DK397487D0 - 3-aryl-3-cycloalkyl-piperidin-2,6-dion-derivater, deres fremstilling og anvendelse - Google Patents
3-aryl-3-cycloalkyl-piperidin-2,6-dion-derivater, deres fremstilling og anvendelseInfo
- Publication number
- DK397487D0 DK397487D0 DK397487A DK397487A DK397487D0 DK 397487 D0 DK397487 D0 DK 397487D0 DK 397487 A DK397487 A DK 397487A DK 397487 A DK397487 A DK 397487A DK 397487 D0 DK397487 D0 DK 397487D0
- Authority
- DK
- Denmark
- Prior art keywords
- radical
- cycloalkyl
- piperidine
- aryl
- formula
- Prior art date
Links
- 229920004518 DION® Polymers 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- HSMPSHPWCOOUJH-UHFFFAOYSA-N anilinyl Chemical compound [NH]C1=CC=CC=C1 HSMPSHPWCOOUJH-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 125000003262 carboxylic acid ester group Chemical group [H]C([H])([*:2])OC(=O)C([H])([H])[*:1] 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 229940011871 estrogen Drugs 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- ZHCAAFJSYLFLPX-UHFFFAOYSA-N nitrocyclohexatriene Chemical compound [O-][N+](=O)C1=CC=C=C[CH]1 ZHCAAFJSYLFLPX-UHFFFAOYSA-N 0.000 abstract 1
- CNMOHEDUVVUVPP-UHFFFAOYSA-N piperidine-2,3-dione Chemical group O=C1CCCNC1=O CNMOHEDUVVUVPP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3625415 | 1986-07-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK397487D0 true DK397487D0 (da) | 1987-07-30 |
| DK397487A DK397487A (da) | 1988-02-01 |
Family
ID=6306099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK397487A DK397487A (da) | 1986-07-31 | 1987-07-30 | 3-aryl-3-cycloalkyl-piperidin-2,6-dion-derivater, deres fremstilling og anvendelse |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4839370A (da) |
| EP (1) | EP0258617B1 (da) |
| JP (1) | JPH0816100B2 (da) |
| AT (1) | ATE73774T1 (da) |
| DD (1) | DD264428A5 (da) |
| DE (2) | DE3724520C2 (da) |
| DK (1) | DK397487A (da) |
| ES (1) | ES2039217T3 (da) |
| FI (1) | FI85016C (da) |
| GR (1) | GR3004195T3 (da) |
| HU (1) | HU201740B (da) |
| IE (1) | IE60589B1 (da) |
| IL (1) | IL83367A (da) |
| NO (1) | NO170851C (da) |
| PT (1) | PT85456B (da) |
| ZA (1) | ZA875653B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5661014A (en) * | 1991-08-22 | 1997-08-26 | Chiroscience Limited | Chiral compounds and their resolution synthesis using enantioselective esterases |
| GB9410721D0 (en) * | 1994-05-27 | 1994-07-13 | Chiroscience Ltd | Chiral compounds and their resolution |
| CA2116108A1 (en) * | 1991-08-22 | 1993-03-04 | Christopher T. Evans | Chiral gultarate esters, their resolution and derived glutarimide compounds |
| NZ507504A (en) * | 1998-04-27 | 2003-07-25 | Praecis Pharm Inc | Methods for treating hot flashes and gynaecomastia |
| US6703367B1 (en) * | 1999-04-27 | 2004-03-09 | Praecis Pharmaceuticals Inc. | Methods for treating hot flashes and gynaecomastia |
| GB0120147D0 (en) * | 2001-08-17 | 2001-10-10 | Metris Therapeutics Ltd | Treatment method |
| US20100087402A1 (en) * | 2008-09-29 | 2010-04-08 | Vivus, Inc. | Methods and compositions for the treatment of estrogen-dependent hyperproliferative uterine disorders |
| DE102012002695B4 (de) | 2012-02-14 | 2024-08-01 | Zf Cv Systems Hannover Gmbh | Verfahren zur Ermittlung einer Notbremssituation eines Fahrzeuges |
| WO2024055112A1 (en) * | 2022-09-13 | 2024-03-21 | Risen (Suzhou) Pharma Tech Co., Ltd. | Bifunctional compounds and pharmaceutical uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA570974A (en) * | 1959-02-17 | Hoffmann Karl | Manufacture of 2:6-dioxo-piperidines | |
| DD16295A (da) * | ||||
| AT174909B (de) * | 1951-02-13 | 1953-05-26 | Ciba Geigy | Verfahren zur Herstellung neuer Dioxopiperidine |
| GB720198A (en) * | 1951-02-13 | 1954-12-15 | Ciba Ltd | Manufacture of new dioxopiperidines |
| US2848455A (en) * | 1955-07-18 | 1958-08-19 | Ciba Pharm Prod Inc | Alpha-(p-amino-phenyl)-alpha-lower alkyl glutarimides |
| US3057867A (en) * | 1960-06-11 | 1962-10-09 | Calandastiftung Inst Fur Wisse | Glutarimide derivatives |
| DE1445652A1 (de) * | 1961-09-07 | 1969-01-16 | Distillers Co Yeast Ltd | Neue Glutarimide und Verfahren zu deren Herstellung |
| US4668689A (en) * | 1984-07-19 | 1987-05-26 | National Research Development Corporation | Glutarimide derivatives for treating oestrogen-dependent tumors |
-
1987
- 1987-07-24 DE DE3724520A patent/DE3724520C2/de not_active Expired - Fee Related
- 1987-07-25 ES ES87110814T patent/ES2039217T3/es not_active Expired - Lifetime
- 1987-07-25 EP EP87110814A patent/EP0258617B1/de not_active Expired - Lifetime
- 1987-07-25 AT AT87110814T patent/ATE73774T1/de active
- 1987-07-25 DE DE8787110814T patent/DE3777500D1/de not_active Expired - Fee Related
- 1987-07-29 IL IL83367A patent/IL83367A/xx not_active IP Right Cessation
- 1987-07-30 PT PT85456A patent/PT85456B/pt not_active IP Right Cessation
- 1987-07-30 DD DD87305528A patent/DD264428A5/de not_active IP Right Cessation
- 1987-07-30 DK DK397487A patent/DK397487A/da not_active Application Discontinuation
- 1987-07-30 ZA ZA875653A patent/ZA875653B/xx unknown
- 1987-07-30 HU HU873520A patent/HU201740B/hu not_active IP Right Cessation
- 1987-07-30 NO NO873193A patent/NO170851C/no unknown
- 1987-07-30 FI FI873327A patent/FI85016C/fi not_active IP Right Cessation
- 1987-07-30 IE IE206987A patent/IE60589B1/en not_active IP Right Cessation
- 1987-07-30 JP JP62189068A patent/JPH0816100B2/ja not_active Expired - Lifetime
- 1987-07-31 US US07/079,964 patent/US4839370A/en not_active Expired - Fee Related
-
1992
- 1992-03-31 GR GR920400566T patent/GR3004195T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2039217T3 (es) | 1993-09-16 |
| NO873193L (no) | 1988-02-01 |
| US4839370A (en) | 1989-06-13 |
| NO170851B (no) | 1992-09-07 |
| FI85016C (fi) | 1992-02-25 |
| PT85456A (de) | 1987-08-01 |
| DE3724520C2 (de) | 1996-01-11 |
| IL83367A0 (en) | 1987-12-31 |
| ATE73774T1 (de) | 1992-04-15 |
| HU201740B (en) | 1990-12-28 |
| GR3004195T3 (da) | 1993-03-31 |
| JPS6341458A (ja) | 1988-02-22 |
| EP0258617B1 (de) | 1992-03-18 |
| DK397487A (da) | 1988-02-01 |
| EP0258617A1 (de) | 1988-03-09 |
| FI85016B (fi) | 1991-11-15 |
| IE60589B1 (en) | 1994-07-27 |
| NO170851C (no) | 1992-12-16 |
| IL83367A (en) | 1992-05-25 |
| PT85456B (pt) | 1990-06-29 |
| HUT44498A (en) | 1988-03-28 |
| NO873193D0 (no) | 1987-07-30 |
| ZA875653B (en) | 1988-02-15 |
| DE3724520A1 (de) | 1988-03-03 |
| FI873327L (fi) | 1988-02-01 |
| IE872069L (en) | 1988-01-31 |
| DD264428A5 (de) | 1989-02-01 |
| FI873327A0 (fi) | 1987-07-30 |
| DE3777500D1 (de) | 1992-04-23 |
| JPH0816100B2 (ja) | 1996-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |