DK3545080T3 - Cellulært mikrokompartment og fremstillingsfremgangsmåder - Google Patents

Cellulært mikrokompartment og fremstillingsfremgangsmåder Download PDF

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Publication number
DK3545080T3
DK3545080T3 DK17816914.0T DK17816914T DK3545080T3 DK 3545080 T3 DK3545080 T3 DK 3545080T3 DK 17816914 T DK17816914 T DK 17816914T DK 3545080 T3 DK3545080 T3 DK 3545080T3
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DK
Denmark
Prior art keywords
manufacturing methods
cellular microcompartment
microcompartment
cellular
manufacturing
Prior art date
Application number
DK17816914.0T
Other languages
English (en)
Inventor
Maxime Feyeux
Kevin Alessandri
Pierre Nassoy
Laurent Cognet
Erwan Bezard
Gaelle Recher
Original Assignee
Univ Bordeaux
Centre Nat Rech Scient
Inst Doptique Theorique Et Appliquee
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Application filed by Univ Bordeaux, Centre Nat Rech Scient, Inst Doptique Theorique Et Appliquee filed Critical Univ Bordeaux
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Publication of DK3545080T3 publication Critical patent/DK3545080T3/da

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/01—Drops
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C12N5/0075—General culture methods using substrates using microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/74—Alginate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Sustainable Development (AREA)
  • Transplantation (AREA)
  • Developmental Biology & Embryology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK17816914.0T 2016-11-23 2017-11-23 Cellulært mikrokompartment og fremstillingsfremgangsmåder DK3545080T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1661377A FR3059009B1 (fr) 2016-11-23 2016-11-23 Microcompartiment cellulaire et procedes de preparation
PCT/FR2017/053225 WO2018096277A1 (fr) 2016-11-23 2017-11-23 Microcompartiment cellulaire et procédés de préparation

Publications (1)

Publication Number Publication Date
DK3545080T3 true DK3545080T3 (da) 2025-02-10

Family

ID=58992916

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17816914.0T DK3545080T3 (da) 2016-11-23 2017-11-23 Cellulært mikrokompartment og fremstillingsfremgangsmåder

Country Status (15)

Country Link
US (4) US11807870B2 (da)
EP (3) EP4223870A1 (da)
JP (3) JP7154525B2 (da)
KR (3) KR102671098B1 (da)
CN (1) CN110603319A (da)
AU (2) AU2017365846B2 (da)
BR (1) BR112019010512A2 (da)
CL (1) CL2019001378A1 (da)
DK (1) DK3545080T3 (da)
ES (1) ES3013874T3 (da)
FR (1) FR3059009B1 (da)
IL (1) IL266777B2 (da)
MX (2) MX2019006050A (da)
PL (1) PL3545080T3 (da)
WO (1) WO2018096277A1 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3058892B1 (fr) 2016-11-23 2021-04-09 Univ Bordeaux Unite de tissu neural et utilisation d'une telle unite pour l'implantation dans le systeme nerveux d'un mammifere
FR3059009B1 (fr) 2016-11-23 2018-12-07 Universite de Bordeaux Microcompartiment cellulaire et procedes de preparation
US20220183271A1 (en) * 2019-03-13 2022-06-16 Membrane Protective Technologies, Inc. Methods and Systems for Protective Supplementation During Temperature Depression
FR3098223A1 (fr) 2019-07-05 2021-01-08 Universite de Bordeaux Procede de production in vitro de neurones de mammiferes
FR3099882A1 (fr) * 2019-08-12 2021-02-19 Treefrog Therapeutics Unité tridimensionnelle creuse de tissu rétinien et utilisation dans le traitement des rétinopathies
FR3108623B1 (fr) * 2020-03-27 2025-05-23 Treefrog Therapeutics Procédé de caractérisation d’un micro-tissu biologique par imagerie
FR3114322A1 (fr) 2020-09-21 2022-03-25 Treefrog Therapeutics Tissu cardiaque particulier et utilisation dans le traitement de pathologies cardiaque
FR3114321A1 (fr) * 2020-09-21 2022-03-25 Treefrog Therapeutics Microcompartiments cellulaires comprenant des cellules humaines en cours de différenciation cardiaque, tissus obtenus à partir de ces microcompartiments et utilisations
FR3122883A1 (fr) * 2021-05-11 2022-11-18 Treefrog Therapeutics Microcompartiments cellulaires comprenant des cellules dont l’intégrité génomique est maintenue après amplification et procédé de préparation
JP2024521447A (ja) * 2021-06-16 2024-05-31 ツリーフロッグ テラピューティクス 複数の嚢胞を含む大型細胞微小区画
FR3124193B3 (fr) * 2021-06-16 2023-09-22 Treefrog Therapeutics Microcompartiments cellulaires de grande taille comprenant plusieurs cystes
JP2025520113A (ja) 2022-06-03 2025-07-01 フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー 組成物及び方法
FR3138661A1 (fr) 2022-08-08 2024-02-09 Treefrog Therapeutics Substitut de matrice extracellulaire dans un microcompartiment cellulaire
AU2023322418A1 (en) 2022-08-08 2025-02-13 Treefrog Therapeutics Extracellular matrix substitute in a cellular microcompartment
FR3141945A1 (fr) 2022-11-15 2024-05-17 Treefrog Therapeutics Substitut de matrice extracellulaire dans un microcompartiment cellulaire
CN121013907A (zh) * 2023-04-28 2025-11-25 株式会社细胞纤维 细胞胶囊、细胞群、细胞产物、细胞制剂及细胞群的制造方法
FR3151044B1 (fr) * 2023-07-11 2026-04-24 Treefrog Therapeutics Transduction et/ou transfection dans un microcompartiment en trois dimensions
FR3151338A1 (fr) 2023-07-18 2025-01-24 Treefrog Therapeutics Système d’encapsulation de cellules dans des compartiments de culture en trois dimensions
FR3151340A1 (fr) 2023-07-21 2025-01-24 Treefrog Therapeutics Différenciation neurale à partir de cellules pluripotentes
FR3158739A1 (fr) * 2024-01-25 2025-08-01 Treefrog Therapeutics Système d’encapsulation de cellules comportant une cuve de collecte
FR3158738A1 (fr) 2024-01-25 2025-08-01 Treefrog Therapeutics Système de production d’objets dans une solution avec un changement de milieu
FR3165017A1 (fr) 2024-07-24 2026-01-30 Treefrog Therapeutics Système d’encapsulation de cellules comportant un système de déplacement de solution à gaz sous pression
FR3167450A1 (fr) 2024-10-15 2026-04-17 Treefrog Therapeutics Système d’analyse de microcompartiments cellulaires ou de tissus cellulaires
WO2026139294A1 (fr) 2024-12-23 2026-07-02 Treefrog Therapeutics Système d'encapsulation de cellules comportant des distributeurs de solution
FR3170504A1 (fr) 2024-12-23 2026-06-26 Treefrog Therapeutics Système d’encapsulation de cellules comportant des distributeurs de solution
FR3170505A1 (fr) 2024-12-23 2026-06-26 Treefrog Therapeutics Système d’encapsulation de cellules comportant une cuve de collecte

