DK350188A - Hidtil ukendte kolonistimulerende faktor-1-former - Google Patents

Hidtil ukendte kolonistimulerende faktor-1-former

Info

Publication number
DK350188A
DK350188A DK350188A DK350188A DK350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A DK 350188 A DK350188 A DK 350188A
Authority
DK
Denmark
Prior art keywords
forms
stimulating factor
colony stimulating
unknown
csf
Prior art date
Application number
DK350188A
Other languages
English (en)
Other versions
DK174237B1 (da
DK350188D0 (da
Inventor
Kirston Edward Koths
Mazie Yee Coyne
Robert Forgan Halenbeck
Janelle Nobel Van Arsdell
Ernest Seigo Kawasaki
George Arthur Martin
Martha Ballie Ladner
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DK350188D0 publication Critical patent/DK350188D0/da
Publication of DK350188A publication Critical patent/DK350188A/da
Application granted granted Critical
Publication of DK174237B1 publication Critical patent/DK174237B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Luminescent Compositions (AREA)
DK198803501A 1986-10-24 1988-06-24 DNA-sekvenser, der koder for N2- eller N3-trunkerede former af den lange form og den korte form af CSF-1 og anvendelse heraf i vektorer, ekspressionssystemer, rekombinante værtsceller, samt en fremgangsmåde til fremstilling...... DK174237B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US92306786A 1986-10-24 1986-10-24
US92306786 1986-10-24
US3965487A 1987-04-16 1987-04-16
US3965787A 1987-04-16 1987-04-16
US3965487 1987-04-16
US3965787 1987-04-16
PCT/US1987/002679 WO1988003173A2 (en) 1986-10-24 1987-10-16 New forms of colony stimulating factor-1
US8702679 1987-10-16

Publications (3)

Publication Number Publication Date
DK350188D0 DK350188D0 (da) 1988-06-24
DK350188A true DK350188A (da) 1988-08-19
DK174237B1 DK174237B1 (da) 2002-10-07

Family

ID=27365583

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198803501A DK174237B1 (da) 1986-10-24 1988-06-24 DNA-sekvenser, der koder for N2- eller N3-trunkerede former af den lange form og den korte form af CSF-1 og anvendelse heraf i vektorer, ekspressionssystemer, rekombinante værtsceller, samt en fremgangsmåde til fremstilling......

Country Status (12)

Country Link
EP (1) EP0272779B1 (da)
JP (1) JP2644794B2 (da)
AT (1) ATE105869T1 (da)
AU (2) AU8007087A (da)
CA (1) CA1339032C (da)
DE (1) DE3789859T2 (da)
DK (1) DK174237B1 (da)
ES (1) ES2052580T3 (da)
FI (1) FI102190B1 (da)
HU (1) HU215241B (da)
NO (1) NO301775B1 (da)
WO (1) WO1988003173A2 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117422A (en) * 1985-02-05 2000-09-12 Chiron Corporation N∇2-CSF-1(long form) and carboxy truncated fragments thereof
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs
MX9203130A (es) * 1986-05-06 1992-07-01 Genetics Inst Produccion de m-csf
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトm−csf
AU606099B2 (en) * 1986-12-07 1991-01-31 Japan Science And Technology Corporation Colony-stimulating factor and method for preparation thereof
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1317244C (en) * 1987-07-24 1993-05-04 Ernest Seigo Kawasaki Production of biologically active forms of csf using a baculovirus (acnpv)-insect cell expression system
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
EP0410751B1 (en) * 1989-07-27 1996-04-10 Denki Kagaku Kogyo Kabushiki Kaisha Gene encoding M-CSF and related recombinant systems thereof
WO1991006567A1 (fr) * 1989-11-07 1991-05-16 Otsuka Pharmaceutical Co., Ltd. Derive de m-csf, vecteur d'expression de ce derive, produit de transformation par ce vecteur, et production de ces composes
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
DE4014750A1 (de) * 1990-05-08 1991-11-14 Boehringer Mannheim Gmbh Muteine des granulozyten-stimulierenden faktors (g-csf)
AU639091B2 (en) * 1991-04-24 1993-07-15 Otsuka Pharmaceutical Co., Ltd. M-csf derivatives, expression vectors for said derivatives, transformants carrying said vectors and production of these
EP0668914B1 (en) 1992-06-09 2000-08-16 Chiron Corporation Crystallization of m-csf
AU6125294A (en) * 1993-01-13 1994-08-15 Genetics Institute Inc. Process for producing m-csf 223
GB2355791B (en) 1999-10-28 2004-10-20 Molecular Light Tech Res Ltd Detection of mRNA expression using chemiluminescent labelled probes
KR100371264B1 (ko) * 2000-01-25 2003-02-05 양문식 무라인 그래뉼로사이트-매크로파지 콜로니 자극 인자를포함하는 재조합 벡터와 그것을 발현하는 재조합아스퍼질러스 나이거
EP4502152A3 (en) 2009-10-06 2025-04-30 Regeneron Pharmaceuticals, Inc. Genetically modified mice and engraftment
SG10202008003VA (en) 2011-02-15 2020-10-29 Regeneron Pharma Humanized m-csf mice
FI2892330T3 (fi) 2012-09-07 2023-03-25 Univ Yale Geneettisesti muokattuja hiiriä ja menetelmiä niiden käyttämiseksi
MX377561B (es) 2012-11-05 2025-03-10 Regeneron Pharma Animales no humanos genéticamente modificados y métodos de uso de los mismos.
MX2016014995A (es) 2014-05-19 2017-03-31 Regeneron Pharma Animales no humanos geneticamente modificados que expresan eritropoyetina de humano.
ES2950399T3 (es) 2015-04-13 2023-10-09 Regeneron Pharma Ratones humanizados Sirpa-IL15 insertados y métodos de uso de los mismos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3689391T2 (de) * 1985-02-05 1994-06-30 Cetus Oncology Corp., Emeryville, Calif. Rekombinanter koloniestimulierender faktor-1.
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子

Also Published As

Publication number Publication date
DK174237B1 (da) 2002-10-07
FI102190B (fi) 1998-10-30
JP2644794B2 (ja) 1997-08-25
FI102190B1 (fi) 1998-10-30
CA1339032C (en) 1997-04-01
HUT47635A (en) 1989-03-28
DK350188D0 (da) 1988-06-24
HU215241B (hu) 1998-11-30
AU8007087A (en) 1988-04-28
ATE105869T1 (de) 1994-06-15
EP0272779B1 (en) 1994-05-18
WO1988003173A2 (en) 1988-05-05
AU8149491A (en) 1991-10-31
EP0272779A2 (en) 1988-06-29
AU646277B2 (en) 1994-02-17
ES2052580T3 (es) 1994-07-16
NO882772L (no) 1988-08-22
FI883056A0 (fi) 1988-06-23
WO1988003173A3 (en) 1988-07-28
FI883056L (fi) 1988-06-23
EP0272779A3 (en) 1988-08-03
NO882772D0 (no) 1988-06-22
NO301775B1 (no) 1997-12-08
JPH01501283A (ja) 1989-05-11
DE3789859T2 (de) 1994-09-15
DE3789859D1 (de) 1994-06-23

Similar Documents

Publication Publication Date Title
DK350188A (da) Hidtil ukendte kolonistimulerende faktor-1-former
ATE124959T1 (de) Herstellung und verwendung von nicht- glycosiliertem il-6.
DE68929551D1 (de) Menschliche DNase
DZ467A1 (fr) Interferon immunitaire urbain.
DE3750113D1 (de) Für menschliche "Colony-stimulating"-Faktoren kodierendes Gen.
ATE127841T1 (de) Hirudinderivate.
ATE147099T1 (de) Menschliches gp130-protein codierende dns
NO872988D0 (no) Pattedyr-interleukin-4.
BG49941A3 (bg) Метод за получаване на рекомбинантен колонии стимулиращ фактор-1
DE3584579D1 (de) Herstellung von polypeptiden mit human-gammainterferon-aktivitaet.
EP0383837A4 (en) Alveolar surfactant proteins
BG49827A3 (bg) Метод за получаване на пречистен биологично активен рекомбинантен човешки колоний стимулиращ фактор
NO177863C (no) Fremgangsmåte for fremstilling av rekombinant humant IFN-type I, IFN1, IFN-pseudo-2, -3, og -4, samt ekspresjonsvektorer
DK12990D0 (da) Human granulocyt-makrofag-kolonistimulerende faktor og muteiner heraf
ATE190497T1 (de) Verwendung des rekombinanten koloniestimulierenden faktors-1
ATE127842T1 (de) Megakaryocytopoietin, seine herstellung und benutzung.
ATE100143T1 (de) Hormone und verfahren zur herstellung, verwendung und pruefung derselben.
ES8703928A1 (es) Un metodo para preparar la proteina factor de estimulacion de colonias (csf-1)recombinante

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK