DK243886A - Middel til styret frigoerelse af et makromolekylaert medikament og fremgangsmaade til fremstilling af midlet - Google Patents

Middel til styret frigoerelse af et makromolekylaert medikament og fremgangsmaade til fremstilling af midlet Download PDF

Info

Publication number
DK243886A
DK243886A DK243886A DK243886A DK243886A DK 243886 A DK243886 A DK 243886A DK 243886 A DK243886 A DK 243886A DK 243886 A DK243886 A DK 243886A DK 243886 A DK243886 A DK 243886A
Authority
DK
Denmark
Prior art keywords
agent
procedure
manufacturing
controlled release
core
Prior art date
Application number
DK243886A
Other languages
English (en)
Other versions
DK243886D0 (da
DK171758B1 (da
Inventor
Mohamad D Shalati
Kallidaikuric Sivaramakrishnan
Original Assignee
Int Minerals & Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Minerals & Chem Corp filed Critical Int Minerals & Chem Corp
Publication of DK243886D0 publication Critical patent/DK243886D0/da
Publication of DK243886A publication Critical patent/DK243886A/da
Application granted granted Critical
Publication of DK171758B1 publication Critical patent/DK171758B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/07—Microporous membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Graft Or Block Polymers (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK243886A 1985-05-24 1986-05-23 Implantat til styret frigørelse af et makromolekylært lægemiddel og fremgangsmåde til fremstiling af implantatet DK171758B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/737,629 US4666704A (en) 1985-05-24 1985-05-24 Controlled release delivery system for macromolecules
US73762985 1985-05-24

Publications (3)

Publication Number Publication Date
DK243886D0 DK243886D0 (da) 1986-05-23
DK243886A true DK243886A (da) 1986-11-25
DK171758B1 DK171758B1 (da) 1997-05-12

Family

ID=24964638

Family Applications (1)

Application Number Title Priority Date Filing Date
DK243886A DK171758B1 (da) 1985-05-24 1986-05-23 Implantat til styret frigørelse af et makromolekylært lægemiddel og fremgangsmåde til fremstiling af implantatet

Country Status (15)

