DK3464266T3 - Substituerede indazoler, der er anvendelige til behandling og forebyggelse af allergiske og/eller inflammatoriske sygdomme hos dyr - Google Patents

Substituerede indazoler, der er anvendelige til behandling og forebyggelse af allergiske og/eller inflammatoriske sygdomme hos dyr Download PDF

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Publication number
DK3464266T3
DK3464266T3 DK17725976.9T DK17725976T DK3464266T3 DK 3464266 T3 DK3464266 T3 DK 3464266T3 DK 17725976 T DK17725976 T DK 17725976T DK 3464266 T3 DK3464266 T3 DK 3464266T3
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DK
Denmark
Prior art keywords
allergic
animals
prevention
treatment
inflammatory diseases
Prior art date
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DK17725976.9T
Other languages
English (en)
Inventor
Gerald Beddies
Adrian Foster
Ulrich Bothe
Nicole Schmidt
Ulf Bömer
Reinhard Nubbemeyer
Maria De Lourdes Mottier
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Bayer Animal Health Gmbh
Bayer Pharma AG
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Application filed by Bayer Animal Health Gmbh, Bayer Pharma AG filed Critical Bayer Animal Health Gmbh
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Publication of DK3464266T3 publication Critical patent/DK3464266T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK17725976.9T 2016-06-01 2017-05-29 Substituerede indazoler, der er anvendelige til behandling og forebyggelse af allergiske og/eller inflammatoriske sygdomme hos dyr DK3464266T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16172544 2016-06-01
PCT/EP2017/062876 WO2017207481A1 (en) 2016-06-01 2017-05-29 Substituted indazoles ueful for treatment and prevention of allergic and/or inflammatory diseases in animals

Publications (1)

Publication Number Publication Date
DK3464266T3 true DK3464266T3 (da) 2021-11-22

Family

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DK17725976.9T DK3464266T3 (da) 2016-06-01 2017-05-29 Substituerede indazoler, der er anvendelige til behandling og forebyggelse af allergiske og/eller inflammatoriske sygdomme hos dyr

Country Status (25)

Country Link
US (3) US20200216413A1 (da)
EP (1) EP3464266B1 (da)
JP (1) JP7004677B2 (da)
KR (1) KR102547834B1 (da)
CN (3) CN119367364A (da)
AU (1) AU2017272505B9 (da)
BR (1) BR112018074927A2 (da)
CA (1) CA3025847A1 (da)
CL (1) CL2018003432A1 (da)
CO (1) CO2018013029A2 (da)
DK (1) DK3464266T3 (da)
DO (1) DOP2018000262A (da)
ES (1) ES2898771T3 (da)
IL (1) IL263132B (da)
MX (1) MX394560B (da)
MY (1) MY199070A (da)
PH (1) PH12018502530A1 (da)
PL (1) PL3464266T3 (da)
PT (1) PT3464266T (da)
RU (1) RU2743170C2 (da)
SG (1) SG11201809470RA (da)
SI (1) SI3464266T1 (da)
TW (1) TWI781935B (da)
UA (1) UA124237C2 (da)
WO (1) WO2017207481A1 (da)

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UA124237C2 (uk) 2016-06-01 2021-08-11 Байєр Енімал Хелс Гмбх Заміщені індазоли, придатні для лікування і попередження алергійних і/або запальних захворювань у тварин
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CL2018003432A1 (es) 2019-03-22
RU2018145860A3 (da) 2020-07-09
US20260085057A1 (en) 2026-03-26
JP7004677B2 (ja) 2022-01-21
PH12018502530A1 (en) 2019-10-21
CN119367364A (zh) 2025-01-28
JP2019520348A (ja) 2019-07-18
EP3464266A1 (en) 2019-04-10
UA124237C2 (uk) 2021-08-11
EP3464266B1 (en) 2021-10-20
TW201808933A (zh) 2018-03-16
MX2018014899A (es) 2019-04-24
SG11201809470RA (en) 2018-11-29
PL3464266T3 (pl) 2022-01-24
AU2017272505A1 (en) 2018-11-15
WO2017207481A1 (en) 2017-12-07
US12459916B2 (en) 2025-11-04
CN109219603A (zh) 2019-01-15
WO2017207481A8 (en) 2018-11-22
CN120531733A (zh) 2025-08-26
AU2017272505B9 (en) 2021-10-28
SI3464266T1 (sl) 2021-12-31
TWI781935B (zh) 2022-11-01
NZ747414A (en) 2025-06-27
RU2743170C2 (ru) 2021-02-15
CA3025847A1 (en) 2017-12-07
MX394560B (es) 2025-03-24
KR20190015252A (ko) 2019-02-13
ES2898771T3 (es) 2022-03-08
US20220204474A1 (en) 2022-06-30
BR112018074927A2 (pt) 2019-03-12
DOP2018000262A (es) 2019-02-28
AU2017272505A8 (en) 2018-11-29
IL263132A (en) 2018-12-31
PT3464266T (pt) 2021-11-23
MY199070A (en) 2023-10-12
US20200216413A1 (en) 2020-07-09
KR102547834B1 (ko) 2023-06-26
AU2017272505B2 (en) 2021-10-07
CO2018013029A2 (es) 2018-12-28
IL263132B (en) 2022-04-01
CN109219603B (zh) 2025-06-27
RU2018145860A (ru) 2020-07-09

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