DK2386308T3 - Sted-specifik intestinal frigivelse af adsorbenter, alene eller i kombination med nedbrydende molekyler - Google Patents
Sted-specifik intestinal frigivelse af adsorbenter, alene eller i kombination med nedbrydende molekyler Download PDFInfo
- Publication number
- DK2386308T3 DK2386308T3 DK11176876.8T DK11176876T DK2386308T3 DK 2386308 T3 DK2386308 T3 DK 2386308T3 DK 11176876 T DK11176876 T DK 11176876T DK 2386308 T3 DK2386308 T3 DK 2386308T3
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- Prior art keywords
- cellulose
- pharmaceutical composition
- adsorbent
- adsorbents
- antibiotics
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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Claims (7)
1. Oral administrerbar farmaceutisk sammensætning til sted-specifik intestinal frigivelse af adsorbenter, omfattende: a) en adsorbent valgt fra gruppen bestående af aktivt kul, ler, talkum, silika og resiner, og b) et sted-specifikt leveringssystem til at frigive adsorbenten i ileum eller colon, hvor leveringssystemet er coatet med et coating-materiale eller en kombination af coating-materialer valgt fra: cellulosepolymerer såsom hydroxypropylcellulose, hydroxyethylcellulose, hydroxymethylcellulose, hydroxypropylmethylcellulose, hydroxypropylmethylcellulose-acetatsuccinat, hydroxypropylmethylcellulosephthalat, methylcellulose, ethylcellulose, celluloseacetat, celluloseacetatphthalat, celluloseacetattrimellitat og carboxymethylcellulosenatrium; en tercopolymer af methacrylsyre, methylacrylat og methylmethacrylat; vinylpolymerer og copolymerer såsom polyvinylpyrrolidon, vinylacetat, vinylacetatphthalat, vinylacetatcrotonsyrecopolymer, og ethylen-vinyl acetatcopolymer; azopolymerer eller amylose; og shellak; hvor ud af hundrede vægtprocent af sammensætningen, adsorbenten er i området fra omkring 10 til omkring 99 %.
2. Den farmaceutiske sammensætning ifølge krav 1, hvor adsorbenten er aktivt kul.
3. Den farmaceutiske sammensætning ifølge krav 1 eller 2, hvor coatingmaterialet er en tercopolymer af methacrylsyre, methylacrylat og methylmethacrylat.
4. Den farmaceutiske sammensætning ifølge krav 1, hvor leret er valgt fra gruppen bestående af bentonit, kaolin, montmorillonit, attapulgit, halloysit, og laponit.
5. Den farmaceutiske sammensætning ifølge krav 1, hvor silikaen er valgt fra gruppen bestående af kolloidsilika, mesoporøs silika, pyrogen silika og zeolitter.
6. Den farmaceutiske sammensætning ifølge et hvilket som helst af kravene 1 til 5, yderligere omfattende et enzym, der inaktiverer antibiotika.
7. Den farmaceutiske sammensætning ifølge krav 6, hvor enzymet er en betalactamase eller en erythromycinesterase.
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| US80112106P | 2006-05-17 | 2006-05-17 | |
| EP07765272.5A EP2026823B1 (en) | 2006-05-17 | 2007-05-18 | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
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| DK11176876.8T DK2386308T3 (da) | 2006-05-17 | 2007-05-18 | Sted-specifik intestinal frigivelse af adsorbenter, alene eller i kombination med nedbrydende molekyler |
| DK07765272.5T DK2026823T3 (da) | 2006-05-17 | 2007-05-18 | Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler |
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| Application Number | Title | Priority Date | Filing Date |
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| DK07765272.5T DK2026823T3 (da) | 2006-05-17 | 2007-05-18 | Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler |
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| EP (2) | EP2386308B1 (da) |
| JP (1) | JP5829003B2 (da) |
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| US8048413B2 (en) | 2006-05-17 | 2011-11-01 | Helene Huguet | Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules |
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2007
- 2007-05-17 US US11/804,259 patent/US8048413B2/en not_active Expired - Fee Related
- 2007-05-18 CN CN202011133177.0A patent/CN112891546A/zh active Pending
- 2007-05-18 HU HUE11176876A patent/HUE036492T2/hu unknown
- 2007-05-18 DK DK11176876.8T patent/DK2386308T3/da active
- 2007-05-18 PL PL07765272T patent/PL2026823T3/pl unknown
- 2007-05-18 PL PL11176876T patent/PL2386308T3/pl unknown
- 2007-05-18 JP JP2009510468A patent/JP5829003B2/ja not_active Expired - Fee Related
- 2007-05-18 AU AU2007251565A patent/AU2007251565B2/en not_active Ceased
- 2007-05-18 DK DK07765272.5T patent/DK2026823T3/da active
- 2007-05-18 EP EP11176876.8A patent/EP2386308B1/en active Active
- 2007-05-18 CA CA2651569A patent/CA2651569C/en active Active
- 2007-05-18 PT PT77652725T patent/PT2026823E/pt unknown
- 2007-05-18 WO PCT/EP2007/054831 patent/WO2007132022A2/en not_active Ceased
- 2007-05-18 TR TR2018/02214T patent/TR201802214T4/tr unknown
- 2007-05-18 EP EP07765272.5A patent/EP2026823B1/en active Active
- 2007-05-18 PT PT111768768T patent/PT2386308T/pt unknown
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- 2007-05-18 ES ES07765272.5T patent/ES2472703T3/es active Active
- 2007-05-18 ES ES11176876.8T patent/ES2660234T3/es active Active
- 2007-05-18 BR BRPI0712098A patent/BRPI0712098B8/pt not_active IP Right Cessation
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2011
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2007132022A2 (en) | 2007-11-22 |
| DK2026823T3 (da) | 2014-06-10 |
| HUE036492T2 (hu) | 2018-07-30 |
| BRPI0712098A8 (pt) | 2020-08-18 |
| JP5829003B2 (ja) | 2015-12-09 |
| HK1124793A1 (en) | 2009-07-24 |
| BRPI0712098B1 (pt) | 2020-09-15 |
| CN101969964A (zh) | 2011-02-09 |
| US20080031867A1 (en) | 2008-02-07 |
| PT2026823E (pt) | 2014-06-25 |
| ES2660234T3 (es) | 2018-03-21 |
| JP2009537490A (ja) | 2009-10-29 |
| PL2026823T3 (pl) | 2014-10-31 |
| AU2007251565A1 (en) | 2007-11-22 |
| WO2007132022A3 (en) | 2008-01-10 |
| EP2026823A2 (en) | 2009-02-25 |
| CA2651569A1 (en) | 2007-11-22 |
| EP2386308B1 (en) | 2017-11-29 |
| US8048413B2 (en) | 2011-11-01 |
| TR201802214T4 (tr) | 2018-03-21 |
| EP2386308A1 (en) | 2011-11-16 |
| EP2026823B1 (en) | 2014-05-07 |
| ES2472703T3 (es) | 2014-07-02 |
| BRPI0712098B8 (pt) | 2021-05-25 |
| US8388984B2 (en) | 2013-03-05 |
| PL2386308T3 (pl) | 2018-05-30 |
| BRPI0712098A2 (pt) | 2012-01-17 |
| AU2007251565B2 (en) | 2012-06-28 |
| PT2386308T (pt) | 2018-02-28 |
| US20120107367A1 (en) | 2012-05-03 |
| CN112891546A (zh) | 2021-06-04 |
| CA2651569C (en) | 2016-05-10 |
| WO2007132022A8 (en) | 2008-12-31 |
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