SG68984G - Indole and indoline derivatives - Google Patents

Indole and indoline derivatives

Info

Publication number
SG68984G
SG68984G SG689/84A SG68984A SG68984G SG 68984 G SG68984 G SG 68984G SG 689/84 A SG689/84 A SG 689/84A SG 68984 A SG68984 A SG 68984A SG 68984 G SG68984 G SG 68984G
Authority
SG
Singapore
Prior art keywords
carbon atoms
alkyl
hydrogen
indole
indoline derivatives
Prior art date
Application number
SG689/84A
Other languages
English (en)
Original Assignee
May & Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May & Baker Ltd filed Critical May & Baker Ltd
Publication of SG68984G publication Critical patent/SG68984G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5456—Arylalkanephosphonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG689/84A 1980-06-18 1984-09-25 Indole and indoline derivatives SG68984G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8019948 1980-06-18

Publications (1)

Publication Number Publication Date
SG68984G true SG68984G (en) 1985-03-15

Family

ID=10514138

Family Applications (2)

Application Number Title Priority Date Filing Date
SG689/84A SG68984G (en) 1980-06-18 1984-09-25 Indole and indoline derivatives
SG730/85A SG73085G (en) 1980-06-18 1985-10-05 Indole and indoline derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG730/85A SG73085G (en) 1980-06-18 1985-10-05 Indole and indoline derivatives

Country Status (22)

Country Link
US (1) US4493843A (de)
EP (1) EP0042298B1 (de)
JP (1) JPS5728048A (de)
KR (1) KR850001470B1 (de)
AT (1) ATE9329T1 (de)
AU (1) AU539678B2 (de)
CA (1) CA1149811A (de)
DE (1) DE3165998D1 (de)
DK (1) DK264281A (de)
ES (4) ES8300091A1 (de)
FI (1) FI811889A7 (de)
GB (1) GB2078736B (de)
GR (1) GR75701B (de)
HK (2) HK92684A (de)
HU (1) HU183480B (de)
IE (1) IE52102B1 (de)
IL (1) IL63110A (de)
MY (2) MY8500975A (de)
NZ (1) NZ197441A (de)
PH (1) PH16357A (de)
SG (2) SG68984G (de)
ZA (1) ZA814057B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9818641D0 (en) * 1998-08-26 1998-10-21 Rh Ne Poulenc Rorer Limited Chemical compounds
SK2612001A3 (en) * 1998-08-26 2001-11-06 Aventis Pharma Ltd Aza-bicycles which modulate the inhibition of cell adhesion
WO2001044184A1 (en) * 1999-12-16 2001-06-21 Eli Lilly And Company Synthesis of indole-containing spla2 inhibitors
AU2003247390A1 (en) 2002-05-22 2003-12-12 Errant Gene Therapeutics, Llc. Histone deacetylase inhibitors based on alphachalcogenmethylcarbonyl compounds
DE602005012380D1 (de) * 2004-03-15 2009-03-05 Lilly Co Eli 4-(5-(aminomethyl)-indol-1-ylmethyl)benzamidderivate und verwandte verbindungen als opioidrezeptorantagonisten zur behandlung von fettleibigkeit
JP6217561B2 (ja) * 2014-08-21 2017-10-25 信越化学工業株式会社 新規オニウム塩化合物及びレジスト組成物並びにパターン形成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3076814A (en) * 1954-04-28 1963-02-05 Upjohn Co Novel process for the preparation of tryptophols and to novel compounds produced therein
DE2237361A1 (de) * 1972-07-29 1974-02-14 Boehringer Mannheim Gmbh (5-indolyloxy)-essigsaeure-derivate und verfahren zur herstellung derselben
US3992392A (en) * 1973-04-27 1976-11-16 The Ohio State University Research Foundation Synthesis of indoles from anilines and intermediates therein
US3901899A (en) * 1973-04-27 1975-08-26 Univ Ohio State Res Found Synthesis of indoles from anilines and intermediates therein
US3950343A (en) * 1973-11-06 1976-04-13 Ayerst, Mckenna And Harrison Ltd. Pyrroloisoquinoline derivatives
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0042298A1 (de) 1981-12-23
IE52102B1 (en) 1987-06-24
FI811889L (fi) 1981-12-19
GB2078736A (en) 1982-01-13
IL63110A (en) 1986-10-31
ES8303333A1 (es) 1983-02-01
NZ197441A (en) 1984-11-09
ES8303332A1 (es) 1983-02-01
GB2078736B (en) 1984-03-07
ES503097A0 (es) 1982-10-01
ATE9329T1 (de) 1984-09-15
US4493843A (en) 1985-01-15
ES8305327A1 (es) 1983-04-01
KR850001470B1 (ko) 1985-10-10
HK92684A (en) 1984-11-30
HK92485A (en) 1985-11-29
ZA814057B (en) 1982-07-28
AU539678B2 (en) 1984-10-11
KR830006205A (ko) 1983-09-20
ES512705A0 (es) 1983-02-01
DE3165998D1 (de) 1984-10-18
PH16357A (en) 1983-09-05
FI811889A7 (fi) 1981-12-19
JPS5728048A (en) 1982-02-15
SG73085G (en) 1986-05-02
DK264281A (da) 1981-12-19
CA1149811A (en) 1983-07-12
AU7186481A (en) 1981-12-24
EP0042298B1 (de) 1984-09-12
ES8300091A1 (es) 1982-10-01
ES512704A0 (es) 1983-02-01
ES512706A0 (es) 1983-04-01
GR75701B (de) 1984-08-02
MY8500975A (en) 1985-12-31
MY8600409A (en) 1986-12-31
IE811344L (en) 1981-12-18
HU183480B (en) 1984-05-28

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