DK2308982T3 - Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider - Google Patents

Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider Download PDF

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Publication number
DK2308982T3
DK2308982T3 DK10179786T DK10179786T DK2308982T3 DK 2308982 T3 DK2308982 T3 DK 2308982T3 DK 10179786 T DK10179786 T DK 10179786T DK 10179786 T DK10179786 T DK 10179786T DK 2308982 T3 DK2308982 T3 DK 2308982T3
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Prior art keywords
peptides
members
methods
genetic packages
diverse family
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DK10179786T
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English (en)
Inventor
Robert C Ladner
Edward Hirsch Cohen
Horacio Gabriel Nastri
Kristin L Rookey
Rene Hoet
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Dyax Corp
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Publication of DK2308982T3 publication Critical patent/DK2308982T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
DK10179786T 2000-04-17 2001-04-17 Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider DK2308982T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19806900P 2000-04-17 2000-04-17
EP01927108A EP1276855B1 (en) 2000-04-17 2001-04-17 Methods of constructing display libraries of genetic packages for members of a diverse family of peptides

Publications (1)

Publication Number Publication Date
DK2308982T3 true DK2308982T3 (da) 2015-03-02

Family

ID=22731873

Family Applications (3)

Application Number Title Priority Date Filing Date
DK10179786T DK2308982T3 (da) 2000-04-17 2001-04-17 Fremgangsmåder til konstruering af præsentationsbiblioteker af genetiske pakker til medlemmer af en uensartet familie af peptider
DK01927108.9T DK1276855T3 (da) 2000-04-17 2001-04-17 Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie
DK10156326.0T DK2199393T3 (da) 2000-04-17 2001-04-17 Hidtil ukendte fremgangsmåder til opbygning af biblioteker over genetiske pakker, der kollektivt viser medlemmerne af en forskelligartet familie af peptider, polypeptider eller proteiner

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK01927108.9T DK1276855T3 (da) 2000-04-17 2001-04-17 Fremgangsmåde til konstruktion af visningsbiblioteker over genetiske pakker for medlemmer af en diversificeret peptidfamilie
DK10156326.0T DK2199393T3 (da) 2000-04-17 2001-04-17 Hidtil ukendte fremgangsmåder til opbygning af biblioteker over genetiske pakker, der kollektivt viser medlemmerne af en forskelligartet familie af peptider, polypeptider eller proteiner

Country Status (9)

Country Link
US (2) US20040029113A1 (da)
EP (4) EP2199393B1 (da)
JP (3) JP5149476B2 (da)
AU (3) AU2001253589B2 (da)
CA (2) CA2406236C (da)
DK (3) DK2308982T3 (da)
ES (3) ES2531551T3 (da)
PT (1) PT2308982E (da)
WO (1) WO2001079481A2 (da)

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US8691730B2 (en) 2007-09-14 2014-04-08 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
FR2924440B1 (fr) * 2007-12-04 2015-01-09 Pf Medicament Nouveau procede de generation et de criblage d'une banque d'anticorps
US9873957B2 (en) 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
ES2528963T3 (es) 2008-04-24 2015-02-13 Dyax Corp. Bibliotecas de paquetes genéticos que comprenden nuevos diseños de CDR1, CDR2, y CDR3 de HC y nuevos diseños de CDR1, CDR2, y CDR3 de LC
CN102165073A (zh) * 2008-07-10 2011-08-24 骆树恩 用于核酸作图和鉴定核酸中的精细结构变化的方法
US20110082054A1 (en) * 2009-09-14 2011-04-07 Dyax Corp. Libraries of genetic packages comprising novel hc cdr3 designs
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Also Published As

Publication number Publication date
EP1276855A2 (en) 2003-01-22
EP2199393B1 (en) 2012-10-31
JP2003530853A (ja) 2003-10-21
HK1145515A1 (en) 2011-04-21
JP2014064586A (ja) 2014-04-17
PT2308982E (pt) 2015-03-04
HK1156656A1 (en) 2012-06-15
ES2400302T8 (es) 2013-04-25
CA2406236C (en) 2013-02-19
WO2001079481A8 (en) 2002-12-19
DK1276855T3 (da) 2012-11-26
CA2798625A1 (en) 2001-10-25
ES2393535T3 (es) 2012-12-26
JP2011135893A (ja) 2011-07-14
EP2295580A1 (en) 2011-03-16
CA2406236A1 (en) 2001-10-25
AU5358901A (en) 2001-10-30
AU2001253589B2 (en) 2007-08-16
JP5599745B2 (ja) 2014-10-01
WO2001079481A2 (en) 2001-10-25
US9382535B2 (en) 2016-07-05
EP1276855B1 (en) 2012-10-24
JP5149476B2 (ja) 2013-02-20
ES2531551T3 (es) 2015-03-17
EP2308982A1 (en) 2011-04-13
US20060166252A1 (en) 2006-07-27
DK2199393T3 (da) 2012-11-26
AU2007211861A1 (en) 2007-09-06
JP5956413B2 (ja) 2016-07-27
US20040029113A1 (en) 2004-02-12
EP2308982B1 (en) 2014-11-26
WO2001079481A3 (en) 2002-07-04
CA2798625C (en) 2017-01-24
AU2007211861B2 (en) 2009-06-11
ES2400302T3 (es) 2013-04-09
EP2199393A1 (en) 2010-06-23

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