DK330483D0 - Fremgangsmade til fremstilling af derivater af demycinosyltylosin (dmt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf - Google Patents

Fremgangsmade til fremstilling af derivater af demycinosyltylosin (dmt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf

Info

Publication number: DK330483D0
Authority: DK; Denmark
Prior art keywords: optionally substituted; alkanoyl; hydrogen; phenylacetyl; dmt
Prior art date: 1982-07-19

Application number

DK3304/83A

Other languages

Danish (da)

English (en)

Inventor

Herbert Andrew Kirst

John Eldon Toth

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-07-19

Filing date

1983-07-18

Publication date

1983-07-18

1983-07-18 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1983-07-18 Publication of DK330483D0 publication Critical patent/DK330483D0/da

Links

150000003839 salts Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
229910052799 carbon Inorganic materials 0.000 title 1
150000001721 carbon Chemical class 0.000 title 1
-1 -S-R4 Chemical group 0.000 abstract 11
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 4
ZVOOGERIHVAODX-QWWGUZMMSA-N 2-[(4r,5s,6s,7r,9r,11e,13e,15r,16r)-6-[(2r,3r,4r,5r,6r)-5-[(2s,4r,5s,6s)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-16-ethyl-4-hydroxy-15-(hydroxymethyl)-5,9,13-trimethyl-2,10-dioxo-1-oxacyclohexadeca-11,13-d Chemical class O=CC[C@H]1C[C@@H](C)C(=O)\C=C\C(\C)=C\[C@H](CO)[C@@H](CC)OC(=O)C[C@@H](O)[C@H](C)[C@H]1O[C@H]1[C@H](O)[C@@H](N(C)C)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(O)C2)[C@@H](C)O1 ZVOOGERIHVAODX-QWWGUZMMSA-N 0.000 abstract 2
239000003242 anti bacterial agent Substances 0.000 abstract 2
229940088710 antibiotic agent Drugs 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
ZVOOGERIHVAODX-UHFFFAOYSA-N O-demycinosyltylosin Natural products O=CCC1CC(C)C(=O)C=CC(C)=CC(CO)C(CC)OC(=O)CC(O)C(C)C1OC1C(O)C(N(C)C)C(OC2OC(C)C(O)C(C)(O)C2)C(C)O1 ZVOOGERIHVAODX-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000001246 bromo group Chemical group Br* 0.000 abstract 1
125000001309 chloro group Chemical group Cl* 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000001153 fluoro group Chemical group F* 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
125000002346 iodo group Chemical group I* 0.000 abstract 1
125000001786 isothiazolyl group Chemical group 0.000 abstract 1
125000000842 isoxazolyl group Chemical group 0.000 abstract 1
125000001715 oxadiazolyl group Chemical group 0.000 abstract 1
125000002971 oxazolyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003373 pyrazinyl group Chemical group 0.000 abstract 1
125000003226 pyrazolyl group Chemical group 0.000 abstract 1
125000002098 pyridazinyl group Chemical group 0.000 abstract 1
JUJWROOIHBZHMG-UHFFFAOYSA-O pyridinium Chemical compound C1=CC=[NH+]C=C1 JUJWROOIHBZHMG-UHFFFAOYSA-O 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
125000003831 tetrazolyl group Chemical group 0.000 abstract 1
125000001113 thiadiazolyl group Chemical group 0.000 abstract 1
125000000335 thiazolyl group Chemical group 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1
125000004306 triazinyl group Chemical group 0.000 abstract 1
125000001425 triazolyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Hydrogenated Pyridines (AREA)
Pyrane Compounds (AREA)
Liquid Crystal Substances (AREA)
Steroid Compounds (AREA)
Train Traffic Observation, Control, And Security (AREA)
Emergency Protection Circuit Devices (AREA)

DK3304/83A 1982-07-19 1983-07-18 Fremgangsmade til fremstilling af derivater af demycinosyltylosin (dmt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf DK330483D0 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/399,656 US4452784A (en)	1982-07-19	1982-07-19	C-23-Modified derivatives of DMT

Publications (1)

Publication Number	Publication Date
DK330483D0 true DK330483D0 (da)	1983-07-18

Family

ID=23580425

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK3304/83A DK330483D0 (da)	1982-07-19	1983-07-18	Fremgangsmade til fremstilling af derivater af demycinosyltylosin (dmt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf

Country Status (19)

Country	Link
US (1)	US4452784A (de)
EP (1)	EP0099746B1 (de)
JP (1)	JPS5931796A (de)
KR (1)	KR850000966B1 (de)
AT (1)	ATE23047T1 (de)
AU (1)	AU1693583A (de)
CA (1)	CA1202964A (de)
DD (1)	DD210059A5 (de)
DE (1)	DE3367104D1 (de)
DK (1)	DK330483D0 (de)
ES (1)	ES8504841A1 (de)
FI (1)	FI832604A7 (de)
GB (1)	GB2123827B (de)
GR (1)	GR78387B (de)
NZ (1)	NZ204940A (de)
PH (1)	PH19727A (de)
PL (1)	PL243091A1 (de)
PT (1)	PT77040A (de)
ZA (1)	ZA835216B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58219197A (ja) *	1982-06-15	1983-12-20	Sanraku Inc	マクロライド系抗生物質の誘導体
US4436729A (en) *	1982-06-30	1984-03-13	Schering Corporation	23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use
US4629786A (en) *	1983-02-28	1986-12-16	Eli Lilly And Company	C-20- and C-23 modified macrolide derivatives
US4656258A (en) *	1983-03-03	1987-04-07	Eli Lilly And Company	Macrocin derivatives
JPS62103098A (ja) *	1985-05-13	1987-05-13	Microbial Chem Res Found	タイロシン誘導体
PT87417B (pt) *	1987-05-06	1992-08-31	Adir	Processo para a preparacao de novos compostos macrolidos

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE667952A (de) *	1964-08-05
US4358584A (en) *	1979-05-23	1982-11-09	Eli Lilly And Company	Antibiotics A6888C and A6888X
JPS56122397A (en) *	1980-02-29	1981-09-25	Satoshi Omura	Marcolides
ZA813578B (en) *	1980-06-12	1983-01-26	Lilly Co Eli	Macrolide antibiotics
US4321362A (en) *	1980-06-12	1982-03-23	Eli Lilly And Company	De(mycinosyloxy)tylosin and process for its production
US4438109A (en) *	1980-07-25	1984-03-20	Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai	Tylosin derivatives
US4304856A (en) *	1980-11-10	1981-12-08	Eli Lilly And Company	Process for producing 20-dihydro-20-deoxy-23-demycinosyltylosin
US4341770A (en) *	1981-04-20	1982-07-27	Eli Lilly And Company	Method of controlling ureaplasma infections
US4341771A (en) *	1981-04-20	1982-07-27	Eli Lilly And Company	Method of controlling Pasteurella infections
AU551142B2 (en) *	1981-07-09	1986-04-17	Zaidan Hojin Biseibutsu Kagaku Kenkyukai	Tylosin derivatives
JPS58219197A (ja) *	1982-06-15	1983-12-20	Sanraku Inc	マクロライド系抗生物質の誘導体
US4436729A (en) *	1982-06-30	1984-03-13	Schering Corporation	23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use

1982
- 1982-07-19 US US06/399,656 patent/US4452784A/en not_active Expired - Fee Related
1983
- 1983-07-18 ZA ZA835216A patent/ZA835216B/xx unknown
- 1983-07-18 CA CA000432587A patent/CA1202964A/en not_active Expired
- 1983-07-18 GR GR71960A patent/GR78387B/el unknown
- 1983-07-18 KR KR1019830003274A patent/KR850000966B1/ko not_active Expired
- 1983-07-18 PT PT77040A patent/PT77040A/pt unknown
- 1983-07-18 DK DK3304/83A patent/DK330483D0/da not_active Application Discontinuation
- 1983-07-18 FI FI832604A patent/FI832604A7/fi not_active Application Discontinuation
- 1983-07-18 AU AU16935/83A patent/AU1693583A/en not_active Abandoned
- 1983-07-18 AT AT83304153T patent/ATE23047T1/de not_active IP Right Cessation
- 1983-07-18 ES ES524197A patent/ES8504841A1/es not_active Expired
- 1983-07-18 EP EP83304153A patent/EP0099746B1/de not_active Expired
- 1983-07-18 PH PH29239A patent/PH19727A/en unknown
- 1983-07-18 GB GB08319306A patent/GB2123827B/en not_active Expired
- 1983-07-18 NZ NZ204940A patent/NZ204940A/en unknown
- 1983-07-18 JP JP58131793A patent/JPS5931796A/ja active Pending
- 1983-07-18 DE DE8383304153T patent/DE3367104D1/de not_active Expired
- 1983-07-19 DD DD83253195A patent/DD210059A5/de unknown
- 1983-07-19 PL PL24309183A patent/PL243091A1/xx unknown

