ATE105869T1 - Formen des koloniestimulierungsfaktors 1. - Google Patents

Formen des koloniestimulierungsfaktors 1.

Info

Publication number
ATE105869T1
ATE105869T1 AT87309409T AT87309409T ATE105869T1 AT E105869 T1 ATE105869 T1 AT E105869T1 AT 87309409 T AT87309409 T AT 87309409T AT 87309409 T AT87309409 T AT 87309409T AT E105869 T1 ATE105869 T1 AT E105869T1
Authority
AT
Austria
Prior art keywords
forms
stimulation factor
colony stimulation
csf
protein
Prior art date
Application number
AT87309409T
Other languages
English (en)
Inventor
Kirston Edward Koths
Robert Forgan Halenbeck
Ernest Seigo Kawasaki
Martha Ballie Ladner
Mazie Yee Coyne
Arsdell Janelle Nobel Van
George Arthur Martin
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Application granted granted Critical
Publication of ATE105869T1 publication Critical patent/ATE105869T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Liquid Crystal Substances (AREA)
  • Luminescent Compositions (AREA)
  • Pyrane Compounds (AREA)
AT87309409T 1986-10-24 1987-10-23 Formen des koloniestimulierungsfaktors 1. ATE105869T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92306786A 1986-10-24 1986-10-24
US3965487A 1987-04-16 1987-04-16
US3965787A 1987-04-16 1987-04-16

Publications (1)

Publication Number Publication Date
ATE105869T1 true ATE105869T1 (de) 1994-06-15

Family

ID=27365583

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87309409T ATE105869T1 (de) 1986-10-24 1987-10-23 Formen des koloniestimulierungsfaktors 1.

Country Status (12)

Country Link
EP (1) EP0272779B1 (de)
JP (1) JP2644794B2 (de)
AT (1) ATE105869T1 (de)
AU (2) AU8007087A (de)
CA (1) CA1339032C (de)
DE (1) DE3789859T2 (de)
DK (1) DK174237B1 (de)
ES (1) ES2052580T3 (de)
FI (1) FI102190B1 (de)
HU (1) HU215241B (de)
NO (1) NO301775B1 (de)
WO (1) WO1988003173A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117422A (en) * 1985-02-05 2000-09-12 Chiron Corporation N∇2-CSF-1(long form) and carboxy truncated fragments thereof
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
AU595864B2 (en) * 1986-03-14 1990-04-12 Otsuka Pharmaceutical Co., Ltd. Il-1 alpha derivatives and drugs
HU212277B (en) * 1986-05-06 1996-04-29 Genetics Inst Process for producing m-csf
JP2583829B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 ヒトｍ−ｃｓｆ
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
DE3777623D1 (de) * 1986-12-07 1992-04-23 Morinaga Milk Industry Co Ltd Kolonie-stimulierender faktor und verfahren zu seiner herstellung.
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
WO1989001038A1 (en) * 1987-07-24 1989-02-09 Cetus Corporation PRODUCTION OF BIOLOGICALLY ACTIVE FORMS OF CSF USING A BACULOVIRUS (AcNPV)-INSECT CELL EXPRESSION SYSTEM
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
JPH0610137B2 (ja) * 1988-02-29 1994-02-09 新技術事業団 ヒト単球−マクロファージコロニー刺激因子を有効成分とする造血器疾患治療剤
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
DE69026440T2 (de) * 1989-07-27 1996-10-17 Denki Kagaku Kogyo Kk Für M-CSF kodierendes Gen und dazu gehörende rekombinante Systeme
WO1991006567A1 (fr) * 1989-11-07 1991-05-16 Otsuka Pharmaceutical Co., Ltd. Derive de m-csf, vecteur d'expression de ce derive, produit de transformation par ce vecteur, et production de ces composes
US5714140A (en) * 1989-12-13 1998-02-03 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting the production of bioactive IL-1 by administering M-CSF
DE4014750A1 (de) * 1990-05-08 1991-11-14 Boehringer Mannheim Gmbh Muteine des granulozyten-stimulierenden faktors (g-csf)
AU639091B2 (en) * 1991-04-24 1993-07-15 Otsuka Pharmaceutical Co., Ltd. M-csf derivatives, expression vectors for said derivatives, transformants carrying said vectors and production of these
US5866114A (en) * 1992-06-09 1999-02-02 Chiron Corporation Crystallization of M-CSFα
JPH08505534A (ja) * 1993-01-13 1996-06-18 森永乳業株式会社 Ｍ−ｃｓｆ２２３の製造方法
GB2355791B (en) 1999-10-28 2004-10-20 Molecular Light Tech Res Ltd Detection of mRNA expression using chemiluminescent labelled probes
KR100371264B1 (ko) * 2000-01-25 2003-02-05 양문식 무라인 그래뉼로사이트-매크로파지 콜로니 자극 인자를포함하는 재조합 벡터와 그것을 발현하는 재조합아스퍼질러스 나이거
US8541646B2 (en) 2009-10-06 2013-09-24 Regeneron Pharmaceuticals, Inc. Genetically modified mice and engraftment
PT4233537T (pt) 2011-02-15 2025-09-08 Regeneron Pharma Ratinhos humanizados para m-csf e utilizações dos mesmos
IN2015DN02032A (de) 2012-09-07 2015-08-14 Univ Yale
ES2884598T3 (es) 2012-11-05 2021-12-10 Regeneron Pharma Animales no humanos modificados genéticamente y métodos de uso de los mismos
PT3482629T (pt) 2014-05-19 2021-02-18 Univ Yale Animais não humanos geneticamente modificados que expressam epo humana
PT3282835T (pt) 2015-04-13 2023-07-25 Univ Yale Ratinhos knockin de sirpa-il15 humanizadas e métodos de utilização dos mesmos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594045B2 (en) * 1985-02-05 1990-03-01 Chiron Corporation Recombinant colony stimulating factor-1
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子

Also Published As

Publication number Publication date
DK350188D0 (da) 1988-06-24
AU8007087A (en) 1988-04-28
NO882772D0 (no) 1988-06-22
WO1988003173A3 (en) 1988-07-28
HUT47635A (en) 1989-03-28
DK174237B1 (da) 2002-10-07
DK350188A (da) 1988-08-19
EP0272779A3 (en) 1988-08-03
WO1988003173A2 (en) 1988-05-05
FI883056A0 (fi) 1988-06-23
DE3789859T2 (de) 1994-09-15
AU646277B2 (en) 1994-02-17
EP0272779B1 (de) 1994-05-18
NO882772L (no) 1988-08-22
FI883056L (fi) 1988-06-23
ES2052580T3 (es) 1994-07-16
FI102190B (fi) 1998-10-30
EP0272779A2 (de) 1988-06-29
DE3789859D1 (de) 1994-06-23
AU8149491A (en) 1991-10-31
CA1339032C (en) 1997-04-01
FI102190B1 (fi) 1998-10-30
JP2644794B2 (ja) 1997-08-25
HU215241B (hu) 1998-11-30
NO301775B1 (no) 1997-12-08
JPH01501283A (ja) 1989-05-11

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee