DK2062897T3 - Demethylering af 14-hydroxysubstituerede alkaloidderivater - Google Patents
Demethylering af 14-hydroxysubstituerede alkaloidderivaterInfo
- Publication number
- DK2062897T3 DK2062897T3 DK08169873.0T DK08169873T DK2062897T3 DK 2062897 T3 DK2062897 T3 DK 2062897T3 DK 08169873 T DK08169873 T DK 08169873T DK 2062897 T3 DK2062897 T3 DK 2062897T3
- Authority
- DK
- Denmark
- Prior art keywords
- demethylation
- hydroxy
- alkaloid derivatives
- substituted
- substituted alkaloid
- Prior art date
Links
- 150000003797 alkaloid derivatives Chemical class 0.000 title 1
- 230000017858 demethylation Effects 0.000 title 1
- 238000010520 demethylation reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07121537A EP2062896A1 (en) | 2007-11-26 | 2007-11-26 | Demethylation of 14-hydroxy substituted alkaloid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2062897T3 true DK2062897T3 (da) | 2012-10-15 |
Family
ID=39472812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK08169873.0T DK2062897T3 (da) | 2007-11-26 | 2008-11-25 | Demethylering af 14-hydroxysubstituerede alkaloidderivater |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7619088B2 (da) |
| EP (2) | EP2062896A1 (da) |
| CA (2) | CA2640316A1 (da) |
| DK (1) | DK2062897T3 (da) |
| ES (1) | ES2391223T3 (da) |
| PL (1) | PL2062897T3 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8158793B2 (en) * | 2007-11-26 | 2012-04-17 | Siegfried Ltd. | Demethylation of 14-hydroxy substituted alkaloid derivatives |
| EP2477984B1 (en) * | 2009-09-16 | 2016-08-03 | Monash University | A method for the n-demethylation of n-methyl heterocycles |
| GB201313915D0 (en) * | 2013-08-02 | 2013-09-18 | Johnson Matthey Plc | Process |
| WO2021132637A1 (ja) * | 2019-12-27 | 2021-07-01 | 日本ケミファ株式会社 | 環状二級アミンの製造方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB975601A (en) | 1961-11-28 | 1964-11-18 | Edinburgh Pharmaceutical Ind L | Derivatives of 14-hydroxynorcodeine and their production |
| US3342824A (en) | 1964-12-07 | 1967-09-19 | Lilly Co Eli | Normorphines |
| GB1179479A (en) | 1967-06-20 | 1970-01-28 | Reckitt & Sons Ltd | Derivatives of Thebaine |
| US4141897A (en) * | 1976-12-20 | 1979-02-27 | Research Corporation | N-dealkylation of N-alkyl-14-hydroxymorphinans and derivatives thereof |
| GB8711558D0 (en) | 1987-05-15 | 1987-06-17 | Reckitt & Colmann Prod Ltd | Derivative of codeine |
| WO2006084389A1 (de) * | 2005-02-11 | 2006-08-17 | Cilag Ltd. | Verfahren zur reinigung von noroxymorphon-verbindungen |
-
2007
- 2007-11-26 EP EP07121537A patent/EP2062896A1/en not_active Withdrawn
-
2008
- 2008-10-02 CA CA002640316A patent/CA2640316A1/en not_active Abandoned
- 2008-10-29 US US12/289,492 patent/US7619088B2/en active Active
- 2008-11-25 EP EP08169873A patent/EP2062897B9/en active Active
- 2008-11-25 CA CA2644881A patent/CA2644881C/en active Active
- 2008-11-25 PL PL08169873T patent/PL2062897T3/pl unknown
- 2008-11-25 ES ES08169873T patent/ES2391223T3/es active Active
- 2008-11-25 DK DK08169873.0T patent/DK2062897T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2644881A1 (en) | 2009-05-26 |
| EP2062896A1 (en) | 2009-05-27 |
| US7619088B2 (en) | 2009-11-17 |
| ES2391223T3 (es) | 2012-11-22 |
| EP2062897A1 (en) | 2009-05-27 |
| CA2640316A1 (en) | 2009-05-26 |
| US20090137809A1 (en) | 2009-05-28 |
| CA2644881C (en) | 2013-02-19 |
| PL2062897T3 (pl) | 2013-01-31 |
| EP2062897B1 (en) | 2012-09-19 |
| EP2062897B9 (en) | 2012-12-05 |
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