DK2387557T3 - Fremgangsmåde til fremstilling af n-[5-(3-dimethylamino-acryloyl)-2-fluorphenyl]-n-methyl-acetamid - Google Patents

Fremgangsmåde til fremstilling af n-[5-(3-dimethylamino-acryloyl)-2-fluorphenyl]-n-methyl-acetamid

Info

Publication number
DK2387557T3
DK2387557T3 DK10700974.8T DK10700974T DK2387557T3 DK 2387557 T3 DK2387557 T3 DK 2387557T3 DK 10700974 T DK10700974 T DK 10700974T DK 2387557 T3 DK2387557 T3 DK 2387557T3
Authority
DK
Denmark
Prior art keywords
fluorphenyl
acryloyl
acetamide
dimethylamino
methyl
Prior art date
Application number
DK10700974.8T
Other languages
English (en)
Inventor
Rosell Juan Sallares
Francisco Marquillas
Original Assignee
Interquim Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interquim Sa filed Critical Interquim Sa
Application granted granted Critical
Publication of DK2387557T3 publication Critical patent/DK2387557T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK10700974.8T 2009-01-13 2010-01-11 Fremgangsmåde til fremstilling af n-[5-(3-dimethylamino-acryloyl)-2-fluorphenyl]-n-methyl-acetamid DK2387557T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200900089 2009-01-13
PCT/EP2010/050235 WO2010081788A1 (en) 2009-01-13 2010-01-11 Process for the preparation of n-[5-(3-dimethylamino-acryloyl)-2-fluoro-phenyl]-n-methyl-acetamide

Publications (1)

Publication Number Publication Date
DK2387557T3 true DK2387557T3 (da) 2013-09-08

Family

ID=42199324

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10700974.8T DK2387557T3 (da) 2009-01-13 2010-01-11 Fremgangsmåde til fremstilling af n-[5-(3-dimethylamino-acryloyl)-2-fluorphenyl]-n-methyl-acetamid

Country Status (22)

Country Link
US (1) US8163903B2 (da)
EP (1) EP2387557B1 (da)
JP (1) JP5507579B2 (da)
KR (1) KR101680396B1 (da)
CN (2) CN104945272A (da)
AR (1) AR075009A1 (da)
AU (1) AU2010205739B2 (da)
BR (1) BRPI1006150A2 (da)
CA (1) CA2747392C (da)
CY (1) CY1114407T1 (da)
DK (1) DK2387557T3 (da)
ES (1) ES2427972T3 (da)
HK (1) HK1214585A1 (da)
MX (1) MX2011007323A (da)
PE (1) PE20120111A1 (da)
PL (1) PL2387557T3 (da)
PT (1) PT2387557E (da)
RU (1) RU2503655C2 (da)
SI (1) SI2387557T1 (da)
TW (1) TWI389912B (da)
UY (1) UY32382A (da)
WO (1) WO2010081788A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104557597B (zh) * 2013-12-11 2017-08-04 浙江龙盛集团股份有限公司 一种3‑(n,n‑二取代)氨基乙酰苯胺类化合物的清洁生产方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831407B (en) * 1982-03-25 1983-11-30 Erba Farmitalia Substituted ethenyl derivatives of 1h-pyrazolo(1,5-a)pyrimidine and process for their preparation
US6399621B1 (en) * 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
JP2005516955A (ja) 2001-12-21 2005-06-09 バイエル・ヘルスケア・アクチェンゲゼルシャフト アロイル・ピリジノン化合物
ES2222813B1 (es) * 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
EP1736475A1 (en) 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates
US20080045547A1 (en) * 2006-07-07 2008-02-21 Lippa Arnold S Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use

Also Published As

Publication number Publication date
RU2503655C2 (ru) 2014-01-10
AU2010205739A1 (en) 2011-07-21
US8163903B2 (en) 2012-04-24
JP2012515149A (ja) 2012-07-05
CA2747392C (en) 2016-10-18
EP2387557B1 (en) 2013-06-19
HK1214585A1 (zh) 2016-07-29
AR075009A1 (es) 2011-03-02
UY32382A (es) 2010-07-30
WO2010081788A1 (en) 2010-07-22
SI2387557T1 (sl) 2013-12-31
CN104945272A (zh) 2015-09-30
CY1114407T1 (el) 2016-08-31
CA2747392A1 (en) 2010-07-22
AU2010205739B2 (en) 2015-12-10
TW201026704A (en) 2010-07-16
KR20110108346A (ko) 2011-10-05
MX2011007323A (es) 2011-07-29
US20110275809A1 (en) 2011-11-10
JP5507579B2 (ja) 2014-05-28
ES2427972T3 (es) 2013-11-05
TWI389912B (zh) 2013-03-21
BRPI1006150A2 (pt) 2018-01-16
KR101680396B1 (ko) 2016-11-28
EP2387557A1 (en) 2011-11-23
CN102282123A (zh) 2011-12-14
PT2387557E (pt) 2013-09-11
PL2387557T3 (pl) 2013-12-31
RU2011133958A (ru) 2013-02-20
PE20120111A1 (es) 2012-02-10

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