Country Link
US (1) US4666704A (da)
EP (1) EP0204476B1 (da)
JP (1) JP2755298B2 (da)
KR (1) KR940000001B1 (da)
CN (1) CN1020851C (da)
AT (1) ATE78155T1 (da)
AU (1) AU590565B2 (da)
CA (1) CA1277237C (da)
DE (1) DE3685992T2 (da)
DK (1) DK171758B1 (da)
ES (1) ES8707666A1 (da)
IE (1) IE59684B1 (da)
IL (1) IL78895A (da)
PT (1) PT82635B (da)
ZA (1) ZA863867B (da)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786501A (en) * 1985-07-15 1988-11-22 International Minerals & Chemical Corp. Cylindrical implants for the controlled release of growth hormones
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system
EP0270575A4 (en) * 1986-05-16 1988-10-20 Victoria State BIO-COMPATIBLE IMPLANTS.
AU601443B2 (en) * 1986-05-16 1990-09-13 Monash Medical Centre Biocompatible implants
US5342622A (en) * 1986-05-16 1994-08-30 The State Of Victoria Subdermal biocompatible implants
US4761289A (en) * 1986-10-10 1988-08-02 International Minerals & Chemical Corp. Sustained release implant and method for preparing same
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
US5073381A (en) * 1988-08-15 1991-12-17 University Of Akron Amphiphilic networks
SE8803822D0 (sv) * 1988-10-26 1988-10-26 Novel dosage form
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5141748A (en) * 1989-02-17 1992-08-25 Hoffmann-La Roche, Inc. Implant drug delivery device
ATE90203T1 (de) * 1989-03-17 1993-06-15 Pitman Moore Inc Kontrollierte, verzoegerte wirkstofffreisetzung von makromolekularen proteinen.
CH679207A5 (da) * 1989-07-28 1992-01-15 Debiopharm Sa
US5439688A (en) * 1989-07-28 1995-08-08 Debio Recherche Pharmaceutique S.A. Process for preparing a pharmaceutical composition
US5225205A (en) * 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
GB8928250D0 (en) * 1989-12-14 1990-02-21 Erba Carlo Spa Use of supercritical fluids to obtain porous sponges of biodegradable polymers
ES2062634T3 (es) * 1990-08-30 1994-12-16 Senju Pharma Co Composicion con liberacion controlada del farmaco.
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
US5516522A (en) * 1994-03-14 1996-05-14 Board Of Supervisors Of Louisiana State University Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same
US5660848A (en) * 1994-11-02 1997-08-26 The Population Council, Center For Biomedical Research Subdermally implantable device
GB2306325B (en) * 1994-11-25 1997-09-10 William Leslie Porter Bolus for supplying biologically beneficial substances to ruminant animals
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US7550005B2 (en) * 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US7896914B2 (en) * 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
SE505146C2 (sv) * 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
US20060025726A1 (en) * 1996-06-04 2006-02-02 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with pharmacologically active layer
US20060030826A1 (en) * 1996-06-04 2006-02-09 Vance Products Incorporated,d/b/a Cook Urological Incorporated Implantable medical device with anti-neoplastic drug
US6022554A (en) * 1997-12-15 2000-02-08 American Home Products Corporation Polymeric microporous film coated subcutaneous implant
KR20000022894A (ko) * 1998-09-05 2000-04-25 이승진 생분해성 고분자 미립자형 제제 및 그 제조방법
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6730349B2 (en) * 1999-04-19 2004-05-04 Scimed Life Systems, Inc. Mechanical and acoustical suspension coating of medical implants
ATE401095T1 (de) * 2000-05-26 2008-08-15 Frohwitter Bernhard Mittel zum erhalten und/oder korrigieren der blutglukosekonzentration
CA2451187C (en) * 2001-06-22 2012-08-14 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
AU2003256540B2 (en) 2002-07-12 2008-12-11 Cook Medical Technologies Llc Coated medical device
US8750983B2 (en) 2004-09-20 2014-06-10 P Tech, Llc Therapeutic system
EP1824460B1 (en) * 2004-11-10 2014-12-24 Tolmar Therapeutics, Inc. A stabilized polymeric delivery system
US8128952B2 (en) * 2005-01-12 2012-03-06 Clemson University Research Foundation Ligand-mediated controlled drug delivery
US20070141106A1 (en) * 2005-10-19 2007-06-21 Bonutti Peter M Drug eluting implant
US20070106271A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
KR101446813B1 (ko) * 2006-04-06 2014-10-01 뉴파쎄 인크. 도파민 연관된 상태의 치료를 위한 이식체
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
WO2018067882A1 (en) 2016-10-05 2018-04-12 Titan Pharmaceuticals, Inc. Implantable devices for drug delivery with reduced burst release
EP3691618A1 (en) 2017-10-06 2020-08-12 Foundry Therapeutics, Inc. Implantable depots for the controlled release of therapeutic agents
CN116650732A (zh) 2018-01-08 2023-08-29 铸造疗法股份有限公司 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法
US12458589B2 (en) 2018-05-12 2025-11-04 Foundry Therapeutics, Inc. Implantable polymer depots for the controlled release of therapeutic agents
CN111989068B (zh) * 2018-05-24 2024-10-25 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
CA3087238A1 (en) * 2018-05-24 2019-11-28 Celanese EVA Performance Polymers Corporation Implantable device for sustained release of a macromolecular drug compound
EP3843710A1 (en) 2018-08-28 2021-07-07 Foundry Therapeutics, Inc. Polymer implants
EP4329734A4 (en) 2021-04-26 2025-04-02 Celanese EVA Performance Polymers LLC Implantable device for the delayed release of a macromolecular drug compound

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987445A (en) * 1958-10-10 1961-06-06 Rohm & Haas Drug composition
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3558768A (en) * 1969-12-19 1971-01-26 Sterling Drug Inc Sustained release pharmaceutical compositions
DE2010416B2 (de) * 1970-03-05 1979-03-29 Hoechst Ag, 6000 Frankfurt Oral anwendbare Arzneiform mit Retardwirkung
AR206692A1 (es) * 1972-12-27 1976-08-13 Alza Corp Agente dispensador de liberacion sostenida de substancias activas
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US3923939A (en) * 1974-06-07 1975-12-02 Alza Corp Process for improving release kinetics of a monolithic drug delivery device
US4391797A (en) * 1977-01-05 1983-07-05 The Children's Hospital Medical Center Systems for the controlled release of macromolecules
US4127127A (en) * 1977-05-23 1978-11-28 Alza Corporation Therapeutic systems made from certain segmented copolyesters
US4148871A (en) * 1977-10-11 1979-04-10 Pitt Colin G Sustained subdermal delivery ofdrugs using poly(ε-caprolactone) and its copolymers
IN152178B (da) * 1978-05-08 1983-11-05 Pfizer
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
EP0013131A3 (en) * 1978-12-27 1981-01-07 Mundipharma A.G. Pharmaceutical composition in solid dosage form, and process for its production
JPS593962B2 (ja) * 1980-06-24 1984-01-27 日東電工株式会社 徐放性酵素製剤
JPS593963B2 (ja) * 1980-06-24 1984-01-27 日東電工株式会社 徐放性酵素製剤
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
US4377568A (en) * 1981-08-12 1983-03-22 Merck Sharp & Dohme (I.A.) Corp. Preparation of aqueous alcoholic dispersions of pH sensitive polymers and plasticizing agents and a method of enteric coating dosage forms using same

