DK3609908T3 - Lactaseenzymer med forbedrede egenskaber - Google Patents

Lactaseenzymer med forbedrede egenskaber

Info

Publication number
DK3609908T3
DK3609908T3 DK18715743.3T DK18715743T DK3609908T3 DK 3609908 T3 DK3609908 T3 DK 3609908T3 DK 18715743 T DK18715743 T DK 18715743T DK 3609908 T3 DK3609908 T3 DK 3609908T3
Authority
DK
Denmark
Prior art keywords
improved properties
lactase enzymes
lactase
enzymes
properties
Prior art date
Application number
DK18715743.3T
Other languages
English (en)
Inventor
Hans Raj
Pernille Smith
Thomas Eckhardt
Vojislav Vojinovic
Charlotte Elisabeth Grüner Schöller
Den Brink Johannes Maarten Van
Original Assignee
Kerry Group Services Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kerry Group Services Int Ltd filed Critical Kerry Group Services Int Ltd
Application granted granted Critical
Publication of DK3609908T3 publication Critical patent/DK3609908T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203—Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1206—Lactose hydrolysing enzymes, e.g. lactase, beta-galactosidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Dairy Products (AREA)
DK18715743.3T 2017-04-11 2018-04-11 Lactaseenzymer med forbedrede egenskaber DK3609908T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17166021 2017-04-11
EP17188670 2017-08-31
PCT/EP2018/059283 WO2018189238A1 (en) 2017-04-11 2018-04-11 Lactase enzymes with improved properties

Publications (1)

Publication Number Publication Date
DK3609908T3 true DK3609908T3 (da) 2025-11-17

Family

ID=61899317

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18715743.3T DK3609908T3 (da) 2017-04-11 2018-04-11 Lactaseenzymer med forbedrede egenskaber

Country Status (13)

Country Link
US (2) US12486305B2 (da)
EP (2) EP4682253A3 (da)
CN (1) CN110709411A (da)
AU (3) AU2018251967B2 (da)
BR (1) BR112019021115A2 (da)
CA (2) CA3059277A1 (da)
DK (1) DK3609908T3 (da)
ES (1) ES3057273T3 (da)
FI (1) FI3609908T3 (da)
HR (1) HRP20251309T1 (da)
MA (1) MA50219A (da)
PL (1) PL3609908T3 (da)
WO (1) WO2018189238A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR111462A1 (es) 2017-04-11 2019-07-17 Chr Hansen As Enzimas lactasa con actividad mejorada a bajas temperaturas
US12435326B2 (en) 2017-04-11 2025-10-07 Kerry Group Services International Ltd Lactase enzymes with improved properties
WO2018189242A1 (en) 2017-04-11 2018-10-18 Chr. Hansen A/S Lactase enzymes with improved activity at low temperatures
US12630811B2 (en) 2018-10-17 2026-05-19 Chr. Hansen A/S Lactase enzymes with improved properties at acidic PH
EP3930469A4 (en) * 2019-02-28 2023-03-01 DuPont Nutrition Biosciences ApS PROCESS FOR REDUCING LACTOSE AT HIGH TEMPERATURES
CN116528678A (zh) * 2020-11-12 2023-08-01 美丽生活有限责任公司 奶和其他乳制品中的连续乳糖水解
WO2023118436A1 (en) 2021-12-22 2023-06-29 Novozymes A/S Method of producing a milk-based product
EP4389886A1 (en) 2022-12-22 2024-06-26 Novozymes A/S Lactase enzymes and method of producing a milk-based product
WO2026099414A1 (en) 2024-11-08 2026-05-15 Novozymes A/S Method for producing gos syrup

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9101012D0 (en) 1991-01-17 1991-02-27 Univ Alberta Process for lactose hydrolysis in milk and other dairy products using sonicated dairy cultures
DK1261697T3 (da) 1999-07-09 2004-11-22 Univ Liege Kuldeaktiv beta-galactosidase, fremgangsmåde til fremstilling heraf og anvendelsen deraf
EP1227152A1 (en) 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Bacterial strain and genome of bifidobacterium
US7608700B2 (en) 2004-03-08 2009-10-27 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
US7459289B2 (en) 2004-03-08 2008-12-02 North Carolina State University Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor
RU2278160C2 (ru) 2004-04-13 2006-06-20 Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) РЕКОМБИНАНТНЫЙ БЕЛОК LACspCBD, ОБЛАДАЮЩИЙ БЕТА-ГАЛАКТОЗИДАЗНОЙ АКТИВНОСТЬЮ И СПОСОБНОСТЬЮ САМОПРОИЗВОЛЬНО СВЯЗЫВАТЬСЯ С ЦЕЛЛЮЛОЗОСОДЕРЖАЩИМИ СОРБЕНТАМИ, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК, КОДИРУЮЩАЯ СИНТЕЗ РЕКОМБИНАНТНОГО БЕЛКА LACspCBD, ШТАММ Escherichia coli M15 [pREP4, pLACspCBD] - ПРОДУЦЕНТ РЕКОМБИНАНТНОГО БЕЛКА LACspCBD, СПОСОБ ПОЛУЧЕНИЯ ИММОБИЛИЗОВАННОГО РЕКОМБИНАНТНОГО БЕЛКА LACspCBD НА ЦЕЛЛЮЛОЗЕ И СПОСОБ ФЕРМЕНТАТИВНОГО РАСЩЕПЛЕНИЯ ЛАКТОЗЫ
GB0601901D0 (en) * 2006-01-31 2006-03-08 Product and Process
GB0606112D0 (en) 2006-03-28 2006-05-03 Product and process
US8361756B2 (en) 2006-09-15 2013-01-29 The Regents Of The University Of California Bifidobacterial gene sequences and their use
EP2175714A4 (en) * 2007-07-10 2011-01-26 Monsanto Technology Llc TRANSGENIC PLANTS WITH IMPROVED AGRONOMIC CHARACTERISTICS
ES2591359T3 (es) 2007-12-03 2016-11-28 Novozymes A/S Método para producir un producto lácteo de bajo contenido en lactosa
US20090297660A1 (en) 2008-06-02 2009-12-03 Kraft Food Holdings, Inc. Cheese Products Containing Galacto-Oligosaccharides And Having Reduced Lactose Levels
EP2310532B1 (en) * 2008-06-30 2014-05-07 The Washington University Methods of promoting weight loss and associated arrays
DK2396403T3 (da) 2009-02-10 2016-01-11 Coldzymes Aps Kold-aktiv beta-galactosidase, fremgangsmåde til fremstilling heraf og anvendelse af et sådant enzym
EP2530148B1 (en) * 2011-05-30 2015-04-29 B.R.A.I.N. Biotechnology Research And Information Network AG Novel beta-galactosidases useful for the production of lactose depleted milk products
DK2841557T4 (da) 2012-04-25 2024-03-11 Chr Hansen As Anvendelse af mælkesyrebakterier til fremstilling af fermenterede fødevareprodukter med forøget naturlig sødme
CN103431042B (zh) * 2013-08-28 2015-01-21 光明乳业股份有限公司 发酵乳基料、脱乳清风味发酵乳、原料组合物及制备方法
ES2670422T3 (es) 2014-01-14 2018-05-30 Dsm Ip Assets B.V. Variantes enzimáticas mejoradas de lactasa de Kluyveromyces lactis
EP2957180B1 (en) 2014-06-19 2018-03-14 Chr. Hansen A/S Method of producing a fermented milk product with improved control of post acidification
WO2016060224A1 (ja) 2014-10-17 2016-04-21 合同酒精株式会社 ラクターゼ溶液及びそれを用いた乳
US11653659B2 (en) 2016-06-14 2023-05-23 Chr. Hansen A/S Fermented milk product with a reduced content of lactose
WO2018041869A1 (en) 2016-08-31 2018-03-08 Chr. Hansen A/S Process for producing a heat-treated fermented milk product
FI3821712T3 (fi) 2017-01-13 2023-01-13 Parannetulla menetelmällä saatu hapatettu maitotuote
DK3607097T3 (da) 2017-04-07 2023-09-18 Dupont Nutrition Biosci Aps Bacillus-værtsceller, der danner beta-galactosidaser og lactaser i fravær af p-nitrobenzylesterase-sideaktivitet
AR111462A1 (es) 2017-04-11 2019-07-17 Chr Hansen As Enzimas lactasa con actividad mejorada a bajas temperaturas
US12435326B2 (en) 2017-04-11 2025-10-07 Kerry Group Services International Ltd Lactase enzymes with improved properties
WO2018189242A1 (en) 2017-04-11 2018-10-18 Chr. Hansen A/S Lactase enzymes with improved activity at low temperatures
US12630811B2 (en) 2018-10-17 2026-05-19 Chr. Hansen A/S Lactase enzymes with improved properties at acidic PH

Also Published As

Publication number Publication date
BR112019021115A2 (pt) 2020-05-12
PL3609908T3 (pl) 2026-02-23
NZ757950A (en) 2025-09-26
AU2024204367A1 (en) 2024-07-18
US20260200993A1 (en) 2026-07-16
CN110709411A (zh) 2020-01-17
HRP20251309T1 (hr) 2026-02-13
EP4682253A2 (en) 2026-01-21
AU2022205242A1 (en) 2022-09-22
WO2018189238A1 (en) 2018-10-18
CA3309841A1 (en) 2026-06-21
MA50219A (fr) 2020-07-22
US12486305B2 (en) 2025-12-02
CA3059277A1 (en) 2018-10-18
RU2019134223A3 (da) 2021-05-14
FI3609908T3 (fi) 2025-11-24
ES3057273T3 (en) 2026-02-27
US20230076578A1 (en) 2023-03-09
EP4682253A3 (en) 2026-07-15
AU2018251967A1 (en) 2019-10-31
AU2024204367B2 (en) 2026-06-25
EP3609908B1 (en) 2025-10-15
EP3609908A1 (en) 2020-02-19
RU2019134223A (ru) 2021-05-11
AU2018251967B2 (en) 2022-04-14

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