DK39892D0 - Peptid - Google Patents

Peptid

Info

Publication number
DK39892D0
DK39892D0 DK92398A DK39892A DK39892D0 DK 39892 D0 DK39892 D0 DK 39892D0 DK 92398 A DK92398 A DK 92398A DK 39892 A DK39892 A DK 39892A DK 39892 D0 DK39892 D0 DK 39892D0
Authority
DK
Denmark
Prior art keywords
glp
pct
agonists
receptor
sec
Prior art date
Application number
DK92398A
Other languages
Danish (da)
English (en)
Inventor
Bernard Thorens
Original Assignee
Bernard Thorens
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8093079&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK39892(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bernard Thorens filed Critical Bernard Thorens
Priority to DK92398A priority Critical patent/DK39892D0/da
Publication of DK39892D0 publication Critical patent/DK39892D0/da
Priority to DE69326405T priority patent/DE69326405T2/de
Priority to DE0586657T priority patent/DE586657T1/de
Priority to ES93906589T priority patent/ES2070801T1/es
Priority to PCT/EP1993/000697 priority patent/WO1993019175A1/en
Priority to AT93906589T priority patent/ATE184648T1/de
Priority to US08/142,439 priority patent/US5670360A/en
Priority to AU37512/93A priority patent/AU3751293A/en
Priority to JP51628793A priority patent/JP3371379B2/ja
Priority to EP93906589A priority patent/EP0586657B1/de
Priority to GR950300031T priority patent/GR950300031T1/el
Priority to US08/869,477 priority patent/US5846747A/en
Priority to US08/935,317 priority patent/US6051689A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/605Glucagons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK92398A 1992-03-25 1992-03-25 Peptid DK39892D0 (da)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK92398A DK39892D0 (da) 1992-03-25 1992-03-25 Peptid
EP93906589A EP0586657B1 (de) 1992-03-25 1993-03-23 Receptor für das Glucagon ähnliches Peptid-1 (GLP-1)
JP51628793A JP3371379B2 (ja) 1992-03-25 1993-03-23 グルカゴン様ペプチド−1(glp−1)に対するレセプター
AT93906589T ATE184648T1 (de) 1992-03-25 1993-03-23 Receptor für das glucagon ähnliches peptid-1 (glp-1)
DE0586657T DE586657T1 (de) 1992-03-25 1993-03-23 Receptor für das Glucagon ähnliches Peptid-1 (GLP-1).
ES93906589T ES2070801T1 (es) 1992-03-25 1993-03-23 Receptor para el peptido-1 similar al glucagon (glp-1).
PCT/EP1993/000697 WO1993019175A1 (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like-peptide-1 (glp-1)
DE69326405T DE69326405T2 (de) 1992-03-25 1993-03-23 Receptor für das Glucagon ähnliches Peptid-1 (GLP-1)
US08/142,439 US5670360A (en) 1992-03-25 1993-03-23 Mammalian receptors for glucagon-like-peptide-1 (GLP-1), corresponding DNA and recombinant expression systems, and screening assays for GLP-1 agonists and enhancers
AU37512/93A AU3751293A (en) 1992-03-25 1993-03-23 Receptor for the glucagon-like-peptide-1 (GLP-1)
GR950300031T GR950300031T1 (en) 1992-03-25 1995-06-30 Receptor for the glucagon-like-peptide-1 (glp-1).
US08/869,477 US5846747A (en) 1992-03-25 1997-06-05 Method for detecting glucagon-like peptide-1 antagonists and agonists
US08/935,317 US6051689A (en) 1992-03-25 1997-09-22 Receptor for the glucagon-like-peptide (GLP-1)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK92398A DK39892D0 (da) 1992-03-25 1992-03-25 Peptid

Publications (1)

Publication Number Publication Date
DK39892D0 true DK39892D0 (da) 1992-03-25

Family

ID=8093079

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92398A DK39892D0 (da) 1992-03-25 1992-03-25 Peptid

Country Status (10)

Country Link
US (2) US5670360A (de)
EP (1) EP0586657B1 (de)
JP (1) JP3371379B2 (de)
AT (1) ATE184648T1 (de)
AU (1) AU3751293A (de)
DE (2) DE586657T1 (de)
DK (1) DK39892D0 (de)
ES (1) ES2070801T1 (de)
GR (1) GR950300031T1 (de)
WO (1) WO1993019175A1 (de)

