DK2343275T3 - Krystallinsk form af optiske enantiomerer af modafinil - Google Patents

Krystallinsk form af optiske enantiomerer af modafinil

Info

Publication number: DK2343275T3
Authority: DK; Denmark
Prior art keywords: modafinil; crystalline form; optical enantiomers; enantiomers; optical
Prior art date: 2002-12-20

Application number

DK11163602.3T

Other languages

English (en)

Inventor

Gilles Serrure

Franck Mallet

Sebastien Rose

Olivier Neckebrock

Laurent Courvoisier

Stephanie Graf

Gerard Coquerel

Christine Besselievre

Langevelde Adriaan Jan Van

Pierre Leproust

Original Assignee

Teva Sante

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-20

Filing date

2003-12-18

Publication date

2013-07-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32406320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2343275(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-12-18 Application filed by Teva Sante filed Critical Teva Sante

2013-07-01 Application granted granted Critical

2013-07-01 Publication of DK2343275T3 publication Critical patent/DK2343275T3/da

Links

YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 title 1
229960001165 modafinil Drugs 0.000 title 1
230000003287 optical effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/06—Separation; Purification; Stabilisation; Use of additives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Nutrition Science (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK11163602.3T 2002-12-20 2003-12-18 Krystallinsk form af optiske enantiomerer af modafinil DK2343275T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0216412A FR2849029B1 (fr)	2002-12-20	2002-12-20	Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
EP03799631.1A EP1572635B1 (fr)	2002-12-20	2003-12-18	Procede de preparation et formes cristallines des enantiomeres optiques du modafinil

Publications (1)

Publication Number	Publication Date
DK2343275T3 true DK2343275T3 (da)	2013-07-01

Family

ID=32406320

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK11163602.3T DK2343275T3 (da)	2002-12-20	2003-12-18	Krystallinsk form af optiske enantiomerer af modafinil

Country Status (30)

Country	Link
US (10)	US7132570B2 (da)
EP (6)	EP2343275B1 (da)
JP (2)	JP4719471B2 (da)
KR (1)	KR101050565B1 (da)
CN (5)	CN101654423A (da)
AR (1)	AR042546A1 (da)
AU (2)	AU2003299349C1 (da)
BR (1)	BRPI0316916B1 (da)
CA (2)	CA2510096C (da)
CL (2)	CL2007002450A1 (da)
CY (1)	CY1114291T1 (da)
DK (1)	DK2343275T3 (da)
EA (1)	EA009592B1 (da)
EG (1)	EG24849A (da)
ES (3)	ES2575018T3 (da)
FR (1)	FR2849029B1 (da)
HK (1)	HK1225371A1 (da)
IL (1)	IL169205A (da)
IS (1)	IS7947A (da)
MX (1)	MXPA05006525A (da)
MY (1)	MY142926A (da)
NO (1)	NO335724B1 (da)
NZ (2)	NZ540733A (da)
PL (1)	PL377196A1 (da)
PT (1)	PT2343275E (da)
SI (1)	SI2343275T1 (da)
TW (1)	TWI344952B (da)
UA (1)	UA100964C2 (da)
WO (1)	WO2004060858A1 (da)
ZA (1)	ZA200504805B (da)

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2002
- 2002-12-20 FR FR0216412A patent/FR2849029B1/fr not_active Expired - Fee Related
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- 2003-12-18 CN CN200910152177A patent/CN101654423A/zh active Pending
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Also Published As

Publication number	Publication date
PT2343275E (pt)	2013-07-30
SI2343275T1 (sl)	2013-10-30
EA200501016A1 (ru)	2005-12-29
US20090281192A1 (en)	2009-11-12
EP2343275A3 (fr)	2011-08-17
FR2849029B1 (fr)	2005-03-18
KR101050565B1 (ko)	2011-07-19
EG24849A (en)	2010-10-27
BRPI0316916B1 (pt)	2021-11-30
IS7947A (is)	2005-07-19
EP1572635B1 (fr)	2017-04-12
CL2016002640A1 (es)	2017-03-24
US20060135621A1 (en)	2006-06-22
EP2676952A3 (fr)	2014-02-12
TWI344952B (en)	2011-07-11
US8975442B2 (en)	2015-03-10
US8729305B2 (en)	2014-05-20
US9382200B2 (en)	2016-07-05
US20130274521A1 (en)	2013-10-17
ES2425023T3 (es)	2013-10-10
NO20052912L (no)	2005-07-19
PL377196A1 (pl)	2006-01-23
AU2003299349C1 (en)	2011-01-20
EP2679577A2 (fr)	2014-01-01
US20100048718A1 (en)	2010-02-25
AU2003299349A8 (en)	2004-07-29
HK1192222A1 (zh)	2014-08-15
EP2343275A2 (fr)	2011-07-13
AU2003299349B2 (en)	2010-06-03
CN101914044A (zh)	2010-12-15
EP2679578A2 (fr)	2014-01-01
NO20052912D0 (no)	2005-06-15
CN1751021A (zh)	2006-03-22
CN100540533C (zh)	2009-09-16
EP2679578A3 (fr)	2014-03-19
EP2679576A3 (fr)	2014-02-12
EA009592B1 (ru)	2008-02-28
US7132570B2 (en)	2006-11-07
JP4719471B2 (ja)	2011-07-06
BR0316916A (pt)	2005-10-18
CA2510096A1 (fr)	2004-07-22
NZ571235A (en)	2010-01-29
EP2343275B1 (fr)	2013-04-24
JP2006511588A (ja)	2006-04-06
CN101012189B (zh)	2013-03-13
FR2849029A1 (fr)	2004-06-25
US20100022653A1 (en)	2010-01-28
US20060241320A1 (en)	2006-10-26
AU2003299349A1 (en)	2004-07-29
AU2010212462A1 (en)	2010-09-16
US20090281193A1 (en)	2009-11-12
EP2679578B1 (fr)	2016-03-09
NO335724B1 (no)	2015-02-02
WO2004060858A1 (fr)	2004-07-22
HK1225371A1 (zh)	2017-09-08
US20100048720A1 (en)	2010-02-25
EP2676952A2 (fr)	2013-12-25
EP2679576A2 (fr)	2014-01-01
ES2627808T3 (es)	2017-07-31
IL169205A (en)	2013-11-28
EP1572635A1 (fr)	2005-09-14
CL2007002450A1 (es)	2009-01-16
UA100964C2 (ru)	2013-02-25
MY142926A (en)	2011-01-31
TW200419175A (en)	2004-10-01
CA2510096C (fr)	2011-02-22
US20140031589A1 (en)	2014-01-30
CN101654423A (zh)	2010-02-24
EP2679577A3 (fr)	2014-02-12
CN106065007A (zh)	2016-11-02
JP2011102330A (ja)	2011-05-26
CA2724305A1 (fr)	2004-07-22
CN101012189A (zh)	2007-08-08
CY1114291T1 (el)	2016-08-31
JP5497680B2 (ja)	2014-05-21
US20100048719A1 (en)	2010-02-25
MXPA05006525A (es)	2005-12-05
KR20050085847A (ko)	2005-08-29
ZA200504805B (en)	2006-07-26
NZ540733A (en)	2008-10-31
ES2575018T3 (es)	2016-06-23
BRPI0316916A8 (pt)	2015-09-22
AR042546A1 (es)	2005-06-22

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