Also Published As

Publication number Publication date
CN86104226A (zh) 1987-02-25
US4666704A (en) 1987-05-19
EP0204476A1 (en) 1986-12-10
DK243886D0 (da) 1986-05-23
AU590565B2 (en) 1989-11-09
CA1277237C (en) 1990-12-04
IL78895A0 (en) 1986-09-30
EP0204476B1 (en) 1992-07-15
ATE78155T1 (de) 1992-08-15
DE3685992D1 (de) 1992-08-20
AU5767286A (en) 1986-11-27
DE3685992T2 (de) 1992-12-24
KR940000001B1 (ko) 1994-01-05
ZA863867B (en) 1987-01-28
KR860008776A (ko) 1986-12-18
JPS61277629A (ja) 1986-12-08
CN1020851C (zh) 1993-05-26
IE59684B1 (en) 1994-03-23
PT82635B (pt) 1988-07-29
PT82635A (en) 1986-06-01
IE861370L (en) 1986-11-24
JP2755298B2 (ja) 1998-05-20
IL78895A (en) 1991-01-31
DK171758B1 (da) 1997-05-12
ES555277A0 (es) 1987-08-16
ES8707666A1 (es) 1987-08-16

Similar Documents

Publication Publication Date Title
DK243886D0 (da) Middel til styret frigoerelse af et makromolekylaert medikament og fremgangsmaade til fremstilling af midlet
ES2001897A6 (es) Procedimiento para la fabricacion de una tableta de liberacion controlada
AU585377B2 (en) Controlled release pharmaceutical composition
NO20002547L (no) Poly(vinylamin)-baserte superabsorberende geler og fremgangsmÕte for fremstilling derav
DE3762867D1 (de) Mesomorpher polymerwirkstoff, verwendungsfaehig zur nichtlinearoptik.
NO167498C (no) Behandlet, halvgjennomtrengelig polymermembran, fremgangsmaate for fremstilling derav og anvendelse av membranen.
CA2290743A1 (en) Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
DE3580472D1 (de) Additiv zur erhoehung der leitfaehigkeit eines organischen polymers, eine aktiven wasserstoff enthaltende zusammensetzung mit diesem additiv sowie eine organische polymerzusammensetzung mit diesem additiv.
FR2360623B1 (da)
NO161124C (no) Polymerpulver for aa danne et enterisk belegg paa farmasoeytiske doseringsformer, og fremgangsmaate for fremstilling derav.
NO880231L (no) Fremgangsmaate for fremstilling av aromatiske heterocykliske polymerer.
DK0417572T3 (da) Forlænget frigivelse af små vandopløselige molekyler
FI906344A0 (fi) Kontrollerat frigoerande farmaceutiskt preparat.
DK0932391T3 (da) Fusogen liposomsammensætning og fremgangsmåde
MX9300851A (es) Un procedimiento para la preparacion de microcapsulas polimericas que contienen material biologicamente activo.
ES2058313T3 (es) Procedimiento para prevenir la formacion de incrustaciones de polimero.
ES2116308T3 (es) Dispositivo implantable a base de un material polimero, que contiene principios activos farmaceuticos, asi como procedimiento para su produccion.
ES2050717T3 (es) Membrana semipermeable organomineral y su procedimiento de fabricacion.
DK22190D0 (da) Asymmetrisk membran og fremgangsmaade til dens fremstilling samt membranens anvendelse
IE44540L (en) Controlled release tablet
ATE67226T1 (de) Feuchtdampfdurchlaessige materialien die segmentierte blockmultipolymere enthalten.
AU2000234134A1 (en) Graft polymeric membranes and ion-exchange membranes formed therefrom
ES8801334A1 (es) Procedimiento para la formacion de una membrana perfeccionada.
DK0395136T3 (da) Strålingsfølsom sammensætning og anvendelse deraf ved fremstillingen af elektrokemiske ion-sensorer
ES2146993T3 (es) Procedimiento para la fabricacion de componentes de cubas electroquimicas.

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed