DK2261249T3 - KDR-peptider og vacciner omfattende det samme - Google Patents
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- DK2261249T3 DK2261249T3 DK10010173.2T DK10010173T DK2261249T3 DK 2261249 T3 DK2261249 T3 DK 2261249T3 DK 10010173 T DK10010173 T DK 10010173T DK 2261249 T3 DK2261249 T3 DK 2261249T3
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Claims (15)
1. Nonapeptid bestående af aminosyresekvensen ifølge SEQ ID NO: 2.
2. Peptid med cytotoksisk T-celleinducerbarhed, hvor en eller to aminosyrer er substitueret eller tilsat til aminosyresekvensen ifølge SEQ ID NO: 2, hvor den anden aminosyre fra N-terminus er phenylalanin, tyrosin, methionin, eller thryptophan.
3. Peptid med cytotoksisk T-celleinducerbarhed, hvor en eller to aminosyrer er substitueret eller tilsat til aminosyresekvensen ifølge SEQ ID NO: 2, hvor den C-terminale aminosyre er phenylalanin, leucin, isoleucin, thryptophan, eller methionin.
4. Peptidet ifølge krav 2, hvor den C-terminale aminosyre er phenylalanin, leucin, isoleucin, tryptophan, eller methionin.
5. Farmaceutisk sammensætning omfattende ét eller flere peptider ifølge et hvilket som helst af kravene 1 til 4.
6. Vaccine omfattende et peptid ifølge et hvilket som helst af kravene 1 til 4 som en aktiv bestanddel.
7. Peptid til anvendelse i behandling og forebyggelse af tumorer, hvor peptidet er valgt fra gruppen bestående af peptiderne ifølge kravene 2 til 4.
8. Peptid til anvendelse i behandling af diabetisk retinopati, kronisk rheumatoid arthritis, psoriasis, og aterosklerose, hvor peptidet er valgt fra gruppen bestående af peptiderne ifølge kravene 1 til 4.
9. Farmaceutisk sammensætning til anvendelse i behandling og forebyggelse af tumorer, hvor den farmaceutiske sammensætning omfatter ét eller flere peptider ifølge et hvilket som helst af kravene 2 til 4.
10. Farmaceutisk sammensætning til anvendelse i behandling af diabetisk retinopati, kronisk rheumatoid arthritis, psoriasis, og aterosklerose, hvor den farmaceutiske sammensætning omfatter ét eller flere peptider ifølge et hvilket som helst af kravene 1 til 4
11. Exosom der udviser et kompleks på dets overflade bestående af et peptid ifølge et hvilket som helst af kravene 1 til 4, og et HLA-A2402-antigen.
12. Vaccine til anvendelse i behandling og forebyggelse af tumorer, hvor vaccinen omfatter et peptid ifølge et hvilket som helst af kravene 2 til 4 som en aktiv bestanddel.
13. Vaccine til anvendelse i behandling af diabetisk retinopati, kronisk rheumatoid arthritis, psoriasis, og aterosklerose, hvor vaccinen omfatter et peptid ifølge et hvilket som helst af kravene 1 til 4 som en aktiv bestanddel.
14. Peptidet ifølge krav 7 eller 8, den farmaceutiske sammensætning ifølge krav 9 eller 10, eller vaccinen ifølge krav 12 eller 13, der anvendes til administration til et individ hvis HLA-antigen er HLA-A24.
15. Peptidet, den farmaceutiske sammensætning, eller vaccinen ifølge krav 14, der anvendes til administration til et individ hvis HLA-antigen er HLA-A2402.
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- 2003-09-12 EP EP10010173.2A patent/EP2261249B1/en not_active Expired - Lifetime
- 2003-09-12 CN CNB038250810A patent/CN100352843C/zh not_active Expired - Lifetime
- 2003-09-12 EP EP10010174.0A patent/EP2267022B1/en not_active Expired - Lifetime
-
2007
- 2007-03-08 JP JP2007058127A patent/JP4185143B2/ja not_active Expired - Fee Related
- 2007-05-08 JP JP2007123850A patent/JP4185147B2/ja not_active Expired - Fee Related
-
2009
- 2009-01-16 US US12/355,616 patent/US7695720B2/en not_active Expired - Lifetime
- 2009-08-12 CY CY20091100856T patent/CY1109463T1/el unknown
-
2010
- 2010-02-23 US US12/711,159 patent/US8206719B2/en not_active Expired - Fee Related
-
2012
- 2012-01-19 CY CY20121100072T patent/CY1113379T1/el unknown
- 2012-06-12 US US13/494,933 patent/US8574586B2/en not_active Expired - Fee Related
- 2012-06-12 US US13/494,930 patent/US8574585B2/en not_active Expired - Fee Related
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