DK293890D0 - 3-oe2,(4-arylpiperazin1-yl)-ethoxylaap-cymen, derivater deraf, som er ortho-, meta- og paramonosubstituerede eller -disubstituerede paa phenylringen, fremgangsmaade til fremstilling af saadanne derivater samt laegemidler, hvori forbindelserne er til stede som det aktive middel - Google Patents

3-oe2,(4-arylpiperazin1-yl)-ethoxylaap-cymen, derivater deraf, som er ortho-, meta- og paramonosubstituerede eller -disubstituerede paa phenylringen, fremgangsmaade til fremstilling af saadanne derivater samt laegemidler, hvori forbindelserne er til stede som det aktive middel

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Publication number
DK293890D0
DK293890D0 DK293890A DK293890A DK293890D0 DK 293890 D0 DK293890 D0 DK 293890D0 DK 293890 A DK293890 A DK 293890A DK 293890 A DK293890 A DK 293890A DK 293890 D0 DK293890 D0 DK 293890D0
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DK
Denmark
Prior art keywords
pct
paze
paramonous
ethoxylap
cymene
Prior art date
Application number
DK293890A
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English (en)
Other versions
DK293890A (da
DK168071B1 (da
Inventor
Patrick Houziaux
Jean-Pierre Riffaud
Jean-Yves Lacolle
Bernard Danree
Original Assignee
Inst Rech Chim Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Inst Rech Chim Biolog filed Critical Inst Rech Chim Biolog
Publication of DK293890D0 publication Critical patent/DK293890D0/da
Publication of DK293890A publication Critical patent/DK293890A/da
Application granted granted Critical
Publication of DK168071B1 publication Critical patent/DK168071B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK293890A 1988-06-13 1990-12-11 3-oe2-(4-phenylpiperazin-l-yl)-ethoxyaa-p-cymen, derivater deraf, som er ortho-, meta- og para-monosubstituerede eller -disubstituerede paa phenylringen, fremgangsmaade til fremstilling af saadanne derivater, laegemidler, hvori forbindelserne er til stede som det aktive middel samt anvendelse af derivaterne til fremstilling af laegemidler DK168071B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8807864 1988-06-13
FR8807864A FR2632641B1 (fr) 1988-06-13 1988-06-13 ((aryl-4-piperazinyl-1)-2 ethoxy)-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif
FR8900298 1989-06-13
PCT/FR1989/000298 WO1989012634A1 (fr) 1988-06-13 1989-06-13 [(aryl-4-piperazinyl-1)-2 ethoxy]-3 p-cymene, les derives ortho, meta, para monosubstitues ou disubstitues sur le noyau phenyle dudit produit, le procede de preparation desdits derives, et les medicaments contenant lesdits composes comme principe actif

Publications (3)

Publication Number Publication Date
DK293890D0 true DK293890D0 (da) 1990-12-11
DK293890A DK293890A (da) 1990-12-11
DK168071B1 DK168071B1 (da) 1994-01-31

Family

ID=9367221

Family Applications (1)

Application Number Title Priority Date Filing Date
DK293890A DK168071B1 (da) 1988-06-13 1990-12-11 3-oe2-(4-phenylpiperazin-l-yl)-ethoxyaa-p-cymen, derivater deraf, som er ortho-, meta- og para-monosubstituerede eller -disubstituerede paa phenylringen, fremgangsmaade til fremstilling af saadanne derivater, laegemidler, hvori forbindelserne er til stede som det aktive middel samt anvendelse af derivaterne til fremstilling af laegemidler

Country Status (8)

Country Link
US (1) US5110816A (da)
EP (2) EP0445116A1 (da)
JP (1) JPH03505456A (da)
AT (1) ATE89276T1 (da)
DE (1) DE68906466T2 (da)
DK (1) DK168071B1 (da)
FR (1) FR2632641B1 (da)
WO (1) WO1989012634A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4410822A1 (de) * 1994-03-24 1995-09-28 Schering Ag Neue Piperidin-Derivate
DE69521687T2 (de) 1994-03-30 2001-10-25 Zeria Pharmaceutical Co., Ltd. 4-indol-1-yl-buttersäure derivate, deren herstellung und deren verwendung als inhibitoren für alpha1-adrenerge rezeptoren und testosteron 5alpha-reduktasen
ATE294778T1 (de) * 1995-01-23 2005-05-15 Daiichi Suntory Pharma Co Ltd Verbesserung oder heilung von durch ischämischen krankheiten hervorgerufenen symtomen und dafür verwendbare phenylpiperidinverbingungen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1349636A (fr) * 1962-02-26 1964-01-17 Soc Ind Fab Antibiotiques Sifa Nouveaux dérivés de la pipérazine, et procédé de préparation
CA967965A (en) * 1968-12-24 1975-05-20 Hoffmann-La Roche Limited Aromatic ethers and process for the manufacture thereof
FR2515648A1 (fr) * 1981-11-03 1983-05-06 Cortial Nouvelles (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique
FR2515647A1 (fr) * 1981-11-03 1983-05-06 Cortial Nouvelles imines derivees de (phenyl-4 piperazinylethyl)-2 anilines, leur methode de preparation et leur application therapeutique
EP0173634B1 (fr) * 1984-08-07 1988-08-31 Cortial S.A. Nouveaux dérivés d'(arylpipérazinyléthylaminoéthoxy)-4 phénol, leur méthode de préparation et leur application thérapeutique
FR2568878B1 (fr) * 1984-08-07 1986-11-21 Cortial Nouveaux derives de (phenylpiperazinylethylamine ethoxy)-4 phenol, leur methode de preparation et leur application therapeutique
EP0179009A1 (fr) * 1984-09-19 1986-04-23 Cortial S.A. Nouvelles n1-(aminoalcoxy)-4 isopropyl-5 phénoxy)-2 éthyl n4-phényl pipérazines, leur méthode de préparation et leur application thérapeutique
DE3604941A1 (de) * 1986-02-17 1987-08-20 Heumann Pharma Gmbh & Co Phenylpiperazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2595357B1 (fr) * 1986-03-04 1988-07-08 Irceba (piperidino-3 propoxy)-5 p.cymene, les derives acetyl, acetoxy et hydroxy dudit produit, les sels de ces produits, un procede de preparation desdits produits et les medicaments contenant au moins un de ces produits comme principe actif

Also Published As

Publication number Publication date
DK293890A (da) 1990-12-11
FR2632641B1 (fr) 1990-10-12
EP0347305A1 (fr) 1989-12-20
EP0347305B1 (fr) 1993-05-12
DK168071B1 (da) 1994-01-31
ATE89276T1 (de) 1993-05-15
WO1989012634A1 (fr) 1989-12-28
DE68906466D1 (de) 1993-06-17
JPH03505456A (ja) 1991-11-28
EP0445116A1 (fr) 1991-09-11
US5110816A (en) 1992-05-05
DE68906466T2 (de) 1993-09-09
FR2632641A1 (fr) 1989-12-15

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed