|
US4057685A
(en)
|
1972-02-02 |
1977-11-08 |
Abbott Laboratories |
Chemically modified endotoxin immunizing agent
|
|
DE2848965A1
(de)
|
1978-11-11 |
1980-05-22 |
Behringwerke Ag |
Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine
|
|
US4673574A
(en)
|
1981-08-31 |
1987-06-16 |
Anderson Porter W |
Immunogenic conjugates
|
|
US4459286A
(en)
|
1983-01-31 |
1984-07-10 |
Merck & Co., Inc. |
Coupled H. influenzae type B vaccine
|
|
US4663160A
(en)
|
1983-03-14 |
1987-05-05 |
Miles Laboratories, Inc. |
Vaccines for gram-negative bacteria
|
|
US4761283A
(en)
|
1983-07-05 |
1988-08-02 |
The University Of Rochester |
Immunogenic conjugates
|
|
US4808700A
(en)
|
1984-07-09 |
1989-02-28 |
Praxis Biologics, Inc. |
Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
|
|
IT1187753B
(it)
|
1985-07-05 |
1987-12-23 |
Sclavo Spa |
Coniugati glicoproteici ad attivita' immunogenica trivalente
|
|
US4803070A
(en)
*
|
1986-04-15 |
1989-02-07 |
Ribi Immunochem Research Inc. |
Immunological emulsion adjuvants for polysaccharide vaccines
|
|
US5204098A
(en)
|
1988-02-16 |
1993-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polysaccharide-protein conjugates
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
NL8802046A
(nl)
|
1988-08-18 |
1990-03-16 |
Gen Electric |
Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
|
|
DE3841091A1
(de)
|
1988-12-07 |
1990-06-13 |
Behringwerke Ag |
Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
|
|
DE68907045T2
(de)
|
1989-01-17 |
1993-12-02 |
Eniricerche Spa |
Synthetische Peptide und deren Verwendung als allgemeine Träger für die Herstellung von immunogenischen Konjugaten, die für die Entwicklung von synthetischen Impfstoffen geeignet sind.
|
|
WO1990014837A1
(en)
|
1989-05-25 |
1990-12-13 |
Chiron Corporation |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
JPH04506662A
(ja)
|
1989-07-14 |
1992-11-19 |
アメリカン・サイアナミド・カンパニー |
接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー
|
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
|
SE466259B
(sv)
|
1990-05-31 |
1992-01-20 |
Arne Forsgren |
Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
|
|
DE69113564T2
(de)
|
1990-08-13 |
1996-05-30 |
American Cyanamid Co |
Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
|
|
IL101007A
(en)
|
1992-02-18 |
1997-08-14 |
Pharmos Ltd |
Dry stable compositions prepared by lyophilization
|
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
|
US5425946A
(en)
|
1992-08-31 |
1995-06-20 |
North American Vaccine, Inc. |
Vaccines against group C Neisseria meningitidis
|
|
JP4097691B2
(ja)
|
1992-08-31 |
2008-06-11 |
バクスター、ヘルスケア、ソシエテ、アノニム |
C群髄膜炎菌に対するワクチン
|
|
AU5543294A
(en)
|
1993-10-29 |
1995-05-22 |
Pharmos Corp. |
Submicron emulsions as vaccine adjuvants
|
|
GB9422096D0
(en)
*
|
1994-11-02 |
1994-12-21 |
Biocine Spa |
Combined meningitis vaccine
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
US6180111B1
(en)
|
1995-05-18 |
2001-01-30 |
University Of Maryland |
Vaccine delivery system
|
|
US6080725A
(en)
|
1997-05-20 |
2000-06-27 |
Galenica Pharmaceuticals, Inc. |
Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
|
|
WO1998053851A1
(en)
|
1997-05-28 |
1998-12-03 |
University Of Iowa Research Foundation |
Laft mutants of pathogenic gram-negative bacteria
|
|
GB9711964D0
(en)
|
1997-06-09 |
1997-08-06 |
Medical Res Council |
Live attenuated vaccines
|
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
|
EP0991761B1
(en)
|
1997-08-21 |
2008-01-16 |
De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur |
Novel mutants of gram negative mucosal bacteria and application thereof in vaccines
|
|
EP1900818A3
