DK2806907T3 - Langstrakte vævsmatrix - Google Patents
Langstrakte vævsmatrix Download PDFInfo
- Publication number
- DK2806907T3 DK2806907T3 DK13702683.7T DK13702683T DK2806907T3 DK 2806907 T3 DK2806907 T3 DK 2806907T3 DK 13702683 T DK13702683 T DK 13702683T DK 2806907 T3 DK2806907 T3 DK 2806907T3
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Classifications
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/362—Skin, e.g. dermal papillae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
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- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Prostheses (AREA)
Claims (15)
1. Vævsbehandlingssammensætning, der omfatter: en samling af langstrakte elementer, uden en organiseret tertiær struktur, idet hvert langstrakt element omfatter en vævsmatrix, som mindst delvis er blevet decellulariseret, og hvor hvert langstrakt element har en fleksibel tredimensionel struktur, der omfatter en længdedimension, en breddedimension og en højdedimension, og hvor den ene dimension er væsentlig større end de to andre dimensioner, og aspektforholdet for den ene dimension sammenlignet med de to andre dimensioner er mindst 50:1.
2. Sammensætning ifølge krav 1, hvor vævsbehandlingsproduktet omfatter en delvis eller helt decellulariseret vævsmatrix fra mindst ét af væv fra menneske, ikke-human primat, gris, ko, hest, ged, får, hund, kat, kanin, marsvin, hoppemus, hamster, rotte og mus.
3. Sammensætning ifølge krav 2, hvor vævsbehandlingsproduktet omfatter mindst én porcin acellulær vævsmatrix.
4. Sammensætning ifølge et hvilket som helst af kravene 1-3, hvor vævsbehandlingsproduktet omfatter den delvis eller helt decellulariserede vævsmatrix fra mindst ét af væv fra knogle, hud, dermis, tarm, kar, urinblære, sene, ligament, muskel, fascia, åre, lever, hjerte, lunge, nyre eller brusk eller neurologisk væv.
5. Sammensætning ifølge krav 4, hvor vævsbehandlingsproduktet omfatter mindst én dermal acellulær vævsmatrix.
6. Sammensætning ifølge et hvilket som helst af kravene 1-5, hvor vævsbehandlingsproduktet omfatter en acellulær vævsmatrix fra én eller flere dyre- eller vævskilder.
7. Sammensætning ifølge et hvilket som helst af kravene 1-6, hvor vævsbehandlingsproduktet i det væsentlige mangler alle alpha-galactosegrupper.
8. Sammensætning ifølge et hvilket som helst af kravene 1-7, der endvidere omfatter én eller flere levedygtige og histokompatible celler.
9. Sammensætning ifølge krav 8, hvor den ene eller flere celler er pattedyrceller.
10. Sammensætning ifølge krav 9, hvor den ene eller flere celler er stamceller.
11. Sammensætning ifølge et hvilket som helst af kravene 1-10, der endvidere omfatter mindst én yderligere faktor, der er valgt blandt et antiinflammatorisk middel, et analgetikum, en cellevækstfaktor, en angiogen faktor, en differentieringsfaktor, et cytokin, et hormon og et kemokin.
12. Sammensætning ifølge krav 11, hvor den mindst ene yderligere faktor kodes af en nukleinsyresekvens, der er indeholdt i en ekspressionsvektor.
13. Sammensætning ifølge krav 12, hvor ekspressionsvektoren er indeholdt i én eller flere levedygtige og histokompatible celler.
14. Sammensætning ifølge et hvilket som helst af kravene 1-13, hvor vævsbehandlingsproduktet har en reduceret biobelastning eller helt mangler biobelastning.
15. Sammensætning ifølge et hvilket som helst af kravene 1-14, hvor hvert langstrakt element har én dimension, der er mindst 100 gange så stor som de to andre dimensioner.
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| US201261590035P | 2012-01-24 | 2012-01-24 | |
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| DK2806907T3 true DK2806907T3 (da) | 2019-02-18 |
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| EP (3) | EP2806907B1 (da) |
| AU (1) | AU2013212592B2 (da) |
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| DK (1) | DK2806907T3 (da) |
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2013
- 2013-01-17 EP EP13702683.7A patent/EP2806907B1/en active Active
- 2013-01-17 EP EP18206583.9A patent/EP3461508A1/en not_active Withdrawn
- 2013-01-17 EP EP20206235.2A patent/EP3797801A1/en not_active Withdrawn
- 2013-01-17 CA CA2861048A patent/CA2861048C/en active Active
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- 2013-01-17 CA CA3078056A patent/CA3078056A1/en not_active Abandoned
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|---|---|
| EP2806907B1 (en) | 2018-11-21 |
| ES2705823T3 (es) | 2019-03-26 |
| BR112014018047A8 (pt) | 2017-07-11 |
| EP3461508A1 (en) | 2019-04-03 |
| EP3797801A1 (en) | 2021-03-31 |
| US10327884B2 (en) | 2019-06-25 |
| AU2013212592B2 (en) | 2016-06-30 |
| US20160135940A1 (en) | 2016-05-19 |
| BR112014018047A2 (da) | 2017-06-20 |
| US9271821B2 (en) | 2016-03-01 |
| CA2861048A1 (en) | 2013-08-01 |
| EP2806907A1 (en) | 2014-12-03 |
| CA3078056A1 (en) | 2013-08-01 |
| AU2013212592A1 (en) | 2014-07-24 |
| BR112014018047B1 (pt) | 2019-11-26 |
| US20190262121A1 (en) | 2019-08-29 |
| US20130190893A1 (en) | 2013-07-25 |
| WO2013112350A1 (en) | 2013-08-01 |
| CA2861048C (en) | 2021-01-12 |
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