased
- 2002-02-20 AU AU2002245385A patent/AU2002245385B2/en not_active Ceased
- 2002-02-20 ES ES200350052A patent/ES2201942B2/es not_active Expired - Fee Related
- 2002-02-20 AT AT02713538T patent/ATE396170T1/de not_active IP Right Cessation
- 2002-02-20 HR HR20030710A patent/HRP20030710A2/hr not_active Application Discontinuation
- 2002-02-20 CA CA002440161A patent/CA2440161A1/en not_active Abandoned
- 2002-02-20 DE DE60226715T patent/DE60226715D1/de not_active Revoked
- 2002-02-20 KR KR10-2003-7011635A patent/KR20030092012A/ko not_active Ceased
- 2002-02-20 EP EP02713538A patent/EP1379492B1/en not_active Revoked
- 2002-02-20 EA EA200300978A patent/EA005768B1/ru not_active IP Right Cessation
- 2002-02-20 WO PCT/US2002/003385 patent/WO2002070457A1/en not_active Ceased
- 2002-02-20 BR BR0207716-7A patent/BR0207716A/pt not_active IP Right Cessation
- 2002-02-20 CZ CZ20032380A patent/CZ20032380A3/cs unknown
- 2002-02-20 AT AT0904202A patent/AT414238B/de not_active IP Right Cessation
- 2002-02-20 NZ NZ527431A patent/NZ527431A/en unknown
- 2002-02-20 PL PL02363840A patent/PL363840A1/xx not_active Application Discontinuation
- 2002-02-20 ES ES02713538T patent/ES2305221T3/es not_active Expired - Lifetime
- 2002-02-20 CH CH01522/03A patent/CH695982A5/de not_active IP Right Cessation
- 2002-02-20 HU HU0303341A patent/HUP0303341A3/hu unknown
- 2002-02-20 US US10/468,553 patent/US20040082666A1/en not_active Abandoned
2003
- 2003-08-11 LT LT2003075A patent/LT5143B/lt unknown
- 2003-09-02 EC EC2003004760A patent/ECSP034760A/es unknown
- 2003-09-03 ZA ZA200306882A patent/ZA200306882B/en unknown
- 2003-09-03 SE SE0302361A patent/SE526598C2/sv not_active IP Right Cessation
- 2003-09-04 DK DK200301267A patent/DK200301267A/da not_active Application Discontinuation
- 2003-09-04 NO NO20033921A patent/NO20033921L/no not_active Application Discontinuation
- 2003-09-10 LV LVP-03-100A patent/LV13119B/en unknown
2005
- 2005-05-09 US US11/125,348 patent/US7384983B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CH695982A5 (de)	2006-11-15
CN1494526A (zh)	2004-05-05
GB2389851B (en)	2005-05-25
PL363840A1 (pl)	2004-11-29
TR200705146T1 (tr)	2008-02-21
FI20031191A7 (fi)	2003-08-25
EE200300419A (et)	2004-02-16
EP1379492B1 (en)	2008-05-21
OA12494A (en)	2006-05-24
AT414238B (de)	2006-10-15
US20040082666A1 (en)	2004-04-29
ZA200306882B (en)	2004-12-03
LV13119B (en)	2004-06-20
LT5143B (lt)	2004-06-25
NZ527431A (en)	2005-05-27
EA005768B1 (ru)	2005-06-30
US7384983B2 (en)	2008-06-10
ES2201942A1 (es)	2004-03-16
LU91038B1 (fr)	2003-09-11
FI20031191L (fi)	2003-08-25
EP1379492A1 (en)	2004-01-14
LT2003075A (en)	2004-03-25
SE526598C2 (sv)	2005-10-18
ES2201942B2 (es)	2004-12-16
JP2004525912A (ja)	2004-08-26
NO20033921D0 (no)	2003-09-04
BR0207716A (pt)	2004-03-23
IL157779A0 (en)	2004-03-28
ECSP034760A (es)	2003-10-28
WO2002070457A1 (en)	2002-09-12
CA2440161A1 (en)	2002-09-12
SE0302361D0 (sv)	2003-09-03
AU2002245385B2 (en)	2007-01-18
HUP0303341A3 (en)	2007-03-28
WO2002070457A8 (en)	2004-06-03
CZ20032380A3 (en)	2004-03-17
GB0323169D0 (en)	2003-11-05
ATE396170T1 (de)	2008-06-15
SK10632003A3 (sk)	2004-06-08
AP2003002855A0 (en)	2003-08-20
SE0302361L (sv)	2003-09-03
US20050209341A1 (en)	2005-09-22
ES2305221T3 (es)	2008-11-01
HRP20030710A2 (en)	2004-08-31
HUP0303341A2 (hu)	2004-01-28
KR20030092012A (ko)	2003-12-03
EA200300978A1 (ru)	2004-02-26
GB2389851A (en)	2003-12-24
ATA90422002A (de)	2006-01-15
DE60226715D1 (de)	2008-07-03
CN1229331C (zh)	2005-11-30
NO20033921L (no)	2003-11-05

Legal Events

Date	Code	Title	Description
2008-09-29	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
EP1022026A3 (en)	2002-04-10	Pharmaceutical compositions for treating nitrate-induced tolerance
UY26512A1 (es)	2001-07-31	Inhibidores no peptídicos de la unión celúlar dependiente de vla - 4 útiles en el tratamiento de enfermedades inflamatorias, autoinmunes y respiratorias
ATE556061T1 (de)	2012-05-15	Therapeutisches oder prophylaktisches mittel gegen multiple sklerose
EA200200778A1 (ru)	2003-06-26	СПОСОБ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ГЕПАТИТА С В ОРГАНИЗМЕ ХОЗЯИНА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ПРОТИВ ФЛАВИВИРУСА, СОЕДИНЕНИЕ ФОРМУЛЫ Ib - АКТИВНЫЙ АГЕНТ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ ИНФЕКЦИИ ГЕПАТИТА С ИЛИ ФЛАВИВИРУСА (ВАРИАНТЫ)
DK1487829T3 (da)	2008-02-11	Thiadizolylpiperazinderivater, der er nyttige til behandling eller forebyggelse af smerte
NO20032510L (no)	2003-06-03	Organiske forbindelser
RU2014149337A (ru)	2016-06-27	Аналоги этомидата с улучшенными фармакокинетическими и фармакодинамическими свойствами
IT1271495B (it)	1997-05-30	Composizione farmaceutica contenente 3-2 (dimetilammino) etil-n-metil-1h-indol-5-metansolfonammide, relativo procedimento di preparazione e impiego della stessa nel trattamento di mammiferi
KR950016745A (ko)	1995-07-20	생리증상의 치료방법 및 이를 위한 조성물
EA200500080A1 (ru)	2005-06-30	Дозированная форма прамипексола, принимаемая один раз в день
RU2001135826A (ru)	2003-08-20	Новое применение соединений в качестве антибактериальных средств
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