PL3110812T3 - Związki antyamyloidowe zawierające benzofurazan - Google Patents

Związki antyamyloidowe zawierające benzofurazan

Info

Publication number
PL3110812T3
PL3110812T3 PL15755943T PL15755943T PL3110812T3 PL 3110812 T3 PL3110812 T3 PL 3110812T3 PL 15755943 T PL15755943 T PL 15755943T PL 15755943 T PL15755943 T PL 15755943T PL 3110812 T3 PL3110812 T3 PL 3110812T3
Authority
PL
Poland
Prior art keywords
benzofurazan
compounds containing
amyloid compounds
amyloid
containing benzofurazan
Prior art date
Application number
PL15755943T
Other languages
English (en)
Inventor
Mark A Reed
Thomas K Wood
Scott C Banfield
Christopher J Barden
Arun Yadav
Erhu Lu
Fan Wu
Original Assignee
Treventis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Treventis Corp filed Critical Treventis Corp
Publication of PL3110812T3 publication Critical patent/PL3110812T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/08—1,2,5-Oxadiazoles; Hydrogenated 1,2,5-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL15755943T 2014-02-27 2015-02-27 Związki antyamyloidowe zawierające benzofurazan PL3110812T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461945697P 2014-02-27 2014-02-27
PCT/US2015/017939 WO2015131021A2 (en) 2014-02-27 2015-02-27 Anti-amyloid compounds containing benzofurazan
EP15755943.6A EP3110812B1 (en) 2014-02-27 2015-02-27 Anti-amyloid compounds containing benzofurazan

Publications (1)

Publication Number Publication Date
PL3110812T3 true PL3110812T3 (pl) 2019-10-31

Family

ID=54009787

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15755943T PL3110812T3 (pl) 2014-02-27 2015-02-27 Związki antyamyloidowe zawierające benzofurazan

Country Status (19)

Country Link
US (1) US9938249B2 (pl)
EP (1) EP3110812B1 (pl)
JP (1) JP6663361B2 (pl)
AU (1) AU2015222903B2 (pl)
CA (1) CA2977360C (pl)
CY (1) CY1121827T1 (pl)
DK (1) DK3110812T3 (pl)
ES (1) ES2734432T3 (pl)
HR (1) HRP20191150T1 (pl)
HU (1) HUE044999T2 (pl)
IL (1) IL247428B (pl)
LT (1) LT3110812T (pl)
PL (1) PL3110812T3 (pl)
PT (1) PT3110812T (pl)
RS (1) RS58976B1 (pl)
SI (1) SI3110812T1 (pl)
SM (1) SMT201900387T1 (pl)
TR (1) TR201910291T4 (pl)
WO (1) WO2015131021A2 (pl)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19643037A1 (de) 1996-10-18 1998-04-23 Boehringer Ingelheim Kg Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
MXPA04004443A (es) * 2001-11-14 2004-08-11 Merck Patent Gmbh Derivados de pirazol.
US20050282818A1 (en) 2004-06-22 2005-12-22 Rigel Pharmaceuticals, Inc. Ubiquitin ligase inhibitors
EP2651405A2 (en) * 2010-12-14 2013-10-23 Electrophoretics Limited Casein kinase 1 (ck1 ) inhibitors
BR112015003824B1 (pt) * 2012-08-24 2022-10-04 Treventis Corporation Composto, composição farmacêutica e uso do composto

Also Published As

Publication number Publication date
US20170174641A1 (en) 2017-06-22
JP2017506674A (ja) 2017-03-09
IL247428A0 (en) 2016-11-30
EP3110812B1 (en) 2019-04-10
IL247428B (en) 2020-01-30
SMT201900387T1 (it) 2019-09-09
TR201910291T4 (tr) 2019-07-22
CY1121827T1 (el) 2020-07-31
DK3110812T3 (da) 2019-07-08
EP3110812A4 (en) 2017-07-05
AU2015222903A1 (en) 2016-10-06
US9938249B2 (en) 2018-04-10
WO2015131021A3 (en) 2015-11-19
AU2015222903B2 (en) 2018-02-01
WO2015131021A2 (en) 2015-09-03
CA2977360C (en) 2022-09-27
HRP20191150T1 (hr) 2019-10-04
RS58976B1 (sr) 2019-08-30
CA2977360A1 (en) 2015-09-03
ES2734432T3 (es) 2019-12-05
EP3110812A2 (en) 2017-01-04
JP6663361B2 (ja) 2020-03-11
LT3110812T (lt) 2019-07-10
HUE044999T2 (hu) 2019-12-30
PT3110812T (pt) 2019-07-10
SI3110812T1 (sl) 2019-08-30

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