DK328187A - Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmaaden

Info

Publication number
DK328187A
DK328187A DK328187A DK328187A DK328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A DK 328187 A DK328187 A DK 328187A
Authority
DK
Denmark
Prior art keywords
procedure
imidazopyridines
intermediates
preparation
Prior art date
Application number
DK328187A
Other languages
English (en)
Other versions
DK169505B1 (da
DK328187D0 (da
Inventor
Guy Rossey
David Long
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK328187D0 publication Critical patent/DK328187D0/da
Publication of DK328187A publication Critical patent/DK328187A/da
Application granted granted Critical
Publication of DK169505B1 publication Critical patent/DK169505B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK328187A 1986-06-27 1987-06-26 Fremgangsmåde til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmåden DK169505B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8609330 1986-06-27
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires

Publications (3)

Publication Number Publication Date
DK328187D0 DK328187D0 (da) 1987-06-26
DK328187A true DK328187A (da) 1987-12-28
DK169505B1 DK169505B1 (da) 1994-11-14

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
DK328187A DK169505B1 (da) 1986-06-27 1987-06-26 Fremgangsmåde til fremstilling af imidazopyridiner og mellemprodukter til brug ved fremgangsmåden

Country Status (21)

Country Link
US (1) US4794185A (da)
EP (1) EP0251859B1 (da)
JP (1) JPH0653740B2 (da)
KR (1) KR940006594B1 (da)
AR (1) AR243188A1 (da)
AT (1) ATE58537T1 (da)
AU (1) AU7477287A (da)
CA (1) CA1324138C (da)
DE (1) DE3766300D1 (da)
DK (1) DK169505B1 (da)
ES (1) ES2019646B3 (da)
FI (1) FI872850A7 (da)
FR (1) FR2600650B1 (da)
GR (1) GR3001118T3 (da)
HU (1) HU204826B (da)
IE (1) IE60467B1 (da)
IL (1) IL82982A (da)
NO (1) NO167392C (da)
NZ (1) NZ220853A (da)
PT (1) PT85188B (da)
ZA (1) ZA874643B (da)

Families Citing this family (47)

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ES2032455T3 (es) * 1986-01-22 1993-02-16 Synthelabo Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
EP1100508B8 (en) 1998-06-09 2004-01-07 Takeda Chemical Industries, Ltd. Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone and brotizolam for treating or preventing sleep disorders
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
ATE242241T1 (de) 1999-03-25 2003-06-15 Synthon Bv Imidazopyridinderivate und verfahren zu ihrer herstellung
DE60020814T2 (de) * 1999-03-25 2006-05-04 Synthon B.V. Zolpidem salze
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
WO2001078725A2 (en) 2000-04-13 2001-10-25 Synthon B.V. Modified release formulations containing a hypnotic agent
ES2239558T3 (es) * 2000-04-24 2007-04-01 Teva Pharmaceutical Industries Ltd. Hemitartrato de zolpidem micronizado.
EP1475093B1 (en) * 2000-04-24 2006-09-06 Teva Pharmaceutical Industries Ltd. Micronized Zolpidem hemitartrate
IT1318624B1 (it) 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
AU2000264428A1 (en) * 2000-08-17 2002-02-25 Cilag A.G. Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
WO2004007496A1 (en) * 2002-07-15 2004-01-22 Scinopharm Taiwan, Ltd. Process for the preparation of imidazo(1,2-a)pyridine-3-acetamides
ES2320758T3 (es) * 2002-12-18 2009-05-28 Mallinckrodt Inc. Sintesis de heteroaril acetamidas.
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
ES2336126T3 (es) * 2004-06-22 2010-04-08 Mallinckrodt, Inc. Sintesis de heteroarilacetamidas a partir de mezclas de reaccion que tienen un contenido reducido de agua.
US20080262025A1 (en) * 2004-07-16 2008-10-23 Yatendra Kumar Processes for the Preparation of Zolpidem and its Hemitartrate
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
AU2006297475A1 (en) * 2005-10-03 2007-04-12 Mallinckrodt Inc. Process for preparing zolpidem hemitartrate and tartrate polymorphs
EP1948134A2 (en) * 2005-10-17 2008-07-30 Mallinckrodt, Inc. Polymorph transformation of zolpidem in tablet matrix
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
ATE438381T1 (de) 2005-11-18 2009-08-15 Synhton B V Zolpidemtabletten
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
AU2007292848A1 (en) * 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法
CN114249668B (zh) * 2020-09-25 2024-08-23 鲁南制药集团股份有限公司 一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (da) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
ZA874643B (en) 1988-02-24
EP0251859B1 (fr) 1990-11-22
JPS638384A (ja) 1988-01-14
FI872850A7 (fi) 1987-12-28
NO167392C (no) 1991-10-30
HU204826B (en) 1992-02-28
HUT44547A (en) 1988-03-28
DK169505B1 (da) 1994-11-14
IL82982A (en) 1992-03-29
FR2600650A1 (fr) 1987-12-31
AR243188A1 (es) 1993-07-30
FI872850A0 (fi) 1987-06-26
NO167392B (no) 1991-07-22
NZ220853A (en) 1989-09-27
JPH0653740B2 (ja) 1994-07-20
EP0251859A2 (fr) 1988-01-07
IL82982A0 (en) 1987-12-20
US4794185A (en) 1988-12-27
EP0251859A3 (en) 1989-07-19
KR880000433A (ko) 1988-03-25
IE60467B1 (en) 1994-07-13
ES2019646B3 (es) 1991-07-01
GR3001118T3 (en) 1992-05-12
DE3766300D1 (de) 1991-01-03
ATE58537T1 (de) 1990-12-15
AU7477287A (en) 1988-01-07
KR940006594B1 (ko) 1994-07-23
NO872682L (no) 1987-12-28
PT85188B (pt) 1990-03-30
CA1324138C (en) 1993-11-09
FR2600650B1 (fr) 1988-09-09
DK328187D0 (da) 1987-06-26
NO872682D0 (no) 1987-06-26
PT85188A (fr) 1987-07-01
IE871723L (en) 1987-12-27

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired