DK2263677T3 - Nye terapeutiske anvendelser af inecalcitol - Google Patents

Nye terapeutiske anvendelser af inecalcitol

Info

Publication number: DK2263677T3
Authority: DK; Denmark
Prior art keywords: inecalcitol; therapeutic applications; new therapeutic; day; type
Prior art date: 2009-05-20

Application number

DK10163156.2T

Other languages

English (en)

Inventor

Remi Delansorne

Jean-Francois Dufour-Lamartinie

Original Assignee

Hybrigenics Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-05-20

Filing date

2010-05-18

Publication date

2011-06-06

2010-05-18 Application filed by Hybrigenics Sa filed Critical Hybrigenics Sa

2011-06-06 Application granted granted Critical

2011-06-06 Publication of DK2263677T3 publication Critical patent/DK2263677T3/da

Links

BUDPDEVHCQIFNU-PUBYVPDWSA-N inecalcitol Chemical compound C1(/[C@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CC#CC(C)(C)O)C)=C/C=C1/C[C@@H](O)C[C@H](O)C1=C BUDPDEVHCQIFNU-PUBYVPDWSA-N 0.000 title abstract 2
229950003028 inecalcitol Drugs 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
208000023275 Autoimmune disease Diseases 0.000 abstract 1
206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
201000002980 Hyperparathyroidism Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
201000004681 Psoriasis Diseases 0.000 abstract 1
206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
229930003316 Vitamin D Natural products 0.000 abstract 1
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
201000006417 multiple sclerosis Diseases 0.000 abstract 1
208000005368 osteomalacia Diseases 0.000 abstract 1
208000007442 rickets Diseases 0.000 abstract 1
235000019166 vitamin D Nutrition 0.000 abstract 1
239000011710 vitamin D Substances 0.000 abstract 1
150000003710 vitamin D derivatives Chemical class 0.000 abstract 1
229940046008 vitamin d Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Immunology (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Epidemiology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Nutrition Science (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Oncology (AREA)
Reproductive Health (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Physiology (AREA)
Transplantation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK10163156.2T 2009-05-20 2010-05-18 Nye terapeutiske anvendelser af inecalcitol DK2263677T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17990609P	2009-05-20	2009-05-20

Publications (1)

Publication Number	Publication Date
DK2263677T3 true DK2263677T3 (da)	2011-06-06

Family

ID=42308305

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10163156.2T DK2263677T3 (da)	2009-05-20	2010-05-18	Nye terapeutiske anvendelser af inecalcitol

Country Status (23)

Country	Link
US (1)	US8481514B2 (da)
EP (1)	EP2263677B1 (da)
JP (2)	JP2012527424A (da)
KR (1)	KR101845320B1 (da)
CN (1)	CN102448466A (da)
AT (1)	ATE505194T1 (da)
AU (1)	AU2010261967B2 (da)
BR (1)	BRPI1009056A2 (da)
CA (1)	CA2762458C (da)
DE (1)	DE602010000019D1 (da)
DK (1)	DK2263677T3 (da)
ES (1)	ES2363070T3 (da)
HR (1)	HRP20110433T1 (da)
IL (1)	IL216418A (da)
MX (1)	MX2011012330A (da)
NZ (1)	NZ596497A (da)
PL (1)	PL2263677T3 (da)
PT (1)	PT2263677E (da)
RU (1)	RU2571490C2 (da)
SG (1)	SG176581A1 (da)
SI (1)	SI2263677T1 (da)
UA (1)	UA105792C2 (da)
WO (1)	WO2010145903A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK2360145T3 (da)	2010-01-26	2012-07-09	Hybrigenics Sa	Hidtil ukendt fremgangsmåde til isomerisering af kondenserede bicykliske strukturer og fremstilling af D-vitaminanaloger, der omfatter disse
EP2407152A1 (en) *	2010-07-15	2012-01-18	Hybrigenics S.A.	Formulations of 14-epi-analogues of vitamin D
AU2011278346B2 (en) *	2010-07-15	2016-04-07	Hybrigenics Sa	New formulations of 14 - epi -analogues of vitamin D
US20120015913A1 (en)	2010-07-15	2012-01-19	Delansorne Remi	Formulations of 14-EPI-Analogues of Vitamin D
WO2015193480A1 (en) *	2014-06-19	2015-12-23	INSERM (Institut National de la Santé et de la Recherche Médicale)	Composition comprising a combination of dna methylation inhibitor and a vitamin d receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse
SG11201809501PA (en)	2016-06-06	2018-12-28	Celgene Corp	Treatment of a hematologic malignancy with 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide
JP2020143008A (ja) *	2019-03-05	2020-09-10	達也楠堂	新規褐色脂肪細胞分化誘導剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU699200B2 (en)	1993-07-09	1998-11-26	Roger Bouillon	Novel structural analogues of vitamin D
US6242434B1 (en) *	1997-08-08	2001-06-05	Bone Care International, Inc.	24-hydroxyvitamin D, analogs and uses thereof
GB0305332D0 (en) *	2003-03-10	2003-04-09	Leuven K U Res & Dev	Biological evaluation of novel vitamin D analogues
CA2580962A1 (en) *	2004-09-24	2006-04-06	Bioxell S.P.A.	20-cycloalkyl,26,27-alkyl/haloalkyl vitamin d3 compounds and methods of use thereof

2010
- 2010-05-18 NZ NZ596497A patent/NZ596497A/xx not_active IP Right Cessation
- 2010-05-18 EP EP10163156A patent/EP2263677B1/en active Active
- 2010-05-18 KR KR1020117030464A patent/KR101845320B1/ko not_active Expired - Fee Related
- 2010-05-18 AT AT10163156T patent/ATE505194T1/de active
- 2010-05-18 SI SI201030002T patent/SI2263677T1/sl unknown
- 2010-05-18 BR BRPI1009056-8A patent/BRPI1009056A2/pt not_active Application Discontinuation
- 2010-05-18 JP JP2012511265A patent/JP2012527424A/ja active Pending
- 2010-05-18 RU RU2011151854/15A patent/RU2571490C2/ru not_active IP Right Cessation
- 2010-05-18 SG SG2011085776A patent/SG176581A1/en unknown
- 2010-05-18 WO PCT/EP2010/056832 patent/WO2010145903A1/en not_active Ceased
- 2010-05-18 MX MX2011012330A patent/MX2011012330A/es active IP Right Grant
- 2010-05-18 CA CA2762458A patent/CA2762458C/en not_active Expired - Fee Related
- 2010-05-18 PT PT10163156T patent/PT2263677E/pt unknown
- 2010-05-18 UA UAA201113630A patent/UA105792C2/uk unknown
- 2010-05-18 AU AU2010261967A patent/AU2010261967B2/en not_active Ceased
- 2010-05-18 PL PL10163156T patent/PL2263677T3/pl unknown
- 2010-05-18 CN CN2010800222064A patent/CN102448466A/zh active Pending
- 2010-05-18 US US12/782,301 patent/US8481514B2/en not_active Expired - Fee Related
- 2010-05-18 ES ES10163156T patent/ES2363070T3/es active Active
- 2010-05-18 DE DE602010000019T patent/DE602010000019D1/de active Active
- 2010-05-18 DK DK10163156.2T patent/DK2263677T3/da active
2011
- 2011-06-09 HR HR20110433T patent/HRP20110433T1/hr unknown
- 2011-11-17 IL IL216418A patent/IL216418A/en not_active IP Right Cessation
2016
- 2016-06-09 JP JP2016115489A patent/JP2016179994A/ja active Pending

Also Published As

Publication number	Publication date
IL216418A0 (en)	2012-02-29
SI2263677T1 (sl)	2011-07-29
UA105792C2 (uk)	2014-06-25
EP2263677B1 (en)	2011-04-13
RU2011151854A (ru)	2013-06-27
RU2571490C2 (ru)	2015-12-20
JP2016179994A (ja)	2016-10-13
KR20120017075A (ko)	2012-02-27
EP2263677A1 (en)	2010-12-22
SG176581A1 (en)	2012-01-30
PL2263677T3 (pl)	2011-09-30
CN102448466A (zh)	2012-05-09
US20110015276A1 (en)	2011-01-20
DE602010000019D1 (de)	2011-05-26
JP2012527424A (ja)	2012-11-08
AU2010261967B2 (en)	2016-03-03
ES2363070T3 (es)	2011-07-19
WO2010145903A1 (en)	2010-12-23
MX2011012330A (es)	2011-12-16
ATE505194T1 (de)	2011-04-15
AU2010261967A1 (en)	2011-12-08
CA2762458A1 (en)	2010-12-23
HRP20110433T1 (hr)	2011-07-31
US8481514B2 (en)	2013-07-09
NZ596497A (en)	2013-05-31
KR101845320B1 (ko)	2018-04-04
PT2263677E (pt)	2011-06-01
BRPI1009056A2 (pt)	2020-06-02
CA2762458C (en)	2018-08-28
IL216418A (en)	2015-09-24

Publication	Publication Date	Title
MX2024000208A (es)	2024-01-29	Restos de administracion terapeutica novedosos y usos de estos.
IL216418A0 (en)	2012-02-29	New therapeutical uses of inecalcitol
NO20071428L (no)	2007-04-02	Kombinasjon inneholdende ZD6474 og Imatinib
MX361467B (es)	2018-12-06	Compuestos de isoindolina para uso en el tratamiento de cancer.
DOP2007000053A (es)	2007-09-30	Compuestos de tetrahidropiridotienopirimidina y métodos para su empleo
NO20071426L (no)	2007-06-18	Kreft kombinasjonsbehandling omfattende AZD2171 og Imatinib
MX2013013809A (es)	2013-12-16	Dispositivos expandibles con revestimiento de una composicion de paclitaxel.
ECSP10010289A (es)	2010-07-30	Régimen de dosificación asociado con ésteres de paliperidona inyectables de acción prolongada
MX2015017961A (es)	2016-10-14	Compuestos orgánicos pirrolo-pirrol carbamato y relacionados, composiciones farmacéuticas y usos médicos de los mismos.
CR7785A (es)	2005-07-08	Compuestos de tiazol para el tratamiento de trastornos neurodegenerativos
EP4364801A3 (en)	2024-07-10	Optimised dosage of diaminophenothiazines in populations
EA200870254A1 (ru)	2008-12-30	Способ лечения воспалительных заболеваний
CY1111547T1 (el)	2015-08-05	Συνδυασμος zd6474 και πεμετρεξεδης
UY31346A1 (es)	2009-04-30	Compuestos que tienen actividad en el receptor m1 y sus usos en medicina
WO2013040227A3 (en)	2013-07-25	Therapeutic compounds
NO20072167L (no)	2007-05-22	Kombinasjon omfattende ZD6474 og et antiandrogen
EA201001085A1 (ru)	2011-02-28	Фармацевтические композиции, содержащие гранулы очищенной микробной липазы, и способы предупреждения или лечения пищеварительных нарушений
CY1114760T1 (el)	2016-12-14	Θεραπευτικη αγωγη αθηροσκληρωσης
CL2009000949A1 (es)	2010-12-24	Compuestos derivados de 1,2,3,5-tetrahidro-indolizina, 6,7,8,9-tetrahidro-4h-quinolizina sustituidos, inhibidores de la actividad de cinasa de mek; su composicion farmaceutica; su uso para el tratamiento de enfermedades hiperproliferativas, tal como cancer e inflamaciones.
UY29161A1 (es)	2006-04-28	Nuevos heterociclos
JP2012527424A5 (da)	2013-07-04
NO20076657L (no)	2008-04-03	Kombinasjonsterapi av cancer med AZD2171 og gemcitabin
NZ606678A (en)	2014-11-28	Formulations of 14-epi-analogues of vitamin d
ATE502641T1 (de)	2011-04-15	Kombination aus azd2171 und pemetrexed
NO20056170L (no)	2006-02-08	Kreftkombinasjonsterapi omfattende AZD2171 of ZD1839