DK2003122T3 - Fremgangsmåde til fremstilling af 5-hydroxy-1-methylhydantoin - Google Patents

Fremgangsmåde til fremstilling af 5-hydroxy-1-methylhydantoin

Info

Publication number: DK2003122T3
Authority: DK; Denmark
Prior art keywords: methylhydantoin; hydroxy; preparation; methylimidazolidin; hydrolyzed
Prior art date: 2002-04-10

Application number

DK08015840.5T

Other languages

English (en)

Inventor

Kaoru Okamoto

Naoharu Nishimura

Akira Ishii

Original Assignee

Nippon Zoki Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-10

Filing date

2003-04-09

Publication date

2012-02-20

2003-04-09 Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co

2012-02-20 Application granted granted Critical

2012-02-20 Publication of DK2003122T3 publication Critical patent/DK2003122T3/da

Links

UPSFNXFLBMJUQW-UHFFFAOYSA-N 5-hydroxy-1-methylimidazolidine-2,4-dione Chemical compound CN1C(O)C(=O)NC1=O UPSFNXFLBMJUQW-UHFFFAOYSA-N 0.000 title 2
RHYBFKMFHLPQPH-UHFFFAOYSA-N N-methylhydantoin Chemical compound CN1CC(=O)NC1=O RHYBFKMFHLPQPH-UHFFFAOYSA-N 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Obesity (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Liquid Crystal Substances (AREA)

DK08015840.5T 2002-04-10 2003-04-09 Fremgangsmåde til fremstilling af 5-hydroxy-1-methylhydantoin DK2003122T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2002107533		2002-04-10
EP03745985A EP1493734B1 (en)	2002-04-10	2003-04-09	Novel crystal form of 5-hydroxy-1-methylhydantoin

Publications (1)

Publication Number	Publication Date
DK2003122T3 true DK2003122T3 (da)	2012-02-20

Family

ID=28786466

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK08015840.5T DK2003122T3 (da)	2002-04-10	2003-04-09	Fremgangsmåde til fremstilling af 5-hydroxy-1-methylhydantoin
DK03745985.6T DK1493734T3 (da)	2002-04-10	2003-04-09	Ny krystalform af 5-hydroxy-1-methylhydantoin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK03745985.6T DK1493734T3 (da)	2002-04-10	2003-04-09	Ny krystalform af 5-hydroxy-1-methylhydantoin

Country Status (12)

Country	Link
US (2)	US7569701B2 (da)
EP (2)	EP2003122B1 (da)
JP (3)	JP4347598B2 (da)
KR (2)	KR20040099357A (da)
CN (1)	CN1291978C (da)
AT (2)	ATE536346T1 (da)
AU (2)	AU2003236013B2 (da)
CA (2)	CA2700679C (da)
DK (2)	DK2003122T3 (da)
ES (2)	ES2377583T3 (da)
TW (1)	TWI353979B (da)
WO (1)	WO2003084934A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI353979B (en) *	2002-04-10	2011-12-11	Nippon Zoki Pharmaceutical Co	Novel crystal form of 5-hydroxy-1-methylhydantoin
US20060241163A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (S)-hydantoin derivative
US20060241162A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (R)-hydantoin derivative
DK1961420T3 (da) *	2005-12-16	2012-08-27	Sanwa Kagaku Kenkyusho Co	Middel til forebyggelse og behandling af akut nyresvigt
JP5546198B2 (ja)	2009-10-09	2014-07-09	キヤノン株式会社	固体撮像装置
KR102311915B1 (ko)	2014-02-26	2021-10-13	니폰 조키 세야쿠 가부시키가이샤	만성 신장병의 진행 억제 또는 개선제
EP4364734A4 (en) *	2021-07-02	2025-07-09	Kyongbo Pharm Co Ltd	VETERINARY PHARMACEUTICAL COMPOSITION COMPRISING A 5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE COMPOUND AS ACTIVE INGREDIENT

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JPS61212567A (ja)	1985-03-18	1986-09-20	Showa Denko Kk	ヒダントイン製造における着色防止法
JPS61211567A (ja)	1985-03-18	1986-09-19	Hitachi Electronics Eng Co Ltd	ボ−ルネジ・ナツト支承装置
JPH0623102B2 (ja)	1985-08-22	1994-03-30	日本臓器製薬株式会社	脂質低下剤
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JPS6475473A (en) *	1987-09-17	1989-03-22	Nippon Zoki Pharmaceutical Co	Production of hydantoin derivative
JPH01299276A (ja)	1988-05-26	1989-12-04	Nippon Zoki Pharmaceut Co Ltd	ヒダントイン誘導体の製造方法
JP2544183B2 (ja)	1988-07-29	1996-10-16	日本臓器製薬株式会社	新規パラバン酸誘導体及び該化合物を有効成分として含有する医薬組成物
JP2678499B2 (ja) *	1989-08-09	1997-11-17	日本臓器製薬株式会社	尿毒症毒素低下剤
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JPH04342556A (ja)	1991-01-23	1992-11-30	Nitto Chem Ind Co Ltd	テトラシアノキノジメタン複塩とその製法
GB9119001D0 (en)	1991-09-05	1991-10-23	Ici Plc	Pharmaceutical agents
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JP3259476B2 (ja) *	1993-09-30	2002-02-25	日本ゼオン株式会社	シクロオレフィン系開環重合体水素添加物の製造方法
JPH07149732A (ja)	1993-10-06	1995-06-13	Showa Denko Kk	５−アリールヒダントイン化合物およびその誘導体の製造方法
US5681843A (en)	1994-12-20	1997-10-28	Nippon Zoki Pharmaceutical Co., Ltd.	Parabanic acid derivatives
JPH08269018A (ja)	1995-03-31	1996-10-15	Showa Denko Kk	５−置換ヒダントイン化合物の製造方法
JP3072463B2 (ja)	1995-06-19	2000-07-31	日進医療器株式会社	起立用車椅子
US6197806B1 (en)	1995-12-20	2001-03-06	Nippon Zoki Pharmaceutical Co., Ltd.	Eliminating agent for activated oxygen and free radicals
JP3836203B2 (ja)	1995-12-20	2006-10-25	日本臓器製薬株式会社	活性酸素・フリーラジカル消去剤
JPH1072446A (ja)	1996-06-24	1998-03-17	Sumitomo Chem Co Ltd	１−置換−ヒダントイン類の製造法
JPH10182460A (ja)	1996-12-27	1998-07-07	Nippon Zoki Pharmaceut Co Ltd	３−デオキシグルコソン生成阻害剤
JP2000031488A (ja) *	1997-08-26	2000-01-28	Semiconductor Energy Lab Co Ltd	半導体装置およびその作製方法
JPH11171843A (ja)	1997-11-18	1999-06-29	Mitsubishi Rayon Co Ltd	嵩密度の大きい［ｓ，ｓ］−エチレンジアミン−ｎ，ｎ’−ジコハク酸の結晶およびその取得方法
AU754989B2 (en)	1998-11-16	2002-11-28	Nippon Zoki Pharmaceutical Co., Ltd.	A therapeutic agent for intractable vasculitis
JP4374407B2 (ja) *	1998-11-27	2009-12-02	財団法人相模中央化学研究所	３−イソクロマノン誘導体を製造する方法
JP4711523B2 (ja)	2001-02-13	2011-06-29	日本臓器製薬株式会社	低アルブミン血症改善剤
TWI353979B (en) *	2002-04-10	2011-12-11	Nippon Zoki Pharmaceutical Co	Novel crystal form of 5-hydroxy-1-methylhydantoin
JP2004123735A (ja)	2002-09-11	2004-04-22	Nippon Zoki Pharmaceut Co Ltd	光学活性（ｓ）−ヒダントイン誘導体
JP2004123736A (ja)	2002-09-11	2004-04-22	Nippon Zoki Pharmaceut Co Ltd	光学活性（ｒ）−ヒダントイン誘導体
DE102004005179B4 (de)	2004-02-02	2006-07-13	Wobben, Aloys, Dipl.-Ing.	Windenergieanlage
US20060241163A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (S)-hydantoin derivative
US20060241162A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (R)-hydantoin derivative

2003
- 2003-03-31 TW TW092107234A patent/TWI353979B/zh not_active IP Right Cessation
- 2003-04-09 DK DK08015840.5T patent/DK2003122T3/da active
- 2003-04-09 DK DK03745985.6T patent/DK1493734T3/da active
- 2003-04-09 KR KR10-2004-7015029A patent/KR20040099357A/ko not_active Ceased
- 2003-04-09 US US10/508,496 patent/US7569701B2/en not_active Expired - Fee Related
- 2003-04-09 EP EP08015840A patent/EP2003122B1/en not_active Expired - Lifetime
- 2003-04-09 ES ES08015840T patent/ES2377583T3/es not_active Expired - Lifetime
- 2003-04-09 EP EP03745985A patent/EP1493734B1/en not_active Expired - Lifetime
- 2003-04-09 CN CNB038080893A patent/CN1291978C/zh not_active Expired - Fee Related
- 2003-04-09 ES ES03745985T patent/ES2367483T3/es not_active Expired - Lifetime
- 2003-04-09 CA CA2700679A patent/CA2700679C/en not_active Expired - Fee Related
- 2003-04-09 WO PCT/JP2003/004497 patent/WO2003084934A1/ja not_active Ceased
- 2003-04-09 AT AT08015840T patent/ATE536346T1/de active
- 2003-04-09 KR KR1020097016830A patent/KR101071796B1/ko not_active Expired - Fee Related
- 2003-04-09 CA CA2479549A patent/CA2479549C/en not_active Expired - Fee Related
- 2003-04-09 AT AT03745985T patent/ATE515499T1/de not_active IP Right Cessation
- 2003-04-09 AU AU2003236013A patent/AU2003236013B2/en not_active Ceased
- 2003-04-09 JP JP2003105721A patent/JP4347598B2/ja not_active Expired - Lifetime
2008
- 2008-06-23 JP JP2008162967A patent/JP5202129B2/ja not_active Expired - Lifetime
2009
- 2009-06-19 JP JP2009145936A patent/JP2009235088A/ja active Pending
- 2009-07-07 US US12/498,967 patent/US7858806B2/en not_active Expired - Fee Related
- 2009-08-14 AU AU2009208156A patent/AU2009208156B2/en not_active Ceased

Also Published As

Publication number	Publication date
KR20090091366A (ko)	2009-08-27
CN1646498A (zh)	2005-07-27
EP2003122A3 (en)	2009-01-07
CA2700679A1 (en)	2003-10-16
EP2003122B1 (en)	2011-12-07
CN1291978C (zh)	2006-12-27
JP2004002376A (ja)	2004-01-08
KR20040099357A (ko)	2004-11-26
EP1493734A4 (en)	2006-07-05
ATE515499T1 (de)	2011-07-15
US20050143437A1 (en)	2005-06-30
DK1493734T3 (da)	2011-10-03
ES2377583T3 (es)	2012-03-29
ES2367483T3 (es)	2011-11-03
AU2003236013B2 (en)	2009-05-28
TW200306307A (en)	2003-11-16
US7569701B2 (en)	2009-08-04
KR101071796B1 (ko)	2011-10-11
CA2479549C (en)	2012-06-12
ATE536346T1 (de)	2011-12-15
JP2008266353A (ja)	2008-11-06
JP2009235088A (ja)	2009-10-15
CA2479549A1 (en)	2003-10-16
US7858806B2 (en)	2010-12-28
CA2700679C (en)	2012-09-04
WO2003084934A1 (en)	2003-10-16
AU2003236013A1 (en)	2003-10-20
EP2003122A2 (en)	2008-12-17
JP4347598B2 (ja)	2009-10-21
EP1493734B1 (en)	2011-07-06
EP1493734A1 (en)	2005-01-05
AU2009208156A1 (en)	2009-09-03
US20090270634A1 (en)	2009-10-29
AU2009208156B2 (en)	2012-01-19
JP5202129B2 (ja)	2013-06-05
TWI353979B (en)	2011-12-11

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DE50310977D1 (de)	2009-02-05	Kompaktiertes menthol
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AU2003238198A1 (en)	2003-12-31	Method for producing 4,6-dichloro-5-fluoropyrimidine