DK300090D0 - Fremgangsmaade til fremstilling af leadersekvenser - Google Patents

Fremgangsmaade til fremstilling af leadersekvenser

Info

Publication number
DK300090D0
DK300090D0 DK300090A DK300090A DK300090D0 DK 300090 D0 DK300090 D0 DK 300090D0 DK 300090 A DK300090 A DK 300090A DK 300090 A DK300090 A DK 300090A DK 300090 D0 DK300090 D0 DK 300090D0
Authority
DK
Denmark
Prior art keywords
preparing
procedure
leader sequences
leader
sequences
Prior art date
Application number
DK300090A
Other languages
English (en)
Inventor
Lars Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK300090A priority Critical patent/DK300090D0/da
Publication of DK300090D0 publication Critical patent/DK300090D0/da
Priority to NZ241011A priority patent/NZ241011A/en
Priority to KR1019930701890A priority patent/KR930703450A/ko
Priority to IE443391A priority patent/IE914433A1/en
Priority to CS931192A priority patent/CZ119293A3/cs
Priority to ZA919932A priority patent/ZA919932B/xx
Priority to SK62593A priority patent/SK62593A3/sk
Priority to IL100408A priority patent/IL100408A0/xx
Priority to PCT/DK1991/000396 priority patent/WO1992011378A1/en
Priority to EP92901668A priority patent/EP0563175A1/en
Priority to AU91348/91A priority patent/AU660161B2/en
Priority to CA002098731A priority patent/CA2098731A1/en
Priority to PT99848A priority patent/PT99848A/pt
Priority to JP4502056A priority patent/JPH06503957A/ja
Priority to HU9301801A priority patent/HUT68751A/hu
Priority to FI932831A priority patent/FI932831A0/fi
Priority to MX9102684A priority patent/MX9102684A/es
Priority to NO93932235A priority patent/NO932235L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Consolidation Of Soil By Introduction Of Solidifying Substances Into Soil (AREA)
  • Working Measures On Existing Buildindgs (AREA)
  • Prevention Of Electric Corrosion (AREA)
  • Bridges Or Land Bridges (AREA)
  • Building Environments (AREA)
DK300090A 1990-12-19 1990-12-19 Fremgangsmaade til fremstilling af leadersekvenser DK300090D0 (da)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (da) 1990-12-19 1990-12-19 Fremgangsmaade til fremstilling af leadersekvenser
NZ241011A NZ241011A (en) 1990-12-19 1991-12-17 Leader sequence for secreting heterologous polypeptides in yeast, vectors using it, yeast cells and process for producing heterologous polypeptides
FI932831A FI932831A0 (fi) 1990-12-19 1991-12-18 Ett foerfarande foer framstaellning av en syntetisk ledarsekvens
PCT/DK1991/000396 WO1992011378A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
EP92901668A EP0563175A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
CS931192A CZ119293A3 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leading peptide sequence
ZA919932A ZA919932B (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
SK62593A SK62593A3 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leader sequences
IL100408A IL100408A0 (en) 1990-12-19 1991-12-18 Construction of synthetic leader peptide sequences
KR1019930701890A KR930703450A (ko) 1990-12-19 1991-12-18 합성 선도 서열의 작제방법
IE443391A IE914433A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
AU91348/91A AU660161B2 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
CA002098731A CA2098731A1 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leader sequences
PT99848A PT99848A (pt) 1990-12-19 1991-12-18 Processo para a preparacao de sequencias lider sinteticas
JP4502056A JPH06503957A (ja) 1990-12-19 1991-12-18 合成リーダー配列の構成方法
HU9301801A HUT68751A (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
MX9102684A MX9102684A (es) 1990-12-19 1991-12-19 Metodo para construir secuencias de peptido lider, sinteticas.
NO93932235A NO932235L (no) 1990-12-19 1993-06-17 Fremgangsmaate ved fremstilling av syntetiske ledersekvenser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (da) 1990-12-19 1990-12-19 Fremgangsmaade til fremstilling af leadersekvenser

Publications (1)

Publication Number Publication Date
DK300090D0 true DK300090D0 (da) 1990-12-19

Family

ID=8118017

Family Applications (1)

Application Number Title Priority Date Filing Date
DK300090A DK300090D0 (da) 1990-12-19 1990-12-19 Fremgangsmaade til fremstilling af leadersekvenser

Country Status (17)

