DK2958941T3 - Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom - Google Patents

Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom Download PDF

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Publication number
DK2958941T3
DK2958941T3 DK14706017.2T DK14706017T DK2958941T3 DK 2958941 T3 DK2958941 T3 DK 2958941T3 DK 14706017 T DK14706017 T DK 14706017T DK 2958941 T3 DK2958941 T3 DK 2958941T3
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DK
Denmark
Prior art keywords
periferted
microom
kir3dl2
cell
treatment
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DK14706017.2T
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English (en)
Inventor
Cécile Bonnafous
Hélène Sicard
Renaud Buffet
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Innate Pharma
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Publication of DK2958941T3 publication Critical patent/DK2958941T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57505—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the blood, e.g. leukaemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK14706017.2T 2013-02-20 2014-02-20 Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom DK2958941T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361766798P 2013-02-20 2013-02-20
US201361831809P 2013-06-06 2013-06-06
PCT/EP2014/053340 WO2014128221A1 (en) 2013-02-20 2014-02-20 A compound that specifically binds to kir3dl2 for use in the treatment of peripheral t cell lymphoma

Publications (1)

Publication Number Publication Date
DK2958941T3 true DK2958941T3 (da) 2019-06-24

Family

ID=50156759

Family Applications (3)

Application Number Title Priority Date Filing Date
DK14706017.2T DK2958941T3 (da) 2013-02-20 2014-02-20 Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom
DK21166926.2T DK3896088T3 (da) 2013-02-20 2014-02-20 Behandling af perifert t-cellelymfom
DK19163475.7T DK3521312T3 (da) 2013-02-20 2014-02-20 Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK21166926.2T DK3896088T3 (da) 2013-02-20 2014-02-20 Behandling af perifert t-cellelymfom
DK19163475.7T DK3521312T3 (da) 2013-02-20 2014-02-20 Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom

Country Status (9)

Country Link
US (5) US20160002345A1 (da)
EP (3) EP2958941B1 (da)
JP (1) JP6360077B2 (da)
CN (1) CN105026427B (da)
AU (1) AU2014220668B2 (da)
CA (1) CA2899241C (da)
DK (3) DK2958941T3 (da)
ES (2) ES2878749T3 (da)
WO (1) WO2014128221A1 (da)

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CA2881765C (en) 2012-09-19 2024-02-13 Innate Pharma Kir3dl2 binding agents
DK2958941T3 (da) 2013-02-20 2019-06-24 Innate Pharma Forbindelse, der binder specifikt til kir3dl2, til anvendelse til behandling af perifert t-cellelymfom
US20160130346A1 (en) * 2013-05-29 2016-05-12 Institut National De La Sante Et De La Recherche Medicale Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas
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CN117242093A (zh) * 2021-04-05 2023-12-15 先天制药公司 免疫组织化学方法和kir3dl2特异性试剂

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US20160130346A1 (en) 2013-05-29 2016-05-12 Institut National De La Sante Et De La Recherche Medicale Kir3dl2 is a biomarker and a therapeutic target useful for respectively preventing and treating a subset of cutaneous and non-cutaneous peripheral t-cell lymphomas
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JP7611834B2 (ja) 2019-01-22 2025-01-10 イナート・ファルマ・ソシエテ・アノニム Ｔ細胞リンパ腫の処置

Also Published As

Publication number Publication date
US20190127463A1 (en) 2019-05-02
EP3896088A1 (en) 2021-10-20
CA2899241C (en) 2023-03-28
JP6360077B2 (ja) 2018-07-18
US20170298132A1 (en) 2017-10-19
EP3896088B1 (en) 2025-07-23
CN105026427A (zh) 2015-11-04
AU2014220668A1 (en) 2015-08-20
EP3521312A1 (en) 2019-08-07
CA2899241A1 (en) 2014-08-28
US20160002345A1 (en) 2016-01-07
US12084498B2 (en) 2024-09-10
DK3521312T3 (da) 2021-06-28
US20210363248A1 (en) 2021-11-25
ES2878749T3 (es) 2021-11-19
US20250092130A1 (en) 2025-03-20
AU2014220668B2 (en) 2018-12-13
EP2958941B1 (en) 2019-04-10
EP2958941A1 (en) 2015-12-30
US10174112B2 (en) 2019-01-08
CN105026427B (zh) 2019-12-24
US11078275B2 (en) 2021-08-03
WO2014128221A1 (en) 2014-08-28
DK3896088T3 (da) 2025-09-29
ES2730011T3 (es) 2019-11-07
EP3521312B1 (en) 2021-04-07
JP2016513104A (ja) 2016-05-12

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