DK3250701T3 - Genmodificerede mikroorganismer med forbedret tolerance over for L-serin - Google Patents

Genmodificerede mikroorganismer med forbedret tolerance over for L-serin Download PDF

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DK3250701T3
DK3250701T3 DK16701783.9T DK16701783T DK3250701T3 DK 3250701 T3 DK3250701 T3 DK 3250701T3 DK 16701783 T DK16701783 T DK 16701783T DK 3250701 T3 DK3250701 T3 DK 3250701T3
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serine
genetically modified
improved tolerance
modified microorganisms
microorganisms
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DK16701783.9T
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Hemanshu Mundhada
Alex Toftgaard Nielsen
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Cysbio Aps
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DK16701783.9T 2015-01-27 2016-01-27 Genmodificerede mikroorganismer med forbedret tolerance over for L-serin DK3250701T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15152643 2015-01-27
PCT/EP2016/051728 WO2016120345A1 (en) 2015-01-27 2016-01-27 Genetically modified microorganisms having improved tolerance towards l-serine

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DK3250701T3 true DK3250701T3 (da) 2021-02-08

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DK16701783.9T DK3250701T3 (da) 2015-01-27 2016-01-27 Genmodificerede mikroorganismer med forbedret tolerance over for L-serin
DK16701661.7T DK3250700T3 (da) 2015-01-27 2016-01-27 Fremgangsmåde til fremstilling af L-serin under anvendelse af genmodificerede mikroorganismer, der mangler serin-nedbrydningspathways

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US (3) US10793826B2 (da)
EP (3) EP3839053A3 (da)
JP (2) JP6720194B2 (da)
CN (2) CN107406864B (da)
CA (2) CA2975010A1 (da)
DK (2) DK3250701T3 (da)
ES (2) ES2847673T3 (da)
HU (1) HUE050530T2 (da)
LT (1) LT3250701T (da)
MY (2) MY186949A (da)
PL (1) PL3250700T3 (da)
SI (1) SI3250701T1 (da)
WO (2) WO2016120326A1 (da)

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Publication number Priority date Publication date Assignee Title
DK3250701T3 (da) * 2015-01-27 2021-02-08 Cysbio Aps Genmodificerede mikroorganismer med forbedret tolerance over for L-serin
US10858676B2 (en) 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
CN110229853B (zh) * 2019-07-02 2021-06-01 武汉轻工大学 一种l-丝氨酸的制备方法
CN111019877B (zh) * 2019-12-31 2022-04-19 浙江工业大学 一种产l-半胱氨酸的基因工程菌、构建方法及应用
EP3960879A1 (en) * 2020-09-01 2022-03-02 Metabolic Explorer Microorganism and method for the improved production of alanine
WO2024013258A1 (en) 2022-07-15 2024-01-18 Cysbio Aps Production of cysteine or cystine from serine in fermentation medium
CA3225234A1 (en) 2022-08-04 2024-02-08 Metabolic Explorer Microorganism and method for the improved production of serine and/or cysteine
AU2023362566A1 (en) 2022-10-20 2025-04-24 Cysbio Aps Genetically modified host cells producing l-serine
CN120476203A (zh) 2023-01-09 2025-08-12 赢创运营有限公司 通过在微生物中减弱l-丝氨酸氨裂合酶活性来从丝氨酸发酵产生胍基乙酸(gaa)
CN120476204A (zh) 2023-01-09 2025-08-12 赢创运营有限公司 通过使用具有增强的l-丝氨酸羟甲基转移酶活性的微生物来从丝氨酸发酵产生胍基乙酸(gaa)
WO2024224355A1 (en) 2023-04-26 2024-10-31 Cysbio Aps A low dose formulation of l-serine for liver health and fatty liver diseases
KR102869970B1 (ko) * 2023-06-23 2025-10-14 씨제이제일제당 (주) 변이된 rbs 염기 서열을 포함하는 폴리뉴클리오티드, 상기 폴리뉴클레오티드를 포함하는 미생물, 및 이를 이용한 글리신 생산 방법
EP4556561A1 (en) 2023-11-14 2025-05-21 CysBio ApS Expression of biomolecules with improved promoter and tir
CN119662748A (zh) * 2024-12-30 2025-03-21 诸城市浩天药业有限公司 一种l-丝氨酸生产方法

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