DK3110812T3 - Anti-amyloidforbindelser indeholdende benzofurazan - Google Patents

Anti-amyloidforbindelser indeholdende benzofurazan Download PDF

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Publication number
DK3110812T3
DK3110812T3 DK15755943.6T DK15755943T DK3110812T3 DK 3110812 T3 DK3110812 T3 DK 3110812T3 DK 15755943 T DK15755943 T DK 15755943T DK 3110812 T3 DK3110812 T3 DK 3110812T3
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Prior art keywords
amylide
benzofurazan
compounds containing
compounds
containing benzofurazan
Prior art date
Application number
DK15755943.6T
Other languages
English (en)
Inventor
Mark A Reed
Scott C Banfield
Christopher J Barden
Arun Yadav
Erhu Lu
Fan Wu
Thomas K Wood
Original Assignee
Treventis Corp
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Application filed by Treventis Corp filed Critical Treventis Corp
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Publication of DK3110812T3 publication Critical patent/DK3110812T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/081,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK15755943.6T 2014-02-27 2015-02-27 Anti-amyloidforbindelser indeholdende benzofurazan DK3110812T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461945697P 2014-02-27 2014-02-27
PCT/US2015/017939 WO2015131021A2 (en) 2014-02-27 2015-02-27 Anti-amyloid compounds containing benzofurazan

Publications (1)

Publication Number Publication Date
DK3110812T3 true DK3110812T3 (da) 2019-07-08

Family

ID=54009787

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15755943.6T DK3110812T3 (da) 2014-02-27 2015-02-27 Anti-amyloidforbindelser indeholdende benzofurazan

Country Status (19)

Country Link
US (1) US9938249B2 (da)
EP (1) EP3110812B1 (da)
JP (1) JP6663361B2 (da)
AU (1) AU2015222903B2 (da)
CA (1) CA2977360C (da)
CY (1) CY1121827T1 (da)
DK (1) DK3110812T3 (da)
ES (1) ES2734432T3 (da)
HR (1) HRP20191150T1 (da)
HU (1) HUE044999T2 (da)
IL (1) IL247428B (da)
LT (1) LT3110812T (da)
PL (1) PL3110812T3 (da)
PT (1) PT3110812T (da)
RS (1) RS58976B1 (da)
SI (1) SI3110812T1 (da)
SM (1) SMT201900387T1 (da)
TR (1) TR201910291T4 (da)
WO (1) WO2015131021A2 (da)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19643037A1 (de) 1996-10-18 1998-04-23 Boehringer Ingelheim Kg Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
MXPA04004443A (es) 2001-11-14 2004-08-11 Merck Patent Gmbh Derivados de pirazol.
US20050282818A1 (en) * 2004-06-22 2005-12-22 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
WO2012080729A2 (en) * 2010-12-14 2012-06-21 Electrophoretics Limited CASEIN KINASE 1δ (CK1δ) INHIBITORS
MX365851B (es) * 2012-08-24 2019-06-17 Treventis Corp Compuestos de benzofurazano anti-amiloides y metodos.

Also Published As

Publication number Publication date
WO2015131021A3 (en) 2015-11-19
US20170174641A1 (en) 2017-06-22
IL247428A0 (en) 2016-11-30
LT3110812T (lt) 2019-07-10
HUE044999T2 (hu) 2019-12-30
CA2977360C (en) 2022-09-27
US9938249B2 (en) 2018-04-10
EP3110812A4 (en) 2017-07-05
EP3110812A2 (en) 2017-01-04
PL3110812T3 (pl) 2019-10-31
IL247428B (en) 2020-01-30
EP3110812B1 (en) 2019-04-10
TR201910291T4 (tr) 2019-07-22
CA2977360A1 (en) 2015-09-03
HRP20191150T1 (hr) 2019-10-04
PT3110812T (pt) 2019-07-10
WO2015131021A2 (en) 2015-09-03
SI3110812T1 (sl) 2019-08-30
JP6663361B2 (ja) 2020-03-11
ES2734432T3 (es) 2019-12-05
JP2017506674A (ja) 2017-03-09
AU2015222903A1 (en) 2016-10-06
RS58976B1 (sr) 2019-08-30
AU2015222903B2 (en) 2018-02-01
CY1121827T1 (el) 2020-07-31
SMT201900387T1 (it) 2019-09-09

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