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US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US5846747A (en) * 1992-03-25 1998-12-08 Novo Nordisk A/S Method for detecting glucagon-like peptide-1 antagonists and agonists
DK39892D0 (da) * 1992-03-25 1992-03-25 Bernard Thorens Peptid
EP0969016A2 (de) * 1992-06-15 2000-01-05 Scios Inc. Dem Glukagon ähnliche Peptide und Insulinotropin-Derivate
HU219674B (hu) * 1992-08-28 2001-06-28 Novo Nordisk A/S Glukagon-receptort kódoló DNS-molekulák, glukagon-receptor peptidek, glukagon-receptort blokkoló monoklonális ellenanyagok, és eljárások előállításukra
US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
WO1995004821A1 (en) * 1993-08-09 1995-02-16 Merck & Co., Inc. Human glucagon-like 1 peptide receptor
GB9502830D0 (en) * 1995-02-14 1995-04-05 Ecole Polytech Regulation of polypeptide production in cells
US7048906B2 (en) 1995-05-17 2006-05-23 Cedars-Sinai Medical Center Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
DE69737561T2 (de) * 1996-12-13 2008-03-06 Nps Allelix Corp., Toronto Klonierte rezeptoren des glukagon-ähnlichen peptids-2
US8592553B2 (en) 1996-12-13 2013-11-26 Nps Pharmaceuticals, Inc. Cloned glucagon-like peptide-2 receptors
ATE251465T1 (de) 1998-07-31 2003-10-15 Novo Nordisk As In-vitro stimulation von beta zellen vermehrung
JP2002528721A (ja) * 1998-10-23 2002-09-03 グラクソ グループ リミテッド 核内受容体のリガンド用のアッセイ
ES2253353T3 (es) 2000-03-08 2006-06-01 Novo Nordisk A/S Reduccion del colesterol serico.
US6448045B1 (en) 2000-03-10 2002-09-10 The Regents Of The University Of California Inducing insulin gene expression in pancreas cells expressing recombinant PDX-1
US20020123071A1 (en) * 2000-12-04 2002-09-05 Knudsen Sanne Moller Method of identifying compounds capable of acting as agonists or antagonists of G-protein coupled receptors
US6642003B2 (en) 2001-08-02 2003-11-04 Cedars-Sinai Medical Center Human glucose-dependent insulin-secreting cell line
CN100350968C (zh) 2001-09-24 2007-11-28 皇家创新有限公司 饮食行为的改进
US6911324B2 (en) * 2001-10-18 2005-06-28 The Regents Of The University Of California Induction of beta cell differentiation in human cells
EP1474163A2 (de) 2002-01-10 2004-11-10 Imperial College Innovations Limited Veränderung des fütterungsverhaltens
US7141240B2 (en) * 2002-03-12 2006-11-28 Cedars-Sinai Medical Center Glucose-dependent insulin-secreting cells transfected with a nucleotide sequence encoding GLP-1
WO2004005342A1 (en) 2002-07-04 2004-01-15 Zealand Pharma A/S Glp-1 and methods for treating diabetes
BR0314996A (pt) * 2002-10-02 2005-08-09 Zealand Pharma As Composição, composição farmaceuticamente aceitável, método para produzir a composição, métodos para estabilizar a exendina-4 (1-39) ou uma sua variante, derivado ou análogo contra a degradação, antes, durante ou após o uso pretendido, para tratar doenças, para tratar de estados de doenças associados com nìveis elevados de glicose do sangue, para a regulação dos nìveis de glicose do sangue, para a regulação do esvaziamento gástrico, para estimular a liberação de insulina em um mamìfero para reduzir o nìvel de glicose do sangue em um mamìfero, para reduzir o nìvel de lipìdeos plasmáticos em um mamìfero, para reduzir a mortalidade e a morbidez após o infarto miocárdico em um mamìfero, para estimular a liberação de insulina em um mamìfero, e para produzir uma exendina (1-39) estabilizada, e, exendina (1-39) estabilizada
US20040209803A1 (en) * 2002-12-19 2004-10-21 Alain Baron Compositions for the treatment and prevention of nephropathy
US7790681B2 (en) * 2002-12-17 2010-09-07 Amylin Pharmaceuticals, Inc. Treatment of cardiac arrhythmias with GLP-1 receptor ligands
GB0300571D0 (en) 2003-01-10 2003-02-12 Imp College Innovations Ltd Modification of feeding behaviour
WO2004071393A2 (en) * 2003-02-13 2004-08-26 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with glucagon-like peptide 1 receptor (glp1r)
WO2005018536A2 (en) * 2003-05-23 2005-03-03 Human Genome Sciences, Inc. Agonist antibodies that specifically bind the glucagon like peptide-1 receptor
DK3300721T4 (da) 2003-11-20 2025-03-03 Novo Nordisk As Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger
EP2298337B1 (de) 2003-12-09 2017-02-22 Novo Nordisk A/S Regulierung des bevorzuchtes nahrungsaufnahmen mit verwendung von GLP-1 agonisten
EP1758575A1 (de) 2004-06-11 2007-03-07 Novo Nordisk A/S Bekämpfung von arzneimittel-induzierter fettleibigkeit unter verwendung von glp-1-agonisten
WO2006133333A2 (en) 2005-06-07 2006-12-14 The Rockefeller University Stimulation of pancreatic b cell proliferation
TWI428346B (zh) 2006-12-13 2014-03-01 Imp Innovations Ltd 新穎化合物及其等對進食行為影響
US8718994B2 (en) * 2008-04-09 2014-05-06 Transtech Pharma, Llc Ligands for the GLP-1 receptor and methods for discovery thereof
RS59913B1 (sr) 2008-10-17 2020-03-31 Sanofi Aventis Deutschland Kombinacija insulina i glp-1-agonista
CN102596175A (zh) 2009-07-06 2012-07-18 赛诺菲-安万特德国有限公司 含有甲硫氨酸的水性胰岛素制备物
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MY180661A (en) 2009-11-13 2020-12-04 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist, an insulin and methionine
WO2011123943A1 (en) 2010-04-09 2011-10-13 Mount Sinai Hospital Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
CN107129538B (zh) 2010-04-27 2021-07-16 西兰制药公司 Glp-1受体激动剂和胃泌素的肽缀合物及其用途
PL2611458T3 (pl) 2010-08-30 2017-02-28 Sanofi-Aventis Deutschland Gmbh Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
SI2651398T1 (en) 2010-12-16 2018-04-30 Novo Nordisk A/S SOLID COMPOSITIONS CONTAINING GLP-1 AGONIST AND SOL N- (8- (2-HYDROXYBENZOIL) AMINO) CAPRICULATE ACIDS
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
AR087693A1 (es) 2011-08-29 2014-04-09 Sanofi Aventis Deutschland Combinacion farmaceutica para uso en el control glucemico en pacientes con diabetes de tipo 2
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
TW201326194A (zh) 2011-11-03 2013-07-01 Zealand Pharma As Glp-1胃泌素受體促效劑肽結合物
EP2788027A2 (de) 2011-12-09 2014-10-15 Novo Nordisk A/S Glp-1-agonisten
HRP20181447T1 (hr) 2012-03-22 2018-11-02 Novo Nordisk A/S Pripravci glp-1 peptida i njihova priprava
ES2965469T3 (es) 2012-03-22 2024-04-15 Novo Nordisk As Composiciones que comprenden un agente de suministro y preparación de estas
EP2866825B1 (de) 2012-07-01 2020-04-08 Novo Nordisk A/S Verwendung von glp-1-peptiden mit langzeitwirkung
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TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
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TWI780236B (zh) 2013-02-04 2022-10-11 法商賽諾菲公司 胰島素類似物及/或胰島素衍生物之穩定化醫藥調配物
US9988429B2 (en) 2013-10-17 2018-06-05 Zealand Pharma A/S Glucagon analogues
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WO2015067715A2 (en) 2013-11-06 2015-05-14 Zealand Pharma A/S Gip-glp-1 dual agonist compounds and methods
CN105829339B (zh) 2013-11-06 2021-03-12 西兰制药公司 胰高血糖素-glp-1-gip三重激动剂化合物
BR112016015851A2 (pt) 2014-01-09 2017-08-08 Sanofi Sa Formulações farmacêuticas estabilizadas de insulina aspart
MX2016008979A (es) 2014-01-09 2016-10-04 Sanofi Sa Formulaciones farmaceuticas estabilizadas de analogos de insulina y/o derivados de insulina.
MX2016008978A (es) 2014-01-09 2016-10-04 Sanofi Sa Formulaciones farmaceuticas de analogos de insulina y/o derivados de insulina estabilizadas y que estan libres de glicerol.
ES2630106T3 (es) 2014-10-07 2017-08-18 Cyprumed Gmbh Formulaciones farmacéuticas para la administración oral de fármacos peptídicos o proteicos
KR102620911B1 (ko) 2014-10-29 2024-01-05 질랜드 파마 에이/에스 Gip 효능제 화합물 및 방법
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TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
DK3283507T3 (da) 2015-04-16 2020-01-02 Zealand Pharma As Acyleret glucagonanalog
JP2018529749A (ja) 2015-10-07 2018-10-11 シプルメット・ゲーエムベーハー ペプチド薬物を経口送達するための医薬製剤
WO2018065634A1 (en) 2016-10-07 2018-04-12 Cyprumed Gmbh Pharmaceutical compositions for the nasal delivery of peptide or protein drugs
EP3551651B1 (de) 2016-12-09 2024-03-06 Zealand Pharma A/S Acylierte glp-1/glp-2 duale agoniste
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
JP6898518B2 (ja) 2018-02-02 2021-07-07 ノヴォ ノルディスク アー/エス Glp−1アゴニスト、n−(8−(2−ヒドロキシベンゾイル)アミノ)カプリル酸の塩及び滑沢剤を含む固形組成物
WO2019193204A1 (en) 2018-04-06 2019-10-10 Cyprumed Gmbh Pharmaceutical compositions for the transmucosal delivery of therapeutic peptides and proteins
TWI829687B (zh) 2018-05-07 2024-01-21 丹麥商諾佛 儂迪克股份有限公司 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物
CN111423506B (zh) * 2019-11-08 2023-06-27 成都奥达生物科技有限公司 一种glp-1化合物
JP7761567B2 (ja) 2020-02-18 2025-10-28 ノヴォ ノルディスク アー/エス 医薬製剤
US11478533B2 (en) 2020-04-27 2022-10-25 Novo Nordisk A/S Semaglutide for use in medicine
CN115461044B (zh) 2020-04-29 2025-06-10 诺和诺德股份有限公司 包含glp-1激动剂和组氨酸的固体组合物
EP4210680A1 (de) 2020-09-07 2023-07-19 Cyprumed GmbH Verbesserte pharmazeutische formulierungen von glp-1-rezeptoragonisten
WO2023012263A1 (en) 2021-08-04 2023-02-09 Novo Nordisk A/S Solid oral peptide formulations
JP2026502943A (ja) 2022-12-30 2026-01-27 アルギファルマ エーエス 経口投与されるポリペプチド治療剤の全身バイオアベイラビリティを高める組成物および方法
WO2024165571A2 (en) 2023-02-06 2024-08-15 E-Therapeutics Plc Inhibitors of expression and/or function
WO2025125576A2 (en) 2023-12-15 2025-06-19 E-Therapeutics Plc Inhibitors of expression and/or function
EP4686757A1 (de) 2024-07-31 2026-02-04 e-therapeutics PLC Inhibitoren der expression und/oder funktion
WO2025133348A1 (en) 2023-12-22 2025-06-26 E-Therapeutics Plc Inhibitors of expression and/or function
WO2025196502A1 (en) 2024-03-20 2025-09-25 North Carolina Agricultural & Technical State University Choline kinase inhibitors as a therapeutic treatment for obesity
DK182293B1 (en) 2025-01-16 2026-02-25 Novo Nordisk As Semaglutide for use in medical therapy including weight management

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK39892D0 (da) * 1992-03-25 1992-03-25 Bernard Thorens Peptid

Also Published As

Publication number Publication date
AU3751293A (en) 1993-10-21
US6051689A (en) 2000-04-18
JP3371379B2 (ja) 2003-01-27
ATE184648T1 (de) 1999-10-15
EP0586657B1 (de) 1999-09-15
US5670360A (en) 1997-09-23
DE69326405T2 (de) 2000-03-23
WO1993019175A1 (en) 1993-09-30
GR950300031T1 (en) 1995-06-30
DE586657T1 (de) 1996-01-18
EP0586657A1 (de) 1994-03-16
ES2070801T1 (es) 1995-06-16
JPH06508765A (ja) 1994-10-06
DE69326405D1 (de) 1999-10-21

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