DK264281A - Fremgangsmaade til fremtilling af indol- og indolindrivater - Google Patents

Fremgangsmaade til fremtilling af indol- og indolindrivater

Info

Publication number
DK264281A
DK264281A DK264281A DK264281A DK264281A DK 264281 A DK264281 A DK 264281A DK 264281 A DK264281 A DK 264281A DK 264281 A DK264281 A DK 264281A DK 264281 A DK264281 A DK 264281A
Authority
DK
Denmark
Prior art keywords
carbon atoms
alkyl
hydrogen
indoline derivatives
indol
Prior art date
Application number
DK264281A
Other languages
Danish (da)
English (en)
Inventor
M J Ashton
A W Bridge
R F Chapman
G Fenton
A H Loveless
D Riddell
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of DK264281A publication Critical patent/DK264281A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK264281A 1980-06-18 1981-06-16 Fremgangsmaade til fremtilling af indol- og indolindrivater DK264281A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8019948 1980-06-18

Publications (1)

Publication Number Publication Date
DK264281A true DK264281A (da) 1981-12-19

Family

ID=10514138

Family Applications (1)

Application Number Title Priority Date Filing Date
DK264281A DK264281A (da) 1980-06-18 1981-06-16 Fremgangsmaade til fremtilling af indol- og indolindrivater

Country Status (22)

Country Link
US (1) US4493843A (de)
EP (1) EP0042298B1 (de)
JP (1) JPS5728048A (de)
KR (1) KR850001470B1 (de)
AT (1) ATE9329T1 (de)
AU (1) AU539678B2 (de)
CA (1) CA1149811A (de)
DE (1) DE3165998D1 (de)
DK (1) DK264281A (de)
ES (4) ES503097A0 (de)
FI (1) FI811889A7 (de)
GB (1) GB2078736B (de)
GR (1) GR75701B (de)
HK (2) HK92684A (de)
HU (1) HU183480B (de)
IE (1) IE52102B1 (de)
IL (1) IL63110A (de)
MY (2) MY8500975A (de)
NZ (1) NZ197441A (de)
PH (1) PH16357A (de)
SG (2) SG68984G (de)
ZA (1) ZA814057B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015612A1 (en) * 1998-08-26 2000-03-23 Aventis Pharma Limited Aza-bicycles which modulate the inhibition of cell adhesion
GB9818641D0 (en) * 1998-08-26 1998-10-21 Rh Ne Poulenc Rorer Limited Chemical compounds
AU2050001A (en) * 1999-12-16 2001-06-25 Eli Lilly And Company Synthesis of indole-containing spla2 inhibitors
AU2003247390A1 (en) 2002-05-22 2003-12-12 Errant Gene Therapeutics, Llc. Histone deacetylase inhibitors based on alphachalcogenmethylcarbonyl compounds
DE602005012380D1 (de) * 2004-03-15 2009-03-05 Lilly Co Eli 4-(5-(aminomethyl)-indol-1-ylmethyl)benzamidderivate und verwandte verbindungen als opioidrezeptorantagonisten zur behandlung von fettleibigkeit
JP6217561B2 (ja) * 2014-08-21 2017-10-25 信越化学工業株式会社 新規オニウム塩化合物及びレジスト組成物並びにパターン形成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3076814A (en) * 1954-04-28 1963-02-05 Upjohn Co Novel process for the preparation of tryptophols and to novel compounds produced therein
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
US3992392A (en) * 1973-04-27 1976-11-16 The Ohio State University Research Foundation Synthesis of indoles from anilines and intermediates therein
US3901899A (en) * 1973-04-27 1975-08-26 Univ Ohio State Res Found Synthesis of indoles from anilines and intermediates therein
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
IE52102B1 (en) 1987-06-24
ES512704A0 (es) 1983-02-01
KR850001470B1 (ko) 1985-10-10
GB2078736A (en) 1982-01-13
ZA814057B (en) 1982-07-28
EP0042298B1 (de) 1984-09-12
SG73085G (en) 1986-05-02
MY8500975A (en) 1985-12-31
EP0042298A1 (de) 1981-12-23
ES8300091A1 (es) 1982-10-01
ATE9329T1 (de) 1984-09-15
PH16357A (en) 1983-09-05
ES8303332A1 (es) 1983-02-01
HU183480B (en) 1984-05-28
IE811344L (en) 1981-12-18
DE3165998D1 (de) 1984-10-18
MY8600409A (en) 1986-12-31
ES8305327A1 (es) 1983-04-01
ES512706A0 (es) 1983-04-01
CA1149811A (en) 1983-07-12
JPS5728048A (en) 1982-02-15
GB2078736B (en) 1984-03-07
ES8303333A1 (es) 1983-02-01
KR830006205A (ko) 1983-09-20
ES503097A0 (es) 1982-10-01
FI811889L (fi) 1981-12-19
IL63110A (en) 1986-10-31
FI811889A7 (fi) 1981-12-19
GR75701B (de) 1984-08-02
AU7186481A (en) 1981-12-24
AU539678B2 (en) 1984-10-11
US4493843A (en) 1985-01-15
HK92684A (en) 1984-11-30
HK92485A (en) 1985-11-29
NZ197441A (en) 1984-11-09
ES512705A0 (es) 1983-02-01
SG68984G (en) 1985-03-15

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