DK398583D0 - Spergualin-beslaegtede forbindelser, fremgangsmader til fremstilling deraf samt deres anvendelse som laegemidler - Google Patents

Spergualin-beslaegtede forbindelser, fremgangsmader til fremstilling deraf samt deres anvendelse som laegemidler

Info

Publication number
DK398583D0
DK398583D0 DK3985/83A DK398583A DK398583D0 DK 398583 D0 DK398583 D0 DK 398583D0 DK 3985/83 A DK3985/83 A DK 3985/83A DK 398583 A DK398583 A DK 398583A DK 398583 D0 DK398583 D0 DK 398583D0
Authority
DK
Denmark
Prior art keywords
spergualin
medicines
procedures
preparing
related compounds
Prior art date
Application number
DK3985/83A
Other languages
English (en)
Other versions
DK160089C (da
DK398583A (da
DK160089B (da
Inventor
Hamao Umezawa
Tomio Takeuchi
Rinzo Nishizawa
Katsutoshi Takahashi
Teruya Nakamura
Yoshihisa Umeda
Original Assignee
Microbial Chem Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found
Publication of DK398583D0 publication Critical patent/DK398583D0/da
Publication of DK398583A publication Critical patent/DK398583A/da
Publication of DK160089B publication Critical patent/DK160089B/da
Application granted granted Critical
Publication of DK160089C publication Critical patent/DK160089C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK398583A 1982-09-02 1983-09-01 Analogifremgangsmaade til fremstilling af spergualinbeslaegtede forbindelser DK160089C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57151698A JPS5942356A (ja) 1982-09-02 1982-09-02 スパガリン関連化合物およびその製造法
JP15169882 1982-09-02

Publications (4)

Publication Number Publication Date
DK398583D0 true DK398583D0 (da) 1983-09-01
DK398583A DK398583A (da) 1984-03-03
DK160089B DK160089B (da) 1991-01-28
DK160089C DK160089C (da) 1991-06-24

Family

ID=15524303

Family Applications (1)

Application Number Title Priority Date Filing Date
DK398583A DK160089C (da) 1982-09-02 1983-09-01 Analogifremgangsmaade til fremstilling af spergualinbeslaegtede forbindelser

Country Status (14)

Country Link
US (1) US4529549A (da)
EP (1) EP0105193B1 (da)
JP (1) JPS5942356A (da)
KR (1) KR900008137B1 (da)
AR (1) AR241650A1 (da)
AT (1) ATE36701T1 (da)
AU (1) AU560073B2 (da)
CA (1) CA1199641A (da)
CS (1) CS235341B2 (da)
DE (1) DE3377795D1 (da)
DK (1) DK160089C (da)
ES (1) ES525278A0 (da)
HU (1) HU190730B (da)
MX (1) MX8257A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5862152A (ja) * 1981-10-08 1983-04-13 Microbial Chem Res Found Ｎ−〔４−（３−アミノプロピル）アミノブチル〕−２−（ω−グアニジノ脂肪酸アミド）−２−ヒドロキシエタンアミドおよびその誘導体ならびにその製造法
JPS61129119A (ja) * 1984-11-13 1986-06-17 Microbial Chem Res Found 新規免疫抑制剤
JPS61165322A (ja) * 1985-01-14 1986-07-26 Microbial Chem Res Found スパガリン類の注射用凍結乾燥製剤
JPH075538B2 (ja) * 1985-08-27 1995-01-25 財団法人微生物化学研究会 フエニレン基を有するスパガリン関連ニトリル化合物及びその製造法
EP0241797B1 (en) * 1986-04-04 1991-06-12 Microbial Chemistry Research Foundation Novel spergualin-related compounds and process for producing the same
US4873253A (en) * 1987-03-30 1989-10-10 Shosuke Okamoto Phenylalanine derivative and proteinase inhibitor
JPH0794424B2 (ja) * 1987-09-30 1995-10-11 財団法人微生物化学研究会 新スパガリン関連化合物およびその製造法
US5061787A (en) * 1988-06-24 1991-10-29 Nippon Kayaku Kabushiki Kaisha Novel spergualin-related compounds and compositions
JPH0776204B2 (ja) * 1988-07-01 1995-08-16 寳酒造株式会社 スパガリン類の精製法
US4879313A (en) * 1988-07-20 1989-11-07 Mosanto Company Novel platelet-aggregation inhibitors
DE69104291T2 (de) * 1990-07-20 1995-05-18 Nippon Kayaku Kk Spergulinähnliche Verbindungen und ihre Verwendung.
WO1994004140A1 (fr) * 1992-08-19 1994-03-03 Nippon Kayaku Kabushiki Kaisha Medicament anti-protozoose
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR2716451B1 (fr) * 1994-02-24 1996-04-26 Fournier Ind & Sante Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR2716452B1 (fr) * 1994-02-24 1996-05-10 Fournier Ind & Sante Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
DK0755380T3 (da) * 1995-02-10 1999-06-23 Fournier Ind & Sante 15-deoxyspergualin-analoge, deres terapeutiske anvendelse og fremgangsmåde til fremstilling deraf
FR2737891B1 (fr) * 1995-08-17 1997-10-24 Fournier Ind & Sante Analogues chiraux de la 15-deoxyspergualine, procede de preparation et utilisation en therapeutique
FR2730488B1 (fr) * 1995-02-10 1997-04-30 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur utilisation en therapeutique et leur procede de preparation
FR2734263B1 (fr) * 1995-05-17 1997-06-20 Fournier Ind & Sante Analogues de la 15-deoxyspergualine, leur procede de preparation et leur utilisation en therapeutique
US20020142000A1 (en) * 1999-01-15 2002-10-03 Digan Mary Ellen Anti-CD3 immunotoxins and therapeutic uses therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2051494B1 (da) * 1969-04-02 1974-04-12 Taiho Pharmaceutical Co Ltd
JPS507057B1 (da) * 1970-10-28 1975-03-20
US3937805A (en) * 1971-11-10 1976-02-10 Colgate-Palmolive Company Method of making dentifrice compositions containing insolubilized salts of 1,6-di-(p-chlorophenyl biguanido) hexane
JPS5748957A (en) * 1980-09-08 1982-03-20 Microbial Chem Res Found Novel antibiotic bmg 162-af2, its preparation and carcinostatic agent comprising it as active ingredient
FR2505328B1 (fr) * 1981-05-11 1985-06-21 Microbial Chem Res Found N-(4-(3-aminopropyl) aminobutyl)-2,2-dihydroxyethanamide et procede pour sa preparation

Also Published As

Publication number Publication date
DK160089C (da) 1991-06-24
EP0105193B1 (en) 1988-08-24
EP0105193A3 (en) 1985-04-03
KR900008137B1 (ko) 1990-10-31
MX8257A (es) 1994-01-31
KR840006332A (ko) 1984-11-29
AU560073B2 (en) 1987-03-26
US4529549A (en) 1985-07-16
DE3377795D1 (en) 1988-09-29
ES8506267A1 (es) 1985-07-01
HU190730B (en) 1986-10-28
AU1807483A (en) 1984-03-08
AR241650A1 (es) 1992-10-30
ES525278A0 (es) 1985-07-01
DK398583A (da) 1984-03-03
EP0105193A2 (en) 1984-04-11
DK160089B (da) 1991-01-28
ATE36701T1 (de) 1988-09-15
CA1199641A (en) 1986-01-21
JPH0149256B2 (da) 1989-10-24
CS235341B2 (en) 1985-05-15
JPS5942356A (ja) 1984-03-08

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