DK3736341T5 - Fejlundertrykkelse i sekventerede dna-fragmenter under anvendelse af redundante læsninger med unikke molekylære indeks (umi'er) - Google Patents

Fejlundertrykkelse i sekventerede dna-fragmenter under anvendelse af redundante læsninger med unikke molekylære indeks (umi'er) Download PDF

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Publication number
DK3736341T5
DK3736341T5 DK20161152.2T DK20161152T DK3736341T5 DK 3736341 T5 DK3736341 T5 DK 3736341T5 DK 20161152 T DK20161152 T DK 20161152T DK 3736341 T5 DK3736341 T5 DK 3736341T5
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umis
dna fragments
unique molecular
sequenced dna
error suppression
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DK20161152.2T
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DK3736341T3 (da
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Sante Gnerre
Byoungsok Jung
Emrah Kostem
Alex Aravanis
Alex So
Xuyu Cai
Zhihong Zhang
Frank J Steemers
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Illumina Inc
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    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
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    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/191—Modifications characterised by incorporating an adaptor
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    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/119—Double strand sequencing
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    • C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
    • C12Q2535/122—Massive parallel sequencing
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    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
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    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/50—Detection characterised by immobilisation to a surface
    • C12Q2565/514—Detection characterised by immobilisation to a surface characterised by the use of the arrayed oligonucleotides as identifier tags, e.g. universal addressable array, anti-tag or tag complement array

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  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK20161152.2T 2015-04-28 2016-04-20 Fejlundertrykkelse i sekventerede dna-fragmenter under anvendelse af redundante læsninger med unikke molekylære indeks (umi'er) DK3736341T5 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562153699P 2015-04-28 2015-04-28
US201562193469P 2015-07-16 2015-07-16
US201562269485P 2015-12-18 2015-12-18
EP16720269.6A EP3289097B2 (en) 2015-04-28 2016-04-20 Error suppression in sequenced dna fragments using redundant reads with unique molecular indices (umis)

Publications (2)

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DK3736341T3 DK3736341T3 (da) 2023-09-18
DK3736341T5 true DK3736341T5 (da) 2024-08-26

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DK16720269.6T DK3289097T4 (da) 2015-04-28 2016-04-20 Fejlundertrykkelse i sekventerede dna-fragmenter under anvendelse af redundante aflæsninger med unikke molekylære indekser (umi'er)
DK20161152.2T DK3736341T5 (da) 2015-04-28 2016-04-20 Fejlundertrykkelse i sekventerede dna-fragmenter under anvendelse af redundante læsninger med unikke molekylære indeks (umi'er)

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US (3) US10844428B2 (da)
EP (4) EP4700778A2 (da)
JP (1) JP6685324B2 (da)
KR (1) KR102091312B1 (da)
CN (2) CN113832139A (da)
AU (3) AU2016256351B2 (da)
CA (2) CA3109403A1 (da)
DK (2) DK3289097T4 (da)
ES (3) ES2961338T3 (da)
FI (2) FI3736341T3 (da)
IL (3) IL285319B2 (da)
MX (3) MX2017013775A (da)
MY (1) MY181983A (da)
NZ (1) NZ736609A (da)
RU (1) RU2704286C2 (da)
SG (2) SG11201708859XA (da)
WO (1) WO2016176091A1 (da)
ZA (1) ZA201707231B (da)

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US20210108262A1 (en) 2021-04-15
CN108138227B (zh) 2021-09-17
RU2017137401A3 (da) 2019-05-28
IL285319B (en) 2022-10-01
DK3289097T4 (da) 2023-12-04
EP4266314A3 (en) 2024-01-24
DK3736341T3 (da) 2023-09-18
IL294600B2 (en) 2024-05-01
EP3289097B1 (en) 2020-03-18
ES3063683T3 (en) 2026-04-20
ES2799074T3 (es) 2020-12-14
MX2023004394A (es) 2023-05-04
KR102091312B1 (ko) 2020-03-19
EP4266314B1 (en) 2025-12-24
IL285319B2 (en) 2023-02-01
AU2016256351A1 (en) 2017-11-09
NZ736609A (en) 2020-06-26
MX2017013775A (es) 2018-08-15
JP2018514207A (ja) 2018-06-07
AU2016256351B2 (en) 2019-07-18
CA3109403A1 (en) 2016-11-03
US20240084376A1 (en) 2024-03-14
MY181983A (en) 2021-01-18
EP3736341B1 (en) 2023-08-23
BR112017024118A2 (pt) 2018-07-31
CN113832139A (zh) 2021-12-24
AU2022200179A1 (en) 2022-02-10
EP4266314C0 (en) 2025-12-24
CN108138227A (zh) 2018-06-08
SG10202006185QA (en) 2020-07-29
KR20180020137A (ko) 2018-02-27
EP4266314A2 (en) 2023-10-25
JP6685324B2 (ja) 2020-04-22
IL285319A (en) 2021-09-30
AU2019250200B2 (en) 2021-10-14
ZA201707231B (en) 2021-02-24
US20160319345A1 (en) 2016-11-03
WO2016176091A8 (en) 2017-12-21
US10844428B2 (en) 2020-11-24
MX2022008045A (es) 2022-07-27
EP3289097B2 (en) 2023-08-30
IL294600B1 (en) 2024-01-01
RU2017137401A (ru) 2019-05-28
AU2019250200A1 (en) 2019-11-07
US12577617B2 (en) 2026-03-17
ES2961338T3 (es) 2024-03-11
EP3736341A1 (en) 2020-11-11
CA2983935A1 (en) 2016-11-03
DK3289097T3 (da) 2020-06-02
CA2983935C (en) 2021-04-20

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