Also Published As

Publication number	Publication date
PT77040A (en)	1983-08-01
US4452784A (en)	1984-06-05
FI832604A0 (fi)	1983-07-18
GB2123827B (en)	1986-07-30
ES524197A0 (es)	1985-05-01
KR840005462A (ko)	1984-11-12
PL243091A1 (en)	1984-07-16
AU1693583A (en)	1984-01-26
JPS5931796A (ja)	1984-02-20
GB8319306D0 (en)	1983-08-17
KR850000966B1 (ko)	1985-07-02
EP0099746A1 (de)	1984-02-01
GR78387B (de)	1984-09-26
EP0099746B1 (de)	1986-10-22
PH19727A (en)	1986-06-17
DE3367104D1 (en)	1986-11-27
FI832604A7 (fi)	1984-01-20
ES8504841A1 (es)	1985-05-01
GB2123827A (en)	1984-02-08
CA1202964A (en)	1986-04-08
DD210059A5 (de)	1984-05-30
ATE23047T1 (de)	1986-11-15
ZA835216B (en)	1984-03-28
NZ204940A (en)	1985-11-08

Legal Events

Date	Code	Title	Description
1983-12-23	ATS	Application withdrawn

Publication	Publication Date	Title
DK330383D0 (da)	1983-07-18	Fremgangsmade til fremstilling af derivater af s-o-mycaminosyltolonid (omt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf
DK330483D0 (da)	1983-07-18	Fremgangsmade til fremstilling af derivater af demycinosyltylosin (dmt) modificeret ved carbonatom nr. 23 eller et syreadditionssalt deraf
DE59109039D1 (de)	1998-09-17	Cyclohexenonoximether, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung als Herbizide
CH610903A5 (en)	1979-05-15	Process for the preparation of cephalosporanic acid derivatives
SE7908428L (sv)	1980-04-19	Nya minoglykosider
PT73280A (de)	1981-07-01	Neue imidazol-derivate verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praparate
DE68929310T2 (de)	2002-05-02	3-(Substituierte)-1-Carba(dethia)-3-cephemverbindungen und Cephalosporine und ein Verfahren zu ihrer Herstellung
DK149347C (da)	1986-10-20	Fremgangsmaade til fremstilling af insulinpraeparater med krystaller med 2-zn-struktur
NO933170L (no)	1993-11-05	Heterocykliske forbindelser
SE8801945L (sv)	1988-11-30	Nya 5-metoxi- aklylammonium- tetrahydrofuraner och -tetrahydrotiofener
DK82583D0 (da)	1983-02-23	Furyloxazolyleddikesyrederivater og fremgangsmader til fremstilling deraf
IE890905L (en)	1989-09-23	A process for preparing 3-unsubstituted cephalosporins and 1-carba(dethia) cephalosporins
DK181183A (da)	1984-10-26	Cykliske imidatestere og fremgangsmaade til fremstilling deraf
SE8205482D0 (sv)	1982-09-24	Nya mellanprodukter for framstellning av antibakteriella cefalosporinsyror
JPS5283784A (en)	1977-07-12	7-substituted alkaneamide-3-substituted-3-cephem-4-carboxylic acid, it s derivative and salt
JPS5467036A (en)	1979-05-30	Cephalosporin preparation for oral administration
JPS5283862A (en)	1977-07-13	7-methoxycephalosporin derivatives
KR790000748B1 (en)	1979-06-29	Process for producing substituted oxirane compounds
JPS5793967A (en)	1982-06-11	Preparation of piperazine derivative
ATE36536T1 (de)	1988-09-15	Phosphoroimidate.