(en)
|
1997-11-06 |
2008-06-11 |
Novartis Vaccines and Diagnostics S.r.l. |
Neisserial antigens
|
|
WO1999036544A2
(en)
|
1998-01-14 |
1999-07-22 |
Chiron S.P.A. |
Neisseria meningitidis antigens
|
|
ATE513042T1
(de)
*
|
1998-02-05 |
2011-07-15 |
Glaxosmithkline Biolog Sa |
Tumorassoziierte antigenderivate der mage-familie,nukleinsäuresequenzen, die dafür kodieren, zur herstellung von fusionsproteinen und zusammensetzungen zur impfung
|
|
US7018637B2
(en)
|
1998-02-23 |
2006-03-28 |
Aventis Pasteur, Inc |
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
|
|
US6645503B1
(en)
|
1998-03-10 |
2003-11-11 |
Wyeth Holdings Corporation |
Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria
|
|
EP2261347A3
(en)
|
1998-05-01 |
2012-01-11 |
Novartis Vaccines and Diagnostics, Inc. |
Neisseria meningitidis antigens and compositions
|
|
EP1741443B1
(en)
*
|
1998-05-29 |
2014-05-21 |
Novartis Vaccines and Diagnostics, Inc. |
Combination meningitidis B/C vaccines
|
|
JP5074644B2
(ja)
*
|
1998-05-29 |
2012-11-14 |
ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド |
組合わせの髄膜炎菌b/cワクチン
|
|
CN1263510C
(zh)
|
1998-08-19 |
2006-07-12 |
巴克斯特健康护理股份有限公司 |
多糖-蛋白质缀合物或寡糖-蛋白质缀合物、其制备方法及其应用
|
|
MXPA01003557A
(es)
|
1998-10-09 |
2004-04-05 |
Chiron Corp |
Secuencias genomicas de neisseria y metodos para su uso.
|
|
GB9823978D0
(en)
|
1998-11-02 |
1998-12-30 |
Microbiological Res Authority |
Multicomponent meningococcal vaccine
|
|
PT1127137E
(pt)
|
1998-11-03 |
2007-12-28 |
Staat Nl Verteg Door Min Welzi |
Lps com toxicidade reduzida a partir de bactérias gramnegativas modificadas geneticamente
|
|
AU1626199A
(en)
|
1998-12-04 |
2000-06-26 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
A vi-repa conjugate vaccine for immunization against salmonella typhi
|
|
JP2002539273A
(ja)
|
1999-03-19 |
2002-11-19 |
スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム |
ワクチン
|
|
CA2365914A1
(en)
|
1999-04-09 |
2000-10-19 |
Techlab, Inc. |
Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
|
|
GB9918319D0
(en)
|
1999-08-03 |
1999-10-06 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
US6531131B1
(en)
|
1999-08-10 |
2003-03-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Conjugate vaccine for Neisseria meningitidis
|
|
GB9925559D0
(en)
|
1999-10-28 |
1999-12-29 |
Smithkline Beecham Biolog |
Novel method
|
|
AU1917501A
(en)
|
1999-11-12 |
2001-06-06 |
University Of Iowa Research Foundation, The |
Control of neisserial membrane synthesis
|
|
CA2871789C
(en)
|
2000-01-17 |
2017-04-04 |
Novartis Vaccines And Diagnostics S.R.L. |
Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
|
|
DK1947187T5
(da)
|
2000-02-28 |
2011-10-24 |
Novartis Vaccines & Diagnostic |
Hybrid ekspression af neisserial-proteiner
|
|
GB0007432D0
(en)
|
2000-03-27 |
2000-05-17 |
Microbiological Res Authority |
Proteins for use as carriers in conjugate vaccines
|
|
NO20002828D0
(no)
|
2000-06-02 |
2000-06-02 |
Statens Inst For Folkehelse |
Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav
|
|
KR20030024811A
(ko)
|
2000-07-27 |
2003-03-26 |
칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 |
나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신
|
|
GB0103170D0
(en)
|
2001-02-08 |
2001-03-28 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
PT2332581E
(pt)
|
2001-01-23 |
2015-10-16 |
Sanofi Pasteur Inc |
Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197
|
|
GB0103171D0
(en)
|
2001-02-08 |
2001-03-28 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
US20030035806A1
(en)
|
2001-05-11 |
2003-02-20 |
D'ambra Anello J. |
Novel meningitis conjugate vaccine
|
|
GB0115176D0
(en)
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
|
DK1777236T3
(da)
|
2002-03-26 |
2017-02-27 |
Glaxosmithkline Biologicals Sa |
Modificerede sakkarider, som har forbedret stabilitet i vand til anvendelse som et medikament
|
|
GB0302218D0
(en)
*
|
2003-01-30 |
2003-03-05 |
Chiron Sri |
Vaccine formulation & Mucosal delivery
|
|
GB0213622D0
(en)
|
2002-06-13 |
2002-07-24 |
Glaxosmithkline Biolog Sa |
Vaccine Corporation
|
|
CA2493124C
(en)
|
2002-08-02 |
2014-04-29 |
Glaxosmithkline Biologicals S.A. |
Vaccine
|
|
GB0218821D0
(en)
*
|
2002-08-13 |
2002-09-18 |
Glaxosmithkline Biolog Sa |
Novel compositions
|
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
|
JP2006502228A
(ja)
*
|
2002-10-07 |
2006-01-19 |
カイロン コーポレイション |
Hivワクチン処方物
|
|
CN1809380B
(zh)
|
2002-10-11 |
2010-05-12 |
启龙有限公司 |
广泛防御高毒性脑膜炎球菌谱系的多肽-疫苗
|
|
WO2004046177A2
(en)
*
|
2002-11-15 |
2004-06-03 |
Chiron Srl |
Unexpected surface proteins in neisseria meningitidis
|
|
GB0227346D0
(en)
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
|
ES2461350T3
(es)
*
|
2003-01-30 |
2014-05-19 |
Novartis Ag |
Vacunas inyectables contra múltiples serogrupos de meningococos
|
|
EP1608403A2
(en)
*
|
2003-04-02 |
2005-12-28 |
Coley Pharmaceutical Group, Ltd. |
Immunostimulatory nucleic acid oil-in-water formulations for topical application
|
|
GB0316560D0
(en)
|
2003-07-15 |
2003-08-20 |
Chiron Srl |
Vesicle filtration
|
|
NZ546430A
(en)
*
|
2003-10-02 |
2009-04-30 |
Novartis Vaccines & Diagnostic |
Liquid vaccines for multiple meningococcal serogroups
|
|
GB0323103D0
(en)
|
2003-10-02 |
2003-11-05 |
Chiron Srl |
De-acetylated saccharides
|
|
JP5173194B2
(ja)
*
|
2003-12-23 |
2013-03-27 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
ワクチン
|
|
JP5393978B2
(ja)
|
2004-04-05 |
2014-01-22 |
ゾエティス・ピー・エルエルシー |
マイクロ流動化された水中油型乳剤及びワクチン組成物
|
|
GB0409745D0
(en)
*
|
2004-04-30 |
2004-06-09 |
Chiron Srl |
Compositions including unconjugated carrier proteins
|
|
GB0419627D0
(en)
|
2004-09-03 |
2004-10-06 |
Chiron Srl |
Immunogenic bacterial vesicles with outer membrane proteins
|
|
WO2007013893A2
(en)
*
|
2004-11-15 |
2007-02-01 |
Novartis Vaccines And Diagnostics Inc. |
Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant
|
|
LT2682126T
(lt)
|
2005-01-27 |
2017-02-27 |
Children`s Hospital & Research Center at Oakland |
Gna1870 pagrindu gaminamos pūslelių pavidalo vakcinos, skirtos plataus spektro apsaugai nuo neisseria meningitidis sukeltų ligų
|
|
PE20061428A1
(es)
|
2005-03-23 |
2007-01-16 |
Glaxosmithkline Biolog Sa |
Formulacion de vacuna que comprende un adyuvante de emulsion aceite en agua y 3d-mpl
|
|
US20060228369A1
(en)
|
2005-04-11 |
2006-10-12 |
Program For Appropriate Technology In Health |
Stabilization and preservation of temperature-sensitive vaccines
|
|
US7691368B2
(en)
|
2005-04-15 |
2010-04-06 |
Merial Limited |
Vaccine formulations
|
|
US8156755B2
(en)
*
|
2005-06-03 |
2012-04-17 |
Intervet International B.V. |
Refrigerator for storing vials and cartridge for use in the same
|
|
LT2351578T
(lt)
|
2005-06-27 |
2017-04-10 |
Glaxosmithkline Biologicals S.A. |
Vakcinų gavimo būdas
|
|
US8703095B2
(en)
|
2005-07-07 |
2014-04-22 |
Sanofi Pasteur S.A. |
Immuno-adjuvant emulsion
|
|
BRPI0620460B8
(pt)
|
2005-12-22 |
2021-05-25 |
Glaxosmithkline Biologicals Sa |
uso de composição imunogênica para bebês, e, processo para produzir uma vacina
|
|
AU2007221154A1
(en)
*
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
|
GB0700135D0
(en)
*
|
2007-01-04 |
2007-02-14 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
JP5637848B2
(ja)
*
|
2007-06-04 |
2014-12-10 |
ノバルティス アーゲー |
髄膜炎ワクチンの製剤化
|