DK359487A - Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle - Google Patents

Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle

Info

Publication number
DK359487A
DK359487A DK359487A DK359487A DK359487A DK 359487 A DK359487 A DK 359487A DK 359487 A DK359487 A DK 359487A DK 359487 A DK359487 A DK 359487A DK 359487 A DK359487 A DK 359487A
Authority
DK
Denmark
Prior art keywords
host cell
factor viii
procedure
recombinant factor
increased expression
Prior art date
Application number
DK359487A
Other languages
English (en)
Other versions
DK359487D0 (da
Inventor
Sham Yuen Chan
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25384571&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK359487(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Miles Lab filed Critical Miles Lab
Publication of DK359487D0 publication Critical patent/DK359487D0/da
Publication of DK359487A publication Critical patent/DK359487A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK359487A 1986-07-11 1987-07-10 Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle DK359487A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88441286A 1986-07-11 1986-07-11

Publications (2)

Publication Number Publication Date
DK359487D0 DK359487D0 (da) 1987-07-10
DK359487A true DK359487A (da) 1988-01-12

Family

ID=25384571

Family Applications (1)

Application Number Title Priority Date Filing Date
DK359487A DK359487A (da) 1986-07-11 1987-07-10 Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle

Country Status (5)

Country Link
EP (1) EP0254076B1 (da)
JP (1) JPH0630610B2 (da)
AT (1) ATE63335T1 (da)
DE (1) DE3769872D1 (da)
DK (1) DK359487A (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE87663T1 (de) * 1986-01-03 1993-04-15 Genetics Inst Verfahren zur herstellung von faktor-viii:c-typ- proteinen.
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
US5595886A (en) 1986-01-27 1997-01-21 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
US6060447A (en) * 1987-05-19 2000-05-09 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
WO1991002065A1 (en) * 1989-08-11 1991-02-21 Zymogenetics, Inc. Cell culture methods for producing activated protein c
FR2657884B1 (fr) * 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
AU5462694A (en) * 1992-11-17 1994-06-08 Novo Nordisk A/S Improved recombinant production of proteins having factor viii:c activity
US5952198A (en) * 1995-05-04 1999-09-14 Bayer Corporation Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition
US6358703B1 (en) 1998-12-10 2002-03-19 Bayer Corporation Expression system for factor VIII
EP1707634A1 (en) 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
EP1739179A1 (en) 2005-06-30 2007-01-03 Octapharma AG Serum-free stable transfection and production of recombinant human proteins in human cell lines
EP1988101A1 (en) 2007-05-04 2008-11-05 Novo Nordisk A/S Improvement of factor VIII polypeptide titers in cell cultures
WO2011095604A1 (en) 2010-02-04 2011-08-11 Octapharma Biopharmaceuticals Gmbh Half-life prolongation of proteins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125409B (en) 1982-08-04 1985-11-13 Nat Res Dev Genetic engineering
JPH07106156B2 (ja) 1983-10-28 1995-11-15 ジェネティックス、インスティチュ−ト ファクタ−▲ｖｉｉｉ▼および関連生産物の製造
DE10399009I1 (de) 1984-01-12 2003-10-23 Chiron Corp F}r Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen
ZA852099B (en) 1984-03-26 1985-12-24 Meloy Lab Recombinant factor viii-c.
IL74909A (en) * 1984-04-20 1992-01-15 Genentech Inc Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
JPS6163283A (ja) * 1984-09-03 1986-04-01 Teijin Ltd ハイブリ−ド−マの培養方法

Also Published As

Publication number Publication date
DK359487D0 (da) 1987-07-10
EP0254076A1 (en) 1988-01-27
ATE63335T1 (de) 1991-05-15
JPS6342699A (ja) 1988-02-23
JPH0630610B2 (ja) 1994-04-27
DE3769872D1 (de) 1991-06-13
EP0254076B1 (en) 1991-05-08

Similar Documents

Publication Publication Date Title
DK359487D0 (da) Fremgangsmaade til udvirkning af foroeget ekspression af rekombinant faktor viii i en vaertscelle
DK306890D0 (da) Udtrykkelse af celleproliferation med decorin
ATE86663T1 (de) Glucoamylasegen.
DE3889665D1 (de) Serumfreie wachstumsmedien für insektenzellen und expression von produkten damit.
IL68366A (en) Process for expressing a gene encoding a protein comprising the enzymatic portion of human urokinase in a microorganism or cell culture
DE3485444D1 (de) Hybrid-dns-synthese von insulin.
GB8626878D0 (en) Dna
DE3784629D1 (de) Bioreaktor zum kultivieren von biologischem material.
JPS5639779A (en) Cell culturing method of hematisis a type virus
ATE124454T1 (de) Gentechnische herstellung von faktor xiiia.
DE68924251D1 (de) Gewinnung von thermostabilen Enzymen.
BR8406680A (pt) Processo para preparacao de um plasmidio,processo para expressao eficiente de proteinas heterologas,para preparacao de um transformante e processo para producao de prorrenina
ATE129287T1 (de) Bakterielles kollagenase-gen.
ATE60802T1 (de) Mikrobiologisches verfahren zur herstellung von menschlichem lysozym.
DE3783299D1 (de) Herstellung von mikroorganismen mit eiskristallbildungsaktivitaet.
DE3681398D1 (de) Verfahren zur herstellung von insulinaehnlichem wachstumsfaktor i (igf-i) und plasmid zu dessen herstellung.
ATE97958T1 (de) Zellenzuchtverfahren fuer die produktion von aktiviertem protein-c.
ATE96843T1 (de) Verfahren zur herstellung von mikrobieller cellulose.
DE3681629D1 (de) Cholesterolreiche fraktion, verfahren dafuer und verwendung derselben zur zellkultur.
ES542143A0 (es) Procedimiento para obtener un cultivo celular
DK378984A (da) Fremgangsmaade til fremstilling af arphamenin i hoejt udbytte
ATE92964T1 (de) Verfahren zur herstellung von itaconsaeure.
ATE178655T1 (de) Herstellungsprozess von fremdprotein
EP0169907A4 (en) METHOD OF PRODUCING POLYPEPTIDES WITH INGREDIENT OF SUGAR.
ATE49777T1 (de) Verfahren zur zuechtung von hepatozyten und cozuechtung von hepatozyten und von behandelten epithelien leberzellen.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment