DK250090A - Alkylphyosphonoserin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse - Google Patents

Alkylphyosphonoserin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse Download PDF

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Publication number
DK250090A
DK250090A DK250090A DK250090A DK250090A DK 250090 A DK250090 A DK 250090A DK 250090 A DK250090 A DK 250090A DK 250090 A DK250090 A DK 250090A DK 250090 A DK250090 A DK 250090A
Authority
DK
Denmark
Prior art keywords
alkylphyosphonoserin
procedures
preparing
connection
pharmaceutical preparation
Prior art date
Application number
DK250090A
Other languages
English (en)
Other versions
DK250090D0 (da
DK167810B1 (da
Inventor
Hans Brachwitz
Reinhild Schoenfeld
Peter Langen
Friedrich Paltauf
Albin Hermetter
Original Assignee
Hafslund Nycomed Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DD31486888A external-priority patent/DD299727A7/de
Priority claimed from DD31835988A external-priority patent/DD289892A7/de
Application filed by Hafslund Nycomed Pharma filed Critical Hafslund Nycomed Pharma
Publication of DK250090D0 publication Critical patent/DK250090D0/da
Publication of DK250090A publication Critical patent/DK250090A/da
Application granted granted Critical
Publication of DK167810B1 publication Critical patent/DK167810B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/113—Esters of phosphoric acids with unsaturated acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4075—Esters with hydroxyalkyl compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK250090A 1988-04-19 1990-10-17 Alkylphyosphonoserin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse DK167810B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DD31486888 1988-04-19
DD31486888A DD299727A7 (de) 1988-04-19 1988-04-19 Alkyl- und alkenylphospho-l-serine, verfahren zu ihrer herstellung und verwendung
DD31835988A DD289892A7 (de) 1988-07-27 1988-07-27 Verfahren zur herstellung von alkylphosphonserinen
DD31835988 1988-07-27
PCT/EP1989/000393 WO1989010370A1 (fr) 1988-04-19 1989-04-13 Nouvelles alkylphosphono- et phosphoserines, procede pour leur preparation, et substances pharmaceutiques les contenant
EP8900393 1989-04-13

Publications (3)

Publication Number Publication Date
DK250090D0 DK250090D0 (da) 1990-10-17
DK250090A true DK250090A (da) 1990-10-17
DK167810B1 DK167810B1 (da) 1993-12-20

Family

ID=25748200

Family Applications (1)

Application Number Title Priority Date Filing Date
DK250090A DK167810B1 (da) 1988-04-19 1990-10-17 Alkylphyosphonoserin, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende en saadan forbindelse

Country Status (11)

Country Link
US (1) US5155099A (da)
EP (2) EP0338407B1 (da)
JP (1) JPH03504965A (da)
DE (1) DE58904595D1 (da)
DK (1) DK167810B1 (da)
ES (1) ES2056998T3 (da)
FI (1) FI91966C (da)
GR (1) GR3008598T3 (da)
HU (1) HU204278B (da)
NO (1) NO177712C (da)
WO (1) WO1989010370A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5117034A (en) * 1989-10-24 1992-05-26 Fuji Photo Film Co., Ltd. Phosphatidylserine derivatives
US5506217A (en) * 1991-04-25 1996-04-09 The University Of British Columbia Phosphonates as anti-cancer agents
EP0581793A1 (en) * 1991-04-25 1994-02-09 University Of British Columbia Phosphonates and phosphinates as anti-cancer, -inflammatory, -allergy and -myocarditis agents
US5369097A (en) * 1991-04-25 1994-11-29 The University Of British Columbia Phosphonates as anti-cancer agents
DE4132344A1 (de) * 1991-09-27 1993-04-01 Max Planck Gesellschaft Verfahren zur herstellung eines arzneimittels zur oralen oder topischen verabreichung bei der behandlung von leishmaniasis
US6254879B1 (en) 1991-09-27 2001-07-03 Max-Planck-Gessellschaft zun Förderung der Wissenschaften e.V. Methods of treating protozoal diseases
DE4229877C2 (de) * 1992-09-04 1994-09-15 Max Delbrueck Centrum Phospho- bzw. Phosphono-(N-acyl)-serine und ihre Herstellung
MXPA04002561A (es) * 2001-09-18 2004-07-30 Vasogen Ireland Ltd Entidades sistematicas que limitan la apoptosis y el uso de las mismas en el tratamiento medico.
US6878532B1 (en) 2003-04-28 2005-04-12 Sioux Biochemical, Inc. Method of producing phosphatidylserine
JP2009519296A (ja) * 2005-12-14 2009-05-14 ノボ・ノルデイスク・エー／エス ポリペプチド延長タグ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD238978A1 (de) * 1985-07-03 1986-09-10 Akad Wissenschaften Ddr Verfahren zur herstellung von 2-o-alkyl-i-des oxy-1-halogenglycero-3-phospho-l-serinen
DD238979A1 (de) * 1985-07-03 1986-09-10 Akad Wissenschaften Ddr Verfahren zur herstellung von o-alkylglycerophosphoserin-analogen
US4916249A (en) * 1985-07-03 1990-04-10 Hans Brachwitz Glycero-3(2)-phospho-L-serine derivatives and salts thereof
DD239405A1 (de) * 1985-07-15 1986-09-24 Akad Wissenschaften Ddr Verfahren zur herstellung von trifluoralkyl-glycerophospho-l-serinen
US4751320A (en) * 1985-11-27 1988-06-14 Kao Corporation Phosphoric ester and process for producing same
JPH064651B2 (ja) * 1985-11-27 1994-01-19 花王株式会社 リン酸エステルおよびその製造方法
DE3606633A1 (de) * 1986-02-28 1987-09-03 Max Planck Gesellschaft Neue phosphoverbindungen und diese enthaltende arzneimittel
JPH0761276B2 (ja) * 1986-11-14 1995-07-05 名糖産業株式会社 酵素法リン脂質−ｄ−セリン誘導体の製造法

Also Published As

Publication number Publication date
DK250090D0 (da) 1990-10-17
DK167810B1 (da) 1993-12-20
FI91966B (fi) 1994-05-31
ES2056998T3 (es) 1994-10-16
HUT51632A (en) 1990-05-28
DE58904595D1 (de) 1993-07-15
FI905051A0 (fi) 1990-10-15
EP0338407B1 (de) 1993-06-09
HU204278B (en) 1991-12-30
JPH03504965A (ja) 1991-10-31
NO904416D0 (no) 1990-10-12
US5155099A (en) 1992-10-13
WO1989010370A1 (fr) 1989-11-02
NO177712C (no) 1995-11-08
NO177712B (no) 1995-07-31
EP0338407A1 (de) 1989-10-25
FI91966C (fi) 1994-09-12
NO904416L (no) 1990-10-12
GR3008598T3 (da) 1993-10-29
EP0413700A1 (de) 1991-02-27

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed