DK382786A - Overfladeaktivt rekombinant-alveolarprotein - Google Patents

Overfladeaktivt rekombinant-alveolarprotein Download PDF

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Publication number
DK382786A
DK382786A DK382786A DK382786A DK382786A DK 382786 A DK382786 A DK 382786A DK 382786 A DK382786 A DK 382786A DK 382786 A DK382786 A DK 382786A DK 382786 A DK382786 A DK 382786A
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DK
Denmark
Prior art keywords
surfactive
recombinant
asp
proteins
alveolar protein
Prior art date
Application number
DK382786A
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English (en)
Other versions
DK172227B1 (da
DK382786D0 (da
Inventor
Jr James W Schilling
Robert T White
Barbara Cordell
Bradley J Benzon
Original Assignee
California Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by California Biotechnology Inc filed Critical California Biotechnology Inc
Publication of DK382786D0 publication Critical patent/DK382786D0/da
Publication of DK382786A publication Critical patent/DK382786A/da
Application granted granted Critical
Publication of DK172227B1 publication Critical patent/DK172227B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK382786A 1984-12-11 1986-08-11 Overfladeaktivt pattedyr-alveolarprotein (pattedyr-ASP), rekombinant-DNA, der koder for et sådant ASP, overfladeaktivt lungeprotein, der kodes med et sådant DNA, rekombinant-ekspressionssystem, der indeholder et sådant DNA, rekombinant-værtscelle, der er transformeret med et sådant ekspressionssystem, fremgangsmåde til fremstilling af pattedyr-ASP'et under anvendelse af en sådan celle og ASP frems DK172227B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68035884 1984-12-11
US06/680,358 US4659805A (en) 1984-12-11 1984-12-11 Recombinant alveolar surfactant protein
US8502445 1985-12-10
PCT/US1985/002445 WO1986003408A1 (en) 1984-12-11 1985-12-10 Recombinant alveolar surfactant protein

Publications (3)

Publication Number Publication Date
DK382786D0 DK382786D0 (da) 1986-08-11
DK382786A true DK382786A (da) 1986-10-13
DK172227B1 DK172227B1 (da) 1998-01-12

Family

ID=24730771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK382786A DK172227B1 (da) 1984-12-11 1986-08-11 Overfladeaktivt pattedyr-alveolarprotein (pattedyr-ASP), rekombinant-DNA, der koder for et sådant ASP, overfladeaktivt lungeprotein, der kodes med et sådant DNA, rekombinant-ekspressionssystem, der indeholder et sådant DNA, rekombinant-værtscelle, der er transformeret med et sådant ekspressionssystem, fremgangsmåde til fremstilling af pattedyr-ASP'et under anvendelse af en sådan celle og ASP frems

Country Status (13)

Country Link
US (1) US4659805A (da)
EP (1) EP0210189B1 (da)
JP (3) JPH07108917B2 (da)
KR (1) KR900004798B1 (da)
AT (1) ATE115147T1 (da)
AU (1) AU585579B2 (da)
DE (2) DE3590648T1 (da)
DK (1) DK172227B1 (da)
ES (1) ES8801517A1 (da)
GB (1) GB2181138B (da)
IE (1) IE67067B1 (da)
NO (1) NO177678C (da)
WO (1) WO1986003408A1 (da)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
US5430020A (en) * 1984-12-11 1995-07-04 Scios Nova Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US5840527A (en) * 1984-12-11 1998-11-24 Byk Gulden Lomberg Chemische Fabrik Gmbh Recombinant alveolar surfactant protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
MX169643B (es) * 1985-04-12 1993-07-16 Oronzio De Nora Impianti Electrodo para procesos electroquimicos, procedimiento para su produccion y cuba de electrolisis conteniendo dicho electrodo
US4918161A (en) * 1985-09-26 1990-04-17 Genetics Institute, Inc. Low molecular weight pulmonary surfactant proteins
US5055553A (en) * 1985-09-26 1991-10-08 Genetics Institute Inc. Low molecular weight pulmonary surfactant proteins
US4882422A (en) * 1985-10-24 1989-11-21 Genetics Institute, Inc. Pulmonary surfactant proteins
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
EP0273916A4 (en) * 1986-05-06 1989-11-30 Childrens Hosp Medical Center LUNG HYDROPHOBES, PROTEIN ASSOCIATED TO A SURFACE ACTIVE MEDIUM OF 6000 DALTON MOLECULAR WEIGHT AND MULTIMEREOUS ITEMS.
EP0290516A4 (en) * 1986-10-24 1989-11-14 Jeffrey A Whitsett PROTEINS RELATED TO SURFACE-EFFECTIVE HYDROPHOBIC LUNG ACTIVE SUBSTANCES.
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
WO1988005820A1 (en) * 1987-01-29 1988-08-11 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5164369A (en) * 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US6613734B2 (en) 1988-01-06 2003-09-02 The Scripps Research Institute Peptides-containing liposomal surfactants
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
US5006343A (en) * 1988-12-29 1991-04-09 Benson Bradley J Pulmonary administration of pharmaceutically active substances
EP0458167B1 (en) * 1990-05-21 1997-04-23 Abbott Laboratories Fatty acid-pulmonary surfactant conjugates
GB9120005D0 (en) * 1991-09-19 1991-11-06 Wellcome Found Method of administering phospholipid dispersions
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
DK1173194T3 (da) * 1999-01-19 2004-10-18 Altana Pharma Ag Rekombinant SP-A til behandlingen eller forebyggelsen af lungeinfektion og -inflammation
US7053176B1 (en) 1999-09-16 2006-05-30 Altana Pharma Ag Combination of C1-INH and lung surfactant for the treatment of respiratory disorders
JP2001137349A (ja) 1999-11-16 2001-05-22 Asahi Optical Co Ltd 内視鏡用噴霧具
AU2001278864A1 (en) * 2000-06-30 2002-01-30 University Of Cincinnati Peptides with antioxidant and antimicrobial properties
ES2346048T3 (es) 2001-10-11 2010-10-08 Nycomed Gmbh Nueva utilizacion de un agente tensioactivo pulmonar.
SE0203591D0 (sv) 2002-12-04 2002-12-04 Siemens Elema Ab Förfarande för beredning av ett mediakament och en medicinsk anordning
CA2575513C (en) 2004-08-06 2014-09-16 Altana Pharma Ag Composition comprising a pulmonary surfactant and a tnf-derived peptide
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
SI1841458T1 (sl) 2005-01-06 2012-04-30 Discovery Lab Inc Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije
JP2010503731A (ja) 2006-09-19 2010-02-04 ディスカバリー ラボラトリーズ，インコーポレイテッド 肺サーファクタント製剤および粘液クリアランスの促進方法
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
WO2010068754A2 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4506013A (en) * 1980-10-03 1985-03-19 Eli Lilly And Company Stabilizing and selecting recombinant DNA host cells
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
US4562003A (en) * 1984-10-26 1985-12-31 California Biotechnology, Inc. Monoclonal antibodies against alveolar surfactant protein
ATE89314T1 (de) * 1985-02-13 1993-05-15 Scios Nova Inc Menschlicher metallothionein ii-promotor in saeugetierexpressionssystemen.

Also Published As

Publication number Publication date
DE3587958D1 (de) 1995-01-19
WO1986003408A1 (en) 1986-06-19
JPH08224091A (ja) 1996-09-03
KR900004798B1 (ko) 1990-07-06
EP0210189A4 (en) 1988-11-09
HK1005883A1 (en) 1999-01-29
GB2181138A (en) 1987-04-15
IE853133L (en) 1986-06-11
JPH07108917B2 (ja) 1995-11-22
NO863197D0 (no) 1986-08-07
DE3587958T2 (de) 1995-05-04
JPS62501122A (ja) 1987-05-07
NO177678C (no) 1995-11-01
GB2181138B (en) 1989-01-25
ES549817A0 (es) 1988-01-16
JP2500197B2 (ja) 1996-05-29
EP0210189B1 (en) 1994-12-07
ATE115147T1 (de) 1994-12-15
DE3590648T1 (da) 1987-02-19
US4659805A (en) 1987-04-21
EP0210189A1 (en) 1987-02-04
GB8619801D0 (en) 1986-09-24
IE67067B1 (en) 1996-02-21
AU585579B2 (en) 1989-06-22
NO863197L (no) 1986-08-07
KR870700019A (ko) 1987-02-28
ES8801517A1 (es) 1988-01-16
DK172227B1 (da) 1998-01-12
AU5308986A (en) 1986-07-01
JPH0751066A (ja) 1995-02-28
DK382786D0 (da) 1986-08-11
NO177678B (no) 1995-07-24

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B1 Patent granted (law 1993)
PUP Patent expired