DK321688A - Heterocykliske forbindelser - Google Patents

Heterocykliske forbindelser

Info

Publication number
DK321688A
DK321688A DK321688A DK321688A DK321688A DK 321688 A DK321688 A DK 321688A DK 321688 A DK321688 A DK 321688A DK 321688 A DK321688 A DK 321688A DK 321688 A DK321688 A DK 321688A
Authority
DK
Denmark
Prior art keywords
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
DK321688A
Other languages
English (en)
Other versions
DK168600B1 (da
DK321688D0 (da
Inventor
Klaus Peter Boegesoe
Klaus Gundertofte Jensen
Ejner Knud Moltzen
Henrik Pedersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of DK321688D0 publication Critical patent/DK321688D0/da
Publication of DK321688A publication Critical patent/DK321688A/da
Application granted granted Critical
Publication of DK168600B1 publication Critical patent/DK168600B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK321688A 1987-06-24 1988-06-13 Piperidin-3-yl eller (1,2,5,6-tetrahydro-pyrid-3-yl)-substituerede heterocykliske forbindelser, farmaceutiske kompositioner deraf, og fremgangsmåder til deres fremstilling DK168600B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878714789A GB8714789D0 (en) 1987-06-24 1987-06-24 Heterocyclic compounds
GB8714789 1987-06-24

Publications (3)

Publication Number Publication Date
DK321688D0 DK321688D0 (da) 1988-06-13
DK321688A true DK321688A (da) 1988-12-25
DK168600B1 DK168600B1 (da) 1994-05-02

Family

ID=10619472

Family Applications (1)

Application Number Title Priority Date Filing Date
DK321688A DK168600B1 (da) 1987-06-24 1988-06-13 Piperidin-3-yl eller (1,2,5,6-tetrahydro-pyrid-3-yl)-substituerede heterocykliske forbindelser, farmaceutiske kompositioner deraf, og fremgangsmåder til deres fremstilling

Country Status (19)

Country Link
US (3) US4866077A (da)
EP (1) EP0296721B1 (da)
JP (1) JP2703268B2 (da)
AU (1) AU615917B2 (da)
BR (1) BR1100658A (da)
CA (1) CA1340458C (da)
DE (1) DE3881970T2 (da)
DK (1) DK168600B1 (da)
ES (1) ES2056928T3 (da)
FI (1) FI93356C (da)
GB (1) GB8714789D0 (da)
HK (1) HK84194A (da)
HU (1) HU210809A9 (da)
IE (1) IE61694B1 (da)
IL (1) IL86618A (da)
NO (1) NO174051C (da)
NZ (1) NZ224868A (da)
PT (1) PT87820B (da)
ZA (1) ZA884339B (da)

Families Citing this family (74)

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DE3877470T2 (de) * 1987-09-10 1993-06-24 Merck Sharp & Dohme Oxazole und thiazole zur behandlung seniler demenz.
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
ZA891113B (en) * 1988-02-19 1990-10-31 Lilly Co Eli Tetrazole excitatory amino acid receptor antagonists
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IT1229491B (it) * 1988-12-28 1991-09-03 Roussel Maestretti S P A Ora R Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
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US4902695A (en) * 1989-02-13 1990-02-20 Eli Lilly And Company Excitatory amino acid receptor antagonists
US5260311A (en) * 1989-02-22 1993-11-09 Novo Nordisk A/S Piperidine compounds and their use
US5328925A (en) * 1989-02-22 1994-07-12 Novo Nordisk A/S Piperidine compounds and their use
US5264444A (en) * 1989-02-22 1993-11-23 Novo Nordisk A/S Piperidine compounds and use
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
EP0402056A3 (en) * 1989-06-06 1991-09-04 Beecham Group p.l.c. Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
ATE136031T1 (de) * 1989-10-07 1996-04-15 Beecham Group Plc Azabizyklische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US5200419A (en) * 1990-05-21 1993-04-06 Warner-Lambert Company Substituted tetrazoles and derivatives thereof acting at muscarinic receptors
IE911994A1 (en) * 1990-07-03 1992-01-15 Akzo Nv 5-isothiazolamine derivatives
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US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5418240A (en) * 1990-08-21 1995-05-23 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
USRE35822E (en) * 1990-08-21 1998-06-09 Novo Nordisk A/S Heterocyclic compounds
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
US5376668A (en) * 1990-08-21 1994-12-27 Novo Nordisk A/S Heterocyclic compounds
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WO1992016239A1 (en) * 1991-03-13 1992-10-01 The Regents Of The University Of Minnesota Radiopharmaceutical agents for the detection of alzheimer's disease
IE922270A1 (en) * 1991-07-26 1993-01-27 Akzo Nv Pyrazole derivatives
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
WO1993014089A1 (en) * 1992-01-13 1993-07-22 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US5330994A (en) * 1992-03-24 1994-07-19 Warner-Lambert Company Tetrahydropyridine isoxazoline derivatives
AU678186B2 (en) * 1992-10-23 1997-05-22 Merck Sharp & Dohme Limited Dopamine receptor subtype ligands
US5753683A (en) * 1993-08-19 1998-05-19 Novo Nordisk A/S Antipsychotic method
US5612351A (en) * 1994-11-08 1997-03-18 Novo Nordisk A/S Method of treating urinary bladder dysfunctions
US5668148A (en) * 1995-04-20 1997-09-16 Merck & Co., Inc. Alpha1a adrenergic receptor antagonists
WO1997001555A1 (en) * 1995-06-29 1997-01-16 Novo Nordisk A/S Novel substituted azacyclic compounds
AU706594B2 (en) * 1995-11-06 1999-06-17 H. Lundbeck A/S Treatment of traumatic brain injury
ATE250055T1 (de) * 1996-04-24 2003-10-15 Novo Nordisk As Heterozyklische verbindungen, ihre herstellung und ihre anwendung
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
DE69825605T2 (de) 1997-05-29 2005-09-15 H. Lundbeck A/S Behandlung der schizophrenie und der psychose
AR013096A1 (es) * 1997-07-01 2000-12-13 Lundbeck & Co As H Sal de adicion de acido maleico de 5-(2-etil-2-h-tetrazol-5-il)-1-metil- 1,2,3,6-tetrahidropiridina, composicion farmaceutica que la contiene, su usoen terapia y metodo de preparacion de la misma.
JP2001518503A (ja) * 1997-10-02 2001-10-16 ハー・ルンドベック・アクチエゼルスカベット ５−（２−エチル−２ｈ−テトラゾール−５−イル）−１−メチル−１，２，３，６−テトラヒドロピリジンの粒状調合物
TR200100240T2 (tr) * 1998-07-27 2002-01-21 Eli Lilly And Company Anksiyete bozukluklarının tedavisi
AU6686700A (en) * 1999-08-23 2001-03-19 H. Lundbeck A/S Treatment of urinary incontinence
JP2003530438A (ja) * 2000-04-12 2003-10-14 スミスクライン・ビーチャム・コーポレイション 化合物および方法
SI1373263T1 (en) * 2001-04-05 2005-04-30 Torrent Pharmaceuticals Ltd Heterocyclic compounds for aging-related and diabetic vascular complications
US20030069597A1 (en) * 2001-10-10 2003-04-10 Scimed Life Systems, Inc. Loading tool
BR0214295A (pt) * 2001-11-19 2004-11-09 Elan Pharm Inc Composto, método para tratar um paciente que tem ou prevenir um paciente de adquirir uma doença ou condição, e, método para produzir um composto
KR20050085673A (ko) 2002-12-18 2005-08-29 에프엠씨 코포레이션 Ｎ-(치환된 아릴메틸)-4-(이치환된 메틸)피페리딘 및피페라진
WO2004058148A2 (en) * 2002-12-20 2004-07-15 Merck & Co., Inc. Mitotic kinesin inhibitors
WO2005080394A1 (en) * 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. 4-substituted piperidine derivatives
US20060224175A1 (en) * 2005-03-29 2006-10-05 Vrba Anthony C Methods and apparatuses for disposition of a medical device onto an elongate medical device
EP2275096A3 (en) 2005-08-26 2011-07-13 Braincells, Inc. Neurogenesis via modulation of the muscarinic receptors
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
WO2007047978A2 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by pde inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
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JP2011520905A (ja) 2008-05-15 2011-07-21 ザ・ユニバーシティ・オブ・トレド 向知性剤としてのムスカリンアゴニスト
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EP2427432A2 (en) * 2009-05-07 2012-03-14 Torrent Pharmaceuticals Limited Novel heterocyclic compounds
EP2593447B1 (de) 2010-07-15 2016-08-17 Bayer Intellectual Property GmbH 3-pyridyl-heteroarylcarboxamidverbindungen als schädlingsbekämpfungsmittel
BR112013009823A2 (pt) 2010-10-22 2016-07-05 Bayer Ip Gmbh novos compostos heterocíclicos como pesticidas
US9549928B2 (en) 2011-04-29 2017-01-24 The University Of Toledo Muscarinic agonists as enhancers of cognitive flexibility
CN103848850B (zh) * 2013-08-28 2016-03-23 沈阳东瑞精细化工有限公司 一种舒巴坦的制备方法
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US2659739A (en) 1950-04-14 1953-11-17 Eastman Kodak Co 1-hydroxy-4-beta-cyanopropylamino-anthraquinone and process for preparing same
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IL83275A (en) * 1986-09-08 1994-02-27 Novo Nordisk As Substituted 1, 2, 4- oxadiazolyl piperidine compounds, their preparation and pharmaceutical compositions containing them
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
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Also Published As

Publication number Publication date
JPS6422869A (en) 1989-01-25
USRE36374E (en) 1999-11-02
NZ224868A (en) 1990-07-26
FI883064A0 (fi) 1988-06-23
IE61694B1 (en) 1994-11-16
HU210809A9 (en) 1995-08-28
IL86618A (en) 1992-07-15
FI883064A7 (fi) 1988-12-25
PT87820B (pt) 1992-10-30
AU1828288A (en) 1989-01-05
NO174051B (no) 1993-11-29
EP0296721A3 (en) 1990-04-25
IE881631L (en) 1988-12-24
DE3881970T2 (de) 1993-11-11
DK168600B1 (da) 1994-05-02
JP2703268B2 (ja) 1998-01-26
EP0296721B1 (en) 1993-06-23
HK84194A (en) 1994-08-26
AU615917B2 (en) 1991-10-17
CA1340458C (en) 1999-03-23
IL86618A0 (en) 1988-11-30
FI93356C (fi) 1995-03-27
US4866077A (en) 1989-09-12
PT87820A (pt) 1989-05-31
DE3881970D1 (de) 1993-07-29
NO882799L (no) 1988-12-27
BR1100658A (pt) 1999-08-31
FI93356B (fi) 1994-12-15
ES2056928T3 (es) 1994-10-16
EP0296721A2 (en) 1988-12-28
ZA884339B (en) 1989-05-30
DK321688D0 (da) 1988-06-13
NO174051C (no) 1994-03-09
GB8714789D0 (en) 1987-07-29
NO882799D0 (no) 1988-06-23
US4925858A (en) 1990-05-15

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired