DK3487996T5 - Serinproteasevarianter og polynukleotider, der koder for samme - Google Patents
Serinproteasevarianter og polynukleotider, der koder for samme Download PDFInfo
- Publication number
- DK3487996T5 DK3487996T5 DK17746005.2T DK17746005T DK3487996T5 DK 3487996 T5 DK3487996 T5 DK 3487996T5 DK 17746005 T DK17746005 T DK 17746005T DK 3487996 T5 DK3487996 T5 DK 3487996T5
- Authority
- DK
- Denmark
- Prior art keywords
- polynucleotides encoding
- serine protease
- encoding same
- protease variants
- variants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Confectionery (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16180497 | 2016-07-21 | ||
| EP16195078 | 2016-10-21 | ||
| PCT/EP2017/067883 WO2018015304A1 (en) | 2016-07-21 | 2017-07-14 | Serine protease variants and polynucleotides encoding same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3487996T3 DK3487996T3 (da) | 2024-05-21 |
| DK3487996T5 true DK3487996T5 (da) | 2024-09-02 |
Family
ID=59501396
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17746005.2T DK3487996T5 (da) | 2016-07-21 | 2017-07-14 | Serinproteasevarianter og polynukleotider, der koder for samme |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US10927361B2 (da) |
| EP (1) | EP3487996B1 (da) |
| CN (1) | CN109642225A (da) |
| CA (1) | CA3028875A1 (da) |
| DK (1) | DK3487996T5 (da) |
| ES (1) | ES2981748T3 (da) |
| FI (1) | FI3487996T3 (da) |
| MX (1) | MX2019000805A (da) |
| WO (1) | WO2018015304A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3028875A1 (en) * | 2016-07-21 | 2018-01-25 | Novozymes A/S | Serine protease variants and polynucleotides encoding same |
| MX2019000743A (es) | 2016-07-21 | 2019-05-20 | Novozymes As | Variantes de serinproteasa y polinucleotidos que las codifican. |
| MX2021011166A (es) * | 2019-03-18 | 2021-10-22 | Novozymes As | Polipeptidos que tienen actividad pululanasa adecuados para usarse en licuefaccion. |
| KR102316445B1 (ko) * | 2019-11-29 | 2021-10-26 | 씨제이제일제당 주식회사 | 신규 세린 프로테아제 변이체 |
| CN112574978B (zh) * | 2021-01-19 | 2021-08-17 | 青岛尚德生物技术有限公司 | 提高降解醇溶蛋白能力的蛋白酶突变体及其编码基因和应用 |
| KR102613549B1 (ko) | 2021-03-12 | 2023-12-13 | 씨제이제일제당 주식회사 | 신규 세린 프로테아제 변이체 |
| CN119630280A (zh) | 2022-05-14 | 2025-03-14 | 诺维信公司 | 用于预防、处理、抑制和/或消除植物病原性侵染和感染的组合物和方法 |
| WO2024137252A1 (en) | 2022-12-19 | 2024-06-27 | Novozymes A/S | Process for reducing syrup viscosity in the backend of a process for producing a fermentation product |
| EP4638725A1 (en) | 2022-12-19 | 2025-10-29 | Novozymes A/S | Carbohydrate esterase family 3 (ce3) polypeptides having acetyl xylan esterase activity and polynucleotides encoding same |
| CN120693401A (zh) | 2022-12-19 | 2025-09-23 | 诺维信公司 | 包含阿拉伯呋喃糖苷酶和木聚糖酶的组合物及其用于增加半纤维素纤维溶解的用途 |
| CN120380140A (zh) | 2022-12-19 | 2025-07-25 | 诺维信公司 | 具有阿魏酸酯酶和/或乙酰木聚糖酯酶活性的碳水化合物酯酶家族1(ce1)多肽和编码其的多核苷酸 |
| EP4638768A2 (en) | 2022-12-19 | 2025-10-29 | Novozymes A/S | Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast |
| AU2024303961A1 (en) | 2023-06-13 | 2025-12-11 | Novozymes A/S | Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase |
| WO2025128568A1 (en) | 2023-12-11 | 2025-06-19 | Novozymes A/S | Composition and use thereof for increasing hemicellulosic fiber solubilization |
| WO2026008449A2 (en) | 2024-07-04 | 2026-01-08 | Novozymes A/S | A process for producing a fermentation product and a concentrated protein co-product |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3912590A (en) | 1973-01-03 | 1975-10-14 | Novo Industri As | Procedure for liquefying starch |
| US4316956A (en) | 1980-02-06 | 1982-02-23 | Novo Industri A/S | Fermentation process |
| US4335208A (en) | 1980-03-11 | 1982-06-15 | Novo Industri A/S | Saccharification of starch hydrolysates |
| JPS57174089A (en) | 1981-04-20 | 1982-10-26 | Novo Industri As | Chain dividing enzyme product |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| ES2052565T3 (es) | 1986-07-09 | 1994-07-16 | Novo Nordisk As | Un procedimiento para licuar una suspension de almidon o granos amilaceos. |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| JP3016587B2 (ja) | 1989-12-04 | 2000-03-06 | ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク | 非ステロイド抗炎症剤及びテトラサイクリンの配合 |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| US5231017A (en) | 1991-05-17 | 1993-07-27 | Solvay Enzymes, Inc. | Process for producing ethanol |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| WO1995033836A1 (en) | 1994-06-03 | 1995-12-14 | Novo Nordisk Biotech, Inc. | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
| ATE294871T1 (de) | 1994-06-30 | 2005-05-15 | Novozymes Biotech Inc | Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren |
| AR017331A1 (es) | 1997-10-13 | 2001-09-05 | Novozymes As | Polipeptidos mutantes de alfa-amilasas, aditivo para detergentes y composiciones detergentes que los comprenden. |
| DK1124949T3 (da) | 1998-10-26 | 2006-11-06 | Novozymes As | Konstruktion og screening af et DNA-bibliotek af interesse i trådformede svampeceller |
| CN100482801C (zh) | 1999-03-22 | 2009-04-29 | 诺沃奇梅兹有限公司 | 用于在真菌细胞中表达基因的启动子 |
| EP1421187B1 (en) | 2001-07-27 | 2007-10-10 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Systems for in vivo site-directed mutagenesis using oligonucleotides |
| ES2319757T5 (es) | 2002-01-23 | 2018-05-22 | Dsm Ip Assets B.V. | Fermentación de azúcares de pentosa |
| US20030180900A1 (en) | 2002-02-08 | 2003-09-25 | Oreste Lantero | Methods for producing ethanol from carbon substrates |
| WO2004085627A1 (en) | 2003-03-26 | 2004-10-07 | Forskarpatent I Syd Ab | New saccharomyces cerevisiae strains utilizing xylose |
| US7968318B2 (en) | 2006-06-06 | 2011-06-28 | Genencor International, Inc. | Process for conversion of granular starch to ethanol |
| JP5625199B2 (ja) | 2008-03-07 | 2014-11-19 | ディーエスエム アイピー アセッツ ビー.ブイ. | ペントース糖発酵細胞 |
| EP2326723B1 (en) * | 2008-08-20 | 2016-07-06 | Novozymes A/S | Processes for producing fermentation products |
| US9334488B2 (en) | 2008-12-24 | 2016-05-10 | Dsm Ip Assets B.V. | Xylose isomerase genes and their use in fermentation of pentose sugars |
| MX2012006096A (es) | 2009-11-30 | 2012-07-03 | Novozymes North America Inc | Polipeptidos que tienen actividad glucoamilasa y polinucleotidos que codifican para los mismos. |
| ES2534067T3 (es) | 2009-12-01 | 2015-04-17 | Novozymes A/S | Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos |
| CN102753680B (zh) | 2009-12-11 | 2015-05-13 | 诺维信公司 | 蛋白酶变体 |
| EP2636993A4 (en) | 2010-11-05 | 2016-01-20 | Panasonic Ip Man Co Ltd | STEREOSCOPIC IMAGE PROCESSING DEVICE AND STEREOSCOPIC IMAGE PROCESSING METHOD |
| CN103298932B (zh) | 2010-11-08 | 2016-08-10 | 诺维信公司 | 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸 |
| EP2527448A1 (en) | 2011-05-23 | 2012-11-28 | Novozymes A/S | Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi |
| BR112014000143B1 (pt) | 2011-07-06 | 2021-04-06 | Novozymes A/S | Variante de alfa-amilase, polinucleotídeo isolado, vetor de expressão, célula hospedeira, métodos de produzir uma variante de alfa-amilase, para produzir um produto de fermentação a partir de um material contendo amido, e, para a produção um derivado de amido enzimaticamente modificado |
| DK2893012T3 (da) | 2012-09-05 | 2018-12-03 | Novozymes As | Polypeptider med proteaseaktivitet |
| BR112016003339B1 (pt) * | 2013-08-30 | 2023-02-14 | Novozymes A/S | Composição de enzima, e, processo de produção de um produto de fermentação a partir de material contendo amido |
| ES2810198T3 (es) | 2014-06-27 | 2021-03-08 | Dsm Ip Assets Bv | Método para mejorar el valor nutricional del pienso para animales |
| CN108350444A (zh) | 2015-09-25 | 2018-07-31 | 诺维信公司 | 丝氨酸蛋白酶用于改进乙醇产量的用途 |
| CA3028875A1 (en) * | 2016-07-21 | 2018-01-25 | Novozymes A/S | Serine protease variants and polynucleotides encoding same |
| MX2019000743A (es) * | 2016-07-21 | 2019-05-20 | Novozymes As | Variantes de serinproteasa y polinucleotidos que las codifican. |
-
2017
- 2017-07-14 CA CA3028875A patent/CA3028875A1/en active Pending
- 2017-07-14 DK DK17746005.2T patent/DK3487996T5/da active
- 2017-07-14 MX MX2019000805A patent/MX2019000805A/es unknown
- 2017-07-14 CN CN201780044163.1A patent/CN109642225A/zh active Pending
- 2017-07-14 ES ES17746005T patent/ES2981748T3/es active Active
- 2017-07-14 WO PCT/EP2017/067883 patent/WO2018015304A1/en not_active Ceased
- 2017-07-14 FI FIEP17746005.2T patent/FI3487996T3/fi active
- 2017-07-14 EP EP17746005.2A patent/EP3487996B1/en active Active
- 2017-07-14 US US16/318,496 patent/US10927361B2/en active Active
-
2021
- 2021-01-14 US US17/148,790 patent/US11447763B2/en active Active
- 2021-12-09 US US17/547,098 patent/US12291730B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US12291730B2 (en) | 2025-05-06 |
| US20220090041A1 (en) | 2022-03-24 |
| US10927361B2 (en) | 2021-02-23 |
| DK3487996T3 (da) | 2024-05-21 |
| EP3487996A1 (en) | 2019-05-29 |
| EP3487996B1 (en) | 2024-04-10 |
| FI3487996T3 (fi) | 2024-07-10 |
| WO2018015304A1 (en) | 2018-01-25 |
| CN109642225A (zh) | 2019-04-16 |
| US11447763B2 (en) | 2022-09-20 |
| ES2981748T3 (es) | 2024-10-10 |
| CA3028875A1 (en) | 2018-01-25 |
| US20210139876A1 (en) | 2021-05-13 |
| MX2019000805A (es) | 2019-06-20 |
| US20190352629A1 (en) | 2019-11-21 |
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