Country Link
EP (1) EP0563175A1 (da)
JP (1) JPH06503957A (da)
KR (1) KR930703450A (da)
AU (1) AU660161B2 (da)
CA (1) CA2098731A1 (da)
CZ (1) CZ119293A3 (da)
DK (1) DK300090D0 (da)
FI (1) FI932831A0 (da)
HU (1) HUT68751A (da)
IE (1) IE914433A1 (da)
IL (1) IL100408A0 (da)
MX (1) MX9102684A (da)
NZ (1) NZ241011A (da)
PT (1) PT99848A (da)
SK (1) SK62593A3 (da)
WO (1) WO1992011378A1 (da)
ZA (1) ZA919932B (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92601C (fi) * 1992-03-11 1994-12-12 Marja Makarow Menetelmä hyötyproteiinien erittämiseksi hiivoista
US5538863A (en) * 1993-07-01 1996-07-23 Immunex Corporation Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide
US5639642A (en) * 1994-06-16 1997-06-17 Novo Nordisk A/S Synthetic leader peptide sequences
ZA954983B (en) * 1994-06-17 1996-02-14 Novo Nordisk As N-terminally extended proteins expressed in yeast
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
EP2431462A3 (en) 1995-03-17 2012-05-23 Novozymes A/S Novel endoglucanases
EP1975177B1 (en) 1996-03-01 2011-04-13 Novo Nordisk A/S An appetite-suppressing peptide, its compositions and use
PT948538E (pt) * 1996-12-13 2008-08-05 Novartis Vaccines & Diagnostic Análise e separação de proteínas do factor de crescimento derivado de plaquetas
WO1999037793A1 (en) 1998-01-23 1999-07-29 Novo Nordisk A/S Process for making desired polypeptides in yeast
JP4795599B2 (ja) 1999-12-29 2011-10-19 ノボ ノルディスク アクティーゼルスカブ 酵母において改良された発酵収率を有するインスリン前駆体及びインスリン前駆体類似体の製造方法
AT410217B (de) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh Vektor und ein verfahren zur expression und selektion randomisierter peptid-sequenzen
ES2432967T3 (es) 2001-03-22 2013-12-05 Novo Nordisk Health Care Ag Derivados del Factor VII de coagulación
HUP0500060A3 (en) 2001-09-27 2010-01-28 Novo Nordisk Healthcare Ag Human coagulation factor vii polypeptides
CN101870729A (zh) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 凝固因子ⅶ多肽
EP1687428A1 (en) 2003-11-14 2006-08-09 Novo Nordisk A/S Processes for making acylated insulin
ES2369895T3 (es) 2003-12-03 2011-12-07 Novo Nordisk A/S Insulina monocatenaria.
WO2005078116A1 (fr) * 2004-01-16 2005-08-25 Qiuyun Liu Methode permettant d'isoler de peptides antibacteriens et peptides isoles
AU2006237329B2 (en) 2005-04-18 2012-04-12 Novo Nordisk A/S IL-21 variants
ATE513921T1 (de) 2005-08-16 2011-07-15 Novo Nordisk As Verfahren zur herstellung reifer insulinpolypeptide
JP5690047B2 (ja) 2005-09-14 2015-03-25 ノボ ノルディスク ヘルス ケア アーゲー ヒト凝固第ｖｉｉ因子ポリペプチド
JP5202338B2 (ja) 2006-02-27 2013-06-05 ノボ・ノルデイスク・エー／エス 新規インシュリン誘導体
WO2008037735A1 (en) 2006-09-27 2008-04-03 Novo Nordisk A/S Method for making maturated insulin polypeptides
US8575096B2 (en) 2007-08-13 2013-11-05 Novo Nordisk A/S Rapid acting insulin analogues
WO2009022006A1 (en) 2007-08-15 2009-02-19 Novo Nordisk A/S Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
AU2008288413B2 (en) 2007-08-15 2013-09-26 Novo Nordisk A/S Insulin analogues with an acyl and aklylene glycol moiety
WO2011089170A2 (en) 2010-01-22 2011-07-28 Novo Nordisk A/S Process for preparing fgf-21 with low degree of o-glycosylation
US20120107267A1 (en) 2009-03-11 2012-05-03 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
CA2767755C (en) 2009-07-17 2021-10-12 Rigshospitalet Inhibitors of complement activation
EP2504355B1 (en) 2009-11-25 2015-07-22 Novo Nordisk A/S Method for making polypeptides
ES2583259T3 (es) 2009-12-01 2016-09-20 Novo Nordisk A/S Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina
AU2011222883B2 (en) 2010-03-05 2016-05-26 Omeros Corporation Chimeric inhibitor molecules of complement activation
JP2013535467A (ja) * 2010-07-28 2013-09-12 スマートセルズ・インコーポレイテツド 組換えにより発現されたインスリンポリペプチドおよびその使用
PL2812024T3 (pl) 2012-02-09 2018-09-28 Var2 Pharmaceuticals Aps Celowanie glikanów siarczanu chondroityny
CN104704118A (zh) 2012-10-15 2015-06-10 诺和诺德保健Ag（股份有限公司） 凝血因子vii多肽
US20160115216A1 (en) 2013-06-07 2016-04-28 Novo Nordisk A/S Method for Making Mature Insulin Polypeptides
ES2700547T3 (es) 2014-02-28 2019-02-18 Novo Nordisk As Variantes del pro-péptido del factor de apareamiento alfa
CN112789504A (zh) 2018-07-13 2021-05-11 瓦克特诊断有限责任公司 使用重组疟疾蛋白var2csa分离胎儿来源的循环细胞

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK463887D0 (da) * 1987-09-07 1987-09-07 Novo Industri As Gaerleader
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
ATE135045T1 (de) * 1988-07-23 1996-03-15 Delta Biotechnology Ltd Sekretorische leader-sequenzen
DK105489D0 (da) * 1989-03-03 1989-03-03 Novo Nordisk As Polypeptid

Also Published As

Publication number Publication date
FI932831A7 (fi) 1993-06-18
WO1992011378A1 (en) 1992-07-09
KR930703450A (ko) 1993-11-30
PT99848A (pt) 1993-06-30
HU9301801D0 (en) 1993-10-28
MX9102684A (es) 1992-06-01
CA2098731A1 (en) 1992-06-19
JPH06503957A (ja) 1994-05-12
AU660161B2 (en) 1995-06-15
SK62593A3 (en) 1993-10-06
NZ241011A (en) 1993-04-28
FI932831L (fi) 1993-06-18
AU9134891A (en) 1992-07-22
IL100408A0 (en) 1992-09-06
HUT68751A (en) 1995-07-28
CZ119293A3 (en) 1994-02-16
ZA919932B (en) 1992-08-26
FI932831A0 (fi) 1993-06-18
IE914433A1 (en) 1992-07-01
EP0563175A1 (en) 1993-10-06

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