DK2498756T4 - Tabletformuleringer af neratinibmaleat - Google Patents

Tabletformuleringer af neratinibmaleat Download PDF

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Publication number
DK2498756T4
DK2498756T4 DK10779339.0T DK10779339T DK2498756T4 DK 2498756 T4 DK2498756 T4 DK 2498756T4 DK 10779339 T DK10779339 T DK 10779339T DK 2498756 T4 DK2498756 T4 DK 2498756T4
Authority
DK
Denmark
Prior art keywords
neratinim
maleate
tablet formulations
formulations
tablet
Prior art date
Application number
DK10779339.0T
Other languages
English (en)
Other versions
DK2498756T3 (da
Inventor
Muhammad Ashraf
Krishnendu Ghosh
Chimanlall Goolcharran
Mainuddin Mahmud
Arwinder Singh Nagi
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43478191&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2498756(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Application granted granted Critical
Publication of DK2498756T3 publication Critical patent/DK2498756T3/da
Publication of DK2498756T4 publication Critical patent/DK2498756T4/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK10779339.0T 2009-11-09 2010-11-02 Tabletformuleringer af neratinibmaleat DK2498756T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25940309P 2009-11-09 2009-11-09
PCT/IB2010/054964 WO2011055303A1 (en) 2009-11-09 2010-11-02 Tablet formulations of neratinib maleate

Publications (2)

Publication Number Publication Date
DK2498756T3 DK2498756T3 (da) 2019-11-25
DK2498756T4 true DK2498756T4 (da) 2023-03-20

Family

ID=43478191

Family Applications (2)

Application Number Title Priority Date Filing Date
DK22169771.7T DK4066821T3 (da) 2009-11-09 2010-11-02 Tabletformuleringer af neratinibmaleat
DK10779339.0T DK2498756T4 (da) 2009-11-09 2010-11-02 Tabletformuleringer af neratinibmaleat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK22169771.7T DK4066821T3 (da) 2009-11-09 2010-11-02 Tabletformuleringer af neratinibmaleat

Country Status (23)

Country Link
US (2) US8518446B2 (da)
EP (4) EP3566697B1 (da)
JP (3) JP5835883B2 (da)
CN (2) CN103893140B (da)
AR (2) AR078952A1 (da)
AU (1) AU2010316683B2 (da)
CA (1) CA2780428C (da)
CY (1) CY1122330T1 (da)
DK (2) DK4066821T3 (da)
ES (3) ES2998766T3 (da)
FI (3) FI4066821T3 (da)
FR (1) FR25C1035I1 (da)
HR (2) HRP20192026T4 (da)
HU (3) HUE046606T2 (da)
LT (3) LT2498756T (da)
NZ (1) NZ599763A (da)
PL (2) PL4066821T3 (da)
PT (2) PT2498756T (da)
RS (2) RS59599B2 (da)
SI (2) SI2498756T2 (da)
SM (2) SMT202500153T1 (da)
TW (1) TWI466690B (da)
WO (1) WO2011055303A1 (da)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
CN108421044A (zh) 2005-02-03 2018-08-21 综合医院公司 治疗吉非替尼耐药性癌症的方法
BRPI0618042A2 (pt) 2005-11-04 2011-08-16 Wyeth Corp usos de uma rapamicina e de uma herceptina, produto, pacote farmacêutico, e, composição farmacêutica
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
US9439897B2 (en) 2007-11-06 2016-09-13 Immunolight, Llc Use of psoralen derivatives and combination therapy for treatment of cell proliferation disorders
CN102641270A (zh) 2008-06-17 2012-08-22 惠氏有限责任公司 含有hki-272和长春瑞滨的抗肿瘤组合
US8669273B2 (en) 2008-08-04 2014-03-11 Wyeth Llc Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine
IL264349B2 (en) 2009-04-06 2024-01-01 Wyeth Llc Regimen comprising neratinib for the treatment of cancer
NZ599762A (en) * 2009-11-09 2014-07-25 Wyeth Llc Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea
FI4066821T3 (fi) * 2009-11-09 2025-05-13 Wyeth Llc Neratinibimaleaatin tablettiformulaatioita
DK3738434T3 (da) 2011-12-28 2023-12-04 Global Blood Therapeutics Inc Mellemprodukter til opnåelse af substituerede benzaldehydforbindelser og fremgangsmåder til anvendelse deraf ved øgning af vævsoxygenering
WO2013102145A1 (en) 2011-12-28 2013-07-04 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
AU2014237330A1 (en) 2013-03-15 2015-09-17 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
BR112015021982B1 (pt) 2013-03-15 2022-12-13 Global Blood Therapeutics, Inc Compostos e seus usos para a modulação de hemoglobina
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
KR102280614B1 (ko) 2013-03-15 2021-07-21 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9818967B2 (en) * 2013-06-28 2017-11-14 Universal Display Corporation Barrier covered microlens films
CN104337782A (zh) * 2013-08-02 2015-02-11 山东新时代药业有限公司 一种甲磺酸伊马替尼片剂
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
SI3102208T2 (sl) 2014-02-07 2024-10-30 Global Blood Therapeutics, Inc. Kristalinični polimorf proste baze 2-hidroksi-6-((2-(1-izopropil-1H-pirazol-5-IL)piridin-3-IL)metoksi)- benzaldehida
ES2805008T3 (es) 2014-02-17 2021-02-10 Childrens Nat Medical Ct Procedimiento y sistema para proporcionar recomendaciones para la ejecución óptima de procedimientos quirúrgicos
DK3172209T3 (da) * 2014-07-25 2021-02-22 Novartis Ag Tabletformulering med 2-fluor-n-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamid
WO2017003951A1 (en) * 2015-06-29 2017-01-05 Phloronol, Inc. Solid pharmaceutical compositions of brown algae
US11020382B2 (en) 2015-12-04 2021-06-01 Global Blood Therapeutics, Inc. Dosing regimens for 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
CN106831710A (zh) * 2015-12-07 2017-06-13 常州爱诺新睿医药技术有限公司 一种无定型来那替尼或其药学上可接受的盐与药用辅料的固体分散体及其制备方法
CN106913529B (zh) * 2015-12-24 2020-12-04 江苏恒瑞医药股份有限公司 一种来那替尼或其可药用盐药物组合物的制备方法
CA2937365C (en) * 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
AR108435A1 (es) 2016-05-12 2018-08-22 Global Blood Therapeutics Inc Proceso para sintetizar 2-hidroxi-6-((2-(1-isopropil-1h-pirazol-5-il)-piridin-3-il)metoxi)benzaldehído
JP2019529534A (ja) * 2016-09-07 2019-10-17 セルジーン コーポレイション 錠剤組成物
TWI778983B (zh) * 2016-10-12 2022-10-01 美商全球血液治療公司 包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
CN118105392A (zh) * 2017-04-28 2024-05-31 自由生物有限公司 治疗特应性皮炎以及提高活性药物成分稳定性的制剂、方法、试剂盒和剂型
EP3701948A4 (en) * 2017-10-24 2021-08-25 Jiangsu Hengrui Medicine Co., Ltd. PHARMACEUTICAL COMPOSITION WITH QUINOLINE DERIVATIVE
EP3860975B1 (en) 2018-10-01 2023-10-18 Global Blood Therapeutics, Inc. Modulators of hemoglobin for the treatment of sickle cell disease
EP4096791A1 (en) 2020-01-31 2022-12-07 Nanocopoeia LLC Amorphous nilotinib microparticles and uses thereof
US20220378788A1 (en) * 2020-04-30 2022-12-01 Nanocopoeia, Llc Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib and in vitro characterization thereof
IL297776A (en) * 2020-04-30 2022-12-01 Nanocopoeia Llc Orally disintegrating tablets containing an amorphous solid dispersion of nalotinib
CA3186141A1 (en) * 2020-06-19 2021-12-23 Acerta Pharma B.V. Acalabrutinib maleate dosage forms
CN116211859A (zh) * 2021-12-03 2023-06-06 江苏奥赛康药业有限公司 一种含有马来酸奈拉替尼的药用组合物及其制备方法
TW202400135A (zh) * 2022-03-07 2024-01-01 美商健生醫藥公司 包含阿替卡普蘭之組成物
TW202345857A (zh) * 2022-03-08 2023-12-01 美商昂科斯克塞爾醫療有限責任公司 他波司他之穩定調配物
EP4682143A1 (en) 2023-03-10 2026-01-21 Convalife Pharmaceuticals Co., Ltd. Pharmaceutical composition containing egfr inhibitor, and preparation method therefor and use thereof
CN117298116A (zh) * 2023-08-08 2023-12-29 江苏晨泰医药科技有限公司 盐酸佐利替尼制剂
CN117427076B (zh) * 2023-12-05 2025-09-19 中国科学技术大学 来那替尼在制备预防或治疗动脉粥样硬化药物中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW442301B (en) * 1995-06-07 2001-06-23 Sanofi Synthelabo Pharmaceutical compositions containing irbesartan
US6002008A (en) 1997-04-03 1999-12-14 American Cyanamid Company Substituted 3-cyano quinolines
US6297258B1 (en) 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
US6288082B1 (en) 1998-09-29 2001-09-11 American Cyanamid Company Substituted 3-cyanoquinolines
US6384051B1 (en) 2000-03-13 2002-05-07 American Cyanamid Company Method of treating or inhibiting colonic polyps
US7399865B2 (en) * 2003-09-15 2008-07-15 Wyeth Protein tyrosine kinase enzyme inhibitors
AR046544A1 (es) * 2003-10-15 2005-12-14 Wyeth Corp Administracion oral de acido [2- (8,9 - dioxo - 2,6 - diazabiciclo [5.2.0] non -1 (7) - en - 2 - il ) alquil] fosfonico yderivados
US20050142192A1 (en) * 2003-10-15 2005-06-30 Wyeth Oral administration of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)alkyl] phosphonic acid and derivatives
CN101039952A (zh) * 2004-10-13 2007-09-19 惠氏公司 作为pi3k抑制剂的17-羟基渥曼青霉素类似物
WO2006085168A2 (en) * 2005-01-07 2006-08-17 Ranbaxy Laboratories Limited Solid oral dosage forms of ziprasidone containing colloidal silicone dioxide
DE602006012972D1 (de) * 2005-04-28 2010-04-29 Wyeth Corp Mikronisierte tanaproget zusammensetzungen und verfahren zu ihrer herstellung
PL1948180T3 (pl) * 2005-11-11 2013-09-30 Boehringer Ingelheim Int Terapia skojarzona raka polegająca na podawaniu inhibitorów EGFR/HER2
JP2007169273A (ja) * 2005-11-28 2007-07-05 Takeda Chem Ind Ltd 杵付着を改善した医薬製剤
JP2007211005A (ja) * 2006-01-16 2007-08-23 Ono Pharmaceut Co Ltd 固形製剤用組成物および固形製剤
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
KR20090104862A (ko) * 2007-01-12 2009-10-06 와이어쓰 정제내 정제 조성물
CL2008000280A1 (es) * 2007-02-01 2008-08-18 Takeda Pharmaceutical Composicion farmaceutica en forma de comprimido que contiene un granulo que comprende un principio activo que induce facilmente a un problema en la compresion y celulosa microcristalina y un auxiliar de compresion que contiene estearato de magnesio y
JP2009089982A (ja) * 2007-10-11 2009-04-30 Ohara Yakuhin Kogyo Kk 打錠用造粒物の造粒方法
US20090203709A1 (en) * 2008-02-07 2009-08-13 Abbott Laboratories Pharmaceutical Dosage Form For Oral Administration Of Tyrosine Kinase Inhibitor
RU2011152105A (ru) * 2009-07-02 2013-08-10 УАЙТ ЭлЭлСи Составы таблеток 3-цианохинолина и их применение
FI4066821T3 (fi) * 2009-11-09 2025-05-13 Wyeth Llc Neratinibimaleaatin tablettiformulaatioita

Also Published As

Publication number Publication date
HUS2500035I1 (hu) 2025-09-28
SMT202500153T1 (it) 2025-05-12
ES2998766T3 (en) 2025-02-21
JP2015091882A (ja) 2015-05-14
HRP20192026T1 (hr) 2020-02-07
HUE071632T2 (hu) 2025-09-28
TW201138774A (en) 2011-11-16
CN102724970A (zh) 2012-10-10
ES2757882T3 (es) 2020-04-30
PT4066821T (pt) 2025-06-03
WO2011055303A1 (en) 2011-05-12
RS66797B1 (sr) 2025-06-30
EP4066821B1 (en) 2025-03-05
LTPA2025531I1 (da) 2025-09-10
ES2757882T5 (es) 2023-05-10
CA2780428C (en) 2018-02-13
FIC20250029I1 (fi) 2025-08-29
HRP20192026T4 (hr) 2023-03-31
AU2010316683A1 (en) 2012-05-24
CN103893140B (zh) 2016-06-01
SI2498756T2 (sl) 2023-04-28
SI2498756T1 (sl) 2020-01-31
SMT201900632T1 (it) 2020-01-14
PT2498756T (pt) 2019-11-26
SI4066821T1 (sl) 2025-06-30
HUE046606T2 (hu) 2020-03-30
CN103893140A (zh) 2014-07-02
AR078952A1 (es) 2011-12-14
RS59599B1 (sr) 2020-01-31
EP3566697A1 (en) 2019-11-13
EP3566697B1 (en) 2024-09-11
JP5835883B2 (ja) 2015-12-24
HRP20250604T1 (hr) 2025-07-18
CY1122330T1 (el) 2021-01-27
LT2498756T (lt) 2019-12-10
FI4066821T3 (fi) 2025-05-13
US20110111018A1 (en) 2011-05-12
LT4066821T (lt) 2025-05-12
NZ599763A (en) 2014-06-27
FI2498756T4 (fi) 2023-03-22
AU2010316683B2 (en) 2015-10-08
FR25C1035I1 (fr) 2025-11-21
PL4066821T3 (pl) 2025-08-11
CN102724970B (zh) 2014-06-25
JP2011098964A (ja) 2011-05-19
ES3029208T3 (en) 2025-06-23
EP2498756B2 (en) 2023-02-15
EP2498756A1 (en) 2012-09-19
US20140004184A1 (en) 2014-01-02
US8518446B2 (en) 2013-08-27
RS59599B2 (sr) 2023-03-31
US8790708B2 (en) 2014-07-29
DK4066821T3 (da) 2025-04-14
JP2017075192A (ja) 2017-04-20
EP4066821A1 (en) 2022-10-05
DK2498756T3 (da) 2019-11-25
TWI466690B (zh) 2015-01-01
AR114143A2 (es) 2020-07-29
EP2498756B1 (en) 2019-09-04
PL2498756T5 (pl) 2023-04-17
PL2498756T3 (pl) 2020-03-31
EP4570242A3 (en) 2025-08-20
EP4570242A2 (en) 2025-06-18
CA2780428A1 (en) 2011-05-12

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