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG174471A1 (en) * 2009-03-20 2011-10-28 Agency Science Tech & Res Culture of pluripotent and multipotent cells on microcarriers
WO2010105311A1 (en) * 2009-03-20 2010-09-23 Angioblast Systems, Inc. Production of reprogrammed pluripotent cells
JP5365863B2 (ja) * 2009-08-21 2013-12-11 株式会社リコー トナーの製造装置及びトナーの製造方法
WO2011046105A1 (ja) * 2009-10-14 2011-04-21 国立大学法人 東京大学 被覆されたマイクロゲルファイバ
FR2986165B1 (fr) * 2012-01-31 2015-07-24 Capsum Procede de preparation de capsules rigidifiees
US20140127290A1 (en) * 2012-11-08 2014-05-08 Ohio State Innovation Foundation Microcapsules Encapsulating Living Cells
US10544036B2 (en) * 2013-04-30 2020-01-28 The Governing Council Of The University Of Toronto Microfluidic devices and methods for the extrusion of tubular structures
US9587221B2 (en) * 2013-11-11 2017-03-07 Auburn University Encapsulation and cardiac differentiation of hiPSCs in 3D PEG-fibrinogen hydrogels
WO2015178427A1 (ja) 2014-05-20 2015-11-26 国立大学法人 東京大学 中空マイクロファイバ
AU2016226178B2 (en) * 2015-03-03 2021-07-29 President And Fellows Of Harvard College Methods of generating functional human tissue
WO2016182022A1 (ja) 2015-05-14 2016-11-17 公立大学法人横浜市立大学 高分子を細胞と共に凝集させる技術
FR3059009B1 (fr) 2016-11-23 2018-12-07 Universite de Bordeaux Microcompartiment cellulaire et procedes de preparation
FR3058892B1 (fr) 2016-11-23 2021-04-09 Univ Bordeaux Unite de tissu neural et utilisation d'une telle unite pour l'implantation dans le systeme nerveux d'un mammifere

Also Published As

Publication number Publication date
FR3059009A1 (fr) 2018-05-25
EP3545080B1 (fr) 2024-11-13
WO2018096277A1 (fr) 2018-05-31
IL266777A (en) 2019-07-31
AU2024203214A1 (en) 2024-05-30
AU2017365846A1 (en) 2019-05-16
JP7154525B2 (ja) 2022-10-18
CL2019001378A1 (es) 2020-01-10
US20190330589A1 (en) 2019-10-31
KR102671098B1 (ko) 2024-05-30
EP4464776A2 (fr) 2024-11-20
US20240018469A1 (en) 2024-01-18
US11807870B2 (en) 2023-11-07
AU2017365846B2 (en) 2024-03-28
KR20240091112A (ko) 2024-06-21
US20250059504A1 (en) 2025-02-20
JP2024150583A (ja) 2024-10-23
JP2022166041A (ja) 2022-11-01
PL3545080T3 (pl) 2025-04-14
US12146153B2 (en) 2024-11-19
US20230117999A1 (en) 2023-04-20
CA3040781A1 (fr) 2018-05-31
MX2023008382A (es) 2023-07-31
KR20190111013A (ko) 2019-10-01
FR3059009B1 (fr) 2018-12-07
EP4464776A3 (fr) 2025-02-26
EP4223870A1 (fr) 2023-08-09
ES3013874T3 (en) 2025-04-15
IL266777B1 (en) 2024-05-01
KR20230169414A (ko) 2023-12-15
MX2019006050A (es) 2019-12-09
JP2019535326A (ja) 2019-12-12
IL266777B2 (en) 2024-09-01
BR112019010512A2 (pt) 2019-09-17
EP3545080A1 (fr) 2019-10-02
CN110603319A (zh) 2019-12-20

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